Clinical Efficacy of Treatment Procedures in Endodontic Infection Control and One Year Follow-Up of Periapical Healing

Introduction: The radiographic control of the root canal treatment can evaluate the healing of the periapical lesions. The objective of this study was to determinate the characteristics of the radiographic healing that was observed after one year, during follow-up sessions; so, the healing of the lesions according to the periapical pathology at the beginning of the treatment and the causes of failure of the endodontic treatments were recorded.Method: This is a prospective, observational, descriptive and longitudinal study, carried out in patients who attended control one year after endodontic treatment through the Periapical Index (PAI).Results: A total of 395 teeth of patients who underwent endodontic treatment one year prior to data collection, 87 presented radiogaphically observable periapical lesions; of these, 40 (45.97%) attended the control at one year. The frequency of cases in which some degree of radiographic healing was observed one year after treatment was 97.46%. The pathology with more cases of complete healing was periodontitis with sinus tract. In general, 84.61% of the cases decreased two levels in their PAI after one year. The 100% of the cases of failure presented vertical root fractures.Conclusion: The frequency of periapical healing after endodontic treatment is high. The main cause for the failure of the treatments documented in this study was the lack of coronal restoration that caused vertical fractures.

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Clinical efficacy of the smartplug™ in the treatment of primary Sjogren’s syndrome with keratoconjunctivitis SICCA: one-year follow-up study

Rheumatology International ◽

10.1007/s00296-010-1527-x ◽

2010 ◽

Vol 31 (12) ◽

pp. 1567-1570 ◽

Cited By ~ 14

Author(s):

Sait Egrilmez ◽

Fatih Aslan ◽

Gonca Karabulut ◽

Yasemin Kabasakal ◽

Ayse Yagci

Keyword(s):

Clinical Efficacy ◽

Keratoconjunctivitis Sicca ◽

Sjogren’S Syndrome ◽

Sjogren's Syndrome ◽

Primary Sjögren’S Syndrome ◽

Primary Sjogren’S Syndrome ◽

Primary Sjögren's Syndrome ◽

Follow Up Study ◽

One Year

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Clinical Efficacy and Imaging Analysis for the Surgical Treatment of Thoracolumbar Infections in Elderly Patients

10.21203/rs.3.rs-269772/v1 ◽

2021 ◽

Author(s):

Yanlong Zhong ◽

Benyu Tang ◽

Qi Lai ◽

Yonghong Sheng ◽

Chao Li ◽

...

Keyword(s):

Surgical Treatment ◽

Elderly Patients ◽

Clinical Efficacy ◽

Short Form ◽

Effective Measure ◽

Imaging Results ◽

Sf 36 ◽

Operative Complications ◽

One Year

Abstract BackgroundFew reports have been conducted to comparing surgical results and safety evaluations between the different types of infections in geriatric patients. The aim of this study is to investigate the safety and efficacy of surgical treatment for thoracolumbar infections in elderly patients.Methods21 patients with pyogenic spondylodiscitis (PS) and 26 patients with tuberculous spondylodiscitis (TS) were enrolled in the study. All patients were treated using one-stage posterior debridement, decompression, and pedicle screw fixation. Comparison of operative safety parameters between the two groups. Clinical efficacy was evaluated using visual analog scale (VAS) score, the American Spinal Injury Association (ASIA) grade, the short form (SF)-36 survey and Oswestry disability index (ODI) to determine patient quality of life pre- and post-operatively. Results Hospitalisation and intensive care unit duration in the PS group were significantly shorter than in the TS group (P<0.05). The total incidence of post-operative complications for both groups was 44.7%. More complications occurred in the TS group, but the difference was not significant. The VAS and SF-36 scores (physical component) were significantly better in the PS group six months post-operatively, and the SF-36 (mental component) scores were significantly better in the PS group at the one-year follow-up. Neurological status in both groups improved post-operatively, and 83% of the patients were satisfied with the results of their operation. Imaging results showed that bone graft fusion improved in both groups at six months, one year and at the final follow-up. ConclusionSurgical treatment can provide satisfactory clinical and imaging results for thoracolumbar infection in patients over 65 years old. Although the incidence of peri-operative complications in the elderly is high, it is controllable and surgical treatment remains a safe and effective measure.

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Clinical Efficacy of Naltrexone: A One Year Follow Up

PsycEXTRA Dataset ◽

10.1037/e497452006-021 ◽

1976 ◽

Cited By ~ 1

Author(s):

Richard Resnick ◽

Michael Aronoff ◽

Greta Lonborg ◽

Richard Kestenbaum ◽

Frank Kauders ◽

...

Keyword(s):

Clinical Efficacy ◽

One Year

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An open-label prospective clinical study of the efficacy and tolerability of brand-name and generic levetiracetam in the monotherapy of focal epilepsy in adults

Neurology neuropsychiatry Psychosomatics ◽

10.14412/2074-2711-2018-1s-12-17 ◽

2018 ◽

Vol 10 (1S) ◽

pp. 12-17 ◽

Cited By ~ 2

Author(s):

V. A. Karlov ◽

P. N. Vlasov ◽

I. A. Zhidkova

Keyword(s):

Clinical Efficacy ◽

Focal Epilepsy ◽

Clinical Results ◽

Prospective Clinical Study ◽

Brand Name ◽

Open Label ◽

International Nonproprietary Name ◽

Group 2 ◽

One Year

Objective: to comparatively evaluate the clinical efficacy and tolerability of monotherapy with levetiracetam (LEV), a brand-name drug (bLEV; Keppra, UCB Pharma, Belgium) and its generic (gLEV; Epiterra, TEVA, Israel) in adolescent (over 16 years of age) and adult patients with focal epilepsy (FE) during a one-year follow-up period.Patients and methods. The patients were divided into two groups: 1) bLEV (n = 143) and 2) gLEV (n = 63). Group 2 received monotherapy with gLEV at baseline, or was switched to it from another drug within the international nonproprietary name, or to LEV from monotherapy with another antiepileptic drug (AED) due to inefficiency and/or poor tolerability. The median doses of bLEV and gLEV were 1000 and 1500 mg/day, respectively.Results and discussion. The results of the clinical trial suggest that LEV shows high efficacy and excellent tolerance in FE therapy. The clinical efficacy of bLEV and gLEV at 12-month follow-up was high and amounted to 82.5% for the two dosage forms. The frequency of adverse events was 17.5% for both bLEV and gLEV. The median dose of LEV was 1000 mg/day for Group 1 and 1500 mg/day for Group 2. Higher LEV doses in Group 2 patients were probably due to their longer disease duration. All patients taking LEV had an excellent or good quality of life and, when switched from other AEDs, showed even an improvement. The comparability of clinical results suggests that there may be bLEV to gLEV and gLEV to bLEV switches, especially during forced drug supply disruptions; however, this substitution should be done only after mandatorily discussing this matter with the patient and telling him about all possible consequences of this substitution.

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Temporary Mental Nerve Paresthesia Originating from Periapical Infection

Case Reports in Dentistry ◽

10.1155/2015/457645 ◽

2015 ◽

Vol 2015 ◽

pp. 1-4

Author(s):

Ozgur Genc Sen ◽

Volkan Kaplan

Keyword(s):

Antibiotic Therapy ◽

Root Canal ◽

Complete Healing ◽

Periapical Lesion ◽

Mental Nerve ◽

Local Factors ◽

Endodontic Infection ◽

Dental Origin ◽

One Year

Many systemic and local factors can cause paresthesia, and it is rarely caused by infections of dental origin. This report presents a case of mental nerve paresthesia caused by endodontic infection of a mandibular left second premolar. Resolution of the paresthesia began two weeks after conventional root canal treatment associated with antibiotic therapy and was completed in eight weeks. One year follow-up radiograph indicated complete healing of the radiolucent periapical lesion. The tooth was asymptomatic and functional.

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Clinical Efficacy and Imaging Analysis for the Surgical Treatment of Thoracolumbar Infections in Elderly Patients

10.21203/rs.3.rs-269772/v2 ◽

2021 ◽

Author(s):

Yanlong Zhong ◽

Benyu Tang ◽

Qi Lai ◽

Yonghong Sheng ◽

Chao Li ◽

...

Keyword(s):

Surgical Treatment ◽

Clinical Efficacy ◽

Spinal Injury ◽

Short Form ◽

Effective Measure ◽

Imaging Results ◽

Sf 36 ◽

Operative Complications ◽

One Year

Abstract BackgroundFew reports have been conducted to comparing surgical results and safety evaluations between the different types of infections in geriatric patients. The aim of this study is to investigate the safety and efficacy of surgical treatment for thoracolumbar infections in elderly patients.Methods21 patients with pyogenic spondylodiscitis (PS) and 26 patients with tuberculous spondylodiscitis (TS) were enrolled in the study. All patients were treated using one-stage posterior debridement, decompression, and pedicle screw fixation. Comparison of operative safety parameters between the two groups. Clinical efficacy was evaluated using visual analog scale (VAS) score, the American Spinal Injury Association (ASIA) grade, the short form (SF)-36 survey and Oswestry disability index (ODI) to determine patient quality of life pre- and post-operatively. Results Hospitalisation and intensive care unit duration in the PS group were significantly shorter than in the TS group (P<0.05). The total incidence of post-operative complications for both groups was 44.7%. More complications occurred in the TS group, but the difference was not significant. The VAS and SF-36 scores (physical component) were significantly better in the PS group six months post-operatively, and the SF-36 (mental component) scores were significantly better in the PS group at the one-year follow-up. Neurological status in both groups improved post-operatively, and 83% of the patients were satisfied with the results of their operation. Imaging results showed that bone graft fusion improved in both groups at six months, one year and at the final follow-up. ConclusionSurgical treatment can provide satisfactory clinical and imaging results for thoracolumbar infection in patients over 65 years old. Although the incidence of peri-operative complications in the elderly is high, it is controllable and surgical treatment remains a safe and effective measure.

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