DOES ELEVATED ALDOSTERONE IN OBSTRUCTIVE SLEEP APNOEA REPRESS SURFACTANT PROTEIN-B IN MIDDLE-AGED MALES? A CROSS-SECTIONAL STUDY

2018 ◽  
Vol 36 (Supplement 1) ◽  
pp. e271
Author(s):  
A. Abulimiti ◽  
N. Li ◽  
Q. Luo
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Surfactant Protein ◽  
Cross Sectional Study ◽  
Sleep Apnoea ◽  
Sectional Study ◽  
Middle Aged ◽  
Cross Sectional ◽  
Surfactant Protein B ◽  
Obstructive Sleep ◽  
Protein B

GENETIC POLYMORPHISMS OF SURFACTANT PROTEIN-B AND RISK OF OBSTRUCTIVE SLEEP APNOEA

2018 ◽  
Vol 36 (Supplement 1) ◽  
pp. e205
Author(s):  
N. Li ◽  
Y. He ◽  
X. Yao ◽  
M. Heizhati ◽  
Y. Wang ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Obstructive Sleep Apnoea ◽  
Surfactant Protein ◽  
Sleep Apnoea ◽  
Surfactant Protein B ◽  
Obstructive Sleep ◽  
Protein B

Prevalence of obstructive sleep apnoea following head and neck cancer treatment: A cross-sectional study

Oral Oncology ◽  
2006 ◽  
Vol 42 (1) ◽  
pp. 107-113 ◽  
Author(s):  
Willem Nesse ◽  
Aarnoud Hoekema ◽  
Boudewijn Stegenga ◽  
Johannes H. van der Hoeven ◽  
Lambert G.M. de Bont ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Obstructive Sleep Apnoea ◽  
Neck Cancer ◽  
Cross Sectional Study ◽  
Sleep Apnoea ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obstructive Sleep

scholarly journals Comorbidity patterns and associated characteristics in children with obstructive sleep apnoea–hypopnoea syndrome in Shanghai, China: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e053007
Author(s):  
Ziyun Li ◽  
Xiang Gao ◽  
Ning Chen ◽  
Liang Zhou ◽  
Hui Wang ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Otitis Media ◽  
Obstructive Sleep Apnoea ◽  
Cross Sectional Study ◽  
Sleep Apnoea ◽  
Sectional Study ◽  
Cross Sectional ◽  
Chronic Rhinitis ◽  
Obstructive Sleep ◽  
The One

ObjectivesPaediatric obstructive sleep apnoea–hypopnoea syndrome (OSAHS), which usually cooccurs with various diseases, significantly impacts health and social resources. Domestic paediatric OSAHS studies have not included comorbidity patterns or distribution characteristics. Thus, we investigated the comorbid characteristics of paediatric OSAHS in Shanghai, China.DesignLarge hospital-based cross-sectional study.SettingPaediatric ward medical data from the Pudong New Area, Shanghai, China from 2013 to 2016.Participants4045 Chinese children aged 0–18 years.Primary and secondary outcome measuresPaediatric OSAHS was diagnosed using the Paediatric Sleep Questionnaire with a cut-off score of 8 points. The outcomes were comorbidity patterns and their characteristics. χ2 tests were performed to compare differences among the top comorbidity patterns.ResultsMajor comorbidities were otolaryngological morbidities. Among one-comorbidity patterns, OSAHS+chronic rhinitis (37.53%) and OSAHS+allergic rhinitis (28.13%) were most common. Among two-comorbidity patterns, OSAHS+chronic rhinitis +chronic exudative otitis media (10.88%), OSAHS+allergic rhinitis +chronic exudative otitis media (7.94%), OSAHS+allergic rhinitis +chronic tonsillitis (4.43%) and OSAHS+chronic rhinitis +chronic tonsillitis (4.23%) were most common. Males predominated in all comorbidity groups. Age differences for the top five patterns in both the one-comorbidity (p=0.035) and two comorbidities (p<0.001) groups were statistically significant. In the one-comorbidity group, patients were more likely to have one operation (p<0.001), and in the two comorbidities group, patterns of ‘OSAHS+chronic rhinitis +chronic exudative otitis media’ and ‘OSAHS+allergic rhinitis +chronic exudative otitis media’ were more common in the ≥2 operations group (p<0.001). Notably, the top five patterns of the 2-comorbidities group were significantly associated with the length of stay (LOS) (p<0.001), while those in the one-comorbidity group were not.ConclusionOSAHS+rhinitis (chronic rhinitis or allergic rhinitis) was the most common diagnosis. Age, number of operations, and LOS are significantly associated with the patterns. This emphasises the importance of better understanding complex otolaryngological comorbidity diagnoses and treatments in paediatric OSAHS to reverse clinical outcomes and save health resources.

scholarly journals Translation and validation of the STOP-Bang questionnaire into Slovene

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Andrej Pangerc ◽  
Marija Petek Šter ◽  
Leja Dolenc Grošelj
Keyword(s):  
Healthy Subjects ◽  
Cross Sectional Study ◽  
Sleep Apnoea ◽  
Sectional Study ◽  
Validation Group ◽  
Cross Sectional ◽  
Sleep Study ◽  
Obstructive Sleep ◽  
Test Retest Reliability ◽  
Translation And Validation

Abstract Purpose To translate, culturally adapt and evaluate the Slovene version of the STOP-Bang questionnaire (SBQ) for use in the sleep clinic. Methods Standard forward–backward translation and harmonisation of the Slovene translation of the SBQ were performed. Test–retest reliability was performed on a sample of healthy subjects. A cross-sectional study was performed with patients referred for a sleep study. Patients filled out the Slovene translation of the SBQ before undergoing sleep study. Results The validation group consisted of 256 patients, of which 237 (92.6%) were included. Mean age was 52.5 ± 14.6, 63.3% of patients were male. Obstructive sleep apnoea (OSA) (apnoea–hypopnea index (AHI) ≥ 5) was present in 69.6% of patients, of whom 22.4% had mild (AHI ≥ 5 and < 15), 21.9% moderate (AHI ≥ 15 and < 30), and 25.3% severe (AHI ≥ 30) OSA. A SBQ score of 3 had a sensitivity of 92.1 (86.9–95.7), specificity of 44.4 (32.7–56.6), PPV of 79.2 (75.5–82.4) and AUC of 0.757 (95% CI 0.692–0.823; p < 0.001) for all OSA (AHI ≥ 5). Each increase in the SBQ score was associated with an increase in the probability of OSA. Conclusion This study shows that the Slovene version of the SBQ is a valid tool for evaluating the risk of OSA in a sleep clinic.

scholarly journals Sleep pattern, sleep problems and comorbidities among resident doctors at a tertiary care institution in India: a cross sectional study

2017 ◽  
Vol 4 (12) ◽  
pp. 4477 ◽  
Author(s):  
Siddalingaiah H.S. ◽  
Chandrakala D. ◽  
Amarjeet Singh
Keyword(s):  
Sleep Problems ◽  
Tertiary Care ◽  
Sleep Time ◽  
Cross Sectional Study ◽  
Sleep Apnoea ◽  
Sleep Pattern ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Study Results

Background: Sleep problems are a major concern in population working under stress such as resident doctors. Sleep has many health benefits; sleep problems are linked with short and long term adverse health outcomes. Aim was to study sleep pattern, problems and comorbidities among resident doctors. Methods: A cross-sectional study design with a pre-validated sleep assessment proforma was used to collect information on socio-demographics, sleep pattern, sleep problems and comorbidities from 428 resident doctors found eligible for the study. Results: 350 subjects returned the filled proforma (82% response rate). Mean daily sleep hours were 6.21 (SD, 1.39) and work hours 12.77 (SD, 3.63). Sleep time was night in 64.6%, day in 12%, and both in 23.4%. Monthly average of 5.8 night shifts and 2.03 duty offs were found. Visual analogue scale (0-10) mean scores for sleepiness and tiredness were 4.41 (SD, 2.55; 95% CI, 4.14-4.68; P<0.01) and 4.73 (SD, 2.62; 95% CI, 4.45-5.00; P<0.01) respectively. Presence of different symptoms related to sleep problems ranged from 7 to 26% and various problems interfering with sleep ranged from 10 to 25%. Comorbidities such as allergy (29.4%), jerky legs (24.3%), sinus infections (22.8%), restless leg syndrome (16.3%), snoring (8.3%), asthma/lung diseases (5.8%), chronic diseases (3.4%), severe snoring disturbing others (1.8%), and obstructive sleep apnoea (0.9%) were present. Conclusions: Sleep problems were highly prevalent among resident doctors. The resident doctors were sleep-deprived, overworked, tired, excessively sleepy, and had significant presence of factors affecting circadian rhythm and sleep fragmentation. Various comorbidities were also present with varying prevalence. 

scholarly journals Predisposing Factors and Surgical Management of Obstructive Sleep Apnoea in Children

2019 ◽  
Vol 46 (2) ◽  
pp. 22-25
Author(s):  
Syed Hasan Imam Al-Masum ◽  
Syed AM Asfarul Abedin ◽  
Anup Kumar Chowdhury ◽  
Bishwojit Kumar Saha ◽  
Md Nazmul Islam ◽  
...  
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Upper Airway ◽  
Cross Sectional Study ◽  
Sleep Apnoea ◽  
Outcome Data ◽  
Child Growth ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Obstructive Sleep

Obstructive sleep apnoea (OSA) is a condition characterized by episodic partial or complete obstruction of the upper airway during sleep. This cause apnoea or cessation of breathing. During sleep, muscles around the airway relax causing the throat and upper airway to narrow. This leads to snoring, but it can also lead to the airway being blocked. Trying to breathe against a blocked airway causes oxygen levels to fall and carbon dioxide to rise. This cross-sectional study was conducted in Department of ENT, Dhaka Shishu (Children) Hospital and Dhaka Medical College Hospital from April to September’2015. The purpose of the study was to prevent significant morbidity and enhancement of child growth. One hundred children of OSA were studied by detail history and clinical examination. All children whose parents consulted their ENT surgeon in Dhaka Shishu(Children) Hospital and DMCH for snoring or laboured breathing during sleep (nocturnal sweating particularly in the nuchal area, unusual sleeping positions, restless sleep, awakening and excessive movements, intercostals recession and dry mouth) were included in the study. More common predisposing conditions for OSA were obesity and Craniofacial anomalies which were 34% and 27% respectively. In present study most of the children (73%) were managed by Adenotonsillectomy and 27% children were manage by Adenoidectomy. Outcome data have demonstrated that surgical therapy can be successful in the treatment of OSA. Bangladesh Med J. 2017 May; 46 (2): 22-25

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