Poster 16: Mechanical Properties of Vaginal Versus Abdominal Surgical Wound Healing in a Rabbit Model

2005 ◽  
Vol 11 (Supplement 1) ◽  
pp. S33
Author(s):  
Y Abramov ◽  
J R. Miller ◽  
A Alshahrour ◽  
A Webb ◽  
G A. Ameer ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Rabbit Model ◽  
Surgical Wound

Histologic characterization of vaginal vs. abdominal surgical wound healing in a rabbit model

2007 ◽  
Vol 15 (1) ◽  
pp. 80-86 ◽  
Author(s):  
Yoram Abramov ◽  
Barbara Golden ◽  
Megan Sullivan ◽  
Sylvia M. Botros ◽  
Jay-James R. Miller ◽  
...  
Keyword(s):  
Wound Healing ◽  
Rabbit Model ◽  
Surgical Wound

scholarly journals Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2104
Author(s):  
Sibusiso Alven ◽  
Blessing Atim Aderibigbe
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Vinyl Alcohol ◽  
Wound Dressing ◽  
Chronic Wounds ◽  
Cellular Adhesion ◽  
Wound Dressings ◽  
Poly Vinyl Alcohol ◽  
High Porosity ◽  
Hybrid Nanofibers

The management of chronic wounds is challenging. The factors that impede wound healing include malnutrition, diseases (such as diabetes, cancer), and bacterial infection. Most of the presently utilized wound dressing materials suffer from severe limitations, including poor antibacterial and mechanical properties. Wound dressings formulated from the combination of biopolymers and synthetic polymers (i.e., poly (vinyl alcohol) or poly (ε-caprolactone) display interesting properties, including good biocompatibility, improved biodegradation, good mechanical properties and antimicrobial effects, promote tissue regeneration, etc. Formulation of these wound dressings via electrospinning technique is cost-effective, useful for uniform and continuous nanofibers with controllable pore structure, high porosity, excellent swelling capacity, good gaseous exchange, excellent cellular adhesion, and show a good capability to provide moisture and warmth environment for the accelerated wound healing process. Based on the above-mentioned outstanding properties of nanofibers and the unique properties of hybrid wound dressings prepared from poly (vinyl alcohol) and poly (ε-caprolactone), this review reports the in vitro and in vivo outcomes of the reported hybrid nanofibers.

scholarly journals Investigation of the biological activity, mechanical properties and wound healing application of a novel scaffold based on lignin–agarose hydrogel and silk fibroin embedded zinc chromite nanoparticles

RSC Advances ◽  
2021 ◽  
Vol 11 (29) ◽  
pp. 17914-17923
Author(s):  
Reza Eivazzadeh-Keihan ◽  
Hooman Aghamirza Moghim Aliabadi ◽  
Fateme Radinekiyan ◽  
Mohammad Sobhani ◽  
Farzane khalili ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Biological Activity ◽  
Silk Fibroin ◽  
Agarose Hydrogel ◽  
Novel Scaffold ◽  
Fibroin Solution ◽  
Zinc Chromite

Given the important aspects of wound healing approaches, in this work, an innovative biocompatible nanobiocomposite scaffold was designed and prepared based on cross-linked lignin–agarose hydrogel, extracted silk fibroin solution, and zinc chromite (ZnCr2O4) nanoparticles.

Impact of metalloproteinase motifs on the mechanical properties of pegda hydrogels as potential biodegradable scaffolds for wound healing

Cytotherapy ◽  
2021 ◽  
Vol 23 (5) ◽  
pp. S141
Author(s):  
G.A. Bayona ◽  
V.A. Solarte-David ◽  
A.V. Pinzon-Mora ◽  
M.L. Arango-Rodriguez ◽  
S.M. Becerra-Bayona
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Biodegradable Scaffolds

RNA Sequencing Reveals the Wound Repair Mechanism of Cuyuxunxi Prescription in Surgical Patients with Anal Fistulas

2021 ◽  
Vol 24 ◽  
Author(s):  
Yin Qu ◽  
Zhijun Zhang ◽  
Yafeng Lu ◽  
De Zheng ◽  
Wei Yang
Keyword(s):  
Wound Healing ◽  
Treatment Group ◽  
Rna Sequencing ◽  
Anal Fistula ◽  
Wound Repair ◽  
Inflammatory Responses ◽  
Control Group ◽  
Surgical Wound ◽  
Anal Fistulas ◽  
Skin Development

Background: Anal fistula is one of the most common colorectal and perirectal diseases in the world. Cuyuxunxi (CYXX) prescription is an efficient herbal fumigant used to promote the surgical wound healing of anal fistulas. Objective: This study aimed to explore the underlying molecular mechanism of CYXX prescription on surgical wound healing of anal fistulas. Methods: Ten patients with anal fistula were randomized into a control group or treatment group. The wound surface of patients in the control group was rinsed by normal saline, while that in the treatment group was rinsed by CYXX prescription. The wound tissues of patients with anal fistulas seven days after the surgery were collected for hematoxylin-eosin (HE) staining and RNA sequencing. The expressions of differentially expressed genes (DEGs) were validated by real-time quantitative PCR (RT-qPCR). Results: HE staining showed that CYXX treatment reduced the infiltration of inflammatory cells. A total of 472 DEGs, including 141 up-regulated genes and 331 down-regulated genes, were identified. These genes were significantly related to skin development, xenobiotic stimulus, and inflammation. In addition, the consistency rate of RT-qPCR and sequencing results was 83.33%, which showed a high relative reliability of the sequencing results. Conclusion: CYXX prescription could improve epidermis repair and reduce inflammatory responses.

Evaluation of Surgical Wound Healing in Orthopedic Patients with Impaired Tissue Integrity According to Nursing Outcomes Classification

2018 ◽  
Vol 30 (4) ◽  
pp. 228-233 ◽  
Author(s):  
Luciana Nabinger Menna Barreto ◽  
Marcos Barragan da Silva ◽  
Bruna Engelman ◽  
Manoela Schmarczek Figueiredo ◽  
Alba Luz Rodríguez‐Acelas ◽  
...  
Keyword(s):  
Wound Healing ◽  
Surgical Wound ◽  
Tissue Integrity ◽  
Nursing Outcomes ◽  
Nursing Outcomes Classification ◽  
Orthopedic Patients

scholarly journals Duration of smoking cessation for the prevention of surgical wound healing complications

2014 ◽  
Vol 48 (1) ◽  
pp. 170-176 ◽  
Author(s):  
Barbara Vieira Cavichio ◽  
Daniele Alcalá Pompeo ◽  
Graziella Allana Serra Alves de Oliveira Oller ◽  
Lídia Aparecida Rossi
Keyword(s):  
Wound Healing ◽  
Smoking Cessation ◽  
Tobacco Use ◽  
Latin American ◽  
Scientific Evidence ◽  
Perioperative Period ◽  
Caribbean Literature ◽  
Surgical Wound ◽  
Level Of Evidence ◽  
Tobacco Use Cessation

The study aimed to find scientific evidence about the duration of preoperative smoking cessation required to reduce surgical wound healing complications. An integrative review was performed in the databases, Latin American and Caribbean Literature on Health Sciences (LILACS) and Medical Literature Analysis and Retrieval System Online (MEDLINE), from 08/17/2012 to 09/17/2012, using the keywords: tobacco use cessation and wound healing; tobacco use cessation and preoperative period; tobacco use cessation and perioperative period (LILACS) and tobacco use cessation and perioperative period; tobacco use cessation and wound healing (MEDLINE). Out of the 81 eligible studies, 12 were included. The duration of smoking cessation needed to reduce healing complications was at least four weeks (four studies with level of evidence I, three studies with level of evidence II, two studies with level of evidence IV, and one study with level of evidence VII).

Sign in / Sign up

Export Citation Format

Share Document