Relationship of Obsessive-Compulsive Disorder to Age-Related Comorbidity in Children and Adolescents With Tourette Syndrome

2012 ◽  
pp. 1 ◽  
Author(s):  
Sina Wanderer ◽  
Veit Roessner ◽  
Roger Freeman ◽  
Nathalie Bock ◽  
Aribert Rothenberger ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Obsessive Compulsive Disorder ◽  
Tourette Syndrome ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Age Related ◽  
Relationship Of

scholarly journals Responsibility Beliefs, Memory Confidence, Intolerance of Uncertainty and the Urge to Check in Childhood Obsessive-Compulsive Disorder: An Examination of Cognitive Theory

2011 ◽  
Vol 28 (3) ◽  
pp. 128-142 ◽  
Author(s):  
Lara J. Farrell ◽  
Allison M. Waters ◽  
Mark J. Boschen ◽  
Ella L. Milliner
Keyword(s):  
Children And Adolescents ◽  
Obsessive Compulsive Disorder ◽  
Cognitive Theory ◽  
Intolerance Of Uncertainty ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Age Related ◽  
Inflated Responsibility ◽  
The Impact ◽  
Memory Confidence

AbstractObjective: This study aimed to extend current research into cognitive models of obsessive–compulsive disorder (OCD) in a pediatric sample by examining the impact of perceived responsibility on memory confidence, intolerance of uncertainty (IU) and checking urge using an experimental design to manipulate perceived responsibility. It was hypothesised that the high responsibility condition would result in higher ratings of responsibility, lower memory confidence and higher IU, which would also result in higher ratings on urge to check. Moreover, it was hypothesised that adolescents would report significantly higher ratings of responsibility than children. Finally, it was hypothesised that the effect of perceived inflated responsibility on the urge to check in a high responsibility condition would be mediated by IU.Method: Twenty-seven children and adolescents diagnosed with OCD completed an experimental cognitive appraisal task (CAT) in which they heard two standardised vignettes presented in counterbalanced order; one in which participants were responsible and one in which they were not responsible for preventing harm to a friend's pet cat. Memory confidence, IU and checking urge were assessed after each scenario using Likert scales.Results: The manipulation of perceived responsibility was successful with children and adolescents rating increased responsibility in the high compared with the low responsibility scenario. There were no differences across high and low responsibility conditions, however, in ratings of memory confidence, IU or the urge to check. There were no significant age-related differences; however, there was a trend for adolescents to report higher ratings across all variables. Finally, the relationship between perceived inflated responsibility and the urge to check was not mediated by IU.Conclusions: Responsibility is not related to ratings of memory confidence, IU or the urge to check in a pediatric sample, suggesting that biases of responsibility may not be central to the formulation of childhood OCD. Results are discussed in terms of implications for cognitive formulations and cognitive approaches to treatment in pediatric OCD.

scholarly journals Obsessive-compulsive disorder in children and adolescents: epidemiology, diagnosis and management

2020 ◽  
Vol 9 (S1) ◽  
pp. S76-S93
Author(s):  
Ahsan Nazeer ◽  
Finza Latif ◽  
Aisha Mondal ◽  
Muhammad Waqar Azeem ◽  
Donald E. Greydanus
Keyword(s):  
Children And Adolescents ◽  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Diagnosis And Management

scholarly journals Disturbed Monitoring and Response Inhibition in patients with Gilles De La Tourette Syndrome and Co-Morbid Obsessive Compulsive Disorder

2003 ◽  
Vol 14 (1-2) ◽  
pp. 29-37 ◽  
Author(s):  
Sandra Verena Müller ◽  
Sönke Johannes ◽  
Berdieke Wieringa ◽  
Axel Weber ◽  
Kirsten Müller-Vahl ◽  
...  
Keyword(s):  
Executive Functions ◽  
Obsessive Compulsive Disorder ◽  
Tourette Syndrome ◽  
Response Inhibition ◽  
Error Detection ◽  
Neuropsychological Tests ◽  
Cognitive Domain ◽  
Control Group ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Objective:Fronto-striatal dysfunction has been discussed as underlying symptoms of Tourette syndrome (TS) with co-morbid Obsessive Compulsive Disorder (OCD). This suggests possible impairments of executive functions in this disorder, which were therefore targeted in the present study.Results:A comprehensive series of neuropsychological tests examining attention, memory and executive functions was performed in a group of 14 TS/OCD in co-occurrence with OCD patients and a matched control group.Results:While attentional and memory mechanisms were not altered, TS/OCS patients showed deficits in executive functions predominately in the areas of response inhibition and action monitoring.Conclusions:These findings provide further evidence for a substantial impairment of the frontal-striatal-thalamic-frontal circuit. We propose that the deficits in monitoring, error detection and response inhibition constitute the major impairment of TS/OCD patients in the cognitive domain.

Association of the CHRNA7 promoter variant −86T with Tourette syndrome and comorbid obsessive-compulsive disorder

2014 ◽  
Vol 219 (3) ◽  
pp. 710-711 ◽  
Author(s):  
Birgitte Bertelsen ◽  
Linea Melchior ◽  
Camilla Groth ◽  
Nanette Mol Debes ◽  
Liselotte Skov ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Tourette Syndrome ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Brain-derived neurotrophic factor: A genetic risk factor for obsessive-compulsive disorder and Tourette syndrome?

2006 ◽  
Vol 21 (6) ◽  
pp. 881-883 ◽  
Author(s):  
Stefanie Klaffke ◽  
Inke R. König ◽  
Fritz Poustka ◽  
Andreas Ziegler ◽  
Johannes Hebebrand ◽  
...  
Keyword(s):  
Risk Factor ◽  
Obsessive Compulsive Disorder ◽  
Tourette Syndrome ◽  
Neurotrophic Factor ◽  
Genetic Risk ◽  
Brain Derived Neurotrophic Factor ◽  
Genetic Risk Factor ◽  
Obsessive Compulsive ◽  
Compulsive Disorder
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