Autologous Pure Platelet-Rich Plasma Dermal Injections for Facial Skin Rejuvenation

2017 ◽  
Vol 43 (6) ◽  
pp. 826-835 ◽  
Author(s):  
Norma Cameli ◽  
Maria Mariano ◽  
Iole Cordone ◽  
Elva Abril ◽  
Serena Masi ◽  
...  
Keyword(s):  
Platelet Rich Plasma ◽  
Facial Skin ◽  
Skin Rejuvenation

Synergistic Effects of Autologous Platelet-Rich Plasma and Hyaluronic Acid Injections on Facial Skin Rejuvenation

2021 ◽  
Author(s):  
Barbara Hersant ◽  
Mounia SidAhmed-Mezi ◽  
Celine Aboud ◽  
Jeremy Niddam ◽  
Samuel Levy ◽  
...  
Keyword(s):  
Synergistic Effects ◽  
Platelet Rich Plasma ◽  
Post Treatment ◽  
Facial Appearance ◽  
Skin Elasticity ◽  
Facial Skin ◽  
Skin Rejuvenation ◽  
Serious Adverse Events ◽  
Autologous Platelet Rich Plasma ◽  
Cellular Matrix

Abstract Background Many therapeutic options are currently available for facial skin rejuvenation, but little evidence exists about the efficacy of combining such procedures. Objectives To assess and investigate the synergic effect of HA and a-PRP injections on facial skin rejuvenation. Methods For this randomized controlled prospective study, 93 eligible patients were enrolled and randomized into three intervention groups to undergo a series of three treatments sessions with either a-PRP, HA or Cellular Matrix-BCT-HA (PRP-HA) injected on facial cheeks. Results A total of 93 patients were included. Treatment with Cellular Matrix BCT-HA led to a very significant improvement in the overall facial appearance compared to groups treated with a-PRP and HA alone (p<0.0001). Participants treated with Cellular Matrix showed a 20%, 24% and 17% increase in FACE-Q score at 1 month, 3 months and 6 months post-treatment, respectively. For the HA group, the improvement of FACE-Q score was 12%, 11% and 6% at 1, 3- and 6-months post-treatment, respectively, while the a-PRP group showed a 9% improvement in FACE-Q score at 1 month and 11% and 8% improvement at 3- and 6-months post-treatment, respectively.Biophysical measurements showed significantly improved skin elasticity for the group Cellular BCT-HA compared to a-PRP and HA alone. No serious adverse events were reported. Conclusions Combining a-PRP and HA seems to be a promising treatment for facial rejuvenation with a very significant improvement in facial appearance and skin elasticity compared to a-PRP or HA alone.

scholarly journals Reliability and Validity of Facial Check Sheet (FCS): Checklist for Self-Satisfaction with Cosmetic Acupuncture

Medicines ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 18
Author(s):  
Hiroshi Kuge ◽  
Hidetoshi Mori ◽  
Tim Hideaki Tanaka ◽  
Ryouta Tsuji
Keyword(s):  
Reliability And Validity ◽  
Internet Survey ◽  
Age Group ◽  
Facial Skin ◽  
Moderate Correlation ◽  
Skin Rejuvenation ◽  
Facial Region ◽  
Practical Tool ◽  
Multiple Comparison Procedure ◽  
The Relationship

Background: In recent years, cosmetic acupuncture has gained popularity among individuals interested in improving their facial appearance. We have created an original facial check sheet (FCS) to obtain cosmetic acupuncture patients’ perspectives on treatment outcomes. This study examined the reliability and validity of FCS. Methods: We conducted an Internet survey on the appearance of the facial region among Japanese women. A reliability analysis was performed between each item of FCS. A multiple comparison procedure was used to determine the relationship between the age group, the FCS score, and the number of terms used in the open-ended question. Results: The most frequently stated concern was blotchiness and hyperpigmented spots (47.2%, n = 67). The FCS items showed reliability (Cronbach α = 0.871). The number of extracted terms and the FCS score showed a moderate correlation (r = 0.407; p < 0.001). There was a significant relationship between age and FCS score (p = 0.005, r2 = 0.255), which indicated that the FCS score increases with aging. Conclusions: The FCS can be used as a practical tool to evaluate facial appearances and assess satisfaction levels of patients who underwent cosmetic acupuncture or other facial skin rejuvenation procedures.

scholarly journals Platelet-Rich Plasma: Principles and Applications in Plastic Surgery

2019 ◽  
Vol 33 (03) ◽  
pp. 155-161 ◽  
Author(s):  
Amjed Abu-Ghname ◽  
Aurelia Trisliana Perdanasari ◽  
Matthew J. Davis ◽  
Edward M. Reece
Keyword(s):  
Plastic Surgery ◽  
Platelet Rich Plasma ◽  
New Technology ◽  
Clinical Applications ◽  
Great Promise ◽  
Clinical Settings ◽  
Skin Rejuvenation ◽  
Basic Principles ◽  
Reconstructive Plastic Surgery ◽  
Reconstructive Plastic

AbstractPlatelet-rich plasma (PRP) is an autogenously harvested liquid platelet concentrate extracted from a patient's peripheral blood that contains higher than baseline concentrations of growth factors and cytokines. This innovative new technology has demonstrated great promise in the field of plastic surgery, and its use has been evaluated in several clinical settings including wound healing, hair restoration, and skin rejuvenation. The goal of this article is to explain the biology behind PRP and to review the basic principles involved in its preparation. This will be followed by a discussion of some clinical applications of PRP in both aesthetic and reconstructive plastic surgery.

scholarly journals Platelet rich plasma in dermatology and cosmetology

2020 ◽  
Vol 6 (2) ◽  
pp. 288
Author(s):  
Shobhit Mohan ◽  
Lalit Mohan ◽  
Renu Sangal ◽  
Neelu Singh
Keyword(s):  
Wound Healing ◽  
Tissue Regeneration ◽  
Blood Product ◽  
Platelet Rich Plasma ◽  
Autologous Blood ◽  
Detailed Knowledge ◽  
Skin Rejuvenation ◽  
Scar Revision ◽  
Current Review

<p class="abstract">Platelet rich plasma (PRP) therapies in medicine has become increasing popular during the last decade. The interest in in the application of PRP in dermatology and cosmetology has increased recently in different applications such as alopecia, skin rejuvenation, wound healing, scar revision, and tissue regeneration. PRP is an autologous blood product obtained from the blood of the patients. The detailed knowledge about PRP should help clinicians better understand this therapy. In this view, the current review was done for a better understanding of what pathologies can be corrected with PRP.</p>

Can Activated Platelet Rich Plasma Combined with Adipose-Derived Stem Cells Be Used to Treat Skin Wrinkles?

2013 ◽  
pp. 313-329
Author(s):  
Phuc Van Pham ◽  
Loan Thi-Tung Dang ◽  
Nhung Hai Truong ◽  
Ngoc Kim Phan
Keyword(s):  
Stem Cells ◽  
Platelet Rich Plasma ◽  
Adipose Derived Stem Cells ◽  
Fibroblast Proliferation ◽  
Skin Rejuvenation ◽  
Collagen Production ◽  
Dermal Layer ◽  
Skin Wrinkles

In recent years, Platelet Rich Plasma (PRP) and Adipose-Derived Stem Cells (ADSCs) have been used separately for many clinical applications, especially skin rejuvenation. A combined injection of PRP and ADSCs could therefore be used to treat skin wrinkles. However, there are controversies and reports with conflicting results regarding the efficacy of this treatment. The authors aimed to determine the anti-wrinkle and skin rejuvenation mechanism of combined PRP and ADSCs treatment. The effects of PRP and ADSCs isolated from the same consenting donors were evaluated using in vitro and in vivo models. The in vitro effects of PRP and ADSCs on dermal fibroblast proliferation, collagen production, and inhibition of Matrix Metalloproteinase-1 (MMP-1) production were investigated using a co-culture model. Fibroblasts and ADSCs were cultured within the same dish, but in two separate cavities (using an insert plate), in the presence of the same PRP-supplemented medium. In vivo, the authors evaluated the effects of combined PRP and ADSCs on skin histochemistry, including changes in the dermal layer and collagen production in photo-aged skin (mice). They also determined the survival and differentiation of grafted ADSCs. The results show that combined PRP and ADSCs strongly stimulate in vitro fibroblast proliferation, collagen production, and inhibition of MMP-1 synthesis. Intra-dermal co-injection of PRP and ADSCs was observed to stimulate increased dermal layer thickness and collagen production compared with the untreated group. These results indicate that a combined PRP and ADSC injection can reduce wrinkles more effectively than either PRP or ADSC alone, and provide insight into the clinical use of PRP combined with ADSCs for dermal applications, particularly skin rejuvenation.

Hyperdiluted Calcium Hydroxylapatite 1:2 for Mid and Lower Facial Skin Rejuvenation: Efficacy and Safety

2020 ◽  
Vol 46 (12) ◽  
pp. e112-e117 ◽  
Author(s):  
Pier Paolo Rovatti ◽  
Giovanni Pellacani ◽  
Stefania Guida
Keyword(s):  
Efficacy And Safety ◽  
Facial Skin ◽  
Skin Rejuvenation ◽  
Calcium Hydroxylapatite
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