Pediatric reference values of carotid-femoral pulse wave velocity determined with an oscillometric device

2012 ◽  
Vol 30 (11) ◽  
pp. 2159-2167 ◽  
Author(s):  
Dagmar-Christiane Fischer ◽  
Corinna Schreiver ◽  
Mirjam Heimhalt ◽  
Anja Noerenberg ◽  
Dieter Haffner
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Oscillometric Device

scholarly journals Normal and reference values for cardiovascular magnetic resonance-based pulse wave velocity in the middle-aged general population

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Max J. van Hout ◽  
Ilona A. Dekkers ◽  
Jos J. Westenberg ◽  
Martin J. Schalij ◽  
Ralph L. Widya ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
General Population ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Disease Risk ◽  
Cardiovascular Disease Risk

Abstract Background Aortic stiffness, assessed through pulse wave velocity (PWV), is an independent predictor for cardiovascular disease risk. However, the scarce availability of normal and reference values for cardiovascular magnetic resonance imaging (CMR) based PWV is limiting clinical implementation. The aim of this study was to determine normal and reference values for CMR assessed PWV in the general population. Methods From the 2,484 participants of the Netherlands Epidemiology of Obesity (NEO) study that have available CMR-PWV data, 1,394 participants free from cardiovasculard disease, smokers or treatment for diabetes, hypertension or dyslipidaemia were selected (45–65 years, 51% female). Participants were divided into sex, age and blood pressure (BP) subgroups. Normal values were specified for participants with a BP < 130/80 mmHg and reference values for elevated BP subgroups (≥ 130/80 and < 140/90 mmHg; and ≥ 140/90 mmHg). Differences between groups were tested with independent samples t-test or ANOVA. Due to an oversampling of obese individuals in this study, PWV values are based on a weighted analysis making them representative of the general population. Results Normal mean PWV was 6.0 m/s [95% CI 5.8–6.1]. PWV increased with advancing age and BP categories (both p < 0.001). There was no difference between sex in normal PWV, however in the BP > 140/90 mmHg women had a higher PWV (p = 0.005). The interpercentile ranges were smaller for participants < 55 years old compared to participants ≥ 55 years, indicating an increasing variability of PWV with age. PWV upper limits were particularly elevated in participants ≥ 55 years old in the high blood pressure subgroups. Conclusion This study provides normal and reference values for CMR-assessed PWV per sex, age and blood pressure category in the general population.

P1539Aortic pulse wave velocity measured by an oscillometric device independently predicts all-cause mortality in a cohort of 4146 subjects

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
Z Lenkey ◽  
M Illyes ◽  
T Kahan ◽  
P Boutouyrie ◽  
S Laurent ◽  
...  
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Care Setting ◽  
Pulse Wave ◽  
Cox Regression ◽  
Aortic Pulse Wave Velocity ◽  
Oscillometric Device ◽  
All Cause Mortality ◽  
The Mean

Abstract Objectives Assessment of carotid-femoral pulse wave velocity by applanation tonometry independently predicts all-cause and cardiovascular mortality. However, there has been a need for a simpler, user-independent measurement with a validated device, that is applicable even in the primary care setting. Methods and subjects 4146 subjects (49% men) aged 35–75 years were measured in multiple centers in Hungary. Subjects visited the outpatient department of these centers on their own initiative. The measurement of aortic pulse wave velocity (PWVao) with Arteriograph was performed in addition to taking past medical history, physical examination and laboratory tests. The mean follow-up time of the study was 5.5 years. The number of events (all cause mortality) were provided by the Hungarian National Health Insurance Fund. Cox regression analyses were used to identify predictive factors for this endpoint. Results The mean age of the study population was 53 years, brachial systolic and diastolic blood pressure were 137±20 and 82±11 mmHg, and heart rate was 70±10 1/min. The mean value of SCORE was 3 in this large cohort. 410 subjects had a registered cerebro-or cardiovascular event before the measurement, the number of smokers was 656 (16%), 1974 subjects were treated with at least one anti-hypertensive drug (48%), while the number of subjects on lipid-lowering, antidiabetic or antiplatelet medication were 807 (19%), 352 (8%) and 398 (17%), respectively. There were 116 fatal events during a mean follow-up of 5.5 years. According to the Cox regression, PWVao is a significant and independent predictor of all cause-mortality and in univariate analysis, a 1.0 m/s increase in PWVao was associated with HR 1.7 [1.47–1.98; p<0.001], for this endpoint. Conclusion Aortic pulse wave velocity measured by an invasively validated, simple, oscillometric device predicted all-cause mortality in a large cohort of relatively young subjects of the general population that may improve risk stratification even in the everyday clinical practice or primary care setting.

scholarly journals Aortic Pulse Wave Velocity in Healthy Children and Adolescents: Reference Values for the Vicorder Device and Modifying Factors

2015 ◽  
Vol 28 (12) ◽  
pp. 1480-1488 ◽  
Author(s):  
Daniela Thurn ◽  
Anke Doyon ◽  
Betul Sözeri ◽  
Aysun K. Bayazit ◽  
Nur Canpolat ◽  
...  
Keyword(s):  
Pulse Wave Velocity ◽  
Children And Adolescents ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Aortic Pulse Wave Velocity ◽  
Healthy Children ◽  
Modifying Factors

scholarly journals Normal and reference values for MRI-based pulse wave velocity in the middle-aged general population

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
M.J.P Van Hout ◽  
I.A Dekkers ◽  
J.J.M Westenberg ◽  
M.J Schalij ◽  
R De Mutsert ◽  
...  
Keyword(s):  
Blood Pressure ◽  
General Population ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Funding Source ◽  
Clinical Implementation ◽  
Research Profile ◽  
Cv Disease

Abstract Background Aortic stiffness, assessed through pulse wave velocity (PWV), is an independent predictor for cardiovascular (CV) risk. However, the scarce availability of normal and reference values for magnetic resonance imaging (MRI) based PWV is limiting clinical implementation. Purpose The aim of this study was to determine normal and reference values for MRI-PWV in the general population. Methods From the 2,484 participants of the NEO study that have available MRI-PWV data, we selected 1,639 participants that were free from CV disease or treatment for diabetes, hypertension or dyslipidaemia (age range 45–65 years, 51% male). Participants were categorized by sex, age and blood pressure (BP) subgroups. Normal values were specified for healthy (&lt;130/80 mmHg) and elevated BP (≥130/80 and &lt;140/90 mmHg) and reference values for high BP (≥140/90 mmHg) subgroups. Differences between groups were tested with either an independent samples t-test or ANOVA. Results Overall mean PWV was 6.5 m/s [95% CI 6.4–6.6]. PWV increased significantly with advancing age and BP categories (both p&lt;0.001). There was no difference in PWV between men and women, however a stronger increasing trend for women above 55 years old was observed (figure). The 95% CI's were smaller for participants &lt;55 years old as compared to participants &gt;55, indicating an increasing variability of PWV with age. The elevated PWV upper limits for the higher blood pressure subgroups are particularly evident in participants above 55 years old. Conclusion This study provides normal and reference values for MRI-assessed PWV per sex, age and blood pressure category. PWV percentiles (10, 25, 50, 75 and 90th) Funding Acknowledgement Type of funding source: Public hospital(s). Main funding source(s): The NEO study is supported by the participating departments, the Division and the Board of Directors of the Leiden University Medical Centre, and by the Leiden University, Research Profile Area “Vascular and Regenerative Medicine”

scholarly journals Reference Values of Pulse Wave Velocity in Healthy Children and Teenagers

Hypertension ◽  
2010 ◽  
Vol 56 (2) ◽  
pp. 217-224 ◽  
Author(s):  
George S. Reusz ◽  
Orsolya Cseprekal ◽  
Mohamed Temmar ◽  
Éva Kis ◽  
Abdelghani Bachir Cherif ◽  
...  
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Healthy Children

scholarly journals Corrigendum to “Reference Values of Pulse Wave Velocity in Healthy People from an Urban and Rural Argentinean Population”

2015 ◽  
Vol 2015 ◽  
pp. 1-2
Author(s):  
Alejandro Díaz ◽  
Cintia Galli ◽  
Matías Tringler ◽  
Agustín Ramírez ◽  
Edmundo Ignacio Cabrera Fischer
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Healthy People

scholarly journals No significant association of serum klotho concentration with blood pressure and pulse wave velocity in a Chinese population

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Wan-Ying Liang ◽  
Li-Hong Wang ◽  
Jian-Hang Wei ◽  
Qing-Lu Li ◽  
Qi-Yan Li ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Chinese Population ◽  
Pulse Wave ◽  
Enzyme Linked Immunosorbent Assay ◽  
Oscillometric Device ◽  
Median Serum ◽  
Generalized Transfer Function

AbstractKlotho, an important anti-aging protein, may be related to elevated blood pressure (BP) and arterial stiffness. We aimed to investigate associations between the serum klotho concentration and peripheral/central BP and arterial stiffness based on the carotid–femoral pulse wave velocity (cfPWV) in a Chinese population. We invited all inhabitants aged ≥ 18 years in two Dali communities for participation. The SphygmoCor system was used to record radial arterial waveforms. Aortic waveforms were derived using a generalized transfer function. The central BP was assessed by calibrating the brachial BP, which was measured using an oscillometric device. The serum klotho concentration was measured using an enzyme-linked immunosorbent assay and logarithmically transformed. Of the 716 participants (mean age: 51.9 ± 12.6 years), 467 (65.2%) were women. The median serum klotho concentration was 381.8 pg/mL. The serum klotho concentration did not significantly differ between patients with and without hypertension (P > 0.05) and between those with and without arterial stiffness (cfPWV ≥ 10 m/s) (P > 0.05). After adjusting for confounders, the serum klotho concentration was not significantly associated with the peripheral or central BP (P > 0.05) and cfPWV (P > 0.05). Our data indicated that the serum klotho concentration was not associated with BP or cfPWV in the general Chinese population.

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