Radiotherapy- or Radical Surgery–Induced Female Sexual Morbidity in Stages IB and II Cervical Cancer

2014 ◽  
Vol 24 (4) ◽  
pp. 800-805 ◽  
Author(s):  
Yuko Harding ◽  
Takuma Ooyama ◽  
Tomoko Nakamoto ◽  
Akihiko Wakayama ◽  
Wataru Kudaka ◽  
...  

ObjectiveThe objective of this study was to evaluate the sexual function in cervical cancer survivors after radiotherapy (RT) or radical surgery (RS).MethodsThis was an observational and cross-sectional study. The Female Sexual Function Index (FSFI) self-reported questionnaires were distributed to 175 patients after RT (RT group) or RS (RS group) and 521 healthy women (control) between 2011 and 2012. Sexual functions were compared among these 3 groups.ResultsEligible 92 patients (46 in RT group, 46 in RS group) and 148 control subjects were included for analysis. There was a significant difference in median (range) FSFI total score of 5.5 (3.6–34.7) in the RT group, 18.9 (3.4–31.2) in the RS group, and 22.1 (2–34.2) in the control group (P < 0.001). The median FSFI total score in the RT group was significantly lower than that in the control group (P < 0.001). Six sexual domains (desire, arousal, lubrication, orgasm, satisfaction, pain) were all significantly affected in the RT group, and no significant differences, except pain, were observed in the RS group as compared with the control group.ConclusionsInterventions involving counseling and rehabilitation for female sexual function should be provided in cervical cancer survivors, especially after RT.

2018 ◽  
Vol 18 (2) ◽  
pp. 289-294
Author(s):  
Thalita Rodrigues Christovam Pereira ◽  
Elissa Hanayama Dottori ◽  
Flávia Maciel de Aguiar Fernandes Mendonça ◽  
Ana Carolina Sartorato Beleza

Abstract Objectives: (i) to evaluate female sexual function in remote postpartum period within Brazilian women and (ii) to compare female sexual dysfunction in relation to the mode of delivery. Methods: in this cross-sectional study, two groups of remote postpartum women, who underwent vaginal delivery (n=30) and cesarean (n=48), were studied. The sexual function of participants was assessed through an online Brazilian version of FSFI between 45 and 180 days after delivery. Data were analyzed by descriptive and inferential statistics using Fisher exact test, and Student t test. Results: based on the data of 78 women who completed the online questionnaire, 78% (n=61) showed sexual dysfunction on remote postpartum period being that the FSFI mean score for vaginal postpartum was 22.17 and for cesarean postpartum, 21.12 (p=0.443). Conclusions: the majority of remote postpartum women showed sexual dysfunction. There was no significant difference found on female sexual function between modes of delivery.


2014 ◽  
Vol 32 (1) ◽  
pp. 70-77
Author(s):  
Carla Cristina J. N. de Almeida ◽  
Paula de Oliveira Mora ◽  
Valmir Aparecido de Oliveira ◽  
Camila Aparecida Joao ◽  
Carolina Regina Joao ◽  
...  

Objective: To evaluate the presence of family breakdown factors among eutrophic and overweight/obese adolescents. Methods: Cross-sectional study of 242 students aged between 14 and 19 years old, from a public school. Each student was weighed, measured and answered a questionnaire with closed questions addressing the presence of family breakdown factors. The adolescents were divided in two groups: euthophic and overweight/obese. The answers of both groups were compared by Fisher's exact and Mann-Whitney tests. Results: There was no statistically significant difference in the prevalence of the studied factors between the two groups. Comparing the number of positive answers (presence of family breakdown factors) and negative ones (absence of family breakdown factors), no difference was observed between the groups. Conclusions: The inclusion of a control group showed that factors of family breakdown, usually identified as associated with obesity in adolescents, may also be present in eutrophic adolescents.


2020 ◽  
pp. 20-23
Author(s):  
Sneha Upadhyay ◽  
Jyoti Bhavthankar ◽  
Mandakini Mandale ◽  
Nivedita Kaorey

Background: Asthma and its medications have been linked to oral diseases in asthmatic children. Aim: Assessment of the dental caries status, salivary Streptococcus mutans count and S. mutans colony score in children receiving inhaled anti asthmatic medications and their comparison in healthy children Material and Method: A cross-sectional study was performed on 40 asthmatic children and 40 healthy children in the age group of 6-14 years. DMFT/deft indices were calculated and saliva samples were collected. Diluted saliva was inoculated on MSB agar plates. S. mutans count and colony score were analysed after 24-48 hours of inoculation. Results: Statistically significant difference was observed in the mean DMFT/deft index, salivary S. mutans load and S. mutans colony score in children of the asthmatic group and control group. Conclusion: Prevalence of dental caries and cariogenic bacteria is higher in asthmatic children.


Medicina ◽  
2020 ◽  
Vol 56 (3) ◽  
pp. 142
Author(s):  
Osama Y. Al-Dirbashi ◽  
Charu Sharma ◽  
Nahid Al Dahouri ◽  
Anas Al Aidaros ◽  
Shamma Al-Muhairi ◽  
...  

Background and objectives: Although laparoscopic sleeve gastrectomy (LSG) is effective for obesity management, postoperative vitamin B12 (B12) deficiency is of major concern. In this cross-sectional study, we assessed the levels of B12 and its related functional biomarkers, namely, total homocysteine (tHcy), methylmalonic acid (MMA), folate, methylcitric acid (MCA), and hemoglobin (Hb), in one-year postoperative LSG patients and matched controls. Materials and Methods: Plasma B12, tHcy, MMA, folate, and MCA were measured in matched controls (n = 66) and patients (n = 71) using validated liquid chromatography-tandem mass spectrometry techniques and protocols in the United Arab Emirates (UAE). Results: The median B12 concentration in patients (177 pmol/L) was significantly lower (p < 0.001) than in the controls (334.7 pmol/L). The tHcy and MMA levels were significantly increased (p < 0.001 and p = 0.011, respectively) and folate levels were significantly decreased (p = 0.001) in the LSG patients compared to the controls. Interestingly, no significant difference in MCA levels were observed between the two groups. The levels of tHcy and MMA were concomitantly increased with the decreased folate levels in postoperative LSG patients when compared with the controls. The Hb levels were significantly lower in males and females in the patient group compared with those in the control group, respectively (p = 0.005 and p = 0.043). Conclusions: This is the first report of serum levels of B12 and its functional biomarkers in postoperative LSG patients among a local population from the UAE. Our findings revealed significant alterations of the B12 biomarkers, total B12, MMA, and tHcy in one-year postoperative LSG patients.


2020 ◽  
Vol 114 (3) ◽  
pp. e466
Author(s):  
Ahmed M. Abbas ◽  
Mennatallah Mohamed Samir ◽  
Reham Maher Abdel-Gaber ◽  
Emad Eldien Kamal Ali

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Anna Różańska-Walędziak ◽  
Paweł Bartnik ◽  
Joanna Kacperczyk-Bartnik ◽  
Maciej Walędziak ◽  
Andrzej Kwiatkowski ◽  
...  

2018 ◽  
Vol 57 (6) ◽  
pp. 681-687 ◽  
Author(s):  
Mohammed A Farhan ◽  
Ahmed M Moharram ◽  
Tareq Salah ◽  
Omar M Shaaban

AbstractThe current study aims to compare between the types of yeasts that cause vulvovaginal candidiasis (VVC) in women using corticosteroid medication compared to nonusers and estimate their sensitivity to available commercial antifungal agents. In a descriptive analytical cross-sectional study, we recruited 41 chronic corticosteroid users diagnosed clinically to have VVC from Women's Health Hospital, Assiut University, Egypt. Forty-seven age-matched women with VVC were recruited as a control group. Full history and clinical examination were performed. Vaginal sterile swab obtained from the vagina of each participant was subjected to direct Gram-stained smear examination as well as a culture on Sabouraud's glucose agar and HiCrome Candida agar. Further identification of the isolates was done using traditional methods. Fifty out of 88 samples (56.8%) were positive in culture including 25 samples (61%) from corticosteroid users group and 25 (53.2%) from noncorticosteroid users with no statistically significant difference (P = .302). The chronic corticosteroid users had more incidence of recurrent VVC as compared to nonusers (65.9% vs 40.4%, respectively) (P = .015). There was a significantly higher rate of non-Candida albicans (NCA) infections in corticosteroid users compared with nonusers (48% vs 20%, respectively) (P = .036). A higher significant difference in resistance of the isolates against clotrimazole (P = .003) and ketoconazole (P = .017) was demonstrated in corticosteroid users compared to nonusers. Thus, chronic corticosteroid use causes frequent attacks of VVC and increases the frequency of infection by NCA strains. Also, it increases resistance to common antifungal agents especially azole group.


2020 ◽  
Vol 30 (2) ◽  
pp. 27-31 ◽  
Author(s):  
Mohammad Shamsul Ahsan ◽  
Shahjada Selim ◽  
Srijony Ahmed ◽  
Rubaiya Ali ◽  
Hosnea Ara ◽  
...  

Talks regarding sexual problems are not encouraging in Bangladesh and sufferers are in grave situation as they are not sure regarding whom to approach and how to start. It was aimed to see the presenting patterns of female sexual dysfunctions (FSD) and co-morbidities among the patients attending at different outpatient departments (OPD) at Bangabandhu Sheikh Mujib Medical University (BSMMU). This descriptive cross sectional study was conducted among 173 female patients attending at gynecology, endocrinology and psychiatry OPD, BSMMU. Sample was taken by convenient sampling within the period of October 2015 to December 2016. Data were collected through face-to-face interview with Female Sexual Function Index (FSFI) questionnaire. The results showed that, most (95.95%) of the patients were in the reproductive age group. Majority of the patients (32.95%) were in 26-30 years age group and 24.85% were in 18-25 years age group. Majority (77.5%) belonged to home maker occupational class where 12.7% was service-holder. Fifty six percent of the respondents were found to have sexual dysfunctions and 38.15% patients had endocrinological co-morbidities, 37.57% had gynecological co- morbidities and 33.53% had psychiatric co-morbidities. Positive openness in sexual health is required for the betterment of both treatment and diagnosis of sexual disorders. Specialized service center focusing the different groups is needed to deal with sexual health in a developing country like Bangladesh. Bang J Psychiatry December 2016; 30(2): 27-31


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