A mixed-methods study of coping and depression in adolescent girls with polycystic ovary syndrome

BackgroundPolycystic ovary syndrome (PCOS) is a common lifelong metabolic condition with serious associated comorbidities. Evidence points to a delay in diagnosis and inconsistency in the information provided to women with PCOS.AimTo capture women’s experiences of how PCOS is diagnosed and managed in UK general practice.Design and settingThis was a mixed-methods study with an online questionnaire survey and semi-structured telephone interviews with a subset of responders.MethodAn online survey to elicit women’s experiences of general practice PCOS care was promoted by charities and BBC Radio Leicester. The survey was accessible online between January 2018 and November 2018. A subset of responders undertook a semi-structured telephone interview to provide more in-depth data.ResultsA total of 323 women completed the survey (average age 35.4 years) and semi-structured interviews were conducted with 11 women. There were five key themes identified through the survey responses. Participants described a variable lag time from presentation to PCOS diagnosis, with a median of 6–12 months. Many had experienced mental health problems associated with their PCOS symptoms, but had not discussed these with the GP. Many were unable to recall any discussion about associated comorbidities with the GP. Some differences were identified between the experiences of women from white British backgrounds and those from other ethnic backgrounds.ConclusionFrom the experiences of the women in this study, it appears that PCOS in general practice is not viewed as a long-term condition with an increased risk of comorbidities including mental health problems. Further research should explore GPs’ awareness of comorbidities and the differences in PCOS care experienced by women from different ethnic backgrounds.

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A comprehensive mental health care program for women with polycystic ovary syndrome: protocol for a mixed methods study

Reproductive Health ◽

10.1186/s12978-018-0488-5 ◽

2018 ◽

Vol 15 (1) ◽

Cited By ~ 2

Author(s):

Fatemeh ZareMobini ◽

Ashraf Kazemi ◽

Ziba Farajzadegan

Keyword(s):

Mental Health ◽

Health Care ◽

Mixed Methods ◽

Polycystic Ovary Syndrome ◽

Mental Health Care ◽

Polycystic Ovary ◽

Care Program ◽

Mixed Methods Study ◽

Ovary Syndrome ◽

Health Care Program

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Ovarian imaging by magnetic resonance in obese adolescent girls with polycystic ovary syndrome: a pilot study

Fertility and Sterility ◽

10.1016/j.fertnstert.2005.04.039 ◽

2005 ◽

Vol 84 (4) ◽

pp. 985-995 ◽

Cited By ~ 36

Author(s):

R YOO ◽

C SIRLIN ◽

M GOTTSCHALK ◽

R CHANG

Keyword(s):

Pilot Study ◽

Magnetic Resonance ◽

Polycystic Ovary Syndrome ◽

Adolescent Girls ◽

Polycystic Ovary ◽

Ovary Syndrome ◽

Obese Adolescent

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Early Metabolic and Endocrine Perturbations in First-Degree Relative Adolescent Girls of Polycystic Ovary Syndrome Women

10.1210/endo-meetings.2011.part2.p32.p2-239 ◽

2011 ◽

pp. P2-239-P2-239

Author(s):

Andreanne Trottier ◽

Marie-Claude Battista ◽

Judith Simoneau-Roy ◽

Andre Carpentier ◽

David H Geller ◽

...

Keyword(s):

Polycystic Ovary Syndrome ◽

Adolescent Girls ◽

Polycystic Ovary ◽

Degree Relative ◽

Ovary Syndrome

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The Impact of Proband Glucose Tolerance Status on Body Mass Index (BMI) and Adiposity in Adolescent Girls at High Risk for Polycystic Ovary Syndrome (PCOS)

10.1210/endo-meetings.2010.part1.p7.p1-341 ◽

2010 ◽

pp. P1-341-P1-341

Author(s):

DH Geller ◽

S Ten ◽

R Mathew ◽

SE Oberfield ◽

MI Hernandez ◽

...

Keyword(s):

Body Mass Index ◽

High Risk ◽

Polycystic Ovary Syndrome ◽

Glucose Tolerance ◽

Body Mass ◽

Adolescent Girls ◽

Polycystic Ovary ◽

Ovary Syndrome ◽

Glucose Tolerance Status ◽

The Impact

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Effective treatment of different types of polycystic ovary syndrome in adolescent girls

Medical Council ◽

10.21518/2079-701x-2021-21-2-56-60 ◽

2022 ◽

pp. 56-60

Author(s):

E. V. Uvarova ◽

E. P. Khashchenko ◽

S. O. Kyurdzidi

Keyword(s):

Polycystic Ovary Syndrome ◽

Effective Treatment ◽

Adolescent Girls ◽

Treatment Strategy ◽

Polycystic Ovary ◽

Young Female ◽

Diagnosis And Treatment ◽

Medical Community ◽

Ovary Syndrome ◽

Female Patients

This review is addressing an urgent problem of diagnosis and treatment strategy of polycystic ovary syndrome in adolescent girls. We analysed data from modern literary publications on the epidemiology and classification of the disease, as well as the adaptation of general principles for the management of young female patients tailored to their age peculiarities. The effective treatment strategies for adolescent girls with PCOS depending on its type are presented. Today there are several contradictions associated with both the diagnosis and treatment of the disease in the medical community. Thus, the use of the well-known Rotterdam criteria makes it difficult to diagnose PCOS in adolescent girls, since the criteria do not take into account characteristic changes that occur during puberty. Such manifestations as acne, hirsutism, menstrual irregularities, high androgen levels and morphology of polycystic ovaries on pelvic ultrasound imaging should be assessed with due account for age, puberty, hormonal balance with an assessment of the ratio of LH (luteinizing hormone)/FSH (follicle-stimulating hormone) and Free Androgen Index. There is no consensus in the medical community regarding the treatment strategy for PCOS. International communities have identified two main goals in the management of patients: normalization of menstrual function and improvement of the patients’ quality of life by preventing clinical symptoms of hyperandrogenism, and metabolic disorders of hyperplastic processes in target organs.Our analysis of objective scientific data showed that modern monophasic combined oral contraceptives (COCs) supplemented by of a folate component should be used to treat young female patients with PCOS, hyperandrogenism and psychosomatic disorders.

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Obesity, hormonal and metabolic abnormalities in adolescent girls with polycystic ovary syndrome

Orvosi Hetilap ◽

10.1556/oh.2013.29669 ◽

2013 ◽

Vol 154 (31) ◽

pp. 1226-1234

Author(s):

László Ságodi ◽

Béla Lombay ◽

Ildikó Vámosi ◽

László Barkai

Keyword(s):

Insulin Resistance ◽

Metabolic Syndrome ◽

Body Mass Index ◽

Birth Weight ◽

Low Birth Weight ◽

Polycystic Ovary Syndrome ◽

Adolescent Girls ◽

Polycystic Ovary ◽

Metabolic Abnormalities ◽

Ovary Syndrome

Introduction: Polycystic ovary syndrome is associated with metabolic abnormalities, such as dyslipidemia, obesity, glucose intolerance, which are also components of the metabolic syndrome. Central obesity and insulin resistance appear to play an important role in the pathogenesis of polycystic ovary syndrome, perhaps via subsequent steroidogenic dysregulation. Aim: The aim of the authors was to assess metabolic and hormonal abnormalities in adolescent girls with polycystic ovary syndrome. Method: The study included 52 adolescents diagnosed with polycystic ovary syndrome based on the Rotterdam criteria. Anthropometric, hormonal and metabolic parameters were evaluated among all subjects. 20 healthy, age-matched, non-obese, regularly menstruating girls were used as controls. Of the 52 patients, 15 patients were born with low-birth-weight and 37 patients were born with normal birth weight. Oral glucose tolerance test was performed in all patients and controls. The age of patients was 16.8±3.1 years, and the age of controls was 16.95±2.1 years. Results: Among patients with polycystic ovary syndrome the prevalence of overweight and obesity was 35% (n = 18), while impaired fasting glucose occurred in one patient, impaired glucose tolerance in 8 patients, insulin resistance in 25 patients and metabolic syndrome in 12 patients. Serum triglyceride levels in patients and controls were 1.4±0.8 and 0.9±0.3 mmol/l, respectively (p<0.05), while fasting blood glucose, total cholesterol, HDL and LDL cholesterol were not different in the two groups. Metabolic abnormalities and obesity were more severe and more frequent in patients with low-birth-weight compared to those born with normal weight. There was a negative correlation between birth weight and body mass index SDS values and a positive correlation between fasting insulin levels and body mass index SDS (r = 0.37) in patients born with low-birth-weight. Conclusions: Abnormal glucose metabolism is frequently present in adolescents with polycystic ovary syndrome. It is possible that early diagnosis of polycystic ovary syndrome in adolescences may prevent some of the long-term complications associated with this syndrome. Orv. Hetil., 2013, 154, 1226–1234.

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