scholarly journals The relationship of MicroRNA-21 and plaque stability in acute coronary syndrome

Medicine ◽  
2019 ◽  
Vol 98 (47) ◽  
pp. e18049
Author(s):  
Wangwei He ◽  
Liyuan Zhu ◽  
Yu Huang ◽  
Yinfen Zhang ◽  
Weimin Shen ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Plaque Stability ◽  
Coronary Syndrome ◽  
Relationship Of ◽  
The Relationship

Association of Serum Cholesterol Ester Transfer Protein Levels with Taq IB Polymorphism in Acute Coronary Syndrome

2019 ◽  
Author(s):  
Noha N Amer ◽  
Gamal M Shaaban
Keyword(s):  
Acute Coronary Syndrome ◽  
High Serum ◽  
Enzyme Linked Immunosorbent Assay ◽  
Protein Levels ◽  
Transfer Protein ◽  
Coronary Syndrome ◽  
Healthy Control ◽  
Serum Cholesterol Ester ◽  
Relationship Of ◽  
The Relationship

Abstract Information on the relationship between circulating cholesteryl ester transfer protein (CETP) levels and coronary heart disease (CHD) incidence (and also, therefore, acute coronary syndrome [ACS]) is conflicting. Many studies have been published concerning this relationship, most of which have incompatible results. In our study, we aimed to determine serum CETP levels in subject individuals with ACS and healthy control individuals, and the association of those levels with Taq IB polymorphism. The current study was conducted with 62 hospitalized patients who had been diagnosed with ACS and 26 controls. All subjects were selected from a previous study of which we are among the coauthors. Serum CETP levels were determined by quantitative enzyme-linked immunosorbent assay (ELISA). The mean serum CETP levels in all patients were significantly higher than those in controls. CETP TaqIB polymorphism affected serum CETP levels, with higher serum CETP for the GA genotype in both groups than in other genotypes. Although the AA genotype showed higher CETP levels than the GG genotype in patients with ACS, the GG showed higher CETP than the AA in healthy controls. Our results support an association between high serum CETP and ACS incidence. Our study helped address some of the controversies regarding the relationship of serum CETP mass to atherosclerosis, in addition to the association of ACS occurrence with circulating CETP levels.

Impact of Pharmacist Intervention to Increase Compliance With Guideline-Directed Statin Therapy During an Acute Coronary Syndrome Hospitalization

2017 ◽  
Vol 51 (5) ◽  
pp. 394-400 ◽  
Author(s):  
Robert K. Tunney ◽  
Daniel C. Johnson ◽  
Li Wang ◽  
Zachary L. Cox
Keyword(s):  
Acute Coronary Syndrome ◽  
Statin Therapy ◽  
Pharmacist Intervention ◽  
Dose Selection ◽  
Coronary Syndrome ◽  
Pilot Programs ◽  
Statin Dose ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

Background: Despite evidence on poor adherence to guideline-directed statin therapy (GDST) following an acute coronary syndrome (ACS), little information has been published on pharmacist-led statin pilot programs for secondary prevention. Objective: We sought to evaluate the impact of a pharmacist intervention (PI) on GDST during an ACS hospitalization. Methods: A historical control (HC) group consisting of 125 ACS hospitalizations was retrospectively identified, with prospective data of 113 patients captured over 6 months in the PI group. The primary outcome of GDST was defined according to 2013 clinical guidelines and evaluated in all 238 qualifying patients. Secondary outcomes included number of interventions and use of logistic regression to investigate the relationship of ACS subtype with statin dose. Results: On admission, GDST was ordered in 62.5% of the HC and 75.9% of the PI group. At discharge, the PI group had a higher rate of GDST relative to HC among all patients (86.7 % vs 77.4%, P = 0.06), and after exclusion of contraindications (84.8% vs 74.5%; P = 0.1), 10 patients required PI, accounting for an increase in GDST of 5.3%. Statin dose selection did not differ by ACS subtype (odds ratio = 0.79; 95% CI = 0.0.29-2.17; P = 0.18). Conclusion: PI did not significantly increase GDST. Increased compliance rates measured were primarily driven by higher baseline adherence and guideline incorporation over time.

scholarly journals e0283 Research on the relationship of anxiety symptoms to the quality of life in patients with acute coronary syndrome

Heart ◽  
2010 ◽  
Vol 96 (Suppl 3) ◽  
pp. A89-A89 ◽  
Author(s):  
L. Guanghui ◽  
M. Wenlin ◽  
W. Xianzheng ◽  
Z. Chenting ◽  
P. Juping ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Acute Coronary Syndrome ◽  
Anxiety Symptoms ◽  
Coronary Syndrome ◽  
Relationship Of ◽  
The Relationship

The relationship between phobic anxiety and 2-year readmission after Acute Coronary Syndrome: What is the role of heart rate variability?

2019 ◽  
Vol 247 ◽  
pp. 73-80 ◽  
Author(s):  
Adrienne O'Neil ◽  
C. Barr Taylor ◽  
David L. Hare ◽  
Emma Thomas ◽  
Samia R. Toukhsati ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Acute Coronary Syndrome ◽  
Coronary Syndrome ◽  
Phobic Anxiety ◽  
The Relationship

scholarly journals Takotsubo Cardiomyopathy and Psychiatric Illness: Redefining the Relationship

2016 ◽  
Vol 5 ◽  
Author(s):  
Hannah Masoud
Keyword(s):  
Emergency Department ◽  
Takotsubo Cardiomyopathy ◽  
Psychiatric Illness ◽  
Panic Attacks ◽  
Shortness Of Breath ◽  
Model Of Care ◽  
Coronary Syndrome ◽  
Relationship Of ◽  
Anxiety Depression ◽  
The Relationship

Physicians who encounter patients in the emergency department with chest pain, palpitations, or shortness of breath may often find it difficult to differentiate diagnosis of panic attacks from acute coronary syndrome or Takotsubo Cardiomyopathy. Redefining and understanding the pathophysiological relationship of psychiatric illness including anxiety, depression, or panic attacks and Takotsubo Cardiomyopathy may help clinicians implement a more effective and beneficial model of care for this affliction that is being found to be increasingly more common in today’s age.

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