scholarly journals Retrospective study of clinical and pathologic features of pulmonary papillary adenoma

Medicine ◽  
2020 ◽  
Vol 99 (44) ◽  
pp. e23066
Author(s):  
Pengcheng Zhou ◽  
Wei Yu ◽  
Li Wang ◽  
Qianming Xia ◽  
Keling Chen
Keyword(s):  
Retrospective Study ◽  
Papillary Adenoma ◽  
Pathologic Features ◽  
Pulmonary Papillary Adenoma

scholarly journals Cytological Features of Pulmonary Papillary Adenoma with Malignant Transformation and Literature Review

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Xingen Hu ◽  
Yi Chen ◽  
Guoqing Ru ◽  
Lili Yu
Keyword(s):  
Malignant Transformation ◽  
Alveolar Epithelium ◽  
Middle Lobe ◽  
Papillary Adenoma ◽  
Tissue Mass ◽  
Napsin A ◽  
Treatment Measures ◽  
Cytological Features ◽  
The Right ◽  
Pulmonary Papillary Adenoma

Papillary adenoma of the lung is a rather rare tumor. We will present a case of papillary adenoma in the lung with malignant transformation in a 65-year-old male patient. A high dense soft tissue mass was detected in the lateral segment of the right middle lobe by CT examination. Cytologically, the tumor contained the benign cells similar to normal alveolar epithelium and the malignant cells which were significantly enlarged and irregular, crowded, or overlapping. Immunohistochemical staining showed that the epithelial cells were diffusely positive for TTF-1, napsin-A, and CK7, but were negative for p63, p40, CK5/6, CgA, Syn, CD56, and TG. The Ki67 index was about 5%. All of these evidences indicated that it was a case of papillary adenoma with malignant transformation. Thus, it should be noted that more active treatment measures should be taken to treat pulmonary papillary adenoma.

Cytomorphologic findings and differential diagnosis of pulmonary papillary adenoma: A case report and literature review

2016 ◽  
Vol 44 (6) ◽  
pp. 543-547 ◽  
Author(s):  
Amy Frey ◽  
Houda Alatassi ◽  
Tanya Ann Wiese ◽  
Mostafa Fraig ◽  
Xiu Yang
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Literature Review ◽  
Papillary Adenoma ◽  
Pulmonary Papillary Adenoma

Gene profiling of tumor tissue in the diagnosis of patients with carcinoma of unknown primary site (CUP): Evaluation of the Veridex 10-gene molecular assay

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 21109-21109
Author(s):  
J. D. Hainsworth ◽  
D. Talantov ◽  
T. Jatkoe ◽  
C. Meng ◽  
J. Baden ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Retrospective Study ◽  
Specific Treatment ◽  
Primary Site ◽  
Ffpe Tissue ◽  
Response To Treatment ◽  
Unknown Primary ◽  
Molecular Assay ◽  
Gene Markers ◽  
Pathologic Features

21109 Background: Standard treatment for most patients with CUP involves empiric chemotherapy. Since specific treatment now exists for most types of advanced carcinoma, precise identification of the primary site could lead to improved therapy. Veridex developed an optimized set of 10 gene markers, for a qRTPCR assay to identify tissue of origin of metastatic carcinoma in formalin-fixed, paraffin-embedded (FFPE) tissue samples (J Mol Diagn 8:320, 2006). The assay includes markers for 6 primary sites: lung, pancreas, colon, breast, ovary, and prostate. In this retrospective study, we evaluated the Veridex assay in patients with CUP. Methods: We obtained FFPE tissue from diagnostic biopsies on 69 CUP patients previously enrolled in empiric chemotherapy studies. The Veridex assay was performed as previously described. Assay results were correlated with clinical features, pathologic features, and response to treatment. Results: The Veridex assay yielded provisional diagnoses in 42 of 69 patients (61%): lung (15), pancreas (11), colon (12 ), ovary (4), breast (0), and prostate, (0 ). Most patients with diagnoses of lung and pancreas cancer had clinical and pathologic features compatible with these diagnoses; response rates to empiric chemotherapy (usually taxane/platinum-based) in patients with these diagnoses were 29% and 9%, respectively. The 12 patients with colon cancer diagnoses had predominantly intra-abdominal metastases (liver, peritoneum); response rate to therapy (usually taxane/platinum- based) was low (8%). The 4 patients with ovarian cancer had atypical clinical and pathologic features, and only 1 of 4 had PR to first-line taxane/platinum therapy. Conclusions: In this retrospective study, the Veridex 10-gene molecular assay was feasible and provided provisional diagnoses in a majority of patients with CUP. The diagnoses made using this assay (except ovarian cancer) were compatible with clinicopathologic features. The efficacy of cancer-specific treatment in patients diagnosed by this assay will be evaluated in prospective studies. No significant financial relationships to disclose.

Synchronous detection of a pulmonary papillary adenoma and lung metastases in a patient with osteosarcoma in relapse

2002 ◽  
Vol 38 (2) ◽  
pp. 125-127 ◽  
Author(s):  
Andrea Neusuess ◽  
Alexander Claviez ◽  
Thomas Schroeter ◽  
Dieter Harms ◽  
Meinolf Suttorp
Keyword(s):  
Lung Metastases ◽  
Papillary Adenoma ◽  
Synchronous Detection ◽  
Pulmonary Papillary Adenoma

scholarly journals Clinicopathological Features and Treatment Outcomes in Parotid Malignancies at Ocean Road Cancer Institute, Dar-es-Salaam, Tanzania

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 192s-192s
Author(s):  
A. Adatia
Keyword(s):  
Overall Survival ◽  
Retrospective Study ◽  
Parotid Gland ◽  
Treatment Outcomes ◽  
Salivary Glands ◽  
Dar Es Salaam ◽  
Treatment Modalities ◽  
Curative Intent ◽  
Geographical Variations ◽  
Pathologic Features

Background: Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes. Tumors of the salivary glands form one of the most heterogeneous groups of oncological pathology. Head and neck tumors represent ∼5% of human neoplasms, and out of these, salivary gland neoplasms constitute 10%. Aim: The challenges faced for parotid gland malignancy are numerous and these factors determine the treatment modality, prognosis and outcome, overall survival, sociodemographic features affecting Tanzanian residents and there is very little knowledge on clinicopathological aspects of parotid gland malignancies diagnosed at a tertiary health center and this study can compare the findings with epidemiologic data from different geographic locations. Methods: A Retrospective study design was used among all patients who had been diagnosed and confirmed histologically with malignant Parotid tumor referred to and treated at Ocean Road Cancer Institute (ORCI) from January 2009-December 2016. Analysis of this retrospective study determined the sociodemographic factors, clinico-pathologic features, treatment outcomes of surgery, radiotherapy, chemotherapy and assessment of 2 years overall survival of parotid malignancies from January 2009 to December 2014. The study was conducted at ORCI in Dar es Salaam. Results: Out of 94 patients with histologically confirmed parotid gland malignancy, more males were affected compared with females with the ratio of 1.18:1 and the mean SD age of patients was 51.9 years. Adenocarcinoma was the most common malignant tumor n = 37 (40%) followed by squamous cell carcinoma n = 18 (19.1%) and the left parotid gland being the most affected site. 44 cases (46.8%) had pathologic grading, grade IV accounting for majority of the grades (27.3%). Stage IV was presented the most n=72 (76.5%) and 8.5% presented with metastasis at diagnosis. 31% of patients were subjected to surgery while 69.1% were deemed to be unfit for surgery due to advanced disease. Radiotherapy was received by n = 82 (95.2%) with 13 patients (14%) subjected to curative intent and 69 patients (86%) subjected to palliative intent. 2 year overall survival for the curative cohort from 2009-2014 is 23% and 11% for the palliative arm. The 2 year overall survival of parotid gland malignancy treated at ORCI is 12%. Conclusion: Clinico-pathologic presentation of parotid gland malignancy seen in this study differs from other studies probably due to geographical variations. More males are affected than women, especially in the middle ages. Adenocarcinoma was the most frequent histology. Two years overall survival from 2009 to 2014 was 12%. Late stage presentation was seen as a problem that needs to addressed to maximize the effectiveness of the treatment, and improve the overall survival. Treatment modalities need to be standardized across health facilities in Tanzania.

scholarly journals Pulmonary papillary adenoma presenting in central portion: a case report

2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Xu-Yong Lin ◽  
Qiang Han ◽  
En-Hua Wang ◽  
Yong Zhang
Keyword(s):  
Case Report ◽  
Papillary Adenoma ◽  
Central Portion ◽  
Pulmonary Papillary Adenoma

Cytologic Characteristics of Pulmonary Papillary Adenoma

2004 ◽  
Vol 48 (2) ◽  
pp. 243-248 ◽  
Author(s):  
Yuko Minami ◽  
Yukio Morishita ◽  
Tatsuo Yamamoto ◽  
Tatsuo Iijima ◽  
Masakatsu Fukasawa ◽  
...  
Keyword(s):  
Papillary Adenoma ◽  
Pulmonary Papillary Adenoma

A Rare Benign Pulmonary Neoplasm: A Case Report of Benign Pulmonary Papillary Adenoma

CHEST Journal ◽  
2017 ◽  
Vol 152 (4) ◽  
pp. A713
Author(s):  
Anna Kyu-K Khaing Chen ◽  
Michael Ayers ◽  
Ronald Evans
Keyword(s):  
Case Report ◽  
Papillary Adenoma ◽  
Pulmonary Neoplasm ◽  
Pulmonary Papillary Adenoma

Epidemiologic, clinical, and pathologic features of lymphomas at the Peruvian hospital: Hospital Nacional Cayetano Heredia.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e12041-e12041
Author(s):  
Juan Padilla ◽  
Diego Venegas ◽  
Miro Rodriguez ◽  
Jaime Caceres ◽  
Jaime Cok ◽  
...  
Keyword(s):  
Weight Loss ◽  
Retrospective Study ◽  
T Cell ◽  
Cell Lymphoma ◽  
Clinical Stage ◽  
Male And Female ◽  
Non Hodgkin Lymphoma ◽  
Pathologic Features ◽  
The Mean ◽  
Common Histological Type

e12041 Background: During the decade 70’ to 90’ incidence of lymphomas in Lima, Peru increased from 3.4 to 7.5 per 100 000 females and from 6 to 8.3 per 100 000 males. We describe epidemiological, clinical and pathologic features of patients with lymphoma diagnosed at the Hospital Nacional Cayetano Heredia (HNCH), center of reference of Lima north. Methods: Retrospective study of 433 patients with lymphoma diagnosed from 1998 to 2008 at the HNCH. Results: The mean age was 44.8 years (range 1 to 93 years), the ratio was 1.5:1 for male and female respectively, 85.9% were Non Hodgkin Lymphoma (LNH). In Hodgkin diseases’ patients the mean age was 34 years and ratio male: female was 2:1; whereas, in NHL, the average age was 45.9 years and ratio male: female was 1.4:1. The more frequently symptoms were weight loss (40.5%) and lymphadenopathy (36.7%). The 55.08% were clinical stage I-II. The most frequent location was nodal (55.1%). More frequently extra nodal locations were: gastrointestinal (15.2%) and skin (10.8%). In NHL, the immunophenotype B were: B (57.8%), T (19.6%) and not determined ( 22.6%). The most common histological type was large diffuse cells lymphoma (35.8%). T-cell lymphoma adults occurs in 6.9% of cases, follicular in 4.7% and anaplastic in 4.7%.According to RECIST 1,1: 78.12% had remission completed and parcial. In Hodgkin’s disease’s treatment with ABVD was 90.97% of responses complete and parcial. During this period 23.45% of patients reported died Conclusions: Our patients with lymphoma retain the same general characteristics of the worldwide. ATLL had prevalence high relative to others series

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