scholarly journals Adherence to antihypertensive medications among adult hypertensive patients attending chronic follow-up units of Dessie Referral Hospital, Northeastern Ethiopia

Medicine ◽  
2021 ◽  
Vol 100 (31) ◽  
pp. e26818
Author(s):  
Atsedemariam Andualem ◽  
Tiliksew Liknaw ◽  
Afework Edmealem ◽  
Mihretie Gedefaw
2019 ◽  
Vol 8 ◽  
pp. 204800401989275
Author(s):  
Atsede Getenet ◽  
Mulugeta Tesfa ◽  
Aster Ferede ◽  
Yalew Molla

Introduction Hypertension is a global challenge which accounts for high morbidity and mortality rates in the world. The availability of effective anti-hypertensive medications does not result in a good outcome in controlling blood pressure which points towards poor adherence. Thus, this study was conducted to assess the determinants of adherence to anti-hypertensive medication among hypertensive patients on follow-up in Hawassa Referral Hospital. Methods Institution-based case–control study was conducted on a sample of 289 clients from February to May 2018. Census was conducted on 1600 clients to select cases and controls. Then, systematic random sampling was used to select study subjects, and adherence was measured by Morisky medication adherence scale. The associations of variables were analyzed using bivariable followed by multivariable logistic regression analyses. Results The respondent’s adherence to medication was found to be 67% as measured by Morisky medication adherence scale. The multivariate logistic regression analysis showed that medication adherence was found to be better in younger age (<45) (AOR = 3.8), clients living in urban areas (AOR = 6.84), those clients who had good knowledge (AOR = 3.13), those with no co-morbidities (AOR = 3.14) and patients who controlled their blood pressure (<140/90) (AOR = 2.35). Conclusions The rate of medication adherence was found to be low, and hence educational interventions focusing on factors promoting adherence and patients’ health support should be implemented.


2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Addisu Dabi Wake ◽  
Techane Sisay Tuji ◽  
Addisu Tadesse Sime ◽  
Mekuria Tesfaye Mekonnin ◽  
Taju Mohamed Taji ◽  
...  

Background. Hypertension is one of the most common noncommunicable diseases affecting several individuals globally. However, the level of nonadherence to self-care practices, antihypertensive medications, and associated factors among hypertensive patients in a follow-up clinic at Asella Referral and Teaching Hospital is unknown. Objective. To assess the level of nonadherence to self-care practices, antihypertensive medications, and associated factors among hypertensive patients in a follow-up clinic at Asella Referral and Teaching Hospital, Arsi Zone, Oromia Regional State, Ethiopia, in 2020. Methods. An institution-based cross-sectional survey was conducted on 115 hypertensive patients who visited the follow-up clinic at Asella Referral and Teaching Hospital from December 24, 2020, to January 15, 2021. Data were entered into EpiData version 4.2.0.0 and exported to SPSS version 21.0 for statistical analysis. Binary and multivariable logistic regression analysis was used to assess the presence of statistical association between dependent and independent variables. Results. A total of 115 hypertensive patients were enrolled into the study, giving a response rate of 98.29%. The mean age of the study participants was 55.17 years (SD = 17.986). More than half of them (59 (51.3%)) were females. More than half of them (58 (50.4%)) were married. Nearly two-thirds of them (79 (68.7%)) had formal education. The level of nonadherence to self-care practices was 67.0% (n = 77, 95% CI: 60.0, 75.7). Meanwhile, the patient’s level of nonadherence to antihypertensive medications was 16.5% (n = 19, 95% CI: 10.4, 24.3). The multivariable logistic regression analysis showed that age >45 years (AOR = 2.89, 95% CI: 1.16, 7.18), having no formal education (AOR = 1.67, 95% CI: 1.32, 3.74), and having ≤5 years’ duration since diagnoses of hypertension (AOR = 1.56, 95% CI: 1.07, 3.25) were factors significantly associated with nonadherence to self-care practices. Being male (AOR = 2.09, 95% CI: 1.93, 9.59), being married (AOR = 4.22, 95% CI: 1.29, 13.76), and having an average monthly income of ≤2500 ETB (AOR = 1.58, 95% CI: 1.09, 7.08) were factors significantly associated with nonadherence to medications. Conclusion. In the present study, the level of both nonadherence to self-care practices and antihypertensive medications was relatively high. There is a need to initiate programs that could create awareness about adherence to self-care practices and antihypertensive medications among hypertensive patients to improve their level of adherence.


2018 ◽  
Vol 11 (1) ◽  
pp. 62-71 ◽  
Author(s):  
Habtamu Dame Berisa ◽  
Mohammed Gebre Dedefo

Background:Hypertension is an overwhelming global challenge. Increasing awareness and diagnosis of hypertension, and improving control of blood pressure with appropriate treatment are considered critical public health initiatives to reduce cardiovascular morbidity and mortality.Objective:To assess non-adherence-related factors to antihypertensive medications among hypertensive patients on follow up at Nedjo General Hospital.Methods:A cross-sectional study was conducted among hypertensive patients on follow up at Nedjo General Hospital from March 15 to May 5, 2015. A total of 172 hypertensive patients who were available during study period were included in the study. To identify the independent non-adherence-related factors, backward logistic regression analysis was used.Results:Only 54 (31.4%) of the study participants were adherent to their treatment. On multivariable logistic analysis non-adherence was more likely to occur among those with age of>55 years (Adjusted odds ratio (AOR) = 0.10, 95% CI = 0.01-0.85, p=0.035), illiteracy (AOR = 6.76, 95% CI = 1.01-45.08, p=0.049), income status of <500 Ethiopian birr (AOR = 18.51, 95% CI = 1.95-176.06, p=0.011), duration of treatments of>5 years (AOR = 5.41, 95% CI = 1.08-27.22, p=0.041), physical inactivity (AOR = 34.51, 95% CI = 4.66-255.89, p=0.001) and knowledge deficit about hypertension and its treatment (AOR = 7.67, 95% CI = 2.48-23.73, p<0.001).Conclusion:A finding of this study revealed that an adherence status of study participants was low. Thus, greater effort is needed to improve patient adherence to antihypertensive medications.


2021 ◽  
Vol 5 (1) ◽  
pp. 031-037
Author(s):  
Addis Sisay Gedamu ◽  
Kassahun Sewunet Ademe ◽  
Ayele Samuel Anteneh ◽  
Nega Abebe Dires ◽  
Tegegne Kirubel Dagnaw

Background: Diabetes mellitus is a common health problem in the world and Africa including Ethiopia. Its complication is the major cause of morbidity and mortality of people due to improper self-care practice. Objective: To assess self-care practices and associated factors among type 2 adult diabetic patients on follow-up clinic of Dessie referral hospital, Ethiopia. Method: Institutional based cross sectional study was conducted. Total of 278 type 2 diabetic patients was selected by systematic random sampling technique and data was collected by interviewer administered pretested questionnaire. Epidata 3.1 and SPSS version 23 software were used for data entry and analysis, respectively. In bivariate analysis, variables having a p - value of < 0.2 were entered to multivariate analysis model and statistical significance was declared at p - value of < 0.05 and 95% confidence interval. Results: The response rate was 269 (96.76%) of the total 278 participants. Among the respondents 150(55.8%) had good diabetic self-care practice. This study showed that primary school education level (AOR=2.592, 95%CI=1.104-6.087, p = 0.029), secondary school education level (AOR=3.873, 95%CI=1.325-11.323, p = 0.013), college/university graduate (AOR=3.030, 95%CI=1.276-7.197, 0.012), attended diabetic education regularly (AOR=2.981, 95%CI=1.050-8.462, p = 0.040), member of diabetic association (AOR=3.496, 95%CI=1.440-8.483, p = 0.006) and having glucometer at home (AOR=2.634, 95%CI=1.357-5.111, p = 0.004) were significantly associated with diabetes self-care practice. Conclusion: Nearly half of diabetic patients had poor self care practice. Hence, there is a need to improve diabetic self-care practice. Attention should be given by policy makers, Dessie referral hospital, health care professionals, diabetic associations and researchers.


2018 ◽  
Vol 35 (2) ◽  
pp. 51-55
Author(s):  
Sitaram Khadka ◽  
Rinku Joshi ◽  
Dhan Bahadur Shrestha ◽  
Drishti Shah ◽  
Niroj Bhandari ◽  
...  

Background: Vasodilatory edema is a frequently encountered side effect among hypertensive patients using antihypertensive drugs. This dose-dependent adverse effect is seen more commonly with amlodipine, so low-dose combination therapy is often used and preferred in practice. Pedal edema following use of amlodipine is scarcely studied in Nepalese population so far. Objectives: To find out the prevalence of amlodipine-associated pedal edema and its relation with other variables among patients presenting to a tertiary care center of Kathmandu, Nepal. Methods: A prospective cross-sectional study was conducted among hypertensive patients using amlodipine in combination with or without other antihypertensive medications under regular follow-up in an outpatient department of internal medicine of Shree Birendra Hospital, Kathmandu, Nepal, during the 7-month period from September 2017 to March 2018. The prevalence of pedal edema and its relation with amlodipine dose, duration, and other factors were studied using χ2 test and logistic regression using SPSS version 22. Results: A total of 505 patients were observed during the study period, with the mean age of the population being 61.5 ± 13.4 years. Among the cases studied, edema was present in 79 (15.6%) cases. Use of amlodipine longer than 5 years was 21.65 (confidence interval [CI] = 9.575-48.970, P ˂ .001) times more likely to exhibit pedal edema; similarly, there was 2.149 (CI = 1.209-3.820, P = .009) times higher risk of having pedal edema in hypertensive individuals with other comorbidities. Increasing the dose of amlodipine has increased the likelihood of having pedal edema, but it is not statistically significant (odds ratio = 2.804, CI = 0.423-18.584, P = .285). Conclusion and Relevance: Significant number of hypertensive patients using amlodipine developed pedal edema. Likelihood of vasodilatory edema increases with the presence of comorbidities, higher dose, along with longer duration of amlodipine use.


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