The Protective Role of Racial Identity and Africentric Worldview in the Association Between Racial Discrimination and Blood Pressure

2012 ◽  
Vol 74 (5) ◽  
pp. 509-516 ◽  
Author(s):  
Enrique W. Neblett ◽  
Sierra E. Carter
Keyword(s):  
Blood Pressure ◽  
Racial Identity ◽  
Racial Discrimination ◽  
Protective Role

scholarly journals Evaluating the Protective Role of Racial Identity in Children with Sickle Cell Disease

2012 ◽  
Vol 37 (8) ◽  
pp. 832-842 ◽  
Author(s):  
C. S. Lim ◽  
J. S. Welkom ◽  
L. L. Cohen ◽  
I. Osunkwo
Keyword(s):  
Racial Identity ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Protective Role ◽  
Cell Disease

scholarly journals Explore the Protective Role of Obesity in the Progression of Myocardial Infarction

2021 ◽  
Vol 8 ◽  
Author(s):  
Siyuan Zhao ◽  
Rongyuan Cao ◽  
Shuhua Zhang ◽  
Yan Kang
Keyword(s):  
Myocardial Infarction ◽  
Blood Pressure ◽  
Regulatory Networks ◽  
Large Scale ◽  
Enrichment Analysis ◽  
Protective Role ◽  
Gene Set Enrichment Analysis ◽  
Shortest Path Analysis ◽  
Acute Mi

Obesity has been shown as a risk factor to increase the incidence of myocardial infarction (MI). However, obesity has also been linked to the decreased mortality of acute MI with unknown mechanisms. Here, we firstly used large-scale literature data mining to identify obesity downstream targets and MI upstream regulators with polarity, based on which an obesity-MI regulatory network was constructed. Then, a gene set enrichment analysis was conducted to explore the functional profile of the genes involved in the obesity-MI regulatory networks. After that, a mega-analysis using MI RNA expression datasets was conducted to test the expression of obesity-specific genes in MI patients, followed by a shortest-path analysis to explore any potential gene-MI association. Our results suggested that obesity could inhibit 11 MI promoters, including NPPB, NPPA, IRS1, SMAD3, MIR155, ADRB1, AVP, MAPK14, MC3R, ROCK1, and COL3A1, which were mainly involved in blood pressure-related pathways. Our study suggested that obesity could influence MI progression by driving multiple genes associated with blood pressure regulation. Moreover, PTH could be a novel obesity driven gene associated with the pathogenesis of MI, which needs further validation.

scholarly journals Nigella sativaand Its Protective Role in Oxidative Stress and Hypertension

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Xin-Fang Leong ◽  
Mohd Rais Mustafa ◽  
Kamsiah Jaarin
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Potential Role ◽  
Nigella Sativa ◽  
Peripheral Resistance ◽  
Reduce Blood Pressure ◽  
Protective Role ◽  
Subsequent Increase ◽  
Artery Disease

Hypertension increases the risk for a variety of cardiovascular diseases, including stroke, coronary artery disease, heart failure, and peripheral vascular disease. The increase in oxidative stress has been associated with the pathogenesis of hypertension. Increase of blood pressure is due to an imbalance between antioxidants defence mechanisms and free radical productions. Excessive production of reactive oxygen species reduces nitric oxide bioavailability leading to an endothelial dysfunction and a subsequent increase in total peripheral resistance. Hypertension can cause few symptoms until it reaches the advanced stage and poses serious health problems with lifelong consequences. Hypertensive patients are required to take drugs for life to control the hypertension and prevent complications. Some of these drugs are expensive and may have adverse reactions. Hence, it is timely to examine scientifically, complimentary therapies that are more effective and with minimal undesirable effects.Nigella sativa(NS) and its active constituents have been documented to exhibit antioxidant, hypotensive, calcium channel blockade and diuretic properties which may contribute to reduce blood pressure. This suggests a potential role of NS in the management of hypertension, and thus more studies should be conducted to evaluate its effectiveness.

Inter-relations between ethnic-racial discrimination and ethnic-racial identity among early adolescents

2020 ◽  
Author(s):  
Juan Del Toro ◽  
Diane Hughes ◽  
niobe way
Keyword(s):  
Racial Identity ◽  
Racial Discrimination ◽  
Early Adolescence ◽  
Early Adolescents ◽  
Identity Exploration ◽  
Identity Processes ◽  
Path Analyses ◽  
One Year ◽  
Public Regard

We examined whether the longitudinal inter-relation between discrimination and identity varies according to the perpetrator of discrimination. We used three waves of data from early adolescents (n = 387; ages 11-12 at Wave 1) to assess the strength and direction of relations between perceived discrimination from adults and peers vis-à-vis ethnic-racial identity exploration, commitment, private regard, and public regard. Cross-lagged autoregressive path analyses showed that more frequent discrimination, regardless of source, had reciprocal and significant longitudinal inter-relations with exploration and public regard. Peer discrimination predicted lower commitment and private regard one year later, whereas adult discrimination did not. We discuss the implications of these findings as they relate to the role of peers and ethnic-racial identity processes during early adolescence.

scholarly journals Pathways from racial discrimination to cortisol/DHEA imbalance: protective role of religious involvement

2018 ◽  
pp. 1-18 ◽  
Author(s):  
Daniel B. Lee ◽  
Melissa K. Peckins ◽  
Alison L. Miller ◽  
Meredith O. Hope ◽  
Enrique W. Neblett ◽  
...  
Keyword(s):  
Racial Discrimination ◽  
Religious Involvement ◽  
Protective Role

scholarly journals The Role of Racial Identity and Implicit Racial Bias in Self-Reported Racial Discrimination: Implications for Depression Among African American Men

2017 ◽  
Vol 43 (8) ◽  
pp. 789-812 ◽  
Author(s):  
David H. Chae ◽  
Wizdom A. Powell ◽  
Amani M. Nuru-Jeter ◽  
Mia A. Smith-Bynum ◽  
Eleanor K. Seaton ◽  
...  
Keyword(s):  
African American ◽  
Racial Identity ◽  
Racial Discrimination ◽  
Racial Bias ◽  
African American Men ◽  
Implicit Racial Bias

scholarly journals The role of Dietary Approaches to Stop Hypertension (DASH) diet food groups in blood pressure in type 2 diabetes

2011 ◽  
Vol 108 (1) ◽  
pp. 155-162 ◽  
Author(s):  
Tatiana Pedroso de Paula ◽  
Thais Steemburgo ◽  
Jussara Carnevale de Almeida ◽  
Valesca Dall'Alba ◽  
Jorge Luiz Gross ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Daily Intake ◽  
Cross Sectional Study ◽  
Protective Role ◽  
Food Groups ◽  
Cross Sectional ◽  
Dash Diet

The role of each Dietary Approaches to Stop Hypertension (DASH) diet component in blood pressure (BP) of patients with diabetes is still uncertain. The aim of the present study was to evaluate possible associations of the recommended food groups of the DASH diet eating plan with BP values in patients with type 2 diabetes. In the present cross-sectional study, 225 patients with type 2 diabetes (age 61·1 (sd10·4) years; diabetes duration 13·1 (sd9·1) years; males 48·4 %; BMI 28·5 (sd4·3) kg/m2; HbA1c 7·1 (sd1·3) %; systolic BP 136·7 (sd20·0) mmHg; diastolic BP 78·4 (sd11·8) mmHg) without dietary counselling during the previous 6 months had their dietary intake assessed by 3 d weighed-diet records. Patients were divided into two groups according to BP tertiles: LOW BP (first tertile) and HIGH BP (second plus third tertiles). Multivariate logistic regression models demonstrated that the daily intake of 80 g of fruits per 4184 kJ (1000 kcal) (OR 0·781; 95 % CI 0·617, 0·987;P = 0·039) or 50 g of vegetables per 4184 kJ (1000 kcal) (OR 0·781; 95 % CI 0·618, 0·988;P = 0·040) reduced the chance of the presence of HIGH mean BP (MBP ≥ 92 mmHg) by 22 % each, adjusted for possible confounders. In conclusion, fruit and vegetables were the food groups of the DASH diet associated with reduced BP values in patients with type 2 diabetes, and their consumption might play a protective role against increased BP values.

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