Affect and accessibility

Depressed patients experience thoughts with predominantly negative content. This could be because depressed mood increases the accessibility, or availability, of negative memories relative to that of positive memories. Investigations of the effects of experimentally induced and naturally occurring variations in mood on the recall of memories of personal experiences found results consistent with this suggestion; in depressed mood the latency of retrieval of positive memories was increased, the probability of retrieval of positive memories was decreased, and the probability of retrieval of negative memories was increased. The recall of certain positive and negative words was also found to be differentially affected by mood at recall. It is hypothesized that the effects of current mood on accessibility depend on the extent to which the events to which memories relate have previously been associated with different moods. Differences in the effects of mood on accessibility consistent with this suggestion have been obtained.

1996 ◽  
Vol 26 (6) ◽  
pp. 1271-1276 ◽  
Author(s):  
C. R. Brewin ◽  
E. Hunter ◽  
F. Carroll ◽  
P. Tata

SynopsisA sample of 31 male and female depressed patients was interviewed to investigate spontaneous, intrusive memories of immediate and past life events. Previous findings that depressed patients experience high frequency intrusive memories were confirmed, as was an association between intrusive memories of childhood abuse and severity of depression. Patients reported intrusive memories for a variety of other events, particularly involving illness and death. Limited support was obtained for the hypotheses that the course of depression would be related to the activation of negative memories, and that immediate life events would trigger the activation of memories of similar events from the past.


2020 ◽  
pp. 135910452097869
Author(s):  
Anne Steenbakkers ◽  
Steffie van der Steen ◽  
Hans Grietens

This study explored what contributes to successful family foster care from the perspective of young people by asking them about their most positive memory of family foster care. Forty-four Dutch adolescents and young adults (aged 16–28) participated in this study and shared their most positive memory in a short interview. Their answers were qualitatively analyzed using reflexive thematic analysis, supplemented with an analysis of the structure of their memories. The thematic analysis resulted in the themes Belongingness, Receiving support, Normal family life, It is better than before, and Seeing yourself grow. The structural analysis showed that young people both shared memories related to specific events, as well as memories that portrayed how they felt for a prolonged period of time. In addition, young people were inclined to share negative memories alongside the positive memories. These results highlight that, in order to build a sense of belonging, it is important that of foster parents create a normal family environment for foster children and provide continuous support. Moreover, the negative memories shared by participants are discussed in light of a bias resulting from earlier traumatic experiences.


1953 ◽  
Vol 4 (4) ◽  
pp. 430 ◽  
Author(s):  
RH Hayman

Occasions of unduly heavy and prolonged rainfall during the period April 1946 – July 1951 resulted in the occurrence of fleece-rot in sheep of the Field Station flock in each of the six years. Data obtained from periodic examinations of the flock have been related to the nature of climatic conditions associated with outbreaks of the disease. They show that when rain occurs in falls of sufficient intensity and frequency to wet sheep to the skin for a period of a week or more, fleece-rot may be expected to develop in some of them. The longer the period for which the sheep are kept wet, the greater the number in a flock which will be affected. Fleece-rot was experimentally induced in four out of five Merino sheep known to be susceptible to the condition, whereas five animals known to be resistant were unaffected by the same treatment. Microscopic examination of skin sections taken from naturally occurring cases revealed the presence of a dermatitis. A similar condition was observed in skin sections from the animals in which fleece-rot was experimentally induced. Young sheep were found to be more susceptible than old. There was no association between degree of wrinkling and susceptibility or between 'grip' and susceptibility. When subjectively-appraised attributes of the fleece were related to the occurrence of fleece-rot, confusing results were obtained. However, when measured fleece data, obtained from a group of Merino sheep which had been under observation for four consecutive years, were considered, it was found that those for clean-scoured yield, wax and suint ratio, and density of fibre population per unit area of skin surface, were related to resistance or susceptibility. Nevertheless, a number of animals were found which were susceptible or resistant to the disease despite the nature of their fleece attributes. Differences in susceptibility were found between families of Merino sheep. These are associated with between-family differences for the fleece attributes found to be important in fleece-rot reaction.


2020 ◽  
Vol 10 ◽  
pp. 204512532093792 ◽  
Author(s):  
Lucas Primo de Carvalho Alves ◽  
Neusa Sica da Rocha

Background Six melancholic features (MFs) of the Hamilton Depression Rating Scale (HAM-D6) represent the construct of melancholia along a continuum of severity (from least to most severe: depressed mood, work and activities, somatic symptoms, psychic anxiety, guilty feelings, psychomotor retardation). We aimed to evaluate the association between these MFs and inflammatory cytokines (IC) in the blood. Methods Each IC [interferon gamma (IFN-γ), tumor necrosis factor alpha (TNF-α), interleukin 2 (IL-2), IL-4, IL-6, IL-10, and IL-17] was associated with the HAM-D6 MFs of 139 severely depressed inpatients, using multiple linear regressions adjusted for covariates. Levels were compared with those of 100 healthy controls. Results Depressed mood was associated with higher levels of IL-4 ( β = 0.167; p = 0.041). Psychic anxiety: lower IL-17 levels ( β = –0.173; p = 0.039). Guilt feelings: lower IL-2 levels ( β = −0.168; p = 0.041) Psychomotor retardation: higher IL-6 levels ( β = 0.195; p = 0.017). Depressed patients’ TNF-α, INF-γ, and IL-4 levels were not significantly different from controls. Depressed patients’ IL-2, IL-6, IL-10, and IL-17 levels were higher than those of controls ( p <0.001). Conclusion Less severe MFs (depressed mood, psychic anxiety, and guilt feelings) were associated with an anti-inflammatory pattern (higher IL-4, lower IL-17 and lower IL-2, respectively). The presence of the most severe MF, psychomotor retardation, was associated with a higher pro-inflammatory response (higher IL-6).


2008 ◽  
Vol 46 (3) ◽  
pp. 322-333 ◽  
Author(s):  
Loretxu Bergouignan ◽  
Cédric Lemogne ◽  
Aurélie Foucher ◽  
Estelle Longin ◽  
Damien Vistoli ◽  
...  

1993 ◽  
Vol 36 (1) ◽  
pp. 39-55 ◽  
Author(s):  
Janet Anderson Yang ◽  
Lynn P. Rehm

An autobiographical memory task was used to study memory processes and depression in elderly individuals. Twenty-seven nondepressed and twenty-seven depressed elderly participants recalled thirty memories. Each memory was self-rated for happiness versus sadness and the degree of importance of the event at the time the event occurred (i.e., “then”) and looking back on the event (“now”). Nondepressed participants perceived greater positive change in affective tone between “then” and “now” ratings. Depressed participants recalled more memories rated as sad “now” than nondepressed, and perceived negative and positive memories to become more neutral than nondepressed participants. These results are consistent with a mood congruence hypothesis, in that participants recalled more memories affectively consistent with current mood, and a self-enhancement view of reminiscing, such that recalling memories evaluated as happier was associated with less depression.


1963 ◽  
Vol 23 (6) ◽  
pp. 579-587 ◽  
Author(s):  
RALPH F. KNOPF ◽  
STEFAN S. FAJANS ◽  
JOHN C. FLOYD ◽  
JEROME W. CONN

1969 ◽  
Vol 42 (1) ◽  
pp. 170-184 ◽  
Author(s):  
Lewis G. Tilney ◽  
Douglas Marsland

A fine structural study has been carried out on the various formed elements present before, during, and after the first cleavage division, not only in normally developing Arbacia eggs, but also in eggs which have been induced to cleave prematurely by high-pressure centrifugation. The aim has been to ascertain whether or not any of the morphologically identifiable components may be involved in initiating the furrowing process. Also, attention has been given to the fine structure of the cytoplasmic cortex, particulary in the walls of the furrow, in the hope of reaching a better understanding of the mechanics of cleavage. The annulate lamellae and the membranous envelope of the nucleus are the only formed elements which disappear shortly before cleavage, not only in eggs undergoing normal division, but also in eggs which have been induced to cleave ahead of schedule by high-pressure, high-force centrifugation. Therefore, it is suggested as a tentative hypothesis that materials liberated upon disintegration of the nuclear membrane and the annulate lamellae play an essential role in initiating and effecting the furrowing reaction, especially since the stratification of these elements in experimentally induced eggs corresponds to the position of the developing furrow. Another of the membranous elements in the egg, the Golgi complex, shows considerable modification as a result of high-pressure centrifugation, but these structures do not undergo disintegration. Rather, they become curled into rounded bodies. The vacuole population is not greatly affected by inducing treatments. During cleavage, both naturally occurring and experimentally induced, a considerable number of 50 A filaments appear in the denser cytoplasmic cortex, but only in the walls of the furrow. These filaments are similar to those which have been demonstrated in a number of contractile cells. Accordingly, it is suggested that this fibrillar system may be actively involved in the development of the cleavage force.


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