scholarly journals Continuing the debate on the role of Quaternary environmental change for macroevolution

2004 ◽  
Vol 359 (1442) ◽  
pp. 295-303 ◽  
Author(s):  
K. D. Bennett
Keyword(s):  
Environmental Change ◽  
Time Scales ◽  
Causal Factors ◽  
Species Response ◽  
The Past ◽  
Dna Characterization ◽  
Evolutionary Consequences ◽  
Response To Environmental Change

The Quaternary has been a period of dramatic environmental change for the past 1.8 Myr, with major shifts in distributions and abundances of terrestrial and marine organisms. The evolutionary consequences of this have been debated since the nineteenth century. However, the lack of accurate relative and absolute time–scales for evolutions and environmental change inhibited progress. We do now have an understanding of time–scales. Palaeoecology has demonstrated the individualistic nature of species' response to environmental change, but lacks a means of determining ancestry. DNA characterization of modern populations in relation to their distributions nicely complements palaeoecological results by contributing ancestry. The chance to understand how species originate and the causal factors of speciation (environmental change or otherwise) may be within reach.

USING HISTORICAL ANNUAL REPORTS IN TEACHING: LETTING THE PAST BENEFIT THE PRESENT

1992 ◽  
Vol 19 (1) ◽  
pp. 29-50 ◽  
Author(s):  
Joel Amernic ◽  
Ramy Elitzur
Keyword(s):  
Environmental Change ◽  
Cash Flow ◽  
Accounting Education ◽  
Annual Reports ◽  
The Past ◽  
Response To Environmental Change

In this article, it is suggested that accounting education may be enhanced by the use of published historical accounting materials, such as annual reports. Comparing such materials with modern reports serves to reinforce the notion that accounting evolves in response to environmental change. Further, requiring students to analytically derive cash flow statements from historical published annual reports provides several direct pedagogical benefits.

Electron Microscope Characterization of Pulse Annealed Semiconductors

1980 ◽  
Vol 2 ◽  
Author(s):  
A. G. CULLIS
Keyword(s):  
Electron Microscopy ◽  
Defect Structure ◽  
Device Fabrication ◽  
Fabrication Technology ◽  
The Past ◽  
Semiconductor Structures ◽  
Pulse Processing ◽  
Processing Techniques

ABSTRACTThe pulse processing techniques that have assumed prominence over the past few years offer various important advantages for device fabrication technology. However, the usefulness of each individual method depends substantially upon the specific annealing mechanism involved. This article demonstrates the role of electron microscopy in elucidating such mechanisms and in analysing annealed semiconductor structures of importance to both research workers and semiconductor technologists. The range of laser and electron beam pulse annealing methods is covered and defect structure transitions observed are related to the solid and liquid phase processes occurring. Characteristic impurity trapping and segregation phenomena are described.

Species Response to Environmental Change: Impacts of Food Web Interactions and Evolution

Science ◽  
2009 ◽  
Vol 323 (5919) ◽  
pp. 1347-1350 ◽  
Author(s):  
J. P. Harmon ◽  
N. A. Moran ◽  
A. R. Ives
Keyword(s):  
Environmental Change ◽  
Food Web ◽  
Food Web Interactions ◽  
Species Response ◽  
Response To Environmental Change

scholarly journals Global Phylogeographic and Admixture Patterns in Grey Wolves and Genetic Legacy of An Ancient Siberian Lineage

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Małgorzata Pilot ◽  
Andre E. Moura ◽  
Innokentiy M. Okhlopkov ◽  
Nikolay V. Mamaev ◽  
Abdulaziz N. Alagaili ◽  
...  
Keyword(s):  
Environmental Change ◽  
Environmental Changes ◽  
Phylogeographic Structure ◽  
Evolutionary Relationships ◽  
Clustering Methods ◽  
Species Response ◽  
Genome Wide ◽  
Response To Environmental Change ◽  
Ambiguous Position ◽  
Insight Into

AbstractThe evolutionary relationships between extinct and extant lineages provide important insight into species’ response to environmental change. The grey wolf is among the few Holarctic large carnivores that survived the Late Pleistocene megafaunal extinctions, responding to that period’s profound environmental changes with loss of distinct lineages and phylogeographic shifts, and undergoing domestication. We reconstructed global genome-wide phylogeographic patterns in modern wolves, including previously underrepresented Siberian wolves, and assessed their evolutionary relationships with a previously genotyped wolf from Taimyr, Siberia, dated at 35 Kya. The inferred phylogeographic structure was affected by admixture with dogs, coyotes and golden jackals, stressing the importance of accounting for this process in phylogeographic studies. The Taimyr lineage was distinct from modern Siberian wolves and constituted a sister lineage of modern Eurasian wolves and domestic dogs, with an ambiguous position relative to North American wolves. We detected gene flow from the Taimyr lineage to Arctic dog breeds, but population clustering methods indicated closer similarity of the Taimyr wolf to modern wolves than dogs, implying complex post-divergence relationships among these lineages. Our study shows that introgression from ecologically diverse con-specific and con-generic populations was common in wolves’ evolutionary history, and could have facilitated their adaptation to environmental change.

scholarly journals Roles, Responsibilities, and Needs of Institutional GME Leaders: A Multinational Characterization of Designated Institutional Officials

2019 ◽  
Vol 11 (4s) ◽  
pp. 110-117 ◽  
Author(s):  
Sawsan Abdel-Razig ◽  
Halah Ibrahim
Keyword(s):  
Professional Development ◽  
Medical Education ◽  
Middle East ◽  
Best Practices ◽  
Job Descriptions ◽  
The Past ◽  
Professional Development Needs ◽  
Accredited Institutions

ABSTRACT Background Since 2012, several academic centers in the Middle East have attained accreditation by the Accreditation Council for Graduate Medical Education International (ACGME-I). An emerging group of GME leaders have assumed the role of designated institutional official (DIO), leading their institutions to accreditation. Despite these DIOs' key positions in driving GME reform, there is a lack of published studies on the roles, responsibilities, and needs of DIOs in international settings. Objective We examined the characteristics, roles, responsibilities, and needs of DIOs in the Middle East. Methods A questionnaire was electronically distributed from December 2018 to February 2019 to all current and former DIOs in ACGME-I accredited institutions in the Middle East. Results Of 16 surveys sent, 11 (69%) were returned. All DIOs were physicians; the majority were women less than 55 years of age, and assumed the role of DIO in the past decade. Most DIOs felt prepared for the position and well supported by their institution and their program directors. All reported having additional roles beyond the DIO position. Most identified the most challenging aspect of their role related to GME budgets, training for their responsibilities, sharing best practices and documents such as DIO job descriptions and other key documents, and DIO training. Conclusions ACGME-I accreditation is a critical driver of efforts to define the DIO role. DIOs in the Middle East share common perceptions, experiences, and needs. Further research should identify professional development needs in an increasingly diverse international worldwide DIO community.

Evolutionary paleoecology: recent contributions to evolutionary theory

Paleobiology ◽  
1985 ◽  
Vol 11 (1) ◽  
pp. 91-104 ◽  
Author(s):  
Jennifer A. Kitchell
Keyword(s):  
Evolutionary Theory ◽  
Fossil Record ◽  
Differential Rate ◽  
Faunal Turnover ◽  
The Past ◽  
The Individual ◽  
Evolutionary Consequences ◽  
Theoretical Issues ◽  
Species Ecology

In the past decade, evolutionary paleoecology has shifted away from corroborative research of the “me-too-ecology” type toward its proper domain—the evolutionary consequences of ecological properties, roles, and strategies at the individual, population, community, and species levels. The science of evolutionary paleoecology tests for linkage between a species' ecology and its macroevolutionary history. Do the ecological characters of species within clades influence differential rate dynamics, particularly rates of faunal turnover and diversification? Intellectual coequality, once hampered by the misunderstanding that the role of paleoecology is to find examples of past ecology imperfectly entombed in the fossil record, is strengthened by the increasing number of evolutionary ecologists who have called for explicit paleontological contributions to resolve theoretical issues. The fossil record provides a necessary perspective to an understanding of process.

Exploring exploration: the role of affective states as forces that hinder change

2019 ◽  
Vol 29 (1) ◽  
pp. 207-223
Author(s):  
Stefano Brusoni ◽  
Daniella Laureiro-Martínez ◽  
Nicola Canessa ◽  
Maurizio Zollo
Keyword(s):  
Environmental Change ◽  
The Other ◽  
Affective States ◽  
Cognitive Sciences ◽  
The Past ◽  
Other Hand ◽  
Long Time ◽  
Tentative Evidence ◽  
Negative Affective States

Abstract In this article we argue that in order to understand failure or success in adapting to environmental change, we should better understand why people hesitate to pursue novel choices. This article asks: what forces hinder individuals’ exploration choices of different alternatives, and hence their ability to learn from them? To answer this question, this article looks to the cognitive sciences to identify a set of plausible mechanisms that hinder people’s tendency to explore. So far, “exploration” has been studied as a relatively monolithic behavior. Instead, we propose that exploration can be characterized in terms of some distinctive forces behind it. On one hand, agents experience “attachment” to choices that proved successful in the past, and hence comfort when sticking with them. On the other hand, they also experience concerns about less familiar options, as they lack knowledge about “distant” choices that have not been tried for a long time, or ever. We propose that high attachment is related to anxiety, and high distance to fear. Both these negative affective states hinder exploration. We find and discuss preliminary and tentative evidence of this effect.

scholarly journals Epigenetic Regulation of the Wnt/β-Catenin Signaling Pathway in Cancer

2021 ◽  
Vol 12 ◽  
Author(s):  
Ankita Sharma ◽  
Rafeeq Mir ◽  
Sanjeev Galande
Keyword(s):  
Regulatory Networks ◽  
Target Genes ◽  
Therapeutic Interventions ◽  
The Past ◽  
Epigenetic Machinery ◽  
Cancer Initiation ◽  
And Migration ◽  
Regenerative Therapies

Studies over the past four decades have elucidated the role of Wnt/β-catenin mediated regulation in cell proliferation, differentiation and migration. These processes are fundamental to embryonic development, regeneration potential of tissues, as well as cancer initiation and progression. In this review, we focus on the epigenetic players which influence the Wnt/β-catenin pathway via modulation of its components and coordinated regulation of the Wnt target genes. The role played by crosstalk with other signaling pathways mediating tumorigenesis is also elaborated. The Hippo/YAP pathway is particularly emphasized due to its extensive crosstalk via the Wnt destruction complex. Further, we highlight the recent advances in developing potential therapeutic interventions targeting the epigenetic machinery based on the characterization of these regulatory networks for effective treatment of various cancers and also for regenerative therapies.

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