scholarly journals Gut microbiome of poison arrow frogs and their potential role in toxin sequestration

2019 ◽  
Vol 1 (1A) ◽  
Author(s):  
Karen Siu-Ting ◽  
Jess Friedersdorff ◽  
David Carreño ◽  
Ben Thomas ◽  
Jamie Newbold ◽  
...  
Keyword(s):  
Gut Microbiome ◽  
Potential Role ◽  
Toxin Sequestration

scholarly journals Effect on Intermediary Metabolism and Digestive Parameters of the High Substitution of Fishmeal with Insect Meal in Sparus aurata Feed

Insects ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 965
Author(s):  
Dmitri Fabrikov ◽  
María del Carmen Vargas-García ◽  
Fernando G. Barroso ◽  
María José Sánchez-Muros ◽  
Sylvia María Cacua Ortíz ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Gut Microbiome ◽  
Potential Role ◽  
Sparus Aurata ◽  
Growth Parameters ◽  
Fatty Acid Fraction ◽  
Fish Growth ◽  
Streptococcus Dysgalactiae ◽  
Growth Indices ◽  
Fish Performance

Hermetia illucens and Tenebrio molitor were tested on account of their potential to replace fish protein in feed. Two levels of replacement for H. illucens, 30% and 50% (H30 and H50), and one for T. molitor, 50% (T50), as well as an additional diet with a modified fatty acid fraction (H50M), were investigated in relation to juvenile Sparus aurata growth indices, enzyme activities and gut microbiome. A T50 diet showed similar results to a control (C) diet, with no significant differences regarding morphological indices and minor differences for nutritional indices. Regarding the gut microbiome, H50M was the diet which showed the more similar prokaryotic community to C, which suggests that fatty acid fractions might influence the composition of the gut microbiome. Nevertheless, differences appeared to be related to a redistribution of dominant species, while changes in species affiliation were limited to minoritary species. The positive correlation between some of these minoritary species (Peptostreptococcus russellii, Streptococcus dysgalactiae and Weisella confusa) and several fish growth parameters might explain differences between control and insect diets. Deciphering such uncertainty and revealing the potential role these unusual species may play on fish performance should be addressed in future investigations.

scholarly journals The Exposome and Immune Health in Times of the COVID-19 Pandemic

Nutrients ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 24
Author(s):  
Javier S. Morales ◽  
Pedro L. Valenzuela ◽  
Adrián Castillo-García ◽  
Javier Butragueño ◽  
David Jiménez-Pavón ◽  
...  
Keyword(s):  
Physical Activity ◽  
Body Weight ◽  
Circadian Rhythms ◽  
Immune Function ◽  
Weight Management ◽  
Gut Microbiome ◽  
Potential Role ◽  
Sun Exposure ◽  
Immune Health

Growing evidence supports the importance of lifestyle and environmental exposures—collectively referred to as the ‘exposome’—for ensuring immune health. In this narrative review, we summarize and discuss the effects of the different exposome components (physical activity, body weight management, diet, sun exposure, stress, sleep and circadian rhythms, pollution, smoking, and gut microbiome) on immune function and inflammation, particularly in the context of the current coronavirus disease 2019 (COVID-19) pandemic. We highlight the potential role of ‘exposome improvements’ in the prevention—or amelioration, once established—of this disease as well as their effect on the response to vaccination. In light of the existing evidence, the promotion of a healthy exposome should be a cornerstone in the prevention and management of the COVID-19 pandemic and other eventual pandemics.

Potential Role of the Gut Microbiome in ALS: A Systematic Review

2018 ◽  
Vol 20 (5) ◽  
pp. 513-521 ◽  
Author(s):  
Michelle L. Wright ◽  
Christina Fournier ◽  
Madelyn C. Houser ◽  
Malú Tansey ◽  
Jonathan Glass ◽  
...  
Keyword(s):  
Mouse Model ◽  
Gut Microbiota ◽  
Gut Microbiome ◽  
Potential Role ◽  
Intestinal Epithelial ◽  
Emerging Therapies ◽  
Microbiome Profile ◽  
Subsequent Publication ◽  
Als Patients

Amyotrophic lateral sclerosis (ALS) etiology and pathophysiology are not well understood. Recent data suggest that dysbiosis of gut microbiota may contribute to ALS etiology and progression. This review aims to explore evidence of associations between gut microbiota and ALS etiology and pathophysiology. Databases were searched for publications relevant to the gut microbiome in ALS. Three publications provided primary evidence of changes in microbiome profiles in ALS. An ALS mouse model revealed damaged tight junction structure and increased permeability in the intestine versus controls along with a shifted microbiome profile, including decreased levels of butyrate-producing bacteria. In a subsequent publication, again using an ALS mouse model, researchers showed that dietary supplementation with butyrate relieved symptoms and lengthened both time to onset of weight loss and survival time. In a small study of ALS patients and healthy controls, investigators also found decreased levels of butyrate-producing bacteria. Essential for maintaining gut barrier integrity, butyrate is the preferred energy source of intestinal epithelial cells. Ten other articles were reviews and commentaries providing indirect support for a role of gut microbiota in ALS pathophysiology. Thus, these studies provide a modicum of evidence implicating gut microbiota in ALS disease, although more research is needed to confirm the connection and determine pathophysiologic mechanisms. Nurses caring for these patients need to understand the gut microbiome and its potential role in ALS in order to effectively counsel patients and their families about emerging therapies (e.g., prebiotics, probiotics, and fecal microbial transplant) and their off-label uses.

scholarly journals Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies

2020 ◽  
Vol 21 (15) ◽  
pp. 5275
Author(s):  
Margherita Di Costanzo ◽  
Laura Carucci ◽  
Roberto Berni Canani ◽  
Giacomo Biasucci
Keyword(s):  
Microbial Community ◽  
Gut Microbiome ◽  
Potential Role ◽  
Therapeutic Strategies ◽  
Pivotal Role ◽  
Food Allergies ◽  
Disease Course ◽  
Microbial Community Structures ◽  
Prevention And Treatment

The increasing prevalence and severity of pediatric food allergies (FA) demands innovative preventive and therapeutic strategies. Emerging evidence suggests a pivotal role for the gut microbiome in modulating susceptibility to FA. Studies have demonstrated that alteration of gut microbiome could precede FA, and that particular microbial community structures early in life could influence also the disease course. The identification of gut microbiome features in pediatric FA patients is driving new prevention and treatment approaches. This review is focused on the potential role of the gut microbiome as a target for FA prevention and treatment.

scholarly journals Gut microbiome and its potential role in obesity‐induced neuropathy

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
RAIZA BONOMO ◽  
Tyler Cook ◽  
Chaitanya Gavini ◽  
Virginie Mansuy‐Aubert
Keyword(s):  
Gut Microbiome ◽  
Potential Role
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