scholarly journals The diagnostic evaluation of Convolutional Neural Network (CNN) for the assessment of chest X-ray of patients infected with COVID-19

Author(s):  
Syed Usama Khalid Bukhari ◽  
Syed Safwan Khalid Bukhari ◽  
Asmara Syed ◽  
Syed Sajid Hussain Shah

AbstractIntroductionThe main target of COVID-19 is the lungs where it may cause pneumonia in severely ill patients. Chest X-ray is an important diagnostic test to assess the lung for the damaging effects of COVID-19. Many other microbial pathogens can also cause damage to lungs leading to pneumonia but there are certain radiological features which can favor the diagnosis of pneumonia caused by COVID-19. With the rising number of cases of COVID-19, it would be imperative to develop computer programs which may assist the health professionals in the prevailing scenario.Materials & MethodsA total of two hundred and seventy eight (278) images of chest X-rays have been assessed by applying ResNet-50 convolutional neural network architectures in the present study. The digital images were acquired from the public repositories provided by University of Montreal and National Institutes of Health. These digital images of Chest X-rays were divided into three groups labeled as normal, pneumonia and COVID-19. The third group contains digital images of chest X-rays of patients diagnosed with COVID-19 infection while the second group contains images of lung with pneumonia caused by other pathogens.ResultsThe radiological images included in the data set are 89 images of lungs with COVID-19 infection, 93 images of lungs without any radiological abnormality and 96 images of patient with pneumonia caused by other pathogens. In this data set, 80% of the images were employed for training, and 20% for testing. A pre-trained (on ImageNet data set) ResNet-50 architecture was used to diagnose the cases of COVID-19 infections on lung X-ray images. The analysis of the data revealed that computer vision based program achieved diagnostic accuracy of 98.18 %, and F1-score of 98.19.ConclusionThe performance of convolutional neural network regarding the differentiation of pulmonary changes caused by COVID-19 from the other type of pneumonias on digital images of the chest X-rays is excellent and it may be an extremely useful adjunct tool for the health professionals.

2021 ◽  
Vol 2071 (1) ◽  
pp. 012001
Author(s):  
J Ureta ◽  
A Shrestha

Abstract Tuberculosis(TB) is one of the top 10 causes of death worldwide, and drug-resistant TB is a major public health concern especially in resource-constrained countries. In such countries, molecular diagnosis of drug-resistant TB remains a challenge; and imaging tools such as X-rays, which are cheaply and widely available, can be a valuable supplemental resource for early detection and screening. This study uses a specialized convolutional neural network to perform binary classification of chest X-ray images to classify drug-resistant and drug-sensitive TB. The models were trained and validated using the TBPortals dataset which contains 2,973 labeled X-ray images from TB patients. The classifiers were able to identify the presence or absence of drug-resistant Tuberculosis with an AUROC between 0.66–0.67, which is an improvement over previous attempts using deep learning networks.


2021 ◽  
Vol 11 (21) ◽  
pp. 10301
Author(s):  
Muhammad Shoaib Farooq ◽  
Attique Ur Rehman ◽  
Muhammad Idrees ◽  
Muhammad Ahsan Raza ◽  
Jehad Ali ◽  
...  

COVID-19 has been difficult to diagnose and treat at an early stage all over the world. The numbers of patients showing symptoms for COVID-19 have caused medical facilities at hospitals to become unavailable or overcrowded, which is a major challenge. Studies have recently allowed us to determine that COVID-19 can be diagnosed with the aid of chest X-ray images. To combat the COVID-19 outbreak, developing a deep learning (DL) based model for automated COVID-19 diagnosis on chest X-ray is beneficial. In this research, we have proposed a customized convolutional neural network (CNN) model to detect COVID-19 from chest X-ray images. The model is based on nine layers which uses a binary classification method to differentiate between COVID-19 and normal chest X-rays. It provides COVID-19 detection early so the patients can be admitted in a timely fashion. The proposed model was trained and tested on two publicly available datasets. Cross-dataset studies are used to assess the robustness in a real-world context. Six hundred X-ray images were used for training and two hundred X-rays were used for validation of the model. The X-ray images of the dataset were preprocessed to improve the results and visualized for better analysis. The developed algorithm reached 98% precision, recall and f1-score. The cross-dataset studies also demonstrate the resilience of deep learning algorithms in a real-world context with 98.5 percent accuracy. Furthermore, a comparison table was created which shows that our proposed model outperforms other relative models in terms of accuracy. The quick and high-performance of our proposed DL-based customized model identifies COVID-19 patients quickly, which is helpful in controlling the COVID-19 outbreak.


2020 ◽  
Vol 10 (9) ◽  
pp. 3233 ◽  
Author(s):  
Tawsifur Rahman ◽  
Muhammad E. H. Chowdhury ◽  
Amith Khandakar ◽  
Khandaker R. Islam ◽  
Khandaker F. Islam ◽  
...  

Pneumonia is a life-threatening disease, which occurs in the lungs caused by either bacterial or viral infection. It can be life-endangering if not acted upon at the right time and thus the early diagnosis of pneumonia is vital. The paper aims to automatically detect bacterial and viral pneumonia using digital x-ray images. It provides a detailed report on advances in accurate detection of pneumonia and then presents the methodology adopted by the authors. Four different pre-trained deep Convolutional Neural Network (CNN): AlexNet, ResNet18, DenseNet201, and SqueezeNet were used for transfer learning. A total of 5247 chest X-ray images consisting of bacterial, viral, and normal chest x-rays images were preprocessed and trained for the transfer learning-based classification task. In this study, the authors have reported three schemes of classifications: normal vs. pneumonia, bacterial vs. viral pneumonia, and normal, bacterial, and viral pneumonia. The classification accuracy of normal and pneumonia images, bacterial and viral pneumonia images, and normal, bacterial, and viral pneumonia were 98%, 95%, and 93.3%, respectively. This is the highest accuracy, in any scheme, of the accuracies reported in the literature. Therefore, the proposed study can be useful in more quickly diagnosing pneumonia by the radiologist and can help in the fast airport screening of pneumonia patients.


Cancers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 4961
Author(s):  
Christoph Wallner ◽  
Mansoor Alam ◽  
Marius Drysch ◽  
Johannes Maximilian Wagner ◽  
Alexander Sogorski ◽  
...  

Introduction: soft tissue sarcomas are a subset of malignant tumors that are relatively rare and make up 1% of all malignant tumors in adulthood. Due to the rarity of these tumors, there are significant differences in quality in the diagnosis and treatment of these tumors. One paramount aspect is the diagnosis of hematogenous metastases in the lungs. Guidelines recommend routine lung imaging by means of X-rays. With the ever advancing AI-based diagnostic support, there has so far been no implementation for sarcomas. The aim of the study was to utilize AI to obtain analyzes regarding metastasis on lung X-rays in the most possible sensitive and specific manner in sarcoma patients. Methods: a Python script was created and trained using a set of lung X-rays with sarcoma metastases from a high-volume German-speaking sarcoma center. 26 patients with lung metastasis were included. For all patients chest X-ray with corresponding lung CT scans, and histological biopsies were available. The number of trainable images were expanded to 600. In order to evaluate the biological sensitivity and specificity, the script was tested on lung X-rays with a lung CT as control. Results: in this study we present a new type of convolutional neural network-based system with a precision of 71.2%, specificity of 90.5%, sensitivity of 94%, recall of 94% and accuracy of 91.2%. A good detection of even small findings was determined. Discussion: the created script establishes the option to check lung X-rays for metastases at a safe level, especially given this rare tumor entity.


Author(s):  
Zhi Qiao ◽  
Austin Bae ◽  
Lucas M Glass ◽  
Cao Xiao ◽  
Jimeng Sun

Abstract Objective The study sought to test the possibility of differentiating chest x-ray images of coronavirus disease 2019 (COVID-19) against other pneumonia and healthy patients using deep neural networks. Materials and Methods We construct the radiography (x-ray) imaging data from 2 publicly available sources, which include 5508 chest x-ray images across 2874 patients with 4 classes: normal, bacterial pneumonia, non–COVID-19 viral pneumonia, and COVID-19. To identify COVID-19, we propose a FLANNEL (Focal Loss bAsed Neural Network EnsembLe) model, a flexible module to ensemble several convolutional neural network models and fuse with a focal loss for accurate COVID-19 detection on class imbalance data. Results FLANNEL consistently outperforms baseline models on COVID-19 identification task in all metrics. Compared with the best baseline, FLANNEL shows a higher macro-F1 score, with 6% relative increase on the COVID-19 identification task, in which it achieves precision of 0.7833 ± 0.07, recall of 0.8609 ± 0.03, and F1 score of 0.8168 ± 0.03. Discussion Ensemble learning that combines multiple independent basis classifiers can increase the robustness and accuracy. We propose a neural weighing module to learn the importance weight for each base model and combine them via weighted ensemble to get the final classification results. In order to handle the class imbalance challenge, we adapt focal loss to our multiple classification task as the loss function. Conclusion FLANNEL effectively combines state-of-the-art convolutional neural network classification models and tackles class imbalance with focal loss to achieve better performance on COVID-19 detection from x-rays.


Author(s):  
R. Rohith ◽  
S.P.Syed Ibrahim

Tuberculosis is a life-threatening disease that mainly affects underdeveloped as well as developing nations. While lethal it is often resistive to antibiotics and the safest way to treat a patient is to detect the disease's presence as soon as possible. Various techniques have been developed to diagnose tuberculosis and radiography of the chest is one of such methods that works well for over a decade.. Though an effective method still the success depends on the medical officer who examines the chest X-rays. Thus ,this paper proposes an approach for detecting X-ray abnormalities using deep learning. The systems output is assessed on two open Montgomery and Shenz en chest X-ray datasets and accuracy of 84 percent is achieved.


2020 ◽  
Vol 52 (12) ◽  
pp. 590-601
Author(s):  
Emrah Irmak

In this paper, two novel, powerful, and robust convolutional neural network (CNN) architectures are designed and proposed for two different classification tasks using publicly available data sets. The first architecture is able to decide whether a given chest X-ray image of a patient contains COVID-19 or not with 98.92% average accuracy. The second CNN architecture is able to divide a given chest X-ray image of a patient into three classes (COVID-19 versus normal versus pneumonia) with 98.27% average accuracy. The hyperparameters of both CNN models are automatically determined using Grid Search. Experimental results on large clinical data sets show the effectiveness of the proposed architectures and demonstrate that the proposed algorithms can overcome the disadvantages mentioned above. Moreover, the proposed CNN models are fully automatic in terms of not requiring the extraction of diseased tissue, which is a great improvement of available automatic methods in the literature. To the best of the author’s knowledge, this study is the first study to detect COVID-19 disease from given chest X-ray images, using CNN, whose hyperparameters are automatically determined by the Grid Search. Another important contribution of this study is that it is the first CNN-based COVID-19 chest X-ray image classification study that uses the largest possible clinical data set. A total of 1,524 COVID-19, 1,527 pneumonia, and 1524 normal X-ray images are collected. It is aimed to collect the largest number of COVID-19 X-ray images that exist in the literature until the writing of this research paper.


Tuberculosis is one of the single infectious diseases which is one among the top ten causes of deaths. Eradication is only possible by timely diagnosis of disease and treatment at its early stage. But unfortunately, timely detection is lagging due to many reasons. In this angle we present a novel scheme for automatic detection of tuberculosis from chest X-ray images. The proposed method accurately detects the malady by performing graph cut segmentation followed by classification using convolutional neural network. The classifier facilitates the chest X-rays to be classified as normal or abnormal. Simulation results show that the accuracy of 94%, sensitivity of 96% and specificity of 84% obtained from the proposed system are comparable and even better than the existing reported methods.


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