scholarly journals Prevalence of influenza vaccination among adults with high-risk conditions, United States, 2019

2020 ◽  
Author(s):  
Saji Saraswathy Gopalan ◽  
Devi Kalyan Mishra ◽  
Ashis Kumar Das
Keyword(s):  
High Risk ◽  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Family Income ◽  
Influenza Infection ◽  
Insurance Coverage ◽  
Age Groups ◽  
National Sample ◽  
Medical Conditions ◽  
To Receive

AbstractBackgroundInfluenza could be associated with illnesses, severe complications, hospitalizations, and deaths among adults with high-risk medical conditions. Influenza vaccination reduces the risks and complications associated with influenza infection in high-risk conditions. We assessed the prevalence and predictors of influenza vaccination in a national sample of adults with high-risk medical conditions.MethodsUsing the nationally representative National Health Interview Survey of 2019, we estimated the prevalence of influenza vaccination among adults with high-risk conditions. We tested the associations between receipt of vaccination and sociodemographic predictors with adjusted multivariable logistic regression.ResultsOut of 15,258 adults with high-risk conditions, 56% reported receiving an influenza vaccine over the previous 12 months. Multivariable regressions show that respondents from older age groups, females, other race/ethnic group, married, higher annual family income, having a health insurance and those with more than two high-risk conditions are more likely to receive the influenza vaccine. However, adults from non-Hispanic Black race/ethnicity and living in the Southern census region are less likely to receive the vaccination. Education levels and living in a metro show no associations with vaccination status.ConclusionState authorities, primary physicians, specialists, and pharmacists have important roles in sensitizing and reminding individuals with high-risk conditions to receive timely vaccination. Similarly, affordability needs to be enhanced for influenza vaccination including better insurance coverage and reduced co-payment.

scholarly journals Prevalence and Predictors of Influenza Vaccination Among Adults with High-Risk Conditions, United States, 2019

2021 ◽  
Vol 2 (3) ◽  
pp. 137-145
Author(s):  
Saji Gopalan ◽  
Devi Mishra ◽  
Ashis Das
Keyword(s):  
United States ◽  
High Risk ◽  
Influenza Vaccination ◽  
Family Income ◽  
Influenza Infection ◽  
Insurance Coverage ◽  
Age Groups ◽  
The United States ◽  
Medical Conditions ◽  
To Receive

Introduction: Influenza could be associated with illnesses, severe complications, hospitalizations, and deaths among adults with high-risk medical conditions. Influenza vaccination reduces the risks and complications associated with influenza infection in high-risk conditions. We assessed the prevalence and predictors of influenza vaccination in a national sample of adults with high-risk medical conditions in the United States. Methods: Using the nationally representative National Health Interview Survey of 2019, we estimated the prevalence of influenza vaccination among adults with high-risk conditions. We tested the associations between receipt of vaccination and socio-demographic predictors. Results: Out of 15,258 adults with high-risk conditions, 56% reported receiving an influenza vaccine over the previous 12 months. Multivariable regressions show that respondents from older age groups, females, married, higher annual family income, having health insurance and those with more than two high-risk conditions are more likely to receive the vaccine. However, adults from non-Hispanic Black race/ethnicity and living in the Southern census region are less likely to receive the vaccination. Education levels and living in a metro show no associations with vaccination status. Conclusions: State authorities and providers have important roles in sensitizing and reminding individuals with high-risk conditions to receive timely vaccination. Affordability needs to be enhanced for influenza vaccination including better insurance coverage and reduced co-payment.

scholarly journals Seasonal Influenza Vaccine Effectiveness in People With Asthma: A National Test-Negative Design Case-Control Study

2019 ◽  
Vol 71 (7) ◽  
pp. e94-e104
Author(s):  
Eleftheria Vasileiou ◽  
Aziz Sheikh ◽  
Chris C Butler ◽  
Chris Robertson ◽  
Kimberley Kavanagh ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Case Control Study ◽  
Influenza Infection ◽  
Age Groups ◽  
Case Control ◽  
Vaccine Effectiveness ◽  
Vaccine Uptake ◽  
Individual Patient Level ◽  
Control Study

Abstract Background Influenza infection is a trigger of asthma attacks. Influenza vaccination can potentially reduce the incidence of influenza in people with asthma, but uptake remains persistently low, partially reflecting concerns about vaccine effectiveness (VE). Methods We conducted a test-negative designed case-control study to estimate the effectiveness of influenza vaccine in people with asthma in Scotland over 6 seasons (2010/2011 to 2015/2016). We used individual patient–level data from 223 practices, which yielded 1 830 772 patient-years of data that were linked with virological (n = 5910 swabs) data. Results Vaccination was associated with an overall 55.0% (95% confidence interval [CI], 45.8–62.7) risk reduction of laboratory-confirmed influenza infections in people with asthma over 6 seasons. There were substantial variations in VE between seasons, influenza strains, and age groups. The highest VE (76.1%; 95% CI, 55.6–87.1) was found in the 2010/2011 season, when the A(H1N1) strain dominated and there was a good antigenic vaccine match. High protection was observed against the A(H1N1) (eg, 2010/2011; 70.7%; 95% CI, 32.5–87.3) and B strains (eg, 2010/2011; 83.2%; 95% CI, 44.3–94.9), but there was lower protection for the A(H3N2) strain (eg, 2014/2015; 26.4%; 95% CI, −12.0 to 51.6). The highest VE against all viral strains was observed in adults aged 18–54 years (57.0%; 95% CI, 42.3–68.0). Conclusions Influenza vaccination gave meaningful protection against laboratory-confirmed influenza in people with asthma across all seasons. Strategies to boost influenza vaccine uptake have the potential to substantially reduce influenza-triggered asthma attacks.

scholarly journals A new look at influenza vaccination

2006 ◽  
Vol 27 (4) ◽  
pp. 175
Author(s):  
Victor Carey
Keyword(s):  
Public Health ◽  
High Risk ◽  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Health Benefits ◽  
Elderly Persons ◽  
Medical Conditions ◽  
Public Health Programmes ◽  
Health Programmes ◽  
New Look

Since the first influenza vaccine was licensed over 50 years ago, vaccination has consistently demonstrated its health benefits in preventing influenza and influenza vaccination is playing an increasingly important role in public health programmes in many countries. Individuals for whom vaccination is most commonly recommended include elderly persons over 65 years of age, persons with high risk medical conditions and children.

scholarly journals Influenza vaccine effectiveness among patients with high-risk medical conditions in the United States, 2012–2016

Vaccine ◽  
2018 ◽  
Vol 36 (52) ◽  
pp. 8047-8053 ◽  
Author(s):  
Mei Shang ◽  
Jessie R. Chung ◽  
Michael L. Jackson ◽  
Lisa A. Jackson ◽  
Arnold S. Monto ◽  
...  
Keyword(s):  
United States ◽  
High Risk ◽  
Influenza Vaccine ◽  
The United States ◽  
Vaccine Effectiveness ◽  
Medical Conditions

scholarly journals Influenza Vaccine Uptake and Associated Factors in Aged Care Facilities

2019 ◽  
Vol 34 (s1) ◽  
pp. s140-s140
Author(s):  
Mohana Kunasekaran ◽  
Mallory Trent ◽  
Elisa Lai ◽  
HaoYi Tan ◽  
Abrar Chughtai ◽  
...  
Keyword(s):  
High Risk ◽  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Aged Care ◽  
Vaccine Uptake ◽  
Care Staff ◽  
Age Related ◽  
Care Facilities ◽  
Aged Care Facilities ◽  
The Impact

Introduction:Influenza vaccine is recommended for high-risk populations in Australia (including those aged over 65 years) but is less effective in the elderly due to a progressive and predictable age-related decline in immune function, referred to as immunosenescence. Aged care facilities (ACF) are known to be at high risk of explosive outbreaks of influenza (even in highly vaccinated populations) and may reflect a higher intensity of transmission within the closed setting of ACF, as well as lower immunity and immunosenescence in the frail elderly.Methods:To measure the impact of influenza in aged-care staff (ACS) and residents as well as vaccine effectiveness, a prospective observational epidemiological study was conducted in collaboration with an aged-care provider with multiple sites from March to October 2018. Weekly active surveillance on influenza-like symptoms and questionnaires were used to collect data on two groups: ACS and residents. A range of variables was examined against their 2018 influenza vaccination status in statistical analysis.Results:Vaccination rates were high in residents and consistent with other studies. Vaccine rates in aged-care staff were lower and consistent with other studies.Discussion:Residents and relatives are unlikely to change their minds about vaccination from year to year unless there is targeted effort to persuade them to so, and negative perception of the vaccine is likely to persist. Workplace influenza vaccination programs targeted at staff could be an effective method of raising vaccine uptake.

The Effect of Influenza Vaccination History on Changes in Hemagglutination Inhibition Titers After Receipt of the 2015–2016 Influenza Vaccine in Older Adults in Hong Kong

2019 ◽  
Vol 221 (1) ◽  
pp. 33-41 ◽  
Author(s):  
Tiffany W Y Ng ◽  
Ranawaka A P M Perera ◽  
Vicky J Fang ◽  
Emily M Yau ◽  
J S Malik Peiris ◽  
...  
Keyword(s):  
Older Adults ◽  
Hong Kong ◽  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Hemagglutination Inhibition ◽  
Age Groups ◽  
Antibody Responses ◽  
Serum Samples ◽  
Vaccination History ◽  
Antibody Titers

Abstract Background Immune responses to influenza vaccination can be weaker in older adults than in other age groups. We hypothesized that antibody responses would be particularly weak among repeat vaccinees when the current and prior season vaccine components are the same. Methods An observational study was conducted among 827 older adults (aged ≥75 years) in Hong Kong. Serum samples were collected immediately before and 1 month after receipt of the 2015–2016 quadrivalent inactivated influenza vaccine. We measured antibody titers with the hemagglutination inhibition assay and compared the mean fold rise from prevaccination to postvaccination titers and the proportions with postvaccination titers ≥40 or ≥160. Results Participants who reported receipt of vaccination during either of the previous 2 years had a lower mean fold rise against all strains than with those who did not. Mean fold rises for A(H3N2) and B/Yamagata were particularly weak after repeated vaccination with the same vaccine strain, but we did not generally find significant differences in the proportions of participants with postvaccination titers ≥40 and ≥160. Conclusions Overall, we found that reduced antibody responses in repeat vaccinees were particularly reduced among older adults who had received vaccination against the same strains in preceding years.

scholarly journals Influenza Vaccination in Cancer Patients Undergoing Systemic Therapy

2014 ◽  
Vol 8 ◽  
pp. CMO.S13774 ◽  
Author(s):  
Mahmoud A. Shehata ◽  
Nagla Abdel Karim
Keyword(s):  
Adverse Effects ◽  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Cancer Patients ◽  
Clinical Outcomes ◽  
Influenza Infection ◽  
Immunological Response ◽  
Morbidity And Mortality ◽  
Serological Response ◽  
Patients With Cancer

Background Cancer patients often experience preventable infections, including influenza A and B. These infections can be a cause of significant morbidity and mortality. The increased risk of infection may be because of either cancer itself or treatment-induced immunosuppression. 1 Influenza immunization has been shown to decrease the risk of influenza infection in patients with intact immunity. 2 In cancer patients, active immunization has been shown to confer protective immunity against several infections at similar rates to healthy individuals, which has translated into decreased duration and severity of infection and potentially improved morbidity and mortality. 3 Objectives 1. To assess the efficacy of influenza vaccination in stimulating immunological response in patients with cancer during chemotherapy compared to control groups. 2. To assess the efficacy of influenza vaccination in preventing confirmed influenza and influenza-like illness and/or stimulating immunological response in children with cancer treated with chemotherapy, compared to placebo, no intervention, or different dosage schedules. 3. To determine the adverse effects associated with influenza vaccination in patients with cancer. Search Methods We searched MEDLINE/PubMed database for articles published from 1964 to 2013 using the search terms “cancer,” “adult,” “influenza vaccination,” and “chemotherapy.” Selection Criteria We included studies based on systematic sampling with defined clinical criteria irrespective of the vaccination status of cancer patients. Studies measure the serological response or clinical response to compare between the study group and the control group. Studies assessed the inactivated influenza vaccines and live attenuated influenza vaccine (LAIV) protective serological reaction and the clinical outcomes after vaccination. Data Collection and Analysis Two independent authors assessed the methodological quality of included studies and extracted data. Main Results We included 16 studies (total number of participants = 1,076). None of the included studies reported clinical outcomes. All included studies reported on influenza immunity and adverse reaction on vaccination. We included 6 solid tumor studies and 10 hematological studies. In 12 studies, the serological response to influenza vaccine was compared in patients receiving chemotherapy (n = 425) versus those not receiving chemotherapy (n = 376). In three studies, the serological responses to influenza vaccination in patients receiving chemotherapy are compared to that in healthy adult. Measures used to assess the serological responses included a four-fold rise increase in antibody titer development of hemagglutination inhibition (HI) titer >40, and pre- and post-vaccination geometric mean titers (GMTs). Immune responses in patients receiving chemotherapy were consistently weaker (four-fold rise of 17–52%) than in those who had completed chemotherapy (50–83%) and healthy patients (67–100%). Concerning adverse effects, oncology patients received influenza vaccine, and the side effects described were mild local reactions and low-grade fever. No life-threatening or persistent adverse effects were reported. Authors’ Conclusion Patients with solid and some of hematological tumors are able to mount a serological response to influenza vaccine, but it remains unclear how much this response protects them from influenza infection or its complications. Meanwhile, influenza vaccine appears to be safe in these patients. While waiting results of randomized controlled trials to give us more details about the clinical benefits of the influenza vaccination, the clinicians should consider the currently proved benefits of influenza vaccination on management of the cancer patients undergoing systematic chemotherapy such as decrease in the duration and severity of the of the disease, and significant decrease in influenza-associated morbidity and mortality in these high-risk patients. 3

Influenza vaccination coverage among children with high-risk medical conditions

Vaccine ◽  
2006 ◽  
Vol 24 (24) ◽  
pp. 5251-5255 ◽  
Author(s):  
Susanna Esposito ◽  
Paola Marchisio ◽  
Roberta Droghetti ◽  
Lara Lambertini ◽  
Nadia Faelli ◽  
...  
Keyword(s):  
High Risk ◽  
Influenza Vaccination ◽  
Vaccination Coverage ◽  
Medical Conditions

scholarly journals Influence of High‐Risk Medical Conditions on the Effectiveness of Influenza Vaccination among Elderly Members of 3 Large Managed‐Care Organizations

2002 ◽  
Vol 35 (4) ◽  
pp. 370-377 ◽  
Author(s):  
Eelko Hak ◽  
James Nordin ◽  
Feifei Wei ◽  
John Mullooly ◽  
Sung Poblete ◽  
...  
Keyword(s):  
High Risk ◽  
Managed Care ◽  
Influenza Vaccination ◽  
Medical Conditions ◽  
Managed Care Organizations

Impact of Severe Acute Respiratory Syndrome and the Perceived Avian Influenza Epidemic on the Increased Rate of Influenza Vaccination Among Nurses in Hong Kong

2008 ◽  
Vol 29 (3) ◽  
pp. 256-261 ◽  
Author(s):  
Dennise K. P. Tam ◽  
Shui-Shan Lee ◽  
Sing Lee
Keyword(s):  
Hong Kong ◽  
Avian Influenza ◽  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Influenza Infection ◽  
Vaccination Rate ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Major Barrier ◽  
Vaccination Rates

Objective.To determine the rate of influenza vaccination and the factors associated with the vaccination's acceptance among nurses in Hong Kong.Design.Cross-sectional survey.Participants.Nurses practicing between 2003 and 2007.Methods.A questionnaire was sent to all nurses registered with any of the 3 nursing associations that participated in this study.Results.A total of 941 completed questionnaires were available for analysis, though not all nurses responded to every question (response rate, 33.5%-36.3%). Vaccination rates in 2006 and 2007 were 57.2% and 46.2%, respectively. Nurses who were vaccinated in 2006 were more likely to get vaccinated in 2007 (P<.01); 56% of the nurses perceived influenza vaccine as being effective against influenza. The perceived effectiveness of influenza vaccine was a consistent predictor of rates of vaccination in 2006 (odds ratio [OR], 8.47 [95% confidence interval {CI}, 6.13-11.70];P<.01) and 2007 (OR, 6.05 [95% CI, 3.79-9.67];P<.01). Concern about contracting avian influenza was a predictor of the vaccination rate in 2006 but not in 2007 (OR, 1.47 [95% CI, 1.03-2.09];P<.05), as was the perceived lack of control over avian influenza infection (OR, 1.52 [95% CI, 1.06-2.18];P<.05).Conclusions.The overall influenza vaccination rate for nurses in Hong Kong was about 50%. It was affected by the perceived threat of an impending outbreak. The attitudes of nurses toward the effectiveness of and rationale for vaccination were a major barrier to increasing the rate of vaccination.

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