scholarly journals Objective adherence to an online FAVAS therapeutic game for treating amblyopia in children

2021 ◽  
Author(s):  
Catheline Bocqué ◽  
Jingyun Wang ◽  
Annekatrin Rickmann ◽  
Henrike Julich-Haertel ◽  
Uwe Kaempf ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Retrospective Study ◽  
Patient Adherence ◽  
Tablet Computer ◽  
Old Patients ◽  
Occlusion Therapy ◽  
Therapeutic Game ◽  
Recorded Data

ABSTRACTAimThis retrospective study was to evaluate whether an updated version of attention binding digital therapeutic games based on the principle of Focal Ambient Visual Acuity Stimulation (FAVAS) would result in an improved patient adherence of patching in 4- to 12-year-old patients with amblyopia.MethodsWe analyzed pseudonymised electronically recorded data from patients treated with two different versions of attention binding digital therapeutic games in 2015 and 2020. Two groups of children treated with occlusion therapy and attention binding digital therapeutic games, divided in treatment version, were compared. Patients in Group 2015 used the old version of therapeutic games without tablet computer functionality, while Group 2020 used more attractive therapeutic games with tablet computer functionality. Objective adherence was calculated by comparing the amount of minutes using the therapeutic games as monitored in the automatized logbook versus prescribed minutes of using the games.ResultsChildren in Group 2015 spent on average 2009.3±1372.1 (36 to 5472) minutes using FAVAS; children in Group 2020 spent on average 2695.5±1526.8 (37.5 to 5672) minutes using the improved therapy. Meaning, Group 2020 spent 686.2 more minutes on FAVAS than Group 2015 (t=3.87, P<0.001). Although patient adherence was very variable, it significantly improved up to 78% ± 46% in Group 2020 compared to the 57% ± 34% in Group 2015 (t=4.3, P<0.001).ConclusionFAVAS 2020 with an improved gamification aspect as well as tablet computer functionality increased adherence significantly compared to the earlier version FAVAS 2015, indicating that FAVAS 2020 could be an effective approach to support patching amblyopia treatment.

Does the gamification aspect of an online focal ambient visual acuity stimulation therapeutic game for treating amblyopia in children improve adherence? (Preprint)

2021 ◽  
Author(s):  
Catheline Bocqué ◽  
Jingyun Wang ◽  
Annekatrin Rickmann ◽  
Henrike Julich-Haertel ◽  
Uwe Kaempf ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Standard Treatment ◽  
Patient Adherence ◽  
Therapy Group ◽  
Tablet Computer ◽  
Old Patients ◽  
Occlusion Therapy ◽  
Therapeutic Game ◽  
Golden Standard ◽  
Recorded Data

BACKGROUND The golden standard treatment for amblyopia is patching the better eye. Visual acuity improvement of the amblyopic eye is significantly impacted by adherence of the patching therapy. It is known that the overall adherence is rather low. OBJECTIVE This retrospective study evaluated whether an updated version of attention binding digital therapeutic games based on the principle of focal ambient visual acuity stimulation (FAVAS) would result in an improved patient adherence in 4- to 16-year-old patients with amblyopia. METHODS We analyzed pseudonymised electronically recorded data from patients treated with occlusion therapy and FAVAS therapeutic games. One group used an older (2015) and the other group the newer version (2020) that provided more attractive therapeutic games with tablet computer functionality. Objective adherence was calculated by comparing the amount of minutes using the therapeutic games as monitored in the automatized logbook versus prescribed minutes of using the games. RESULTS Children in Group 2015 (n=138) spent on average 2009.3±1372.1 (36 to 5472) minutes using FAVAS; children in Group 2020 (n=129) spent on average 2695.5±1526.8 (37.5 to 5672) minutes using the improved therapy. Group 2020 spent on average 686.2 more minutes on FAVAS than Group 2015 (t=3.87, P<.001). Although patient adherence was very variable, compared to the 57%±34% in Group 2015, it significantly improved up to 78%±46% in Group 2020 (t=4.3, P<.001). CONCLUSIONS FAVAS 2020 with an improved gamification aspect as well as tablet computer functionality increased adherence significantly compared to the earlier version FAVAS 2015, indicating that FAVAS 2020 could be an effective approach to support adherence to amblyopia treatment. CLINICALTRIAL DRKS00017633

scholarly journals Corneal Higher-Order Aberrations after Microhook ab Interno Trabeculotomy and Goniotomy with the Kahook Dual Blade: Preliminary Early 3-Month Results

2021 ◽  
Vol 10 (18) ◽  
pp. 4115
Author(s):  
Hiromitsu Onoe ◽  
Kazuyuki Hirooka ◽  
Hideaki Okumichi ◽  
Yumiko Murakami ◽  
Yoshiaki Kiuchi
Keyword(s):  
Risk Factors ◽  
Visual Acuity ◽  
Retrospective Study ◽  
Cataract Surgery ◽  
Higher Order ◽  
Higher Order Aberrations ◽  
Postoperative Changes ◽  
The Mean ◽  
Kahook Dual Blade ◽  
Ab Interno

We examined postoperative corneal higher-order aberrations (HOAs) present after combined phacoemulsification with either microhook ab interno trabeculotomy (μLOT-Phaco) or goniotomy, using the Kahook Dual Blade (KDB-Phaco). Retrospective study: A total of 45 eyes underwent μLOT-Phaco and KDB-Phaco (LOT-Phaco) procedures, with 21 eyes that underwent cataract surgery alone used as controls. Visual acuity and corneal HOAs, coma-like aberrations, and spherical-like aberrations were analyzed before and at 1, 2, and 3 months after the surgeries. Risk factors that could potentially influence HOAs were evaluated. No significant postoperative changes were noted for corneal HOAs, coma-like aberrations, and spherical-like aberrations after cataract surgery alone. The mean corneal HOAs, coma-like aberrations, and spherical-like aberrations were 0.222 ± 0.115 μm, 0.203 ± 0.113 μm, and 0.084 ± 0.043 μm at baseline and 0.326 ± 0.195 μm (p < 0.001), 0.302 ± 0.289 μm (p = 0.03), and 0.150 ± 0.115 μm (p < 0.001) at 3 months after LOT-Phaco, respectively. Results of the analysis for risk factors suggested that a longer incision in Schlemm’s canal could influence corneal HOAs, coma-like aberrations, and spherical-like aberrations after LOT-Phaco. Although no significant postoperative changes were observed in corneal HOAs and coma-like or spherical-like aberrations after cataract surgery alone, a significant increase in corneal HOAs and coma-like or spherical-like aberrations remained after the LOT-Phaco procedure.

scholarly journals Cataract Surgery in Very Old Patients: A Case-Control Study

2021 ◽  
Vol 10 (20) ◽  
pp. 4658
Author(s):  
Hanan Nussinovitch ◽  
Erez Tsumi ◽  
Raimo Tuuminen ◽  
Boris Malyugin ◽  
Yotam Lior ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Cataract Surgery ◽  
Case Control Study ◽  
Surgical Techniques ◽  
Case Control ◽  
Dissipated Energy ◽  
Old Patients ◽  
Very Old ◽  
Very Old Patients ◽  
Control Study

Advancements in surgical techniques and increased life expectancy have made cataract surgery more common among very old patients. However, surgical outcomes seem impaired in patients older than 90 years, especially with ocular comorbidities. A retrospective case-control study of 53 eyes of 53 very old patients (mean 92.6 ± 3.0) and 140 eyes of 140 matched patients (mean 75.2 ± 7.6) was undertaken. Groups were matched in terms of gender and systemic and ocular comorbidities. In very old patients, higher phacoemulsification energy (cumulative dissipated energy [CDE], 25.0 ± 22.4 vs. 16.1 ± 10.7, p = 0.01) and rate of intraoperative floppy iris syndrome (IFIS, 9.4% vs. 1.4%, p = 0.02) were observed compared to controls. Uncorrected (UCVA) and best-corrected distance visual acuity (BCVA) gains were significantly poorer among the very old patients than among the control at postoperative day 30 (0.20 ± 0.70 vs. 0.56 ± 0.61 logMAR, p < 0.001 and 0.27 ± 0.64 vs. 0.55 ± 0.62 logMAR, p = 0.006, respectively). Even after including CDE and IFIS as covariates, age remained an independent factor for poor visual gain at 30 days (p < 0.001). Cataract surgery in very old patients may demand more experienced surgeons due to higher nuclear density and the rates of IFIS. Expectations in visual acuity gains should be aligned with the patient’s age.

scholarly journals Association Between Occlusion Therapy and Optotype Visual Acuity in Children Using Data From the Infant Aphakia Treatment Study

2016 ◽  
Vol 134 (8) ◽  
pp. 863 ◽  
Author(s):  
Carolyn Drews-Botsch ◽  
Marianne Celano ◽  
George Cotsonis ◽  
E. Eugenie Hartmann ◽  
Scott R. Lambert ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Occlusion Therapy ◽  
Using Data

scholarly journals Biomechanical and Refractive Results of Transepithelial Cross-linking Treatment in Keratoconic Eyes

2012 ◽  
Vol 1 (2) ◽  
pp. 75-78 ◽  
Author(s):  
Cynthia J Roberts
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Retrospective Study ◽  
Resistance Factor ◽  
Ocular Response Analyzer ◽  
Cross Linking ◽  
Short Term ◽  
Refractive Outcomes ◽  
Signal Value ◽  
Signal Peak

ABSTRACT Purpose To analyze change in visual acuity (VA), refractive outcomes, corneal compensated intraocular pressure (IOPcc), corneal hysteresis (CH) and cornea resistance factor (CRF) after transepithelial cross-linking (CXL) treatment. Setting Kudret Eye Hospital, Ankara, Turkey Materials and methods A total of 32 eyes of 22 patients diagnosed with keratoconus were included in this retrospective study. Changes in VA, spheric and cylinderic refraction for all eyes were analyzed before and 3 months after transepithelial CXL. In addition, a subset of 14 eyes had data acquired using the ocular response analyzer (ORA), and for these eyes, IOPcc, CH and CRF were recorded as well as a measurement of the amplitude of the first peak in the infrared signal (peak 1), used to identify the inward applanation event. The ORA parameters were also compared before and 3 months after treatment. Results Uncorrected and best corrected VA increased 1.76 and 1.61 Snellen lines (p < 0.05); spheric and cylinderic refractions improved 0.74 and 0.43 D (p > 0.05) respectively. Mean changes in IOPcc, CRF and CH were not significantly different (p > 0.05). However, mean peak 1 signal value increased significantly (p < 0.05). Conclusion Transepithelial CXL is effective in VA improvement in the short-term with an increase in the peak 1 signal value which is consistent with an increase in stiffness of cornea, whereas IOPcc, CRF and CH values remained the same. How to cite this article Klllç A, Roberts CJ. Biomechanical and Refractive Results of Transepithelial Cross-linking Treatment in Keratoconic Eyes. Int J Kerat Ect Cor Dis 2012;1(2):75-78.

scholarly journals Natural Course and Prognostic Factors of Ethambutol Toxic Optic Neuropathy

2020 ◽  
Author(s):  
Ye Ji Kim ◽  
Soo Hyun Lim ◽  
Ungsoo Kim
Keyword(s):  
Visual Acuity ◽  
Prognostic Factors ◽  
Optic Neuropathy ◽  
Natural Course ◽  
Systemic Diseases ◽  
Old Patients ◽  
Toxic Optic Neuropathy ◽  
Initial Visual Acuity ◽  
Risk Patients ◽  
Recovery Group

Abstract Background: To investigate the natural course and prognostic factors of ethambutol toxic optic neuropathy (ETON).Methods: Medical charts of 87 patients diagnosed with ETON were reviewed retrospectively, and the visual acuity and history of ethambutol medication were analyzed. Based on the final visual acuity, patients were divided into two groups: recovery and no-recovery groups. We investigated the prognostic factors, including the sex, age, duration of medication, initial visual acuity, and systemic diseases (diabetes mellitus, hypertension, renal disorders, etc.). Results: In this study, 37 men and 50 women, with ages ranging from 22 to 91 years, were included. Although a poor initial visual acuity was noted in the old patients, a short duration of medication had a weak negative correlation with the initial visual acuity. Follow-up of over 1 year could be performed for 28 out of 87 patients, including nine men and 19 women, with a mean age of 70.0 ± 8.2 years. Ten eyes of seven (25%) patients, including three men and four women, did not recover vision after discontinuation of ethambutol. Patients were significantly older in the no-recovery group than in the recovery group (73.9 ± 8.3 and 68.7 ± 8.1 years, respectively). The poor initial visual acuity and presence of systemic diseases affected the prognosis of ETON. Conclusion: Three-fourth of patients with ETON had visual recovery after discontinuation of ethambutol. High-risk patients with poor prognostic factors, including old age, presence of systemic diseases, and poor initial visual acuity, should be screened in early stages of ETON.

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