scholarly journals Cortical compensation for hearing loss, but not age, in neural tracking of the fundamental frequency of the voice

2021 ◽  
Author(s):  
Jana Van Canneyt ◽  
Jan Wouters ◽  
Tom Francart
Keyword(s):  
Hearing Loss ◽  
Fundamental Frequency ◽  
Auditory Processing ◽  
Phase Locking ◽  
Normal Hearing ◽  
Hearing Impaired ◽  
Cortical Response ◽  
Age Related ◽  
Underlying Mechanisms ◽  
The Voice

AbstractAuditory processing is affected by advancing age and hearing loss, but the underlying mechanisms are still unclear. We investigated the effects of age and hearing loss on temporal processing of naturalistic stimuli in the auditory system. We analysed neural phase-locking to the fundamental frequency of the voice (f0) in 54 normal-hearing and 14 hearing-impaired adults between 17 and 82 years old. We found that both subcortical and cortical neural sources contributed to the responses. Results indicated that advancing age was related to smaller responses with less cortical response contributions, consistent with an age-related decrease in neural phase-locking ability. Conversely, hearing impaired subjects displayed larger responses compared to age-matched normal hearing controls. This was due to additional cortical response contributions which were stronger for participants with more severe hearing loss. This is consistent with the recruitment of additional cortical sources for auditory processing in persons with hearing impairment.

scholarly journals Cortical compensation for hearing loss, but not age, in neural tracking of the fundamental frequency of the voice

2021 ◽  
Author(s):  
Jana Van Canneyt ◽  
Jan Wouters ◽  
Tom Francart
Keyword(s):  
Hearing Loss ◽  
Fundamental Frequency ◽  
Auditory System ◽  
Phase Locking ◽  
Normal Hearing ◽  
Hearing Impaired ◽  
Cortical Response ◽  
Age Related ◽  
Latency Range ◽  
The Voice

Auditory processing is affected by advancing age and hearing loss, but the underlying mechanisms are still unclear. We investigated the effects of age and hearing loss on temporal processing of naturalistic stimuli in the auditory system. We employed a recently developed objective measure for neural phase-locking to the fundamental frequency of the voice (f0) which uses continuous natural speech as a stimulus, i.e. 'f0 tracking'. F0-tracking responses from 54 normal hearing and 14 hearing impaired adults of varying ages were analysed. The responses were evoked by a Flemish story with a male talker and contained contributions from both subcortical and cortical sources. Results indicated that advancing age was related to smaller responses with less cortical response contributions. This is consistent with an age-related decrease in neural phase-locking ability at frequencies in the range of the f0, possibly due to decreased inhibition in the auditory system. Conversely, hearing impaired subjects displayed larger responses compared to age-matched normal hearing controls. This was due to additional cortical response contributions in the 38-50 ms latency range, which were stronger for participants with more severe hearing loss. This is consistent with hearing-loss induced cortical reorganisation and recruitment of additional neural resources to aid in speech perception.

Older Listeners' Use of Temporal Cues Altered by Compression Amplification

2000 ◽  
Vol 43 (3) ◽  
pp. 661-674 ◽  
Author(s):  
Pamela E. Souza
Keyword(s):  
Hearing Loss ◽  
Hearing Aids ◽  
High Frequency ◽  
Dynamic Range ◽  
Normal Hearing ◽  
Hearing Impaired ◽  
Temporal Information ◽  
Spectral Information ◽  
Temporal Cues ◽  
Age Related

This study compared the ability of younger and older listeners to use temporal information in speech when that information was altered by compression amplification. Recognition of vowel-consonant-vowel syllables was measured for four groups of adult listeners (younger normal hearing, older normal hearing, younger hearing impaired, older hearing impaired). There were four conditions. Syllables were processed with wide-dynamic range compression (WDRC) amplification and with linear amplification. In each of those conditions, recognition was measured for syllables containing only temporal information and for syllables containing spectral and temporal information. Recognition of WDRC-amplified speech provided an estimate of the ability to use altered amplitude envelope cues. Syllables were presented with a high-frequency masker to minimize confounding differences in high-frequency sensitivity between the younger and older groups. Scores were lower for WDRC-amplified speech than for linearly amplified speech, and older listeners performed more poorly than younger listeners. When spectral information was unrestricted, the age-related decrement was similar for both amplification types. When spectral information was restricted for listeners with normal hearing, the age-related decrement was greater for WDRC-amplified speech than for linearly amplified speech. When spectral information was restricted for listeners with hearing loss, the age-related decrement was similar for both amplification types. Clinically, these results imply that when spectral cues are available (i.e., when the listener has adequate spectral resolution) older listeners can use WDRC hearing aids to the same extent as younger listeners. For older listeners without hearing loss, poorer scores for compression-amplified speech suggest an age-related deficit in temporal resolution.

Speech Identification Difficulties of Hearing-Impaired Elderly Persons

1991 ◽  
Vol 34 (3) ◽  
pp. 686-693 ◽  
Author(s):  
Larry E. Humes ◽  
Laurel Christopherson
Keyword(s):  
Hearing Loss ◽  
Auditory Processing ◽  
The Elderly ◽  
Normal Hearing ◽  
Hearing Impaired ◽  
Elderly Subjects ◽  
Elderly Persons ◽  
Identification Score ◽  
Masking Noise ◽  
Speech Identification

This study examined the performance of four subject groups on several temporally based measures of auditory processing and several measures of speech identification. The four subject groups were (a) young normal-hearing adults; (b) hearing-impaired elderly subjects ranging in age from 65 to 75 years; (c) hearing-impaired elderly adults ranging in age from 76 to 86 years; and (d) young normal-hearing listeners with hearing loss simulated with a spectrally shaped masking noise adjusted to match the actual hearing loss of the two elderly groups. In addition to between-group analyses of performance on the auditory processing and speech identification tasks, correlational and regression analyses within the two groups of elderly hearing-impaired listeners were performed. The results revealed that the threshold elevation accompanying sensorineural hearing loss was the primary factor affecting the speech identification performance of the hearing-impaired elderly subjects both as groups and as individuals. However, significant increases in the proportion of speech identification score variance accounted for were obtained in the elderly subjects by including various measures of auditory processing.

scholarly journals Auditory processing abilities in pitch and duration pattern tests for elderly:

2021 ◽  
Vol 33 (3) ◽  
pp. 447-461
Author(s):  
Debora Bonizio Zukowski ◽  
Sheila Andreoli Balen ◽  
Karinna Veríssimo Meira Taveira ◽  
Isabella Monteiro de Castro Silva ◽  
Lucas Moura Viana ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hearing Loss ◽  
Elderly People ◽  
Auditory Processing ◽  
Grey Literature ◽  
Normal Hearing ◽  
Research Strategy ◽  
Cross Sectional ◽  
Age Related ◽  
Pattern Sequence

Purpose: to analyze the performance of elderly people with hearing loss compared to normal-hearing elderly people in the Pitch Pattern Sequence Test (PPS) and Duration Pattern Sequence Test (DPS). Research strategy: Electronic search strategies were individually developed for each of the following databases: LILACS, LIVIVO, Pubmed, Scopus, SpeechBITE and Web of Science. Grey literature was searched by using Google Scholar, OpenGrey and Proquest Dissertations and Theses. Selection criteria: Observational studies that evaluated elderly (over 60 years old) with age related hearing loss or presbycusis, ranging from mild to moderately severe, with different scores, compared to normal hearing for pitch (PPS) or duration pattern sequence (DPS) tests were included. The methodology of selected studies was evaluated using Meta-Analysis of Statistics Assessment and Review Instrument (MAStARI) critical appraisal tools for cross sectional studies. No restrictions regarding language, period of publication or gender were applied. Results: Title and summary of 1042 articles were analyzed after duplicates were removed. From this analysis, the full texts of 15 articles were analyzed. Five studies were included in this systematic review, three studies used the Musiek DPS version, two used the Auditec DPS and PPS version. Risk of bias was low (three studies) and moderate (two studies), according to this protocol. Conclusion: This systematic review showed no score differences between groups with presbycusis compared with normal hearing for DPS and PPS test. More primary studies utilizing the same protocol for PPS and DPS are needed.

scholarly journals Identification of the Spectrotemporal Modulations That Support Speech Intelligibility in Hearing-Impaired and Normal-Hearing Listeners

2019 ◽  
Vol 62 (4) ◽  
pp. 1051-1067 ◽  
Author(s):  
Jonathan H. Venezia ◽  
Allison-Graham Martin ◽  
Gregory Hickok ◽  
Virginia M. Richards
Keyword(s):  
Hearing Loss ◽  
Speech Recognition ◽  
Speech Intelligibility ◽  
Large Scale ◽  
Recognition Performance ◽  
Recognition Task ◽  
Small Region ◽  
Normal Hearing ◽  
Hearing Impaired ◽  
Age Related

Purpose Age-related sensorineural hearing loss can dramatically affect speech recognition performance due to reduced audibility and suprathreshold distortion of spectrotemporal information. Normal aging produces changes within the central auditory system that impose further distortions. The goal of this study was to characterize the effects of aging and hearing loss on perceptual representations of speech. Method We asked whether speech intelligibility is supported by different patterns of spectrotemporal modulations (STMs) in older listeners compared to young normal-hearing listeners. We recruited 3 groups of participants: 20 older hearing-impaired (OHI) listeners, 19 age-matched normal-hearing listeners, and 10 young normal-hearing (YNH) listeners. Listeners performed a speech recognition task in which randomly selected regions of the speech STM spectrum were revealed from trial to trial. The overall amount of STM information was varied using an up–down staircase to hold performance at 50% correct. Ordinal regression was used to estimate weights showing which regions of the STM spectrum were associated with good performance (a “classification image” or CImg). Results The results indicated that (a) large-scale CImg patterns did not differ between the 3 groups; (b) weights in a small region of the CImg decreased systematically as hearing loss increased; (c) CImgs were also nonsystematically distorted in OHI listeners, and the magnitude of this distortion predicted speech recognition performance even after accounting for audibility; and (d) YNH listeners performed better overall than the older groups. Conclusion We conclude that OHI/older normal-hearing listeners rely on the same speech STMs as YNH listeners but encode this information less efficiently. Supplemental Material https://doi.org/10.23641/asha.7859981

scholarly journals IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss

Cells ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1686
Author(s):  
Adelaida M. Celaya ◽  
Lourdes Rodríguez-de la Rosa ◽  
Jose M. Bermúdez-Muñoz ◽  
José M. Zubeldia ◽  
Carlos Romá-Mateo ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Inflammatory Cytokines ◽  
Noise Exposure ◽  
Sensorineural Deafness ◽  
Serum Levels ◽  
Genetic Syndromes ◽  
Expression Ratio ◽  
Postnatal Maturation ◽  
Age Related ◽  
Underlying Mechanisms

Insulin-like growth factor 1 (IGF-1) deficiency is an ultrarare syndromic human sensorineural deafness. Accordingly, IGF-1 is essential for the postnatal maturation of the cochlea and the correct wiring of hearing in mice. Less severe decreases in human IGF-1 levels have been associated with other hearing loss rare genetic syndromes, as well as with age-related hearing loss (ARHL). However, the underlying mechanisms linking IGF-1 haploinsufficiency with auditory pathology and ARHL have not been studied. Igf1-heterozygous mice express less Igf1 transcription and have 40% lower IGF-1 serum levels than wild-type mice. Along with ageing, IGF-1 levels decreased concomitantly with the increased expression of inflammatory cytokines, Tgfb1 and Il1b, but there was no associated hearing loss. However, noise exposure of these mice caused increased injury to sensory hair cells and irreversible hearing loss. Concomitantly, there was a significant alteration in the expression ratio of pro- and anti-inflammatory cytokines in Igf1+/− mice. Unbalanced inflammation led to the activation of the stress kinase JNK and the failure to activate AKT. Our data show that IGF-1 haploinsufficiency causes a chronic subclinical proinflammatory age-associated state and, consequently, greater susceptibility to stressors. This work provides the molecular bases to further understand hearing disorders linked to IGF-1 deficiency.

scholarly journals Perception of Auditory Distance in Normal-Hearing and Moderate-to-Profound Hearing-Impaired Listeners

2019 ◽  
Vol 23 ◽  
pp. 233121651988761 ◽  
Author(s):  
Gilles Courtois ◽  
Vincent Grimaldi ◽  
Hervé Lissek ◽  
Philippe Estoppey ◽  
Eleftheria Georganti
Keyword(s):  
Hearing Loss ◽  
Hearing Aids ◽  
Normal Hearing ◽  
Hearing Impaired ◽  
Spatial Cues ◽  
Linear Amplification ◽  
Profound Hearing Loss ◽  
Wireless Microphone ◽  
Auditory Distance ◽  
Non Linear

The auditory system allows the estimation of the distance to sound-emitting objects using multiple spatial cues. In virtual acoustics over headphones, a prerequisite to render auditory distance impression is sound externalization, which denotes the perception of synthesized stimuli outside of the head. Prior studies have found that listeners with mild-to-moderate hearing loss are able to perceive auditory distance and are sensitive to externalization. However, this ability may be degraded by certain factors, such as non-linear amplification in hearing aids or the use of a remote wireless microphone. In this study, 10 normal-hearing and 20 moderate-to-profound hearing-impaired listeners were instructed to estimate the distance of stimuli processed with different methods yielding various perceived auditory distances in the vicinity of the listeners. Two different configurations of non-linear amplification were implemented, and a novel feature aiming to restore a sense of distance in wireless microphone systems was tested. The results showed that the hearing-impaired listeners, even those with a profound hearing loss, were able to discriminate nearby and far sounds that were equalized in level. Their perception of auditory distance was however more contracted than in normal-hearing listeners. Non-linear amplification was found to distort the original spatial cues, but no adverse effect on the ratings of auditory distance was evident. Finally, it was shown that the novel feature was successful in allowing the hearing-impaired participants to perceive externalized sounds with wireless microphone systems.

AGE-RELATED ISSUES OF THE QUALITY OF LIFE IN HEARING IMPAIRED PATIENTS

2021 ◽  
pp. 885-892
Author(s):  
Л. Е. Голованова ◽  
Е. А. Огородникова ◽  
Е. С. Лаптева ◽  
М. Ю. Бобошко
Keyword(s):  
Quality Of Life ◽  
Hearing Loss ◽  
Hearing Aids ◽  
Pure Tone Audiometry ◽  
Hearing Impaired ◽  
Hearing Disorders ◽  
Age Related ◽  
Sf 36 ◽  
Significant Difference

Целью исследования было изучение качества жизни лиц с нарушениями слуха в разных возрастных группах. Обследованы 100 пациентов, обратившихся в городской сурдологический центр для взрослых в связи с нарушением слуха: 50 человек - 34-59 лет, 50 - 60 лет и старше, из которых 32 человека были пожилого возраста (60-74 года)и 18 - старческого (75-86 лет). Степень тугоухости оценивали на основании результатов тональной пороговой аудиометрии. Для исследования качества жизни все пациенты заполняли общий опросник MOS SF-36, отражающий физический и психологический компоненты здоровья, а также специальный опросник HHIА(E)-S для лиц с нарушениями слуха. Установлено, что шкала HHIА(E)-S демонстрирует высокую корреляцию со степенью тугоухости у пациентов моложе 60 лет ( R =0,98; достоверность различий на уровне p <0,05), которая снижается у пациентов 60 лет и старше ( R =0,94; различия в оценках при разной степени тугоухости недостоверны). Значительные трудности в старшей возрастной группе могут быть связаны с тем, что людям пожилого и, особенно, старческого возраста сложно пользоваться слуховыми аппаратами (или они для них неэффективны) и оценивать свои затруднения по шкалам опросника. Целесообразно использовать шкалу HHIА(Е)-S в качестве скринингового инструмента для раннего выявления тугоухости, направления пациентов к сурдологу и своевременного слухопротезирования. The aim of the research was to study the quality of life in hearing impaired patients of different age. 100 patients referred to the city audiology centre because of their hearing disorders were examined: 50 patients from 34 to 59 years old and 50 patients from 60 years and older, from which 32 patients were of older age (60 to 74 years old) and 18 of oldest age (75 to 86 years old). A degree of hearing loss was assessed according to results of pure tone audiometry. To study the quality of life all patients filled in the questionnaire MOS SF-36, which evaluates physical and psychological components of health, and the questionnaire HHIA(E)-S, designed specifically for patients with hearing disorders. The HHIA(E)-S scale was found to show high correlation with hearing loss degree in patients younger than 60 years old ( R =0,98 with statistically significant difference, p <0,05), with decreasing correlation in patients from 60 years and older ( R =0,98; no significant difference while assessing various hearing loss degrees). Considerable difficulties in this age group may be explained by the fact, that older and especially oldest patients have a challenge with hearing aids usage (or they are of low efficiency for them) and with assessing theirs difficulties on the questionnaire scales. The HHIA(E)-S scale is useful as a screening tool for early detection of hearing loss, referral of patients to an audiologist and prompt hearing aid fitting.

Effect of Age on Prediction of Hearing Loss with the Bivariate-Plotting Procedure

1984 ◽  
Vol 27 (1) ◽  
pp. 12-19 ◽  
Author(s):  
Shlomo Silman ◽  
Carol Ann Silverman ◽  
Theresa Showers ◽  
Stanley A. Gelfand
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Predictive Accuracy ◽  
Normal Hearing ◽  
Hearing Impaired ◽  
Sensorineural Hearing ◽  
Line Segments ◽  
Bivariate Plot ◽  
Accuracy Of Prediction ◽  
Effect Of Age

The effect of age on accuracy of prediction of hearing impairment with the bivariate-plotting procedure was investigated in 72 normal-hearing subjects aged 20–69 years and in 86 sensorineural hearing-impaired subjects aged 20–83 years. The predictive accuracy with the bivariate-plotting procedure improved markedly when the data from subjects over 44 years of age were excluded from the bivariate plot. The predictive accuracy improved further when the construction of the line segments in the traditional bivariate plot was modified.

Role of Fundamental Frequency Differences in the Perceptual Separation of Competing Vowel Sounds by Listeners With Normal Hearing and Listeners With Hearing Loss

1997 ◽  
Vol 40 (6) ◽  
pp. 1434-1444 ◽  
Author(s):  
Kathryn Hoberg Arehart ◽  
Catherine Arriaga King ◽  
Kelly S. McLean-Mudgett
Keyword(s):  
Hearing Loss ◽  
Fundamental Frequency ◽  
Normal Hearing ◽  
Average Increase ◽  
Identification Task ◽  
Vowel Identification ◽  
Overall Performance ◽  
The Mean ◽  
Perceptual Separation

This study compared the ability of listeners with normal hearing and listeners with moderate to moderately-severe sensorineural hearing loss to use fundamental frequency differences (ΔF 0 ) in the identification of monotically presented simultaneous vowels. Two psychophysical procedures, double vowel identification and masked vowel identification, were used to measure identification performance as a function of ΔF 0 (0 through 8 semitones) between simultaneous vowels. Performance in the double vowel identification task was measured by the percentage of trials in which listeners correctly identified both vowels in a double vowel. The masked vowel identification task yielded thresholds representing signal-to-noise ratios at which listeners could just identify target vowels in the presence of a masking vowel. In the double vowel identification task, both listeners with normal hearing and listeners with hearing loss showed significant ΔF 0 benefit: Between 0 and 2 semitones, listeners with normal hearing showed an 18.5% average increase in performance; listeners with hearing loss showed a 16.5% average increase. In the masked vowel identification task, both groups showed significant ΔF 0 benefit. However, the mean benefit associated with ΔF 0 differences in the masked vowel task was more than twice as large in listeners with normal hearing 9.4 dB) when compared to listeners with hearing loss (4.4 dB), suggesting less ΔF 0 benefit in listeners with hearing loss. In both tasks, overall performance of listeners with hearing loss was significantly worse than performance of listeners with normal hearing. Possible reasons for reduced ΔF 0 benefit and decreased overall performance in listeners with hearing loss include reduced audibility of vowel sounds and deficits in spectro-temporal processing.

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