scholarly journals A Study On Clinical Profile And Semiology In Complex Partial Seizures And Its Radiological Correlation

2021 ◽  
Author(s):  
Nandini Priyanka Balasubramani ◽  
Elangovan S ◽  
Thangaraj M
Keyword(s):  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Epileptic Seizures ◽  
Complex Partial Seizure ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Clinical Profile ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Cross Sectional

Background: Epilepsy is the second most common and frequently encountered neurological disorder which poses huge threat to known healthcare systems worldwide also causing financial, socio economic burden to the community. Complex Partial Seizures are a form of focal epileptic seizures that may impair consciousness. Aim and objectives: Our motivation for the study was to understand the extent of patients with complex partial seizures associated with medial temporal lobe sclerosis. Materials and methods: We performed a cross sectional study about patients with complex partial seizures in Thanjavur medical college and hospital about their clinical profile and neuro-radiological correlation. Statistical analysis and results: Through our multimodal study with EEG, MRI on N=118 (female / male, age range, Most common age group- 10-20 years, mean age of 23 years, SD- 14 years, 66% males), we observed that atypical febrile seizures and fever provoked seizures has more association (18%) to complex partial seizures and to medial temporal lobe sclerosis in comparison to 12% in an earlier study. Conclusion: We believe this study summarizes the complex partial seizure features, origin, and their link to Medial Temporal lobe Sclerosis in our subject pool from Thajavur, India. Limitation: There are some limitations to our study, especially with no video EEG monitoring and no invasive EEG recording. We aim to improve them in our future studies.

scholarly journals Clinico-Demographic Characteristics and Different Diagnostic Findings of Epilepsy Patients in a Specialized Hospital Outside Dhaka in Bangladesh

2017 ◽  
Vol 2 (1) ◽  
pp. 3-9
Author(s):  
Abdus Salam ◽  
Md Ruhul Quddus ◽  
Md Sayedur Rahman Sheikh ◽  
Md Arshad-ul Azim ◽  
Mohammad Enayet Hussain
Keyword(s):  
Complex Partial Seizure ◽  
Cross Sectional Study ◽  
Demographic Characteristics ◽  
Social Classes ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Cross Sectional ◽  
Specialized Hospital ◽  
Different Types ◽  
Neurological Conditions

Background: Epilepsy is a common neurological conditions. It is a global problem affecting all ages, social classes, groups and countries. Objective: The purpose of the present study was to see the clinico-demographic characteristics and different diagnostic findings of epilepsy patients. Methodology: This cross sectional study was carried out in the Department of Neurology at Shaheed Sheikh Abu Naser Specialized Hospital, Khulna, Bangladesh from November, 2012 to February, 2014. The patients were recruited from the epilepsy clinic. Clinical diagnosis of epilepsy was made by meticulous history and relevant clinical examination by the investigator. Routinely electroencephalography (EEG) was advised and interpreted by the investigator and MRI was advised in appropriate cases.Results: A total number of 115 epilepsy patients were recruited of which 77(67.0%) were male and 38(33.0%) were female. Most [95(83.7%)] of the patients were young (age group 0 to 29 years) and had partial seizures 89 (77.39%). Among these partial seizures most had complex partial seizure (CPS) [82(71.3%)] of which 53 (46.1%) had complex partial seizures-Temporal (CPS-T) and 29 (25.2%) had complex partialseizures-extra-temporal (CPS-ET) origin. EEG could be done in 76 patients. Among them 37(48.7%) had different types of abnormalities. MRI could be done in 52 patients and were found to be abnormal in 32(61.5%) patients.Conclusion: This study revealed that localization related epilepsy (LRE) is more common but the etiology remains undetermined in many cases. Therefore, more effort and investigation facilities are needed to identify the etiology. The high number of extra temporal lobe epilepsy (Ex-TLE) needs further evaluation in bigger sample.Journal of National Institute of Neurosciences Bangladesh, 2016;2(1): 3-9

scholarly journals Is Prolactin a Clinically Useful Measure of Epilepsy?

2006 ◽  
Vol 6 (3) ◽  
pp. 78-79 ◽  
Author(s):  
Elinor Ben-Menachem
Keyword(s):  
Status Epilepticus ◽  
Elevated Serum ◽  
Epileptic Seizures ◽  
Complex Partial Seizure ◽  
Class Ii ◽  
Serum Prolactin ◽  
Tilt Test ◽  
Neonatal Seizures ◽  
Partial Seizures ◽  
Complex Partial Seizures

Use of Serum Prolactin in Diagnosing Epileptic Seizures: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology Chen DK, So YT, Fisher RS Neurology 2005;65(5):668–675 (Review) Objective The purpose of this article is to review the use of serum prolactin assay in epileptic seizure diagnosis. Methods The authors identified relevant studies in multiple databases and reference lists. Studies that met inclusion criteria were summarized and rated for quality of evidence, and the results were analyzed and pooled where appropriate. Results Most studies used a serum prolactin of at least twice baseline value as abnormal. For the differentiation of epileptic seizures from psychogenic nonepileptic seizures, one Class I and seven Class II studies showed that elevated serum prolactin was highly predictive of either generalized tonic–clonic or complex partial seizures. Pooled sensitivity was higher for generalized tonic–clonic seizures (60.0%) than for complex partial seizures (46.1%), while the pooled specificity was similar for both (approximately 96%). Data were insufficient to establish validity for simple partial seizures. Two Class II studies were consistent in showing prolactin elevation after tilt-test–induced syncope. Inconclusive data exist regarding the value of serum prolactin following status epilepticus, repetitive seizures, and neonatal seizures. Recommendations Elevated serum prolactin assay, when measured in the appropriate clinical setting at 10 to 20 minutes after a suspected event, is a useful adjunct for the differentiation of generalized tonic–clonic or complex partial seizure from psychogenic nonepileptic seizure among adults and older children (Level B). Serum prolactin assay does not distinguish epileptic seizures from syncope (Level B). The use of serum PRL assay has not been established in the evaluation of status epilepticus, repetitive seizures, and neonatal seizures (Level U).

scholarly journals Temporal choroidal fissure cyst and temporal lobe epilepsy: report of two cases

2010 ◽  
Vol 16 (4) ◽  
pp. 167-169 ◽  
Author(s):  
Gustavo Rassier Isolan ◽  
Marino Muxfeldt Bianchin ◽  
Carolina Machado Torres ◽  
José Augusto Bragatti ◽  
Juliana Bohn Assman ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Temporal Lobe ◽  
Clinical Course ◽  
Case Reports ◽  
Complex Partial Seizure ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Temporal Horn ◽  
Background Data ◽  
Temporal Lobe Seizure

STUDY DESIGN: Two case reports of a choroidal fissure cyst in the temporal horn associated with complex partial seizure. OBJECTIVES: To describe the clinical course, image findings and literature review of choroidal fissure cysts. SUMMARY AND BACKGROUND DATA: there are few reported cases of choroidal fissure cysts. RESULTS: We report two patients with complex partial seizures and temporal choroidal fissure cysts. The seizures were controlled in both patients. CONCLUSION: The choroidal fissure cyst diagnosis must highlight the importance of considering this lesion in the differential diagnosis of temporal lobe cyst and temporal lobe seizure.

scholarly journals Association between Self-Reported Pain, Cognition, and Neuropathology in Older Adults Admitted to an Outpatient Memory Clinic—A Cross-Sectional Study

2021 ◽  
Vol 11 (9) ◽  
pp. 1156
Author(s):  
Víctor I. Madariaga ◽  
Eduard Overdorp ◽  
Jurgen A. H. R. Claassen ◽  
Inti A. Brazil ◽  
Joukje M. Oosterman
Keyword(s):  
Depressive Symptoms ◽  
White Matter ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Cross Sectional Study ◽  
Memory Clinic ◽  
Cross Sectional ◽  
Clinical Diagnoses ◽  
Lower Pain ◽  
Affective Components

Cognitive impairment has been linked to reduced self-reporting of pain. However, it is unclear whether the various cognitive functions are similarly and/or independently associated with such pain report measures. In the present study, we explored how executive functioning (EF), memory, and global cognition relate to self-reported pain and investigated whether underlying neuropathology partially accounts for these results. We used Lasso categorical regression to analyze data from 179 individuals visiting a memory clinic. The data included the self-reported pain occurrence, intensity, severity and frequency, clinical diagnoses, neuropsychological scores, white matter hyperintensities, medial temporal lobe atrophy, depressive symptoms, and demographics. Our results showed that worse memory and EF performance predicted a lower pain occurrence. In those individuals who did report pain, worse memory predicted lower pain intensity, severity, and frequency levels, but for EF reversed effects were found, with worse EF predicting higher pain scores. These relationships were only partially explained by reductions in white matter and medial temporal lobe integrity. Similar effects were found for depressive symptoms. Our findings highlight the distinct associations of EF and memory with self-reported pain. A similar pattern of relationships found for both self-reported pain and depressive symptoms may reflect shared latent affective components.

scholarly journals Assessment of Saudi Parents’ Beliefs and Behaviors towards Management of Child Fever in Saudi Arabia—A Cross-Sectional Study

2021 ◽  
Vol 18 (10) ◽  
pp. 5217
Author(s):  
Mohamed N. Al Arifi ◽  
Abdulrahman Alwhaibi
Keyword(s):  
Saudi Arabia ◽  
Side Effects ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Inclusion Criteria ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Electronic Thermometer ◽  
And Behavior

Objective: Fever alone can lead to rare serious complications in children, such as febrile seizures. The aim of this study is to assess the knowledge, beliefs, and behavior of parents toward fever and its management. Methods: A cross-sectional study using an online questionnaire was applied over a period of 3 months, from January to March 2018, to parents who were living in Saudi Arabia. The inclusion criteria were a parent who is a resident of Saudi Arabia, with at least one child aged 6 years or less, while incomplete questionnaires, having a child aged more than 6 years, or parents who were not living in Saudi Arabia were excluded. Results: A total of 656 parents completed the questionnaire. More than two-thirds of the subjects were female, the majority of whom were aged between 25–33 years old. The best-reported place to measure the temperature of children was the armpit (46%), followed by the ear (28%) and the mouth (10.7%). More than half of the parents considered their children feverish at a temperature of 38 °C. The majority of parents (79.7%) reported that the most serious side effects of fever were seizure, brain damage (39.3%), coma (29.9%), dehydration (29.7%), and death (25%). The most common method used to measure a child’s temperature was an electronic thermometer (62.3%). The most common antipyretic was paracetamol (84.5%). Conclusions: Our study demonstrates the good knowledge of parents in identifying a feverish temperature using the recommended route and tools for measuring body temperature.

scholarly journals Practice parameter: Temporal lobe and localized neocortical resections for epilepsy

Neurology ◽  
2003 ◽  
Vol 60 (4) ◽  
pp. 538-547 ◽  
Author(s):  
J. Engel ◽  
S. Wiebe ◽  
J. French ◽  
M. Sperling ◽  
P. Williamson ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Controlled Trial ◽  
Mesial Temporal Lobe Epilepsy ◽  
Class I ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Single Class ◽  
Intention To Treat ◽  
Epileptic Syndromes ◽  
Class Iv

Objectives/Methods: To examine evidence for effectiveness of anteromesial temporal lobe and localized neocortical resections for disabling complex partial seizures by systematic review and analysis of the literature since 1990.Results: One intention-to-treat Class I randomized, controlled trial of surgery for mesial temporal lobe epilepsy found that 58% of patients randomized to be evaluated for surgical therapy (64% of those who received surgery) were free of disabling seizures and 10 to 15% were unimproved at the end of 1 year, compared with 8% free of disabling seizures in the group randomized to continued medical therapy. There was a significant improvement in quantitative quality-of-life scores and a trend toward better social function at the end of 1 year for patients in the surgical group, no surgical mortality, and infrequent morbidity. Twenty-four Class IV series of temporal lobe resections yielded essentially identical results. There are similar Class IV results for localized neocortical resections; no Class I or II studies are available.Conclusions: A single Class I study and 24 Class IV studies indicate that the benefits of anteromesial temporal lobe resection for disabling complex partial seizures is greater than continued treatment with antiepileptic drugs, and the risks are at least comparable. For patients who are compromised by such seizures, referral to an epilepsy surgery center should be strongly considered. Further studies are needed to determine if neocortical seizures benefit from surgery, and whether early surgical intervention should be the treatment of choice for certain surgically remediable epileptic syndromes.

scholarly journals Etiology of epilepsy a prospective study of 210 cases

1991 ◽  
Vol 49 (3) ◽  
pp. 251-254 ◽  
Author(s):  
Walter Oleschko Arruda
Keyword(s):  
Ct Scan ◽  
Neurological Examination ◽  
Epileptic Seizures ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Blood Tests ◽  
Generalized Seizures ◽  
A Prospective Study ◽  
Csf Examination

The objective of this study was to establish the etiology of epilepsy in 210 chronic epileptics (110 female, 100 male), aged 14-82 years (34.2±13.3). Patients less than 10 years-old and alcoholism were excluded. All underwent neurological examination, routine blood tests, EEG and CT-scan. Twenty patients (10.5%) were submitted to spinal tap for CSF examination. Neurological examination was abnormal in 26 (12.4%), the EEG in 68 (45.5%), and CT-scan in 93 (44.3%). According to the International Classification of Epileptic Seizures (1981), 101 (48.1%) have generalized seizures, 66 (31.4%) partial seizures secondarily generalized, 25 (11.8%) simple partial and complex partial seizures, and 14 (6.6%) generalized and partial seizures. Four patients (2.0%) could not be classified. In 125 (59.5%) patients the etiology was unknown. Neurocysticercosis accounted for 57 (27.1%) of cases, followed by cerebrovascular disease 8 (3.8%), perinatal damage 5 (2.4%), familial epilepsy 4 (1.9%), head injury 4 (1.9%), infective 1 (0.5%), and miscelanea 6 (2.8%).

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