scholarly journals Single voxel autocorrelation uncovers gradients of temporal dynamics in the hippocampus and entorhinal cortex during rest and navigation

2021 ◽  
Author(s):  
Nichole R Bouffard ◽  
Ali R Golestani ◽  
Iva K Brunec ◽  
Buddhika Bellana ◽  
Morgan D Barense ◽  
...  
Keyword(s):  
Entorhinal Cortex ◽  
Temporal Dynamics ◽  
Multiple Scales ◽  
Future Research ◽  
Signal Stability ◽  
Single Voxel ◽  
Neural Underpinnings ◽  
Fmri Analysis ◽  
First Time ◽  
Goal Directed Behavior

During navigation, information at multiple scales needs to be integrated. Single-unit recordings in rodents suggest that gradients of temporal dynamics in the hippocampus and entorhinal cortex support this integration. In humans, gradients of representation are observed, such that granularity of information represented increases along the long axis of the hippocampus. The neural underpinnings of this gradient in humans, however, are still unknown. Current research is limited by coarse fMRI analysis techniques that obscure the activity of individual voxels, preventing investigation of how moment-to-moment changes in brain signal are organized and how they are related to behavior. Here, we measured the signal stability of single voxels over time to uncover previously unappreciated gradients of temporal dynamics in the hippocampus and entorhinal cortex. Using our novel, single voxel autocorrelation technique, we show for the first time a medial-lateral hippocampal gradient, as well as a continuous autocorrelation gradient along the anterolateral-posteromedial entorhinal extent. Importantly, we show that anterior-posterior and medial-lateral hippocampal autocorrelation gradients were modulated by navigational difficulty, indicating that changes in signal stability are relevant for behavior. Our method and findings open the door for future research on how temporal gradients within these structures support the integration of information for goal-directed behavior.

A Bibliometric Review on Outcome-Based Learning for Graduate Employability: Mapping the Research Front

2021 ◽  
pp. 002205742110164
Author(s):  
Mohammad Zahir Raihan ◽  
Md. Abul Kalam Azad
Keyword(s):  
Research Trend ◽  
Future Research ◽  
Research Front ◽  
Important Research ◽  
R Software ◽  
Future Research Agenda ◽  
Graduate Employability ◽  
Important Research Topic ◽  
Bibliometric Review ◽  
First Time

The outcome-based learning for graduate employability in higher education has been an important research topic among the policymakers, academicians, and researchers over the years. Yet, no bibliometric review on this topic has been published. This study, for the first time, examines bibliometric analysis on this topic examining current research trend and future research agenda. The bibliometrix package in R software and VOSviewer software are used for visualization and interpretation of results. A content analysis is performed to manually examine the bibliometric results.

scholarly journals Exploring Secondary Metabolite Profiles of Stachybotrys spp. by LC-MS/MS

Toxins ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 133 ◽  
Author(s):  
Annika Jagels ◽  
Viktoria Lindemann ◽  
Sebastian Ulrich ◽  
Christoph Gottschalk ◽  
Benedikt Cramer ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Future Research ◽  
Structural Modifications ◽  
Metabolite Profiles ◽  
The Individual ◽  
First Time ◽  
Analytical Standards ◽  
Respective Species

The genus Stachybotrys produces a broad diversity of secondary metabolites, including macrocyclic trichothecenes, atranones, and phenylspirodrimanes. Although the class of the phenylspirodrimanes is the major one and consists of a multitude of metabolites bearing various structural modifications, few investigations have been carried out. Thus, the presented study deals with the quantitative determination of several secondary metabolites produced by distinct Stachybotrys species for comparison of their metabolite profiles. For that purpose, 15 of the primarily produced secondary metabolites were isolated from fungal cultures and structurally characterized in order to be used as analytical standards for the development of an LC-MS/MS multimethod. The developed method was applied to the analysis of micro-scale extracts from 5 different Stachybotrys strains, which were cultured on different media. In that process, spontaneous dialdehyde/lactone isomerization was observed for some of the isolated secondary metabolites, and novel stachybotrychromenes were quantitatively investigated for the first time. The metabolite profiles of Stachybotrys species are considerably influenced by time of growth and substrate availability, as well as the individual biosynthetic potential of the respective species. Regarding the reported adverse effects associated with Stachybotrys growth in building environments, combinatory effects of the investigated secondary metabolites should be addressed and the role of the phenylspirodrimanes re-evaluated in future research.

scholarly journals Forest Quality Dynamic Change and Its Driving Factors Accompanied by Forest Transition in China

Forests ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 733
Author(s):  
Li Gu ◽  
Zhiwen Gong ◽  
Yuankun Bu
Keyword(s):  
Fixed Effects ◽  
Temporal Dynamics ◽  
Spatial Clustering ◽  
Dynamic Change ◽  
Forest Area ◽  
Future Research ◽  
Suitable Model ◽  
Forest Transition ◽  
Significance Level ◽  
Province Level

As ecological and environmental issues have received continuous attention, forest transition has gradually become the frontier and a hot issue, which have implications for biodiversity and ecosystem functioning. In this study, the spatial-temporal dynamics and the spatial determinants of forest quality were investigated using spatial econometric regression models at the province level, which contained 31 provinces, autonomous regions, and municipalities in China. The results showed that forest area, forest volume, forest coverage, and forest quality have greatly increased as of 2018, but uneven forest distribution is an important feature of forest adaptation to the environment. The global Moran’s I value was greater than 0.3, and forest quality of the province level had a positive spatial correlation and exhibited obvious spatial clustering characteristics. In particular, the spatial expansion of forest quality had shown an accelerated concentration. The most suitable model for empirical analysis and interpretation was the Spatial Durbin Model (SDM) with fixed effects. The average annual precipitation and the area ratio of the collective forest were positively correlated with forested quality (significance level 1%). Ultimately, this framework could guide future research, describe actual and potential changes in forest quality associated with forest transitions, and promote management plans that incorporate forest area changes.

scholarly journals Deservingness for "Family 500 +" Benefit in Poland: Qualitative Study of Internet Debates

2021 ◽  
Author(s):  
Piotr Michoń
Keyword(s):  
Future Research ◽  
Online Forums ◽  
Time Data ◽  
Social Surveys ◽  
Cash Benefit ◽  
Internet Forums ◽  
Welfare Attitudes ◽  
New Criterion ◽  
First Time ◽  
The Relationship

AbstractThe need for qualitative research of deservingness perception is strongly emphasised in the literature. This article studies the perception of deservingness for a "Family 500 +"—cash benefit in Poland. For the first time, data from online forums was used in the studies of deservingness and welfare attitudes. It allowed to avoid numerous limitations associated with social surveys. The qualitative analysis showed how participants of Internet debates perceive the criteria of deservingness: control, attitude, reciprocity, identity, need, and what are the relations between the criteria. The impurity of all deservingness criteria was indicated and a new criterion “adequacy” was proposed. Moreover due to the fact that the study concerned a concrete, non-abstract family cash benefit addressed the relationship between the perceived deservingness of children and their parents was pointed out. The vast majority of posts on Internet forums referred to deservingness of parents, not children. This is particularly evident in relation to the criteria of control and reciprocity. Presenting the hypothesis of jealousy and scapegoat strategy, the article also shows the direction of future research on deservingness.

Migrants in Medieval England, c. 500-c. 1500

2020 ◽  
Keyword(s):  
Art History ◽  
Historical Linguistics ◽  
Source Material ◽  
Modern World ◽  
Future Research ◽  
Medieval England ◽  
Medieval Studies ◽  
Wide Range ◽  
Different Types ◽  
First Time

This book is a ground-breaking study of the phenomenon of migration in and to England over the medieval millennium, between c. AD 500 and c. AD 1500. It reaches across traditional scholarly divides, both disciplinary and chronological, to investigate, for the first time, the different types of data and scholarly methods that reveal evidence of migration and mobility within the medieval kingdom of England. England offers the opportunity for studying migration and migrants over the longue durée, because it has been a recognisable political unit for over a millennium and because a wealth of source material has survived from these centuries. The data vary unevenly in quality and quantity across this period, but become considerably more powerful through multi-disciplinary approaches to data collection and interpretation. Fifteen subject specialists synthesise and extend recent research in a wide range of disciplines, including archaeology, art history, genetics, historical linguistics, history, literature and onomastics. They evaluate the capacity of different genres of evidence for addressing questions around migration and its effects on the identities of groups and individuals within medieval England, as well as methodological parameters and future research potential. The book therefore marks an important contribution to medieval studies, and to modern debates on migration and the free movement of people, arguing that migration in the modern world, and its reverberations, cannot be completely understood without taking a broad historical perspective on the topic.

Temporal Dynamics of PERMA Building Blocks and Well-being in Daily Life: An Ecological Momentary Assessment

2021 ◽  
Author(s):  
Saeideh Heshmati ◽  
Zita Oravecz
Keyword(s):  
Ecological Momentary Assessment ◽  
Temporal Dynamics ◽  
Daily Life ◽  
Well Being ◽  
Building Blocks ◽  
Individual Variability ◽  
Future Research ◽  
Dynamical Features ◽  
Ecological Momentary ◽  
Momentary Assessment

Most assessments of well-being have relied on retrospective accounts, measured by global evaluative well-being scales. Following the recent debates focused on the assessment of hedonic and eudaimonic well-being based on the elements of the PERMA theory, the current study aimed to shed further light onto the measurement of PERMA elements in daily life and their temporal dynamics. Through an Ecological Momentary Assessment (EMA) design (N=160), we examined the dynamics of change (e.g., baselines and intra-individual variability) in the PERMA elements using the mPERMA measure, which is an EMA-adapted version of the PERMA Profiler. Findings revealed that momentary experiences of well-being, quantified via PERMA elements, map onto their corresponding hedonic or eudaimonic well-being components, and its dynamical features provide novel insights into predicting global well-being. This work offers avenues for future research to assess well-being in real-time and real-world contexts in ecologically valid ways, while eliminating recall bias.

Opportunities for improving how and when Canadians are informed about new prescription medications

2020 ◽  
pp. 427-447
Keyword(s):  
Lived Experiences ◽  
Mobile Application ◽  
Future Research ◽  
Prescription Medications ◽  
Structured Interviews ◽  
Risks And Benefits ◽  
Medication Information ◽  
First Time ◽  
To Receive ◽  
Larger Sample

The Canadian prescription process requires a person to go through several steps. Prescription medications have associated risks and benefits and it is important for people to be aware of these before and while they are taking medications. One of the approaches to informing people about new prescription medications is that they are provided Consumer Medication Information (CMI). CMI is given to Canadians at the pharmacy when they pick up prescriptions, they will be taking for the first time. This study used semi-structured interviews to examine the lived experiences of a sample of Canadians (N = 36) to identify opportunities for improvement in how and when they are informed about new prescription medications. The findings were synthesized into a journey map. Generally, participants wanted to receive CMI digitally and earlier in the prescription process. Adopting these changes could have several benefits which include loss prevention and increased accessibility to CMI as well as more participatory decision making and opportunities to ask questions. Future research is warranted to explore similar topics with a larger sample and determine what method (e.g., email, website, mobile application) would be most suitable.

scholarly journals Drivers’ Perceptions of Functionality Implied by Terms Used to Describe Automation in Vehicles

2018 ◽  
Vol 62 (1) ◽  
pp. 1893-1897 ◽  
Author(s):  
Michael A. Nees
Keyword(s):  
Future Research ◽  
Automated Vehicle ◽  
Human Driver ◽  
Trust In Automation ◽  
Vehicle Automation ◽  
First Time

The expectations induced by the labels used to describe vehicle automation are important to understand, because research has shown that expectations can affect trust in automation even before a person uses the system for the first time. An online sample of drivers rated the perceived division of driving responsibilities implied by common terms used to describe automation. Ratings of 13 terms were made on a scale from 1 (“human driver is entirely responsible”) to 7 (“vehicle is entirely responsible”) for three driving tasks (steering, accelerating/braking, and monitoring). In several instances, the functionality implied by automation terms did not match the technical definitions of the terms and/or the actual capabilities of the automated vehicle functions currently described by the terms. These exploratory findings may spur and guide future research on this under-examined topic.

scholarly journals Unpacking Associations between Mood Symptoms and Screen Time in Preadolescents: A Network Analysis

2020 ◽  
Author(s):  
Sin-Ying Lin ◽  
Nicholas R Eaton ◽  
Jessica L. Schleider
Keyword(s):  
Graphical Models ◽  
Behavioral Inhibition ◽  
Screen Time ◽  
Parental Monitoring ◽  
Future Research ◽  
Mood Symptoms ◽  
Symptom Profiles ◽  
Different Types ◽  
Symptom Level ◽  
First Time

Mounting evidence highlights the link between screen time and adolescent mood problems. However, there are several shortcomings to the extant literature: (1) this link is relatively underexplored in preadolescents, (2) most existing studies look at mood problems using categorical diagnoses rather than from a symptom-level perspective, despite the heterogeneity within mood disorders, (3) few studies have simultaneously examined the links of mood symptoms with different types of screen time, and (4) family/child-level factors that have shown links to youth psychopathology are not typically considered. This study, for the first time, examined the relationships of mood symptoms with different types of screen time, while accounting for theoretically important factors—parental monitoring and the behavioral inhibition/activation systems (BIS/BAS)—in preadolescents aged 9 to 10 from 9,986 families participating in the Adolescent Brain and Cognitive Development Study. Using mixed graphical models, we found that screen time involving age-inappropriate content was stably and significantly associated with various elevated mood symptoms, independent from other types of screen time, BIS/BAS, and parental monitoring. Additionally, age-inappropriate screen time was associated with increased overall symptom connectivity. Further, preadolescents engaged in high levels of age-inappropriate screen time reported different symptom profiles (i.e., differences in symptom centralities) from common pediatric mood problems. Our findings underline the multifaceted role (i.e., direct associations with symptoms, a moderator for symptom relationships, associations with distinct symptom profiles) of age-inappropriate screen time in preadolescent mood problems. These findings serve as foundations for future research that may facilitate early detection of preadolescents at risk of mood problems.

scholarly journals A Q Methodology Study of Supervisee Roles Within a Counseling Practicum Course

2021 ◽  
Vol 11 (1) ◽  
pp. 1-15
Author(s):  
Eric R. Baltrinic ◽  
Ryan M. Cook ◽  
Heather J. Fye
Keyword(s):  
Clinical Supervision ◽  
Q Methodology ◽  
Counseling Students ◽  
Future Research ◽  
First Semester ◽  
Practicum Students ◽  
Components Analysis ◽  
Counseling Practicum ◽  
First Time ◽  
Q Sort

Counseling students often experience clinical supervision for the first time during their participation in practicum courses. Counseling practicum supervisees new to supervision rely on their supervisors to provide direction and structure in supervision experiences to help them grow professionally and personally. Yet little is known about how students view their roles as new supervisees. Supervisors can benefit from structuring and delivering their courses informed by new supervisees’ perspectives on their roles. Accordingly, the authors conducted a Q methodology study with a purposeful sample of seven counseling practicum students, a doctoral co-instructor, and a counseling practicum instructor engaged in a first-semester counseling practicum course. Principal components analysis with varimax rotation of Q-sort data revealed three factors depicting supervisee roles (i.e., Dutiful, Discerning, and Expressive Learners). Implications for applying findings to improve supervision instruction and student learning are discussed, including limitations and future research suggestions.

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