scholarly journals Generative modeling of histology tissue reduces human annotation effort for segmentation model development.

2021 ◽  
Author(s):  
Brendon R Lutnick ◽  
Pinaki Sarder
Keyword(s):  
Neural Networks ◽  
Renal Biopsy ◽  
Supervised Learning ◽  
Transfer Learning ◽  
Model Development ◽  
Training Data ◽  
Tissue Analysis ◽  
Human In The Loop ◽  
Generative Modeling ◽  
Whole Slide Images

Segmentation of histology tissue whole side images is an important step for tissue analysis. Given enough annotated training data modern neural networks are capable accurate reproducible segmentation, however, the annotation of training datasets is time consuming. Techniques such as human in the loop annotation attempt to reduce this annotation burden, but still require a large amount of initial annotation. Semi-supervised learning, a technique which leverages both labeled and unlabeled data to learn features has shown promise for easing the burden of annotation. Towards this goal, we employ a recently published semi-supervised method: datasetGAN for the segmentation of glomeruli from renal biopsy images. We compare the performance of models trained using datasetGAN and traditional annotation and show that datasetGAN significantly reduces the amount of annotation required to develop a highly performing segmentation model. We also explore the usefulness of using datasetGAN for transfer learning and find that this greatly enhances the performance when a limited number of whole slide images are used for training.

scholarly journals Improving Semi-Supervised Learning for Audio Classification with FixMatch

Electronics ◽  
2021 ◽  
Vol 10 (15) ◽  
pp. 1807
Author(s):  
Sascha Grollmisch ◽  
Estefanía Cano
Keyword(s):  
Neural Networks ◽  
Supervised Learning ◽  
Transfer Learning ◽  
Data Transfer ◽  
State Of The Art ◽  
Training Data ◽  
Audio Classification ◽  
Image Domain ◽  
Full Dataset ◽  
Audio Data

Including unlabeled data in the training process of neural networks using Semi-Supervised Learning (SSL) has shown impressive results in the image domain, where state-of-the-art results were obtained with only a fraction of the labeled data. The commonality between recent SSL methods is that they strongly rely on the augmentation of unannotated data. This is vastly unexplored for audio data. In this work, SSL using the state-of-the-art FixMatch approach is evaluated on three audio classification tasks, including music, industrial sounds, and acoustic scenes. The performance of FixMatch is compared to Convolutional Neural Networks (CNN) trained from scratch, Transfer Learning, and SSL using the Mean Teacher approach. Additionally, a simple yet effective approach for selecting suitable augmentation methods for FixMatch is introduced. FixMatch with the proposed modifications always outperformed Mean Teacher and the CNNs trained from scratch. For the industrial sounds and music datasets, the CNN baseline performance using the full dataset was reached with less than 5% of the initial training data, demonstrating the potential of recent SSL methods for audio data. Transfer Learning outperformed FixMatch only for the most challenging dataset from acoustic scene classification, showing that there is still room for improvement.

scholarly journals Laplacian networks: bounding indicator function smoothness for neural networks robustness

2021 ◽  
Vol 10 ◽  
Author(s):  
Carlos Lassance ◽  
Vincent Gripon ◽  
Antonio Ortega
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Supervised Learning ◽  
Indicator Function ◽  
Training Data ◽  
Theoretical Justification ◽  
The Past ◽  
Noisy Examples

For the past few years, deep learning (DL) robustness (i.e. the ability to maintain the same decision when inputs are subject to perturbations) has become a question of paramount importance, in particular in settings where misclassification can have dramatic consequences. To address this question, authors have proposed different approaches, such as adding regularizers or training using noisy examples. In this paper we introduce a regularizer based on the Laplacian of similarity graphs obtained from the representation of training data at each layer of the DL architecture. This regularizer penalizes large changes (across consecutive layers in the architecture) in the distance between examples of different classes, and as such enforces smooth variations of the class boundaries. We provide theoretical justification for this regularizer and demonstrate its effectiveness to improve robustness on classical supervised learning vision datasets for various types of perturbations. We also show it can be combined with existing methods to increase overall robustness.

scholarly journals Transfer Learning with Deep Recurrent Neural Networks for Remaining Useful Life Estimation

2018 ◽  
Vol 8 (12) ◽  
pp. 2416 ◽  
Author(s):  
Ansi Zhang ◽  
Honglei Wang ◽  
Shaobo Li ◽  
Yuxin Cui ◽  
Zhonghao Liu ◽  
...  
Keyword(s):  
Neural Networks ◽  
Transfer Learning ◽  
Recurrent Neural Networks ◽  
Prediction Models ◽  
Learning Algorithm ◽  
Remaining Useful Life ◽  
Operating Conditions ◽  
Training Data ◽  
Good Prediction ◽  
Useful Life

Prognostics, such as remaining useful life (RUL) prediction, is a crucial task in condition-based maintenance. A major challenge in data-driven prognostics is the difficulty of obtaining a sufficient number of samples of failure progression. However, for traditional machine learning methods and deep neural networks, enough training data is a prerequisite to train good prediction models. In this work, we proposed a transfer learning algorithm based on Bi-directional Long Short-Term Memory (BLSTM) recurrent neural networks for RUL estimation, in which the models can be first trained on different but related datasets and then fine-tuned by the target dataset. Extensive experimental results show that transfer learning can in general improve the prediction models on the dataset with a small number of samples. There is one exception that when transferring from multi-type operating conditions to single operating conditions, transfer learning led to a worse result.

scholarly journals Dealing with Lack of Training Data for Convolutional Neural Networks: The Case of Digital Pathology

Electronics ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 256
Author(s):  
Francesco Ponzio ◽  
Gianvito Urgese ◽  
Elisa Ficarra ◽  
Santa Di Cataldo
Keyword(s):  
Neural Networks ◽  
Transfer Learning ◽  
Convolutional Neural Networks ◽  
Digital Pathology ◽  
Training Data ◽  
Automated Classification ◽  
Computationally Efficient ◽  
Deep Convolutional Neural Networks ◽  
Cad Systems ◽  
Tissue Characteristics

Thanks to their capability to learn generalizable descriptors directly from images, deep Convolutional Neural Networks (CNNs) seem the ideal solution to most pattern recognition problems. On the other hand, to learn the image representation, CNNs need huge sets of annotated samples that are unfeasible in many every-day scenarios. This is the case, for example, of Computer-Aided Diagnosis (CAD) systems for digital pathology, where additional challenges are posed by the high variability of the cancerous tissue characteristics. In our experiments, state-of-the-art CNNs trained from scratch on histological images were less accurate and less robust to variability than a traditional machine learning framework, highlighting all the issues of fully training deep networks with limited data from real patients. To solve this problem, we designed and compared three transfer learning frameworks, leveraging CNNs pre-trained on non-medical images. This approach obtained very high accuracy, requiring much less computational resource for the training. Our findings demonstrate that transfer learning is a solution to the automated classification of histological samples and solves the problem of designing accurate and computationally-efficient CAD systems with limited training data.

scholarly journals Enhancing Image Diagnosis by the Implementation of Transfer Classifiers

2019 ◽  
Vol 8 (3) ◽  
pp. 999-1002
Keyword(s):  
Supervised Learning ◽  
Transfer Learning ◽  
Training Data ◽  
Data Sets ◽  
Learning Approaches ◽  
Learning Techniques ◽  
Image Diagnosis ◽  
Sensitivity Problem ◽  
Common Application ◽  
Target Data

Images generated from a variety of sources and foundations today can pose difficulty for a user to interpret similarity in them or analyze them for further use because of their segmentation policies. This unconventionality can generate many errors, because of which the previously used traditional methodologies such as supervised learning techniques less resourceful, which requires huge quantity of labelled training data which mirrors the desired target data. This paper thus puts forward the mechanism of an alternative technique i.e. transfer learning to be used in image diagnosis so that efficiency and accuracy among images can be achieved. This type of mechanism deals with variation in the desired and actual data used for training and the outlier sensitivity, which ultimately enhances the predictions by giving better results in various areas, thus leaving the traditional methodologies behind. The following analysis further discusses about three types of transfer classifiers which can be applied using only small volume of training data sets and their contrast with the traditional method which requires huge quantities of training data having attributes with slight changes. The three different separators were compared amongst them and also together from the traditional methodology being used for a very common application used in our daily life. Also, commonly occurring problems such as the outlier sensitivity problem were taken into consideration and measures were taken to recognise and improvise them. On further research it was observed that the performance of transfer learning exceeds that of the conventional supervised learning approaches being used for small amount of characteristic training data provided reducing the stratification errors to a great extent

scholarly journals Transfer Learning for Inference of Metastatic Origin from Whole Slide Histology

2021 ◽  
Author(s):  
Geoffrey F. Schau ◽  
Hassan Ghani ◽  
Erik A. Burlingame ◽  
Guillaume Thibault ◽  
Joe W. Gray ◽  
...  
Keyword(s):  
Deep Learning ◽  
Transfer Learning ◽  
Primary Tumor ◽  
Large Scale ◽  
Metastatic Cancer ◽  
Clinical Diagnostics ◽  
Training Data ◽  
Fine Tuning ◽  
Learning Approach ◽  
Whole Slide Images

AbstractAccurate diagnosis of metastatic cancer is essential for prescribing optimal control strategies to halt further spread of metastasizing disease. While pathological inspection aided by immunohistochemistry staining provides a valuable gold standard for clinical diagnostics, deep learning methods have emerged as powerful tools for identifying clinically relevant features of whole slide histology relevant to a tumor’s metastatic origin. Although deep learning models require significant training data to learn effectively, transfer learning paradigms provide mechanisms to circumvent limited training data by first training a model on related data prior to fine-tuning on smaller data sets of interest. In this work we propose a transfer learning approach that trains a convolutional neural network to infer the metastatic origin of tumor tissue from whole slide images of hematoxylin and eosin (H&E) stained tissue sections and illustrate the advantages of pre-training network on whole slide images of primary tumor morphology. We further characterize statistical dissimilarity between primary and metastatic tumors of various indications on patch-level images to highlight limitations of our indication-specific transfer learning approach. Using a primary-to-metastatic transfer learning approach, we achieved mean class-specific areas under receiver operator characteristics curve (AUROC) of 0.779, which outperformed comparable models trained on only images of primary tumor (mean AUROC of 0.691) or trained on only images of metastatic tumor (mean AUROC of 0.675), supporting the use of large scale primary tumor imaging data in developing computer vision models to characterize metastatic origin of tumor lesions.

scholarly journals Plastic Gasket Defect Detection Based on Transfer Learning

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Xieyi Chen ◽  
Dongyun Wang ◽  
Jinjun Shao ◽  
Jun Fan
Keyword(s):  
Neural Network ◽  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
Transfer Learning ◽  
Defect Detection ◽  
Data Augmentation ◽  
Surface Defects ◽  
Visual Detection ◽  
Training Data

To automatically detect plastic gasket defects, a set of plastic gasket defect visual detection devices based on GoogLeNet Inception-V2 transfer learning was designed and established in this study. The GoogLeNet Inception-V2 deep convolutional neural network (DCNN) was adopted to extract and classify the defect features of plastic gaskets to solve the problem of their numerous surface defects and difficulty in extracting and classifying the features. Deep learning applications require a large amount of training data to avoid model overfitting, but there are few datasets of plastic gasket defects. To address this issue, data augmentation was applied to our dataset. Finally, the performance of the three convolutional neural networks was comprehensively compared. The results showed that the GoogLeNet Inception-V2 transfer learning model had a better performance in less time. It means it had higher accuracy, reliability, and efficiency on the dataset used in this paper.

scholarly journals Domain Adaptation and Transfer Learning in StochasticNets

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
Mohammad Javad Shafiee ◽  
Parthipan Siva ◽  
Paul Fieguth ◽  
Alexander Wong
Keyword(s):  
Machine Learning ◽  
Neural Networks ◽  
Transfer Learning ◽  
Deep Neural Networks ◽  
Domain Adaptation ◽  
Experimental Results ◽  
Training Data ◽  
Learning Research ◽  
Sparse Connectivity

<p>Transfer learning is a recent field of machine learning research that<br />aims to resolve the challenge of dealing with insufficient training<br />data in the domain of interest. This is a particular issue with traditional<br />deep neural networks where a large amount of training<br />data is needed. Recently, StochasticNets was proposed to take<br />advantage of sparse connectivity in order to decrease the number<br />of parameters that needs to be learned, which in turn may relax<br />training data size requirements. In this paper, we study the efficacy<br />of transfer learning on StochasticNet frameworks. Experimental results<br />show 7% improvement on StochasticNet performance when<br />the transfer learning is applied in training step.</p>

scholarly journals Transfer Learning with Graph Neural Networks for Optoelectronic Properties of Conjugated Oligomers

2020 ◽  
Author(s):  
Chee Kong Lee ◽  
Chengqiang Lu ◽  
Yue Yu ◽  
Qiming Sun ◽  
Chang-Yu Hsieh ◽  
...  
Keyword(s):  
Neural Networks ◽  
Excited State ◽  
Transfer Learning ◽  
State Energy ◽  
Optoelectronic Properties ◽  
Training Data ◽  
Conjugated Oligomers ◽  
Excited State Energy ◽  
Tddft Calculations ◽  
Graph Neural Networks

Despite the remarkable progress of machine learning (ML) techniques in chemistry, modeling the optoelectronic properties of long conjugated oligomers and polymers with ML remains challenging due to the difficulty in obtaining sufficient training data. Here we use transfer learning to address the data scarcity issue by pre-training graph neural networks using data from short oligomers. With only a few hundred training data, we are able to achieve an average error of about 0.1 eV for excited state energy of oligothiophenes against TDDFT calculations. We show that the success of our transfer learning approach relies on the relative locality of low-lying electronic excitations in long conjugated oligomers. Finally, we demonstrate the transferability of our approach by modeling the lowest-lying excited-state energies of poly(3-hexylthiopnene) (P3HT) in its single-crystal and solution phases using the transfer learning models trained with data of gas-phase oligothiophenes. The transfer learning predicted excited-state energy distributions agree quantitatively with TDDFT calculations and capture some important qualitative features observed in experimental absorption spectra.<br>

scholarly journals A Payload Based Malicious HTTP Traffic Detection Method Using Transfer Semi-Supervised Learning

2021 ◽  
Vol 11 (16) ◽  
pp. 7188
Author(s):  
Tieming Chen ◽  
Yunpeng Chen ◽  
Mingqi Lv ◽  
Gongxun He ◽  
Tiantian Zhu ◽  
...  
Keyword(s):  
Deep Learning ◽  
Supervised Learning ◽  
Transfer Learning ◽  
Web Application ◽  
Data Augmentation ◽  
Learning Algorithm ◽  
Training Data ◽  
Small Data ◽  
Detection Model ◽  
Traffic Detection

Malicious HTTP traffic detection plays an important role in web application security. Most existing work applies machine learning and deep learning techniques to build the malicious HTTP traffic detection model. However, they still suffer from the problems of huge training data collection cost and low cross-dataset generalization ability. Aiming at these problems, this paper proposes DeepPTSD, a deep learning method for payload based malicious HTTP traffic detection. First, it treats the malicious HTTP traffic detection as a text classification problem and trains the initial detection model using TextCNN on a public dataset, and then adapts the initial detection model to the target dataset based on a transfer learning algorithm. Second, in the transfer learning procedure, it uses a semi-supervised learning algorithm to accomplish the model adaptation task. The semi-supervised learning algorithm enhances the target dataset based on a HTTP payload data augmentation mechanism to exploit both the labeled and unlabeled data. We evaluate DeepPTSD on two real HTTP traffic datasets. The results show that DeepPTSD has competitive performance under the small data condition.

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