scholarly journals Covid-19 social distancing: when less is more

2021 ◽  
Author(s):  
C. Neuwirth ◽  
C. Gruber
Keyword(s):  
Intensive Care ◽  
Seasonal Variation ◽  
Negative Relationship ◽  
Opportunity To Learn ◽  
Tipping Points ◽  
Social Contacts ◽  
Low Transmission ◽  
Social Distancing ◽  
Less Is More

AbstractCovid-19 is the first digitally documented pandemic in history, presenting a unique opportunity to learn how to best deal with similar crises in the future. In this study we have carried out a model-based evaluation of the effectiveness of social distancing, using Austria and Slovenia as examples. Whereas the majority of comparable studies have postulated a negative relationship between the stringency of social distancing (reduction in social contacts) and the scale of the epidemic, our model has suggested a sinusoidal relationship, with tipping points at which the system changes its predominant regime from ‘less social distancing – more cumulative deaths and infections’ to ‘less social distancing – fewer cumulative deaths and infections’. This relationship was found to persist in scenarios with distinct seasonal variation in transmission and limited national intensive care capabilities. In such situations, relaxing social distancing during low transmission seasons (spring and summer) was found to relieve pressure from high transmission seasons (fall and winter) thus reducing the total number of infections and fatalities. Strategies that take into account this relationship could be particularly beneficial in situations where long-term containment is not feasible.

scholarly journals The challenges of containing SARS-CoV-2 via test-trace-and-isolate

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Sebastian Contreras ◽  
Jonas Dehning ◽  
Matthias Loidolt ◽  
Johannes Zierenberg ◽  
F. Paul Spitzner ◽  
...  
Keyword(s):  
Analytical Model ◽  
Reproduction Number ◽  
Tipping Points ◽  
Social Distancing ◽  
Promising Tool

AbstractWithout a cure, vaccine, or proven long-term immunity against SARS-CoV-2, test-trace-and-isolate (TTI) strategies present a promising tool to contain its spread. For any TTI strategy, however, mitigation is challenged by pre- and asymptomatic transmission, TTI-avoiders, and undetected spreaders, which strongly contribute to ”hidden" infection chains. Here, we study a semi-analytical model and identify two tipping points between controlled and uncontrolled spread: (1) the behavior-driven reproduction number $${R}_{t}^{H}$$ R t H of the hidden chains becomes too large to be compensated by the TTI capabilities, and (2) the number of new infections exceeds the tracing capacity. Both trigger a self-accelerating spread. We investigate how these tipping points depend on challenges like limited cooperation, missing contacts, and imperfect isolation. Our results suggest that TTI alone is insufficient to contain an otherwise unhindered spread of SARS-CoV-2, implying that complementary measures like social distancing and improved hygiene remain necessary.

Survival after cardiac surgery and long-term intensive care unit stay

2013 ◽  
Vol 61 (S 01) ◽  
Author(s):  
C Schimmer ◽  
K Hamouda ◽  
M Özkur ◽  
SP Sommer ◽  
I Aleksic ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Cardiac Surgery ◽  
Intensive Care ◽  
Intensive Care Unit Stay

Risk Attitude and Corporate Investment under Output Market Uncertainty: Evidence from The Mekong River Delta, Vietnam

2016 ◽  
pp. 59-70
Author(s):  
Ninh Le Khuong ◽  
Nghiem Le Tan ◽  
Tho Huynh Huu
Keyword(s):  
Negative Relationship ◽  
Risk Attitude ◽  
Business Strategies ◽  
Risk Averse ◽  
Market Uncertainty ◽  
Firm Investment ◽  
Output Market ◽  
The Impact ◽  
The Relationship

This paper aims to detect the impact of firm managers’ risk attitude on the relationship between the degree of output market uncertainty and firm investment. The findings show that there is a negative relationship between these two aspects for risk-averse managers while there is a positive relationship for risk-loving ones, since they have different utility functions. Based on the findings, this paper proposes recommendations for firm managers to take into account when making investment decisions and long-term business strategies as well.

Long Term Monitoring of the Macrobenthos of the Upper Clyde Estuary

1984 ◽  
Vol 16 (5-7) ◽  
pp. 359-373 ◽  
Author(s):  
Anne R Henderson
Keyword(s):  
Water Quality ◽  
Seasonal Variation ◽  
Organic Pollution ◽  
Long Term Changes ◽  
Pollution Loading ◽  
Faunal Density ◽  
History Of ◽  
Long Term Monitoring ◽  
Term Monitoring

The sublittoral macrobenthic invertebrate populations of the Upper Clyde Estuary are described. The estuary has a long history of organic pollution. The long term changes in species composition, faunal density and dominance patterns between 1974 and 1980 are presented. The fauna is dominated by brackish, pollution tolerant oligochaetes and polychaetes. Fluctuations in populations can be related to both seasonal variation in environmental conditions and long term improvements in water quality through a reduction in pollution loading to the estuary.

scholarly journals Cystatin C predicts long term mortality better than creatinine in a nationwide study of intensive care patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Johanna Helmersson-Karlqvist ◽  
Miklos Lipcsey ◽  
Johan Ärnlöv ◽  
Max Bell ◽  
Bo Ravn ◽  
...  
Keyword(s):  
Intensive Care ◽  
Critically Ill ◽  
Risk Prediction ◽  
Cystatin C ◽  
Mortality Risk ◽  
Critically Ill Patients ◽  
Cox Regression ◽  
Sample Tube ◽  
Long Term Mortality

AbstractDecreased glomerular filtration rate (GFR) is linked to poor survival. The predictive value of creatinine estimated GFR (eGFR) and cystatin C eGFR in critically ill patients may differ substantially, but has been less studied. This study compares long-term mortality risk prediction by eGFR using a creatinine equation (CKD-EPI), a cystatin C equation (CAPA) and a combined creatinine/cystatin C equation (CKD-EPI), in 22,488 patients treated in intensive care at three University Hospitals in Sweden, between 2004 and 2015. Patients were analysed for both creatinine and cystatin C on the same blood sample tube at admission, using accredited laboratory methods. During follow-up (median 5.1 years) 8401 (37%) patients died. Reduced eGFR was significantly associated with death by all eGFR-equations in Cox regression models. However, patients reclassified to a lower GFR-category by using the cystatin C-based equation, as compared to the creatinine-based equation, had significantly higher mortality risk compared to the referent patients not reclassified. The cystatin C equation increased C-statistics for death prediction (p < 0.001 vs. creatinine, p = 0.013 vs. combined equation). In conclusion, this data favours the sole cystatin C equation rather than the creatinine or combined equations when estimating GFR for risk prediction purposes in critically ill patients.

Sportliche Leistung von Pferden, die als Fohlen intensivmedizinischer Behandlung bedurften

2019 ◽  
Vol 47 (06) ◽  
pp. 399-399
Author(s):  
Lukas Demattio
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Sich Eine ◽  
Factors Associated ◽  
Intensivmedizinische Behandlung ◽  
Sportliche Leistung

Studies AC, Chidlow H, Ere SG et al. Factors associated with long-term athletic outcome in Thoroughbred neonates admitted to an intensive care unit. Equine Vet J 2019; 51: 716–719 Für viele Pferdezüchter stellt sich immer wieder die Frage, wie viel Geld in ein Fohlen investiert werden soll, wenn dieses tierärztlicher Behandlung bedarf. Lohnt sich eine intensivmedizinische Behandlung für ein Fohlen, das für eine sportliche Nutzung vorgesehen ist? Diese Frage versuchten die Autoren in der Studie zu beantworten.

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