In his 1952 paper ‘The chemical basis of morphogenesis’ Turing postulated his now famous Morphogenesis Equation. He claimed that his theory would explain why plants and animals took the shapes they did. When I joined him, Turing suggested that I might solve his equation in three dimensions, a new problem. After many manipulations using rather sophisticated mathematics and one of the first factory-produced computers in the UK, I derived a series of solutions to Turing’s equation. I showed that these solutions explained the shapes of specimens of the marine creatures known as Radiolaria, and that they corresponded very closely to the actual spiny shapes of real radiolarians. My work provided further evidence for Turing’s theory of morphogenesis, and in particular for his belief that the external shapes exhibited by Radiolaria can be explained by his reaction–diffusion mechanism. While working in the Computing Machine Laboratory at the University of Manchester in the early 1950s, Alan Turing reignited the interests he had had in both botany and biology from his early youth. During his school-days he was more interested in the structure of the flowers on the school sports field than in the games played there (see Fig. 1.3). It is known that during the Second World War he discussed the problem of phyllotaxis (the arrangement of leaves and florets in plants), and then at Manchester he had some conversations with Claude Wardlaw, the Professor of Botany in the University. Turing was keen to take forward the work that D’Arcy Thompson had published in On Growth and Form in 1917. In his now-famous paper of 1952 Turing solved his own ‘Equation of Morphogenesis’ in two dimensions, and demonstrated a solution that could explain the ‘dappling’—the black-and-white patterns—on cows. The next step was for me to solve Turing’s equation in three dimensions. The two-dimensional case concerns only surface features of organisms, such as dappling, spots, and stripes, whereas the three-dimensional version concerns the overall shape of an organism. In 1953 I joined Turing as a research student in the University of Manchester, and he set me the task of solving his equation in three dimensions. A remarkable journey of collaboration began. Turing chatted to me in a very friendly fashion.
Self-assembly and plasticity of synaptic domains through a reaction-diffusion mechanism
