Titanium dioxide nanowires-based interdigitated electrodes for biomedical application

Author(s):  
Sharipah Nadzirah Syed Ahmad Ayob ◽  
U. Hashim
2021 ◽  
Vol 285 ◽  
pp. 129100
Author(s):  
Ivana Malagurski ◽  
Ruggero Frison ◽  
Anjani K. Maurya ◽  
Antonia Neels ◽  
Boban Andjelkovic ◽  
...  

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0139766 ◽  
Author(s):  
Sh. Nadzirah ◽  
N. Azizah ◽  
Uda Hashim ◽  
Subash C. B. Gopinath ◽  
Mohd Kashif

2013 ◽  
Vol 832 ◽  
pp. 124-127 ◽  
Author(s):  
Sharipah Nadzirah ◽  
Uda Hashim

This paper studies the Capacitance-Frequency of titanium dioxide (TiO2) thin film-based interdigitated electrodes (IDEs) for ss-DNA immobilization. TiO2thin film was deposited on P-type silicon dioxide (SiO2) (1 0 0) substrates using monoethanolamine (MEA) sol-gel route by spin-coating method. Titanium butoxide was used as a precursor source while ethanol and MEA were used as a disperser and stabilizer respectively. Metal IDEs of aluminium (Al) was deposited on the synthesized films for the electrical characterization. From the electrical data, it proves that the synthesized TiO2thin film is effective and can be used for the synthesis of TiO2thin films with biomedical application.


Titanium dioxide (TiO2 ) is a widely studied material and exists in three major crystal structures: rutile, brookite and anatase. Due to its advantages in high chemical and thermal stability, non-toxicity, high catalytic activity, resistance to corrosion, and high reactivity under ultraviolet light (<387 nm),it can be used in many applications such as photo catalysis, photovoltaics, sensors, hydrogen generators batteries, self-cleaning, electrochromic devices and also used in some biomedical application for site specific drug delivery . These applications in various fields depends not only on the properties of the TiO2 material but also it involves in modifying TiO2 structure and doping of other element on it which will show adverse impact in application of TiO2 with the surrounding environment. In this review, we are discussing about the synthesis, properties, and applications of titanium dioxide nanoparticle (TiO2 NP) in various fields.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Yiying Bian ◽  
Han-Young Chung ◽  
Ok-Nam Bae ◽  
Kyung-Min Lim ◽  
Jin-Ho Chung ◽  
...  

Abstract Background Expanding biomedical application of anatase titanium dioxide (TiO2) nanoparticles (NPs) is raising the public concern on its potential health hazards. Here, we demonstrated that TiO2 NPs can increase phosphatidylserine (PS) exposure and procoagulant activity of red blood cells (RBCs), which may contribute to thrombosis. Results We conducted in vitro studies using RBCs freshly isolated from healthy male volunteers. TiO2 NPs exposure (≦ 25 μg/mL) induced PS exposure and microvesicles (MV) generation accompanied by morphological changes of RBCs. While ROS generation was not observed following the exposure to TiO2 NPs, intracellular calcium increased and caspase-3 was activated, which up-regulated scramblase activity, leading to PS exposure. RBCs exposed to TiO2 NPs could increase procoagulant activity as measured by accelerated thrombin generation, and enhancement of RBC-endothelial cells adhesion and RBC-RBC aggregation. Confirming the procoagulant activation of RBC in vitro, exposure to TiO2 NPs (2 mg/kg intravenously injection) in rats increased thrombus formation in the venous thrombosis model. Conclusion Collectively, these results suggest that anatase TiO2 NPs may harbor prothrombotic risks by promoting the procoagulant activity of RBCs, which needs attention for its biomedical application.


2009 ◽  
Vol 00 (00) ◽  
pp. 090915102728058-8
Author(s):  
Yoshiteru Kato ◽  
Yasuhiko Nakashima ◽  
Naoki Shino ◽  
Koichi Sasaki ◽  
Akihiro Hosokawa ◽  
...  

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