Flexible Ablation Device with Single Applicator Structure that Supports both Radiofrequency and Microwave Energy Delivery

Author(s):  
Patrick Burn ◽  
Pallav Shah ◽  
Christopher P. Hancock
2017 ◽  
Vol 9 (8) ◽  
pp. 1575-1582 ◽  
Author(s):  
Shaun C. Preston ◽  
Malcolm White ◽  
Brian Saunders ◽  
Zacharias Tsiamoulos ◽  
Christoper P. Hancock

A novel transmission line structure has been developed to facilitate the delivery of both adrenaline and microwave energy to achieve hemostasis. A proximal end impedance transformer and radiative tip have been designed and manufactured to provide good match between the novel hollow transmission line and the microwave source and tissue, respectively. Further consideration of the challenges and problems encountered along with evidence of successful microwave energy delivery at 5.8 GHz into porcine liver model providing a controlled and focused coagulation zone of approximately 5 mm.


2017 ◽  
Vol 112 ◽  
pp. 13-17 ◽  
Author(s):  
D. McLean ◽  
L. Meers ◽  
J. Ralph ◽  
J.S. Owen ◽  
A. Small

2017 ◽  
Vol 34 (1) ◽  
pp. 11-18 ◽  
Author(s):  
William Keun Chan Park ◽  
Aaron Wilhelm Palmer Maxwell ◽  
Victoria Elizabeth Frank ◽  
Michael Patrick Primmer ◽  
Jarod Brian Paul ◽  
...  

Author(s):  
Yuji WADA ◽  
Eiichi SUZUKI ◽  
Motoyasu SATO
Keyword(s):  

2020 ◽  
Vol 17 (8) ◽  
pp. 594-609
Author(s):  
Preetismita Borah ◽  
Vhatkar Dattatraya Shivling ◽  
Bimal Krishna Banik ◽  
Biswa Mohan Sahoo

In recent years, hybrid systems are gaining considerable attention owing to their various biological applications in drug development. Generally, hybrid molecules are constructed from different molecular entities to generate a new functional molecule with improved biological activities. There already exist a large number of naturally occurring hybrid molecules based on both non-steroid and steroid frameworks synthesized by nature through mixed biosynthetic pathways such as, a) integration of the different biosynthetic pathways or b) Carbon- Carbon bond formation between different components derived through different biosynthetic pathways. Multicomponent reactions are a great way to generate efficient libraries of hybrid compounds with high diversity. Throughout the scientific history, the most common factors developing technologies are less energy consumption and avoiding the use of hazardous reagents. In this case, microwave energy plays a vital role in chemical transformations since it involves two very essential criteria of synthesis, minimizing energy consumption required for heating and time required for the reaction. This review summarizes the use of microwave energy in the synthesis of steroidal and non-steroidal hybrid molecules and the use of multicomponent reactions.


2020 ◽  
Vol 10 (14) ◽  
pp. 4761
Author(s):  
Milorad Papic ◽  
Svetlana Ekisheva ◽  
Eduardo Cotilla-Sanchez

Modern risk analysis studies of the power system increasingly rely on big datasets, either synthesized, simulated, or real utility data. Particularly in the transmission system, outage events have a strong influence on the reliability, resilience, and security of the overall energy delivery infrastructure. In this paper we analyze historical outage data for transmission system components and discuss the implications of nearby overlapping outages with respect to resilience of the power system. We carry out a risk-based assessment using North American Electric Reliability Corporation (NERC) Transmission Availability Data System (TADS) for the North American bulk power system (BPS). We found that the quantification of nearby unscheduled outage clusters would improve the response times for operators to readjust the system and provide better resilience still under the standard definition of N-1 security. Finally, we propose future steps to investigate the relationship between clusters of outages and their electrical proximity, in order to improve operator actions in the operation horizon.


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