This article analyzes and studies the importance of establishing a real estate information system in the real estate market. The research content of this article includes improving the efficiency of data utilization, formulating the important support of marketing strategy, and the inevitable trend of marketing system reform. The author studies the system technical route analysis, functional module design, logical hierarchical structure design, overall database design, data collection and storage method design, system key technology application, etc. The purpose of this article is to improve the applicability of information systems to regional development and to enhance the use value of big data technology itself.