The impact of CAD in the computational design process on total system development [microwave devices]

Author(s):  
L. Ives ◽  
W.F. Vogler
1986 ◽  
Vol 30 (9) ◽  
pp. 905-907
Author(s):  
Robert M. Elton

The MANPRINT (Manpower and Personnel Integration) Program is a comprehensive program designed to enhance human performance and reliability during weapon system development with the overall goal – of optimizing total system performance. Total system performance is a function of equipment performance and human performance as they are affected under varying environmental conditions which includes physical, social and operational conditions. The challenge the U.S. Army has today is to ensure these issues are addressed early in and continuously throughout the design process.


Author(s):  
Olivier L. de Weck

The main goal of META design is to achieve a factor five (5x) improvement in product development speed for cyber-electro-physical systems compared to current practice. The method claims to achieve this speedup by a combination of three main mechanisms: 1. The deliberate use of layers of abstraction. High-level functional requirements are used to explore architectures immediately rather than waiting for downstream level 2, 3, 4 … requirements to be defined. 2. The development and use of an extensive and trusted component (C2M2L) model library. Rather than designing all components from scratch, the META process allows importing component models directly from a library in order to quickly compose functional designs. 3. The ability to find emergent behaviors and problems ahead of time during virtual Verification and Validation (V&V) and generating designs that are correct-by-construction allows a more streamlined design process and avoids costly design iterations that often lead to expensive design changes. This paper quantifies the impact of these main META mechanisms with a sophisticated System Dynamics (SD) model that allows simulating development projects over time. META compares favorably against a simulation of a traditional design process due to the generation of late engineering changes in a traditional design-build-test-redesign environment. The benchmark case analyzed in this paper contained 3,000 requirements, and the results show a dramatic improvement for project completion schedule with a demonstrated speedup factor of 4.4 (70 months versus about 16 months). In the simulated META process we used 3 layers of abstraction, 50% novelty and a model library integrity of 80% with 70% of problems are caught early. The results were also validated against data from the B777 Electric Power System (EPS) design project at UTC where a speedup factor of 3.8 was demonstrated. The paper contains a useful sensitivity analysis that helps establish requirements and bounds on the META process and tool-chain itself that should enable the desired 5x speedup factor.


2008 ◽  
Vol 1 (4) ◽  
pp. A353
Author(s):  
Shenandoah Robinson ◽  
Qing Li

Introduction Many infants born very preterm who suffer brain damage most likely experienced a combined insult from intrauterine infection and placental insufficiency. Damage is thought to be synergistic rather than additive but the mechanisms of combined injury remain elusive. A combination of lipopolysaccharide-induced inflammation and hypoxia-ischemia has been used in rats to model the dual insult that occurs in human infants prenatally. Erythropoietin, a pleiotrophic cytokine that is essential for central nervous system development, ameliorates brain injury after isolated hypoxic-ischemic or inflammatory insults through different intracellular signaling pathways. We hypothesized that exogenous neonatal EPO administration would lessen the damage of a combined prenatal insult in rats. Methods On embryonic Day 18 fetal rats experienced 60 minutes of transient uterine artery occlusion with or without intracervical LPS administration with sham controls receiving surgery but no occlusion and saline for LPS. Survival was recorded and histological biochemical and functional assays were performed. Means were compared with ANOVA with Tukey HSD post hoc analysis. Results After a combined insult of HI and 0.15-mg/kg LPS on E18 the survival of pups by postnatal Day 1 (P1) decreased from 77% with HI alone to 22% for LPS plus HI. When exogenous systemic EPO was administered P1–P3 survival to P9 improved markedly from 40% (2 of 5) for saline-treated insult pups to 100% (6 of 6) for EPO-treated. Initial histological analyses show EPO decreases the number of brain activated caspase 3 and activated microglia by P9. Additional analyses will be presented. Conclusion As at least 60% of placentas from infants born pre-term show evidence of chorioamnionitis, assessment of the impact of exogenous EPO on a model of a combination injury is essential prior to proceeding with a clinical trial. Initial results indicate neonatal exogenous EPO mitigates damage from the combined insult.


Energies ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 323
Author(s):  
Guilherme Pontes Luz ◽  
Rodrigo Amaro e Silva

The recently approved regulation on Energy Communities in Europe is paving the way for new collective forms of energy consumption and production, mainly based on photovoltaics. However, energy modeling approaches that can adequately evaluate the impact of these new regulations on energy community configurations are still lacking, particularly with regards to the grid tariffs imposed on collective systems. Thus, the present work models three different energy community configurations sustained on collective photovoltaics self-consumption for a small city in southern Portugal. This energy community, which integrates the city consumers and a local winery, was modeled using the Python-based Calliope framework. Using real electricity demand data from power transformers and an actual winery, the techno-economic feasibility of each configuration was assessed. Results show that all collective arrangements can promote a higher penetration of photovoltaic capacity (up to 23%) and a modest reduction in the overall cost of electricity (up to 8%). However, there are clear trade-offs between the different pathways: more centralized configurations have 53% lower installation costs but are more sensitive to grid use costs (which can represent up to 74% of the total system costs). Moreover, key actor’s individual self-consumption rate may decrease by 10% in order to benefit the energy community as a whole.


2021 ◽  
Vol 22 (11) ◽  
pp. 5692
Author(s):  
Mayra Colardo ◽  
Noemi Martella ◽  
Daniele Pensabene ◽  
Silvia Siteni ◽  
Sabrina Di Bartolomeo ◽  
...  

Neurotrophins constitute a family of growth factors initially characterized as predominant mediators of nervous system development, neuronal survival, regeneration and plasticity. Their biological activity is promoted by the binding of two different types of receptors, leading to the generation of multiple and variegated signaling cascades in the target cells. Increasing evidence indicates that neurotrophins are also emerging as crucial regulators of metabolic processes in both neuronal and non-neuronal cells. In this context, it has been reported that neurotrophins affect redox balance, autophagy, glucose homeostasis and energy expenditure. Additionally, the trophic support provided by these secreted factors may involve the regulation of cholesterol metabolism. In this review, we examine the neurotrophins’ signaling pathways and their effects on metabolism by critically discussing the most up-to-date information. In particular, we gather experimental evidence demonstrating the impact of these growth factors on cholesterol metabolism.


Author(s):  
Camila Freitas Salgueiredo ◽  
Armand Hatchuel

AbstractIs biologically inspired design only an analogical transfer from biology to engineering? Actually, nature does not always bring “hands-on” solutions that can be analogically applied in classic engineering. Then, what are the different operations that are involved in the bioinspiration process and what are the conditions allowing this process to produce a bioinspired design? In this paper, we model the whole design process in which bioinspiration is only one element. To build this model, we use a general design theory, concept–knowledge theory, because it allows one to capture analogy as well as all other knowledge changes that lead to the design of a bioinspired solution. We ground this model on well-described examples of biologically inspired designs available in the scientific literature. These examples include Flectofin®, a hingeless flapping mechanism conceived for façade shading, and WhalePower technology, the introduction of bumps on the leading edge of airfoils to improve aerodynamic properties. Our modeling disentangles the analogical aspects of the biologically inspired design process, and highlights the expansions occurring in both knowledge bases, scientific (nonbiological) and biological, as well as the impact of these expansions in the generation of new concepts (concept partitioning). This model also shows that bioinspired design requires a special form of collaboration between engineers and biologists. Contrasting with the classic one-way transfer between biology and engineering that is assumed in the literature, the concept–knowledge framework shows that these collaborations must be “mutually inspirational” because both biological and engineering knowledge expansions are needed to reach a novel solution.


Author(s):  
Juan Carlos Márquez Cañizares ◽  
Juan-Carlos Rojas

"The use of VR technology within education is an area that has generated great interest in recent years, so this work follows that trend and contains nuances related to user-centred design education. The objective of this work is to identify students’ perceptions of the use of VR technology for ethnographic research. A group of 20 industrial design students from Tecnologico de Monterrey conducted a field investigation, which included interviews and surveys, using HMD with videos and stereoscopic images of a public park in Monterrey, Mexico. Based on the research and information analysis, areas of opportunity were identified and urban furniture proposals for the public park that place were generated. Once the design process was completed, an evaluation instrument was applied to measure, through statistical analysis, the students' perceptions of their experience using technology in the design process; gender, qualification obtained and the relevance of the technology used was also considered."


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Prabod Dharshana Munasinghe ◽  
D.G.K. Dissanayake ◽  
Angela Druckman

Purpose The process of fashion design varies between market segments, yet these variations have not yet been properly explored. This study aims to examine the fashion design process as practised at the mass-market level, as this is the most vibrant and the largest market segment in terms of production volumes and sales. Design/methodology/approach It is observed that 15 semi-structured interviews were conducted with mass-market fashion designers. Key activities of the mass-market design process were identified and a comparative analysis was conducted with the general design process. Findings The mass-market design process is found to prioritise profits rather than aesthetic aspects, with the buyer exercising more power than the designer. This hinders creativity, which, in turn, may impede a move towards more environmentally benign designs. Originality/value The clothing industry is responsible for high environmental impacts and many of these impacts arise through decisions made in the design stage. In particular, the mass-market for clothing because of its high volume of sales and fast throughput, accounts for a great deal of the impact. However, little is understood about the design process that is practised in the mass-fashion market. This paper fills the gap by developing a framework that describes the mass-market design process. Understanding the design process will enable progress to be made towards achieving the United Nations Sustainable Development Goal 12: Responsible Consumption and Production.


2013 ◽  
Vol 671-674 ◽  
pp. 496-499 ◽  
Author(s):  
Ming Yang Wang ◽  
Yun Peng Chu ◽  
Yong Yao ◽  
Yu Ping Zhu

China is a developing country, and also a quake-prone country. On the one hand is the Special national conditions that per capita energy shortage and frequent earthquakes, on the other hand is the social economy development and people's living environment requirements continue to increase, both of them raised new requirement of China’s residence system development. Light steel structure residence is energy conservation , environmental protection, safety and seismic, these unique advantages just to meet the current development of residential industry in China, so it has a good development prospect. This article start from the realistic background, around the application and development of our country’s light steel structure residence presently, mainly introduced the characteristics of light steel structure residence, the impact of construction industry, and the social benefits, environmental benefits, housing industrialization effective and comprehensive benefits it can produce.


2014 ◽  
Vol 137 (2) ◽  
Author(s):  
Martin N. Goodhand ◽  
Robert J. Miller ◽  
Hang W. Lung

An important question for a designer is how, in the design process, to deal with the small geometric variations which result from either the manufacture process or in-service deterioration. For some blade designs geometric variations will have little or no effect on the performance of a row of blades, while in others their effects can be significant. This paper shows that blade designs which are most sensitive are those which are susceptible to a distinct switch in the fluid mechanisms responsible for limiting blade performance. To demonstrate this principle, the sensitivity of compressor 2D incidence range to manufacture variations is considered. Only one switch in mechanisms was observed, the onset of flow separation at the leading edge. This switch is only sensitive to geometric variations around the leading edge, 0–3% of the suction surface. The consequence for these manufacture variations was a 10% reduction in the blade's positive incidence range. For this switch, the boundary in the design space is best defined in terms of the blade pressure distribution. Blade designs where the acceleration exceeds a critical value just downstream of the leading edge are shown to be robust to geometric variation. Two historic designs, supercritical blades and blades with sharp leading edges, though superior in design intent, are shown to sit outside this robust region and thus, in practice, perform worse. The improved understanding of the robust, region of the design space is then used to design a blade capable of a robust, 5% increase in operating incidence range.


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