Protective effect of coix seed seedling extract on 60 Co‐γ radiation‐induced oxidative stress in mice

2021 ◽  
Author(s):  
Xue Li ◽  
Juanjuan Yi ◽  
Jiaqing Zhu ◽  
Changcheng Zhao ◽  
Yan Cui ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Γ Radiation ◽  
Coix Seed ◽  
Radiation Induced

Protective effect of an antithyroid compound against γ-radiation-induced damage in human colon cancer cells

2014 ◽  
Vol 53 (3) ◽  
pp. 611-619
Author(s):  
Marina Perona ◽  
Maria A. Dagrosa ◽  
Romina Pagotto ◽  
Mariana Casal ◽  
Omar Pignataro ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Protective Effect ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Γ Radiation ◽  
Radiation Induced ◽  
Human Colon Cancer Cells

scholarly journals Protective effect of polysaccharide-protein complex from a polypore mushroom,Phellinus rimosusagainst radiation-induced oxidative stress

Redox Report ◽  
2012 ◽  
Vol 17 (1) ◽  
pp. 22-27 ◽  
Author(s):  
Jini Joseph ◽  
Sudheesh Narayana Panicker ◽  
Kainoor Krishnankutty Janardhanan
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Protein Complex ◽  
Radiation Induced

Empetrum nigrum var. japonicum Extract Suppresses γ-Ray Radiation-Induced Cell Damage via Inhibition of Oxidative Stress

2011 ◽  
Vol 39 (01) ◽  
pp. 161-170 ◽  
Author(s):  
Ki Cheon Kim ◽  
In Kyung Lee ◽  
Kyoung Ah Kang ◽  
Bum Joon Kim ◽  
Daeshin Kim ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protein Modification ◽  
Cell Damage ◽  
Membrane Lipid ◽  
Mitogen Activated Protein Kinase ◽  
Γ Radiation ◽  
Empetrum Nigrum ◽  
Mitogen Activated Protein ◽  
Radiation Induced ◽  
Cellular Dna

The ethylacetate fraction of Empetrum nigrum var. japonicum (ENE) was shown to reduce intracellular reactive oxygen species (ROS) generated by γ-radiation and activate antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), and gluthathion peroxidase (GPx). ENE protected cells against radiation-induced cellular DNA damage, membrane lipid peroxidation, and protein modification, which are the main points of radiation-induced damage. In addition, ENE recovered cell viability by inhibiting apoptosis after cells were treated with radiation. ENE treatment also reduced γ-radiation induced Bax, and caspase 9 and 3 expression in irradiated cells. However, irradiated cells with ENE recovered Bcl-2 expression, which was reduced by radiation. This anti-apoptotic effect of ENE was due to the inhibition of mitogen-activated protein kinase kinase-4 (MKK4/SEK1)-c-Jun NH2-terminal kinase (JNK) cascades induced by γ-radiation. In summary, these results suggest that ENE protects cells against γ-radiation-induced oxidative stress via the reduction of ROS and attenuation of apoptosis.

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