scholarly journals Inhibition of polymicrobial biofilm formation by saw palmetto oil, lauric acid and myristic acid

2021 ◽  
Author(s):  
Yong‐Guy Kim ◽  
Jin‐Hyung Lee ◽  
Sunyoung Park ◽  
Sanghun Kim ◽  
Jintae Lee
Keyword(s):  
Lauric Acid ◽  
Myristic Acid ◽  
Biofilm Formation ◽  
Saw Palmetto

scholarly journals Modulation of Swarming and Virulence by Fatty Acids through the RsbA Protein in Proteus mirabilis

2004 ◽  
Vol 72 (12) ◽  
pp. 6836-6845 ◽  
Author(s):  
Shwu-Jen Liaw ◽  
Hsin-Chih Lai ◽  
Won-Bo Wang
Keyword(s):  
Fatty Acids ◽  
Stearic Acid ◽  
Palmitic Acid ◽  
Proteus Mirabilis ◽  
Lauric Acid ◽  
Myristic Acid ◽  
Biofilm Formation ◽  
Saturated Fatty Acids ◽  
Extracellular Polysaccharide ◽  
Dependent Pathway

ABSTRACT After sensing external signals, Proteus mirabilis undergoes a multicellular behavior called swarming which is coordinately regulated with the expression of virulence factors. Here we report that exogenously added fatty acids could act as signals to regulate swarming in P. mirabilis. Specifically, while oleic acid enhanced swarming, some saturated fatty acids, such as lauric acid, myristic acid, palmitic acid, and stearic acid, inhibited swarming. We also found that expression of hemolysin, which has been shown to be coordinately regulated with swarming, was also inhibited by the above saturated fatty acids. Previously we identified a gene, rsbA, which may encode a histidine-containing phosphotransmitter of the bacterial two-component signaling system and act as a repressor of swarming and virulence factor expression in P. mirabilis. We found that while myristic acid, lauric acid, and palmitic acid exerted their inhibitory effect on swarming and hemolysin expression through an RsbA-dependent pathway, the inhibition by stearic acid was mediated through an RsbA-independent pathway. Biofilm formation and extracellular polysaccharide (EPS) production play an important role in P. mirabilis infection. We found that RsbA may act as a positive regulator of biofilm formation and EPS production. Myristic acid was found to slightly stimulate biofilm formation and EPS production, and this stimulation was mediated through an RsbA-dependent pathway. Together, these data suggest that fatty acids may act as environmental cues to regulate swarming and virulence in P. mirabilis and that RsbA may play an important role in this process.

scholarly journals KOMPOSISI ASAM LEMAK CACING LAUT SIASIA (SIPUNCULUS, SP) DARI PERAIRAN PANTAI PULAU NUSALAUT

2017 ◽  
Vol 4 (1) ◽  
pp. 10-16
Author(s):  
Bernita Silaban
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Stearic Acid ◽  
Eicosapentaenoic Acid ◽  
Lauric Acid ◽  
Coastal Waters ◽  
Myristic Acid ◽  
Palmitoleic Acid ◽  
Fat Content ◽  
Coastal Communities

Background: "Siasia" is a seaworm species in the phylum that includes Sipuncula Sipunculidea class. This animal has been consumed for generations by coastal communities Nusalaut Island, central mollucas but not yet universally known. Until now there has been obtained gisi complete composition. This study aimed to identify the composition of fatty acids contained in vain fresh seaworms. Methods: Seaworms vain taken from coastal waters of Negeri Titawaai and Nalahia Nusalaut Island, Central Moluccas in March 2014. The parameters analyzed include methods is sokhlet fat content and fatty acid by GC method. Results: The results showed fresh siasia fat content 1.12% of coastal waters Titawaai while 1.91% of coastal waters Nalahia. Fatty acids seaworms were identified from coastal waters Titawai  is  kaparat acid (C10: 0), lauric acid (C12: 0), myristic acid (C14: 0), palmitoleic acid (C16: 1), stearic acid (C18: 0), linolenic acid (C18: 3) acid and eicosapentaenoic (C20: 5) while the fatty acids of  seaworm vain of coastal waters Nalahia include is lauric acid (C12: 0), myristic acid (C14: 0), palmitoleic acid ( C16: 1), stearic acid (C18: 0) and eicosapentaenoic acid (C20: 3). Conclusion: The fat content of fresh siasia sea worms is 1.12% from the waters of Titawaai beach, while 1.91% of the waters of the coast of Nalahia.

scholarly journals Fat deposition of broiler chickens fed a high-fat diet contained Sauropus androgynus leaf extract plus turmeric powder

2019 ◽  
Vol 44 (4) ◽  
pp. 382
Author(s):  
K. Kususiyah ◽  
U. Santoso ◽  
Y. Fenita ◽  
A. M. H. Putranto ◽  
S. Suharyanto
Keyword(s):  
Stearic Acid ◽  
Eicosapentaenoic Acid ◽  
Palmitic Acid ◽  
Lauric Acid ◽  
Myristic Acid ◽  
High Fat Diet ◽  
Broiler Chickens ◽  
Cholesterol Content ◽  
Fat Deposition ◽  
High Fat

A factorial design was used to analyzethe influenceofSauropus androgynusleaf extract (SALE) and turmeric powder (TP) on fat deposition in broilers fed high-fat diet. The first factor was the source of fat (6% beef fat and 6% palm oil), and the second factor was SALE plus TP [0 g SALE plus 0 g TP (G1), 9 g SALE plus 0.5 g TP (G2), 18 g SALE plus 0.5 g TP (G3), 9 g SALE plus 1 g TP (G4), 18 g SALE plus 1 g TP (G5)]. SALE plus TP affected cholesterol,lauric acid, myristic acid, palmitic acid, stearic acid and eicosapentaenoic acid contents (p<0.01).Fat sources affected fat, cholesterol, lauric acid, myristic acid, palmitic acid, stearic acid and eicosapentaenoic acid (p<0.01). There was a significant interaction between the two factorson fat, cholesterol, lauric acid, palmitic acid, stearic acid, and eicosapentaenoic acid contents. In conclusion, 18 g SALE plus 1 g TP supplementation to high-fat diet resulted in lower stearic acid, but it resulted in higher eicosapentaenoic acid. Supplementation of SALEplus TPto a high-fat diet lowered cholesterol content and changed fatty acidscomposition.

scholarly journals The chemical composition of vegetable seed fats in relation to the natural orders of plants

1928 ◽  
Vol 103 (723) ◽  
pp. 111-117 ◽  
Keyword(s):  
Fatty Acids ◽  
Chemical Composition ◽  
Erucic Acid ◽  
Lauric Acid ◽  
Myristic Acid ◽  
Considerable Time ◽  
Group Frequency ◽  
Vegetable Seed ◽  
Improved Methods

Analyses, by recent and improved methods, of the mixed fatty acids from various seed fats are now available in a number of different cases, and show, more definitely than hitherto, that the seed fats of members of the same botanical group frequency possess strongly marked specific resemblances. It has been recognised, of course, for a considerable time that seed fats from plants belonging to the same or nearly allied botanical orders often contain similar, and to a certain extent specific, mixtures of fatty acids. Thus, the fats from fruits of the Palmæ are marked by the presence of relatively large quantities of lauric acid, whilst myristic acid is prominent in those of the Myristiceæ , and erucic acid in seeds of the Cruciferæ ,

scholarly journals A Method for Analyzing Fatty Acids in Cattle Hair, with Special Emphasis on Lauric Acid and Myristic Acid

2019 ◽  
Vol 121 (11) ◽  
pp. 1900143
Author(s):  
Ramona Möller ◽  
Gerd Nürnberg ◽  
Elke Albrecht ◽  
Wolfgang Ruth ◽  
Gudrun A. Brockmann ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Lauric Acid ◽  
Myristic Acid

scholarly journals The Production of Biofuels from Coconut Oil Using Microwave

2015 ◽  
Vol 9 (7) ◽  
pp. 93 ◽  
Author(s):  
A Suryanto ◽  
Suprapto Suprapto ◽  
Mahfud Mahfud
Keyword(s):  
Fatty Acids ◽  
Reaction Time ◽  
Lauric Acid ◽  
Myristic Acid ◽  
Saturated Fatty Acids ◽  
Electrical Power ◽  
Coconut Oil ◽  
Raw Material ◽  
Medium Chain ◽  
Acid Reaction

Biofuels including biodiesel, an alternative fuel, is renewable, environmentally friendly, non-toxic and lowemission energy. The raw material used in this work was coconut oil, which contained saturated fatty acids about90% with medium chain (C8-C12), especially lauric acid and myristic acid. Reaction was conducted in batchreactor assisted by microwave. The purpose of this research was to study the effect of power and NaOH catalystin transesterification enhanced by microwave and to obtain a biofuels (biodiesel and biokerosene) derived fromcoconut oil. The reaction was performed by mixing oil and methanol with mole ratio of 1:6, catalystconcentration of 1% w/w with setting electrical power at 100, 264, 400, 600 and 800 W. The reaction time wasconditioned at of 2.5, 5, 7.5, 10 and 15 min. The results showed that microwave could accelerate thetransesterification process to produce biodiesel using NaOH catalyst. The highest yield of biodiesel was 97.76 %,or 99.05 % conversion at 5 min reaction, meanwhile biokerosene was 48% after distillation.

Myristic acid supports the immediate inhibitory effect of lauric acid on ruminal methanogens and methane release

Anaerobe ◽  
2004 ◽  
Vol 10 (5) ◽  
pp. 269-276 ◽  
Author(s):  
Carla R. Soliva ◽  
Leo Meile ◽  
Ida K. Hindrichsen ◽  
Michael Kreuzer ◽  
Andrea Machmüller
Keyword(s):  
Lauric Acid ◽  
Myristic Acid ◽  
Inhibitory Effect ◽  
Methane Release

Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid

2009 ◽  
Vol 390 (4) ◽  
Author(s):  
Andy Zöllner ◽  
Calin-Aurel Dragan ◽  
Dominik Pistorius ◽  
Rolf Müller ◽  
Helge B. Bode ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Fission Yeast ◽  
Lauric Acid ◽  
Myristic Acid ◽  
Poor Prognosis ◽  
Catalytic Properties ◽  
Human Cancer ◽  
Cytochrome P450 Enzyme ◽  
P450 Enzyme ◽  
Whole Cell Biotransformation

Abstract Overexpression of human CYP4Z1, a cytochrome P450 enzyme, has been correlated with poor prognosis in human cancer. However, its catalytic properties are not yet known. We expressed this P450 in Schizosaccharomyces pombe and demonstrate by whole-cell biotransformation assays CYP4Z1-dependent in-chain hydroxylation of lauric and myristic acid, which in both cases leads to the formation of four different monohydroxylated products at positions ω-2, ω-3, ω-4, and ω-5, respectively. The CYP4Z1-expressing fission yeast should be a new valuable tool for testing cancer drugs or for the development of new prodrug strategies.

scholarly journals KOMPOSISI ASAM LEMAK CACING LAUT SIASIA (Sipunculus, SP) DARI PERAIRAN PANTAI PULAU NUSALAUT

2017 ◽  
Vol 3 (2) ◽  
pp. 107-114
Author(s):  
Bernita Br Silaban
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Stearic Acid ◽  
Eicosapentaenoic Acid ◽  
Linolenic Acid ◽  
Lauric Acid ◽  
Coastal Waters ◽  
Myristic Acid ◽  
Palmitoleic Acid ◽  
Fat Content

Background: "Siasia" is a seaworm species in the phylum that includes Sipuncula Sipunculidea class. This animal has been consumed for generations by coastal communities Nusalaut Island, central mollucas but not yet universally known. Until now there has been obtained gisi complete composition. This study aimed to identify the composition of fatty acids contained in vain fresh seaworms. Method: Seaworms vain taken from coastal waters of Negeri Titawaai and Nalahia Nusalaut Island, Central Moluccas in March 2014. The parameters analyzed include methods is sokhlet fat content and fatty acid by GC method. Result: The results showed fresh siasia fat content 1.12% of coastal waters Titawaai while 1.91% of coastal waters Nalahia. Fatty acids seaworms were identified from coastal waters Titawai  is  kaparat acid (C10: 0), lauric acid (C12: 0), myristic acid (C14: 0), palmitoleic acid (C16: 1), stearic acid (C18 : 0), linolenic acid (C18: 3) acid and eicosapentaenoic (C20: 5) while the fatty acids of  seaworm vain of coastal waters Nalahia include is lauric acid (C12: 0), myristic acid (C14: 0), palmitoleic acid ( C16: 1), stearic acid (C18: 0) and eicosapentaenoic acid (C20: 3). Conclusion: Siasia fatty acid from Titawai waters of the identified seven seas of each capsic acid (C10: 0), lauric acid (C12: 0), myristic acid (C14: 0), palmitoleic acid (C16: 1) , Stearic acid (C18: 0), linolenic acid (C18: 3) and eicosapentaenoic acid (C20: 5) whereas Siasia fatty acids from Nalahia's coastal waters were identified as five lauric acid (C12: 0), myristic acid (C14: 0), palmitoleic acid (C16: 1), stearic acid (C18: 0) and eicosapentaenoic acid (C20: 3).

scholarly journals GC-MS and Antioxidant Capacity Analysis in Propanol Extract of Carthamus tinctorious L

2021 ◽  
Vol 8 (1) ◽  
pp. 67
Author(s):  
Sri Indriati ◽  
Muhammad Yusuf ◽  
Riskayanti Riskayanti ◽  
Nur Amaliah ◽  
Mahyati Latief ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Linoleic Acid ◽  
Stearic Acid ◽  
Palmitic Acid ◽  
Lauric Acid ◽  
Myristic Acid ◽  
Capacity Analysis ◽  
Time Intervals ◽  
Maximum Extraction ◽  
Maximum Content

Safflower, were extracted using propanol solvent at different time intervals: 10, 20, and 30 min at a constant temperature of 40°C. The extracts were analyzed by GC/MS technique. The major compounds identified were tetrapentacontane, tetracontane, triacontanol, gamma sitosterol, myristic acid, linoleic acid, stearic acid, palmitic acid, oleic acid, and lauric acid. However, some levels of palmidrol, beta-amyrin, cubenol, and tocopherol were also found in safflower extracts. Most of the volatile compounds were detected between 10–30 min time of extraction. The 30 min time of extraction also showed the maximum content of polyphenols and antioxidants in safflower extracts. Thus, 30 min was suggested as the most suitable time for maximum extraction of bioactive volatiles, antioxidants, and polyphenols from Safflower using propanol solvent.

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