scholarly journals Is there an increased risk of falls and fractures in people with early diagnosed hip and knee osteoarthritis? Data from the Osteoarthritis Initiative

2016 ◽  
Vol 21 (6) ◽  
pp. 1193-1201 ◽  
Author(s):  
Toby O. Smith ◽  
Emma Higson ◽  
Matthew Pearson ◽  
Michael Mansfield
Keyword(s):  
Knee Osteoarthritis ◽  
Increased Risk ◽  
Risk Of Falls ◽  
Osteoarthritis Initiative

scholarly journals Parkinson’s Disease and Symptomatic Osteoarthritis Are Independent Risk Factors of Falls in the Elderly

2019 ◽  
Vol 12 ◽  
pp. 117954411988493 ◽  
Author(s):  
Anneli Teder-Braschinsky ◽  
Aare Märtson ◽  
Marika Rosenthal ◽  
Pille Taba
Keyword(s):  
Risk Factors ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Knee Osteoarthritis ◽  
The Elderly ◽  
Control Group ◽  
Increased Risk ◽  
Symptomatic Knee ◽  
Risk Of Falls ◽  
Risk Factors For Falls

Objectives: Deteriorating functionality and loss of mobility, resulting from Parkinson’s disease, may be worsened by osteoarthritis, which is the most common form of joint disease causing pain and functional impairment. We assessed the association between symptomatic hip or knee osteoarthritis, falls, and the ability to walk among patients with Parkinson’s disease compared to a control group. Methods: A total of 136 patients with Parkinson’s disease in Southern Estonia and 142 controls with an average age of 76.8 and 76.3 years, respectively, were enrolled in a retrospective case-control study. Information on falls and related fractures during the previous year was collected from the patients with Parkinson’s disease and controls. Covariates included gender, age, mobility, duration of Parkinson’s disease, and fractures. Results: Patients with Parkinson’s disease were at an increased risk of falls compared to the control group, and for the higher risk of fractures. Symptomatic knee or hip osteoarthritis was a significant independent predictor of falls in both patients with Parkinson’s disease and controls. The higher risk for fractures during the previous year was demonstrated in symptomatic osteoarthritis. Risk factors for falls included also female gender, use of sleep pills, and the inability to walk 500 m. Conclusions: Symptomatic hip and knee osteoarthritis are risk factors for falls and related fractures among the elderly population with and without Parkinson’s disease. The inability to walk 500 m could be used as a simple predictive factor for the increased risk of falls among elderly populations.

scholarly journals VITAMIN D SUPPLEMENTATION AND FUNCTIONAL KNEE OSTEOARTHRITIS PROGRESSION IN OLDER ADULTS WITH OBESITY: DATA FROM THE OSTEOARTHRITIS INITIATIVE

2015 ◽  
pp. 1-4
Author(s):  
A.J. Zbehlik ◽  
L.K. Barre ◽  
J.A. Batsis ◽  
E.A. Scherer ◽  
S.J. Bartels
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Knee Osteoarthritis ◽  
The Elderly ◽  
Pain Scale ◽  
Primary Outcome Measure ◽  
Vitamin D Supplementation ◽  
Womac Pain ◽  
Increased Risk ◽  
Osteoarthritis Initiative

Objective: Older adults with obesity are at increased risk of knee osteoarthritis (KOA) and vitamin D deficiency, but data on the effect of vitamin D supplementation in this population are equivocal. This study evaluated the effect of vitamin D supplementation on functional progression of KOA in older adults with obesity. Participants with Body Mass Index ≥30 kg/m2 and aged ≥ 60 years from the Osteoarthritis Initiative progression cohort were stratified by baseline vitamin D use. The relationship between vitamin D supplementation and progression of KOA at 72 months was characterized. The Western Ontario McMaster University Osteoarthritis Index (WOMAC) pain scale was the primary outcome measure. Secondary measures included: WOMAC disability, Physical Activity Scale for the Elderly, gait speed and Knee injury and Osteoarthritis Outcome Score (KOOS) scales. In older adults with KOA and obesity, baseline supplemental vitamin D use did not predict functional progression of osteoarthritis at 72 months.

scholarly journals Sarcopenic Knee Osteoarthritis: A Risk Factor for Recurrent Falls

2021 ◽  
Author(s):  
Hirotaka Iijima ◽  
Tomoki Aoyama
Keyword(s):  
Older Adults ◽  
Knee Osteoarthritis ◽  
Knee Oa ◽  
Recurrent Falls ◽  
Increased Risk ◽  
Risk Of Falls ◽  
Interactive Relationship ◽  
Falls In Older Adults ◽  
Risk Factors For Falls ◽  
And Control

Abstract Background: Sarcopenia and knee osteoarthritis (OA) are major risk factors for falls in older adults. The coexistence of these two conditions may exacerbate the risk of falls through the sarcopenia-OA interaction. This study aimed to test the hypothesis that older adults with coexisting sarcopenia and knee OA, defined as “sarcopenic OA,” displayed an increased risk of falls.Methods: Patients in an orthopedics clinic (n = 298, age: 60–90 years, 78.9% women) were divided into 4 groups according to the presence of sarcopenia and radiographic knee OA: isolated sarcopenia, isolated knee OA, sarcopenic knee OA, and control (i.e., non-sarcopenia with non-OA) groups. We used questionnaires to assess fall experience in the prior 12 months. We performed binary and ordinal logistic regression analyses to evaluate the relationship between the 4 groups and falls experience.Results: Of 298 participants, 27 (9.1%) had sarcopenic knee OA. Patients with sarcopenic knee OA had 4.70 times (95% confidence interval: 1.08, 20.5) higher odds of recurrent falls (≥ 2 falls) than those with control after adjustment for age, sex, and body mass index.Conclusions: Patients with sarcopenic knee OA displayed higher frailty. This study provides novel interactive relationship between sarcopenia and knee OA in the context of recurrent falls experience.Trial registration: Not applicable.

scholarly journals Increased recurrent falls experience in older adults with coexisting of sarcopenia and knee osteoarthritis: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hirotaka Iijima ◽  
Tomoki Aoyama
Keyword(s):  
Older Adults ◽  
Knee Osteoarthritis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Knee Oa ◽  
Recurrent Falls ◽  
Increased Risk ◽  
Risk Of Falls ◽  
Risk Factors For Falls

Abstract Background Sarcopenia and knee osteoarthritis (OA) are two major risk factors for falls in older adults. The coexistence of these two conditions may exacerbate the risk of falls. This cross-sectional study aimed to test the hypothesis that older adults with coexisting sarcopenia and knee OA displayed an increased risk of falls experience. Methods Participants recruited from an orthopedic clinic were divided into four groups according to the presence of sarcopenia and radiographic knee OA: isolated sarcopenia, isolated knee OA, sarcopenia + knee OA, and control (i.e., non-sarcopenia with non-OA) groups. We used questionnaires to assess falls experience in the prior 12 months. We performed logistic regression analyses to evaluate the relationship between the four groups and falls experience. Results Of 291 participants (age: 60–90 years, 78.7% women) included in this study, 25 (8.6%) had sarcopenia + knee OA. Participants with sarcopenia + knee OA had 4.17 times (95% confidence interval: 0.84, 20.6) higher odds of recurrent falls (≥2 falls) than controls after adjustment for age, sex, and body mass index. The increased recurrent falls experience was not clearly confirmed in participants with isolated sarcopenia and isolated knee OA. Conclusions People with coexisting of sarcopenia and knee OA displayed increased recurrent falls experience. This study suggests a new concept, “sarcopenic knee OA”, as a subgroup associated with higher risk of falls, which should be validated in future large cohort studies. Trial registration. Not applicable.

scholarly journals Risk of Knee Osteoarthritis Over 24 Months in Individuals Who Decrease Walking Speed During a 12-Month Period: Data from the Osteoarthritis Initiative

2017 ◽  
Vol 44 (8) ◽  
pp. 1265-1270 ◽  
Author(s):  
Mackenzie M. Herzog ◽  
Jeffrey B. Driban ◽  
Nicole M. Cattano ◽  
Kenneth L. Cameron ◽  
Timothy W. Tourville ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Knee Injury ◽  
Walking Speed ◽  
Exposure Period ◽  
The Elderly ◽  
Relative Increase ◽  
Increased Risk ◽  
Joint Health ◽  
Osteoarthritis Initiative ◽  
Grading Scale

Objective.To assess the association between change in walking speed over a 12-month period and risk of developing radiographic knee osteoarthritis (rKOA) over a 24-month period.Methods.We included participants without rKOA from the Osteoarthritis Initiative. Change in walking speed was determined from a 20-m walk assessment, calculated using walking speed at 12-month followup minus baseline speed and/or 24-month followup walking speed minus 12-month speed. Incident rKOA was defined as progressing to Kellgren-Lawrence arthritis grading scale ≥ 2 within 24 months (i.e., incidence between 12 and 36 mos or 24 and 48 mos). Self-reported significant knee injury during the exposure period, age, body mass index (BMI), and Physical Activity Scale for the Elderly (PASE) score were adjusted for analytically.Results.We included 2638 observations among 1460 unique participants (58% women; aged 59 ± 9 yrs, range 45–79). The mean change in walking speed over 12 months was 0.001 ± 0.13 m/s (range −0.6271 to 1.4968). About 5% of the sample (n = 122) developed rKOA over a 24-month period. After controlling for significant knee injury, age, BMI, and PASE score, we found an 8% relative increase in risk of developing rKOA for every 0.1 m/s decrease in walking speed over a 12-month period (risk ratio 1.08, 95% CI 1.00–1.15, p = 0.05).Conclusion.Evaluating change in speed over a 12-month period using a 20-m walk test may be useful in identifying individuals at increased risk of developing rKOA over the subsequent 24 months. Identification of patients at high risk for developing rKOA would allow medical providers to implement early interventions to maximize joint health.

scholarly journals Postural Stability and Proprioception Abnormalities in Patients with Knee Osteoarthritis

2021 ◽  
Vol 11 (4) ◽  
pp. 1469
Author(s):  
Luciana Labanca ◽  
Giuseppe Barone ◽  
Stefano Zaffagnini ◽  
Laura Bragonzoni ◽  
Maria Grazia Benedetti
Keyword(s):  
Knee Osteoarthritis ◽  
Postural Stability ◽  
Functional Performance ◽  
Functional Score ◽  
Functional Abilities ◽  
Knee Score ◽  
Knee Oa ◽  
Risk Of Falls ◽  
Ongoing Assessment ◽  
And Training

Knee osteoarthritis (OA) leads to the damage of all joint components, with consequent proprioceptive impairment leading to a decline in balance and an increase in the risk of falls. This study was aimed at assessing postural stability and proprioception in patients with knee OA, and the relation between the impairment in postural stability and proprioception with the severity of OA and functional performance. Thirty-eight patients with knee OA were recruited. OA severity was classified with the Kellgren–Lawrence score. Postural stability and proprioception were assessed in double- and single-limb stance, in open- and closed-eyes with an instrumented device. Functional performance was assessed using the Knee Score Society (KSS) and the Short Performance Physical Battery (SPPB). Relationships between variables were analyzed. Postural stability was reduced with respect to reference values in double-limb stance tests in all knee OA patients, while in single-stance only in females. Radiological OA severity, KSS-Functional score and SPPB were correlated with greater postural stability impairments in single-stance. Knee OA patients show decreased functional abilities and postural stability impairments. Proprioception seems to be impaired mostly in females. In conclusion, clinical management of patients with OA should include an ongoing assessment and training of proprioception and postural stability during rehabilitation.

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