Alcohol‐attributed disease burden in four Nordic countries: a comparison using the Global Burden of Disease, Injuries and Risk Factors 2013 study

OBJECTIVEThe Global Burden of Disease (GBD) is an international collaboration and the largest comprehensive investigation of global health disease burden ever conducted. It has been particularly insightful for understanding disease demographics in middle-income nations undergoing rapid development, such as Vietnam, where 6 of the top 10 causes of death are relevant to the neurosurgeon. The burden of stroke—the number one cause of death in Vietnam—is particularly impressive. Likewise, road injuries, with a disproportionate rate of traumatic brain injury, continue to increase in Vietnam following economic development. Low-back and neck pain is the number one cause of disability. Simultaneously, more patients have access to care, and healthcare spending is increased.METHODSIt is imperative that neurosurgical capital and infrastructure keep pace with Vietnam’s growth. The authors searched the existing literature for assessments of neurosurgical infrastructure or initiatives to address neurosurgical disease burden. Using GBD data, the authors also abstracted data for death by cause and prevalence of years of life lost due to disability (YLD) for common neurosurgical pathologies for Vietnam and comparison nations.RESULTSInterventions aimed at primary prevention of risk factors for neurosurgical disease and focused on the transference of self-sustainable technical skills were found to be analogous to those that have been successful in other regions. Efforts toward stroke prevention have been focused on causal risk factors. Multiple investigators have found that interventions aimed at increasing helmet use were successful in preventing traumatic brain injury. Government-led reforms and equipment donation programs have improved technical capacity. Nevertheless, Vietnam lags behind other nations in neurosurgeons per capita; cause-attributable death and YLD attributable to neurosurgical disease are considerably higher in Vietnam and middle-income nations compared to both lower-income nations and upper-income nations.CONCLUSIONSMore than two-thirds of deaths attributable to neurosurgical pathologies in Vietnam and other middle-income nations were due to stroke, and one-fifth of both cause-attributable death and YLD was associated with neurosurgical pathologies. Vietnam and other middle-income nations continue to assume a global burden of disease profile that ever more closely resembles that of developed nations, with particular cerebrovascular, neurotrauma, and spinal disease burdens, leading to exponentially increased demand for neurosurgeons that threatens to outpace the training of neurosurgeons.

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Cardiovascular disease burden attributable to dietary risk factors from 1990 to 2019: a systematic analysis of the Global Burden of Disease Study

Nutrition Metabolism and Cardiovascular Diseases ◽

10.1016/j.numecd.2021.11.012 ◽

2021 ◽

Author(s):

Caijuan Dong ◽

Xiang Bu ◽

Jing Liu ◽

Linyan Wei ◽

Aiqun Ma ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Disease ◽

Burden Of Disease ◽

Disease Burden ◽

Global Burden Of Disease ◽

Global Burden ◽

Systematic Analysis ◽

Dietary Risk Factors ◽

Dietary Risk ◽

Disease Study

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The global burden and attributable risk factors of chronic lymphocytic leukemia in 204 countries and territories from 1990 to 2019: analysis based on the global burden of disease study 2019

BioMedical Engineering OnLine ◽

10.1186/s12938-021-00973-6 ◽

2022 ◽

Vol 21 (1) ◽

Author(s):

Yiyi Yao ◽

Xiangjie Lin ◽

Fenglin Li ◽

Jie Jin ◽

Huafeng Wang

Keyword(s):

Risk Factors ◽

Chronic Lymphocytic Leukemia ◽

Burden Of Disease ◽

Disease Burden ◽

Attributable Risk ◽

Lymphocytic Leukemia ◽

Global Burden Of Disease ◽

Global Burden ◽

Epidemiological Characteristics ◽

The Impact

Abstract Background Chronic lymphocytic leukemia (CLL) is the most prevalent subtype of leukemia in Western countries, causing a substantial health burden on patients and society. Comprehensive evaluation of the epidemiological characteristics of CLL is warranted, especially in the current context of global population aging. The main objective of this study is evaluating the disease burden of CLL at global, regional, and national levels from 1990 to 2019. As secondary objectives, we studied the influence of demographic factors and performed risk factor analysis. We hope this study could provide evidence for the evaluation of the effectiveness of previous prevention strategies and the formulation of future global health policies. Results Based on data of CLL between 1990 to 2019 from the Global Burden of Disease (GBD) study 2019, we depicted the age, gender, and regional structure of the CLL burden population and described the impact of social development on the disease burden of CLL. The distribution and changing trends of attributable risk factors were also investigated. The global burden of CLL has increased dramatically. A high incidence has been achieved in males and elder people. Countries and territories with high social-demographic index (SDI) tended to have higher global burden than low-SDI region. Of risk factors, high body mass index and smoking were the major contributors for CLL-related mortality and disability adjusted life-years (DALYs). Conclusion In summary, the global CLL burden continues to rise over the past 30 years. The relocation of medical resource should be considered on a global scale. Graphical Abstract

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Burden of cardiovascular diseases attributable to risk factors in Brazil: data from the Global Burden of Disease 2019 study

European Heart Journal ◽

10.1093/eurheartj/ehab724.3141 ◽

2021 ◽

Vol 42 (Supplement_1) ◽

Author(s):

L C Brant ◽

B R Nascimento ◽

G A Veloso ◽

C S Gomes ◽

C Polanczyk ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Diseases ◽

Burden Of Disease ◽

Disease Burden ◽

Mortality Rates ◽

Global Burden Of Disease ◽

Global Burden ◽

High Systolic Blood Pressure ◽

Risk Of Death ◽

Cvd Mortality

Abstract Introduction Cardiovascular diseases (CVD) continue to be the main cause of death in Brazil, a middle-income country. As such, it is essential to understand the trends of risk factors (RFs) for CVDs in order to implement effective and tailored public policies. Purpose The present study sought to analyze the trend of RF for CVD and the disease burden attributable to these from 1990 to 2019, in Brazil and its states, based on estimates from the Global Burden of Disease Study 2019 (2019 GBD). Methods To estimate RF exposure, the Summary Exposure Value (SEV) (risk-weighted prevalence) was used, whereas for disease burden attributed to RFs, mortality and Disability-adjusted life-years (DALY) by CVD were used. For comparisons over time and between states, the age-standardized rates were considered. The sociodemographic index (SDI) was used as a marker of socioeconomic conditions. Results In 2019, 82% of CVD mortality in Brazil was attributable to RFs. For SEV, there was a reduction in smoking and environmental RFs, as well as an increase in metabolic RFs. High systolic blood pressure and dietary risks continue to be the main RFs for CVD mortality and DALY (Figure 1). While there was a decline in age-standardized mortality rates attributable to the evaluated RFs, there was also a stability or increase in crude mortality rates, with the exception of smoking. It is important to highlight the increase in the risk of death attributable to a high body mass index (BMI) (35 to 46/100,000 in habitants in 1990 and 2019). Regarding the analysis per state, SEVs and mortality attributable to RF were higher in those states with lower SDIs. Conclusion Despite the reduction in CVD mortality and DALY rates attributable to RF, the stability or increase in crude rates attributable to metabolic RFs is worrisome, requiring investments and a renewal of health policies. Funding Acknowledgement Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Health Surveillance Secretariat, Brazilian Ministry of Health Figure 1

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Trends and Risk Factors of Mortality and Disability-Adjusted Life Years for Cardiovascular Diseases from 1990 to 2017: Systematic Analysis for the Global Burden of Disease Study 2017

SSRN Electronic Journal ◽

10.2139/ssrn.3724861 ◽

2020 ◽

Author(s):

Zhenkun Wang ◽

Zhishui Chen ◽

Congyi Wang ◽

Aihua Du ◽

Hong Liu ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Diseases ◽

Burden Of Disease ◽

Global Burden Of Disease ◽

Global Burden ◽

Disability Adjusted Life Years ◽

Systematic Analysis ◽

Disability Adjusted Life ◽

Life Years ◽

Disease Study

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Completeness and quality of low back pain prevalence data in the Global Burden of Disease Study 2017

BMJ Global Health ◽

10.1136/bmjgh-2021-005847 ◽

2021 ◽

Vol 6 (5) ◽

pp. e005847

Author(s):

Mamata Tamrakar ◽

Priti Kharel ◽

Adrian Traeger ◽

Chris Maher ◽

Mary O'Keeffe ◽

...

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Burden Of Disease ◽

Disease Burden ◽

Global Burden Of Disease ◽

Global Burden ◽

Low Back ◽

Prevalence Data ◽

Pain Prevalence ◽

Acceptable Measure

IntroductionCompleteness of Global Burden of Disease (GBD) Study data is acknowledged as a limitation. To date, no study has evaluated this issue for low back pain, a leading contributor to disease burden globally.MethodsWe retrieved reports, in any language, based on citation details from the GBD 2017 study website. Pairs of raters independently extracted the following data: number of prevalence reports tallied across countries, age groups, gender and years from 1987 to 2017. We also considered if studies enrolled a representative sample and/or used an acceptable measure of low back pain.ResultsWe retrieved 488 country-level reports that provide prevalence data for 103 of 204 countries (50.5%), with most prevalence reports (61%) being for high-income countries. Only 16 countries (7.8%) have prevalence reports for each of the three decades of the GBD. Most of the reports (79%) did not use an acceptable measure of low back pain when estimating prevalence.ConclusionWe found incomplete coverage across countries and time, and limitations in the primary prevalence studies included in the GBD 2017 study. This means there is considerable uncertainty about GBD estimates of low back pain prevalence and the disease burden metrics derived from prevalence.

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