Geriatric nutritional risk index as a prognostic indicator in elderly patients with early colorectal cancer undergoing endoscopic submucosal dissection

2021 ◽  
Author(s):  
Minoru Kato ◽  
Yoshito Hayashi ◽  
Hiromu Fukuda ◽  
Shinjiro Yamaguchi ◽  
Takuya Inoue ◽  
...  



Oncotarget ◽  
2020 ◽  
Vol 11 (24) ◽  
pp. 2345-2356 ◽  
Author(s):  
Noriyuki Hirahara ◽  
Takeshi Matsubara ◽  
Yusuke Fujii ◽  
Shunsuke Kaji ◽  
Ryoji Hyakudomi ◽  
...  


2016 ◽  
Vol 20 (2) ◽  
pp. 71-77
Author(s):  
Hyun-Ju Lim ◽  
Dong-Wook Jeong ◽  
Sang-Yeoup Lee ◽  
Young-Hye Cho ◽  
Yun-Jin Kim ◽  
...  


Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5852
Author(s):  
Chun-Kai Liao ◽  
Yih-Jong Chern ◽  
Yu-Jen Hsu ◽  
Yueh-Chen Lin ◽  
Yen-Lin Yu ◽  
...  

Research on the relationship between the geriatric nutritional risk index (GNRI) and postoperative complications/oncological outcomes in elderly colorectal cancer (CRC) patients is limited. This study investigated the prognostic value of the GNRI in aged CRC patients. We retrospectively analyzed 1206 consecutive CRC patients aged over 75 years who underwent curative-intent surgery from January 2008 to December 2015 and categorized them into high GNRI (≥98) and low GNRI (<98) groups according to a receiver operating characteristic (ROC) curve analysis. Uni- and multivariate logistic regression analysis were used to explore the association of the GNRI with postoperative complications. Kaplan–Meier survival analyses and the Cox proportional hazard model were used to explore the association between GNRI and survival. We discovered that GNRI is an independent risk factor for postoperative complications (HR: 1.774, p = 0.037). Surgical site infection, wound dehiscence and pneumonia were more common in patients with GNRI < 98. Survival analysis showed significantly worse overall survival and disease-free survival in the low GNRI group (both p < 0.001). In the multivariate analysis, GNRI < 98 was an independent risk factor for OS (HR: 1.329, p = 0.031) and DFS (HR: 1.312, p = 0.034). Thus, preoperative GNRI can be effectively used to predict postoperative complications and long-term survival in elderly CRC patients after curative surgery.



2019 ◽  
Vol 73 (9) ◽  
pp. 1807
Author(s):  
Takahiro Okano ◽  
Hirohiko Motoki ◽  
Masatoshi Minamisawa ◽  
Kazuhiro Kimura ◽  
Soichiro Ebisawa ◽  
...  


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