Effects of 1‐year Treatment with Canagliflozin on Body Composition and Total Body Water in Patients with Type 2 Diabetes

2021 ◽  
Author(s):  
Ikuro Matsuba ◽  
Masahiro Takihata ◽  
Masahiko Takai ◽  
Hajime Maeda ◽  
Akira Kubota ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Composition ◽  
Total Body Water ◽  
Body Water ◽  
Total Body

scholarly journals Body composition indices and cardiovascular risk in type 2 diabetes. CV biomarkers are not related to body composition

Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 309-316 ◽  
Author(s):  
Aleksandra Markova ◽  
Mihail Boyanov ◽  
Deniz Bakalov ◽  
Adelina Tsakova
Keyword(s):  
Type 2 Diabetes ◽  
Body Composition ◽  
Fat Mass ◽  
Total Body Water ◽  
Body Water ◽  
Fat Free Mass ◽  
Cardiovascular Risks ◽  
Total Body ◽  
Cardiovascular Biomarkers

AbstractBackgroundThis study aims to explore the correlations of body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), waist-to-hip ratio (WHR) and body composition with levels of asymmetric dimethylarginine (ADMA), endothelin 1(ET-1), N-terminal brain natriuretic pro-peptide (NT-proBNP) and calculated cardiovascular risks.Methods102 women and 67 men with type 2 diabetes participated. Serum levels of NT-proBNP were measured by electro-hemi-luminescence while ELISA were used for ADMA and ET-1. Cardiovascular risks were calculated using the Framingham Risk Score (FRS), the UKPDS 2.0 and the ADVANCE risk engines. Statistical analysis was performed on an IBM SPSS 19.0.ResultsThe BMI outperformed all other indices of obesity (WC, WHtR, WHR), as well as body composition parameters (body fat%, fat mass, fat free mass and total body water) in relation to the estimated risks for coronary heart disease and stroke, based on different calculators. The correlations of the obesity indices with the serum cardiovascular biomarkers were not significant except for BMI and fat mass versus ET-1, and for fat free mass and total body water versus ADMA.ConclusionsThe WC, WHR, WHtR, BF%, FM and FFM apparently do not add significant information related to the levels of cardiovascular biomarkers or the calculated CV-risks.

BODY WATER COMPARTMENTS IN CHILDREN: CHANGES DURING GROWTH AND RELATED CHANGES IN BODY COMPOSITION

PEDIATRICS ◽  
1961 ◽  
Vol 28 (2) ◽  
pp. 169-181
Author(s):  
B. Friis-Hansen
Keyword(s):  
Body Composition ◽  
Total Body Water ◽  
Rapid Decrease ◽  
Body Water ◽  
The Other ◽  
First Year ◽  
Extracellular Water ◽  
Water Compartments ◽  
Total Body ◽  
First Year Of Life

During growth of infants and children, certain characteristic changes are found. A rapid decrease of the relative volumes of total body water and of extracellular water occurs during the first year of life, followed by a smaller decrease of volume of extracellular water later in childhood. At the same time an increased heterogeneity of the extracellular water takes place. On the other hand, the volume of intracellular water increases a little during the first months of life and remains more or less constant from then on. Formulas and nomograms from which these body water compartments can be predicted are presented. Finally, data on the corresponding changes in the total body water and in body specific gravity are discussed.

Body composition in vivo. VII. Relation between red cell volume and total body water in ewes

1965 ◽  
Vol 16 (4) ◽  
pp. 661 ◽  
Author(s):  
BA Panaretto ◽  
DA Little
Keyword(s):  
Body Composition ◽  
Cell Volume ◽  
Total Body Water ◽  
Mean Value ◽  
Body Water ◽  
Red Cell ◽  
Red Cell Volume ◽  
Total Body ◽  
Body Parameters

The relationship between total body water and red cell volume was determined in a group of non-pregnant crossbred ewes, in an endeavour to obtain a method which did not necessitate the use of radioisotopes for determining body composition. Total body water could be predicted from red cell volume. The 95% confidence interval for a mean value for total body water, predicted from the red cell volume, was ±18.8% of the mean. All other relations which can be derived between the red cell volume and other body parameters depended on this relation. The calculation of body composition from measurements of the red cell volume is discussed.

Change in Total Body Water as a Metric for Predicting Need for Outpatient Intravenous Fluids in Postoperative Bariatric Patients

2020 ◽  
Vol 86 (9) ◽  
pp. 1169-1174
Author(s):  
Lauren E. Matevish ◽  
Alexander T. Hawkins ◽  
Alva J. Bethurum ◽  
Chetan V. Aher ◽  
Wayne J. English ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Body Composition ◽  
Length Of Stay ◽  
Total Body Water ◽  
Hospital Length ◽  
Body Water ◽  
Hospital Length Of Stay ◽  
Diabetes Diagnosis ◽  
Bariatric Patients ◽  
Total Body

Background Dehydration drives a significant proportion of readmissions following bariatric surgery. Routinely performed body composition testing and total body water (TBW) calculations may present a novel method for diagnosing dehydration for outpatient intervention. We sought to determine if a change in TBW from preoperative baseline could help identify bariatric patients requiring outpatient intravenous fluid (IVF) administration for dehydration. Methods The VUMC Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program database was retroactively queried for all patients undergoing bariatric surgery at an accredited bariatric surgery center from January 1, 2017 to May 31, 2018. Body composition test results presurgery and postsurgery were extracted from the electronic health record. Change in TBW was compared between patients requiring outpatient IVF and those who did not use multivariable logistic regression. Results 583 patients underwent surgery over the study period (388 laparoscopic Roux-en-Y gastric bypass, 195 sleeve). 62 (10.6%) required outpatient fluid administration for dehydration. After multivariable analysis, patients with an increased hospital length of stay at index operation were more likely to require outpatient IVF (odds ratio [OR] 1.65, 95% CI 1.22-2.2). Preexisting diabetes diagnosis was protective (OR 0.35, 95% CI 0.16-0.74). Neither 1-week nor 1-month change in TBW from preoperative baseline was significantly different between patients receiving outpatient IVF and those who did not. Conclusion Increased hospital length of stay predicts patients at risk of postoperative dehydration requiring IVF administration. Body composition testing and TBW were not useful in distinguishing between populations. Further research is needed to examine the efficacy of outpatient IVF in preventing hospital readmissions for dehydration.

scholarly journals Measuring the body composition of elderly subjects: a comparison of methods

1994 ◽  
Vol 72 (1) ◽  
pp. 33-44 ◽  
Author(s):  
J. J. Reilly ◽  
L. A. Murray ◽  
J. Wilson ◽  
J. V. G. A. Durnin
Keyword(s):  
Body Composition ◽  
Total Body Water ◽  
Body Water ◽  
The Body ◽  
Practical Significance ◽  
Elderly Subjects ◽  
Younger Adults ◽  
Individual Level ◽  
Total Body ◽  
The Individual

There is a paucity of data on differences between methods for the assessment of body composition in elderly subjects. Studies on younger adults suggest that such differences are of some practical significance at the individual level. In the present study the following methods of estimating percentage body fatness (BF%) were compared in healthy elderly men and women (mean age 70 (SD 6) years: densitometry; skinfold thickness; total body water; bioelectrical impedance (BIA) using an age-specific predictive equation and the manufacturers' equation; body mass index (BMI). Though BF% estimates from the various methods tended to be highly correlated with those from densitometry and with each other, differences between methods at the individual level were marked. In particular, the age-specific equations based on BMI and BIA systematically overestimated BF% relative to the other methods. Biases between BF% estimates derived from densitometry, skinfolds, BIA (manufacturers' equation) and total body water were less marked, indicating little evidence of systematic differences between these methods in elderly subjects. Individual differences between methods were slightly greater than those reported in some studies of younger adults, but this may be of little practical significance, and may be considered inevitable in view of variability between and within subjects in the extent to which the underlying assumptions of these two-component methods are met in elderly subjects.

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