Real‐life experience with oral oxybutynin long‐term continuous therapy in severe hyperhidrosis and systematic review of the literature

2021 ◽  
Vol 34 (2) ◽  
Author(s):  
Giulia Briatico ◽  
Riccardo Pampena ◽  
Elisabetta Fulgione ◽  
Graziella Babino ◽  
Caterina Mariarosaria Giorgio ◽  
...  
Keyword(s):  
Systematic Review ◽  
Life Experience ◽  
Real Life ◽  
Review Of The Literature ◽  
Continuous Therapy

scholarly journals Efficacy of Surgery for the Treatment of Gastric Cancer Liver Metastases: A Systematic Review of the Literature and Meta-Analysis of Prognostic Factors

2021 ◽  
Vol 10 (5) ◽  
pp. 1141
Author(s):  
Gianpaolo Marte ◽  
Andrea Tufo ◽  
Francesca Steccanella ◽  
Ester Marra ◽  
Piera Federico ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Systematic Review ◽  
Prognostic Factors ◽  
Liver Metastases ◽  
Meta Analysis ◽  
Multidisciplinary Treatment ◽  
Review Of The Literature ◽  
Term Survival ◽  
The Impact

Background: In the last 10 years, the management of patients with gastric cancer liver metastases (GCLM) has changed from chemotherapy alone, towards a multidisciplinary treatment with liver surgery playing a leading role. The aim of this systematic review and meta-analysis is to assess the efficacy of hepatectomy for GCLM and to analyze the impact of related prognostic factors on long-term outcomes. Methods: The databases PubMed (Medline), EMBASE, and Google Scholar were searched for relevant articles from January 2010 to September 2020. We included prospective and retrospective studies that reported the outcomes after hepatectomy for GCLM. A systematic review of the literature and meta-analysis of prognostic factors was performed. Results: We included 40 studies, including 1573 participants who underwent hepatic resection for GCLM. Post-operative morbidity and 30-day mortality rates were 24.7% and 1.6%, respectively. One-year, 3-years, and 5-years overall survival (OS) were 72%, 37%, and 26%, respectively. The 1-year, 3-years, and 5-years disease-free survival (DFS) were 44%, 24%, and 22%, respectively. Well-moderately differentiated tumors, pT1–2 and pN0–1 adenocarcinoma, R0 resection, the presence of solitary metastasis, unilobar metastases, metachronous metastasis, and chemotherapy were all strongly positively associated to better OS and DFS. Conclusion: In the present study, we demonstrated that hepatectomy for GCLM is feasible and provides benefits in terms of long-term survival. Identification of patient subgroups that could benefit from surgical treatment is mandatory in a multidisciplinary setting.

Fall risk assessment tools for use among older adults in long-term care settings: A systematic review of the literature

2017 ◽  
Vol 37 (1) ◽  
pp. 23-33 ◽  
Author(s):  
Susan Nunan ◽  
Christine Brown Wilson ◽  
Timothy Henwood ◽  
Deborah Parker
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Risk Assessment ◽  
Fall Risk ◽  
Long Term Care ◽  
Assessment Tools ◽  
Review Of The Literature ◽  
Term Care ◽  
Risk Assessment Tools

scholarly journals Long-term Outcomes After Facial Allotransplantation: Systematic Review of the Literature

2020 ◽  
Vol 8 (9S) ◽  
pp. 116-117
Author(s):  
Bianief Tchiloemba ◽  
Martin Kauke ◽  
Valentin Haug ◽  
Obada Abdulrazzak ◽  
Ali-Farid Safi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Review Of The Literature ◽  
Long Term Outcomes

Sustained response to long-term biologics and switching in psoriatic arthritis: results from real life experience

2007 ◽  
Vol 67 (5) ◽  
pp. 717-719 ◽  
Author(s):  
L C Coates ◽  
L S Cawkwell ◽  
N W F Ng ◽  
A N Bennett ◽  
D J Bryer ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Life Experience ◽  
Real Life ◽  
Sustained Response

Biologics registries

2013 ◽  
pp. 257-263
Author(s):  
David Isenberg ◽  
Angela Zink
Keyword(s):  
Rheumatoid Arthritis ◽  
Life Experience ◽  
Real Life ◽  
Cancer Development ◽  
Controlled Trials ◽  
Side Effect Profile ◽  
Risk Of Infection ◽  
Biologic Drugs ◽  
Double Blind

Double-blind controlled trials undertaken over the past two decades have established the short-term effectiveness and side-effect profile of biologic drugs for patients with rheumatoid arthritis and related diseases. However, the development of biologics registers to capture ’real-life experience’ and explore long-term effectiveness and complications is equally important. In this chapter, we demonstrate how these registers have identified long-term joint benefits, a reduction in cardiovascular mortality, reassurance concerning fears about cancer development, and a balanced view of the risk of infection.

Everolimus and long-term decline in renal function after liver transplantation: real-life experience with measured GFR

2020 ◽  
Vol 55 (6) ◽  
pp. 718-724
Author(s):  
Fredrik Åberg ◽  
John Berntsson ◽  
Gustaf Herlenius ◽  
Maria Castedal ◽  
William Bennet
Keyword(s):  
Liver Transplantation ◽  
Renal Function ◽  
Life Experience ◽  
Real Life ◽  
Measured Gfr

scholarly journals P559 Real-life experience with long-term maintenance of golimumab in ulcerative colitis patients

2019 ◽  
Vol 13 (Supplement_1) ◽  
pp. S393-S394
Author(s):  
M Iborra ◽  
N García-Morales ◽  
S Rubio ◽  
O Nantes Castillejo ◽  
F Bertoletti ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Life Experience ◽  
Real Life ◽  
Term Maintenance

Staff Factors Contributing to Family Satisfaction with Long-Term Dementia Care: A Systematic Review of the Literature

2016 ◽  
Vol 40 (5) ◽  
pp. 326-351 ◽  
Author(s):  
Katharine Law ◽  
Tom G. Patterson ◽  
Jane Muers
Keyword(s):  
Systematic Review ◽  
Family Satisfaction ◽  
Dementia Care ◽  
Review Of The Literature

scholarly journals Long-term outcomes of acromegaly treated with fractionated stereotactic radiation: case series and literature review

2017 ◽  
Vol 4 (4) ◽  
pp. 255-262
Author(s):  
Ryan Rhome ◽  
Isabelle M Germano ◽  
Ren-Dih Sheu ◽  
Sheryl Green
Keyword(s):  
Systematic Review ◽  
Literature Review ◽  
Case Series ◽  
Tumor Control ◽  
Pituitary Neoplasms ◽  
Review Of The Literature ◽  
Biochemical Control ◽  
Low Incidence

Abstract Background Growth hormone (GH)-secreting pituitary adenomas represent an uncommon subset of pituitary neoplasms. Stereotactic radiosurgery (SRS) and fractionated stereotactic radiotherapy (FSRT) have been used as primary or adjuvant treatment. The purpose of this study is to report the long-term tumor control and toxicity from our institution and to perform a systematic literature review of acromegaly patients treated with FSRT. Methods We retrospectively reviewed all patients treated with FSRT (median dose 50.4 Gray [Gy], range 50.4–54 Gy) between 2005 and 2012 who had: 1) GH-secreting adenoma with persistently elevated insulin growth factor-1 (IGF-1) despite medical therapy and 2) clinical follow up >3 years after FSRT. Patients were treated with modern FSRT planning techniques. Biochemical control was defined as IGF-1 normalization. Systematic review of the literature was performed for FSRT in acromegaly. Results With a median follow-up of 80 months, radiographic control was achieved in all 11 patients and overall survival was 100%. Long-term biochemical control was achieved in 10 patients (90.9%) with either FSRT alone (36.4%) or FSRT with continued medical management (45.5%). No patient experienced new hypopituitarism, cranial nerve dysfunctions, or visual deficits. Our systematic review found published rates of biochemical control and hypopituitarism vary, with uniformly good radiographic control and low incidence of visual changes. Conclusions Adjuvant FSRT offered effective long-term biochemical control and radiographic control, and there was a lower rate of complications in this current series. Review of the literature shows variations in published rates of biochemical control after FSRT for acromegaly, but low incidence of serious toxicities.

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