Excellent response to 1% benvitimod cream in a 9‐year‐old girl with vulvar psoriasis

2022 ◽  
Author(s):  
Liangjiao Dong ◽  
Qian Li ◽  
Guangming Chen ◽  
Sanquan Zhang ◽  
Jingyao Liang ◽  
...  
Keyword(s):  
2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Parigini Aníbal María ◽  
Diego María Clara de ◽  
Beguerie Julieta Ruiz ◽  
Paredes Victoria Duran ◽  
Anaya Javier

Author(s):  
Domenico Albano ◽  
Francesco Dondi ◽  
Valentina Zilioli ◽  
Maria Beatrice Panarotto ◽  
Alessandro Galani ◽  
...  

Abstract Objective The baseline treatment of differentiated thyroid cancer (DTC) consists of thyroidectomy followed by postoperative risk-adapted radioiodine therapy (RAIT) when indicated. The choice of most appropriate RAI activities to administer with the aim to reach an efficient remnant ablation and reduce the risk of recurrence is yet an open issue and the detection of basal factors that may predict treatment response seems fundamental. The aim of this study was to investigate the potential role of Hashimoto thyroiditis (HT) in predicting 1-year and 5-year treatment response after RAIT and prognosis. Methods We retrospectively included 314 consecutive patients (174 low-risk and 140 intermediate-risk) who received thyroidectomy plus RAIT. One-year and 5-year disease status was evaluated according to 2015 ATA categories response based upon biochemical and structural findings. Results HT was reported histopathologically in 120 patients (38%). DTC patients with concomitant HT received a higher number of RAITs and cumulative RAI activities. Initial RAIT reached an excellent response in 63% after one year and 84% after 5 years. The rate of excellent response one year and 5-year after first RAIT was significantly lower in HT groups, compared to not HT (p < 0.001). Instead, HT did not have a prognostic role considering PFS and OS; while stimulate thyroglobulin (sTg) at ablation was significantly related to survival. Conclusions HT may affect the efficacy of RAIT in low to intermediate risk DTC, particularly reducing the successful rate of excellent response after RAIT. Instead, HT did not have a prognostic impact such as stimulated sTg.


2011 ◽  
Vol 27 (3) ◽  
pp. 162-163 ◽  
Author(s):  
Laura Cuesta Montero ◽  
Isabel Belinchón ◽  
Fernando Toledo ◽  
Isabel Betlloch

2021 ◽  
pp. 797-801
Author(s):  
Quang Tien Nguyen ◽  
Anh Tuan Pham ◽  
Thuy Thi Nguyen ◽  
Tam Thi Thanh Nguyen ◽  
Ky Van Le

Pulmonary angiosarcoma is a rare clinical entity with a poor prognosis and no established therapeutic strategies. We present the first case to our knowledge of metastatic pulmonary angiosarcoma, treated with checkpoint inhibitor immunotherapy, and have an excellent response. Until now, patient has been treated with immunotherapy for 1 year, and his disease is stable and well-tolerated.


2011 ◽  
Vol 26 (6) ◽  
pp. 323-328 ◽  
Author(s):  
Lars Vedel Kessing ◽  
Gunnar Hellmund ◽  
Per Kragh Andersen
Keyword(s):  

1989 ◽  
Vol 17 (2) ◽  
pp. 150-156 ◽  
Author(s):  
C. H. Banov

This 1 week study compared the efficacy of once daily administration of 10 mg loratadine with 120 mg terfenadine in out-patients with seasonal allergic rhinitis. It focussed on the efficacy of treatment at the end of the 24 h period following a daily dose. The study was designed as a double-blind, randomized, parallel-group trial, and 41 patients were enrolled and evaluated for efficacy. Patients took an initial dose at the study site and returned on days 2 and 8. At day 2 (24 h after the initial dose), according to the physician's evaluation 57% of loratadine-treated patients had a good or excellent response, compared to 50% of those given terfenadine. At day 8, 24 h after the final dose, 71% of the loratadine-treated patients and 35% of the terfenadine-treated patients had a good or excellent response ( P = 0.03). At days 2 and 8, reductions in mean symptom scores measured 22, 23 and 24 h after the initial and final doses showed an indication of being greater with loratadine than with terfenadine (non-significant due to small sample size). The incidence of sedation was similar in both groups. It is concluded that 10 mg loratadine, administered once daily, controls the symptoms of rhinitis more effectively than 120 mg terfenadine given once daily in the last few hours of the 24 h dosing period.


Author(s):  
Erlan A Simarmata . ◽  
Gede Saindra Santyadiputra, S.T., M.Cs . ◽  
Dr. Dewa Gede Hendra Divayana, S.Kom., M .

Penelitian ini bertujuan (1) Untuk mengimplementasikan Pengembangan E-modul Pada Mata Pelajaran Pemrograman Desktop Kelas XI Rekayasa Perangkat Lunak di SMK Negeri 2 Tabanan. (2) Untuk mengetahui respon siswa dan guru terhadap Pengembangan E-modul Pada Mata Pelajaran Pemrograman Desktop Kelas XI dengan Model Project Based Learning di SMK Negeri 2 Tabanan. Metode penelitian yang digunakan dalam penelitian ini adalah research and development (R&D), dengan model pengembangan Dick & Carey. Subjek penelitian ini yaitu siswa kelas XI Rekayasa Perangkat Lunak dan guru mata pelajaran Pemrograman Desktop di SMK Negeri 2 Tabanan tahun ajaran 2016/2017. Untuk mengetahui respon siswa dan guru terhadap e-modul diperoleh dengan menggunakan metode angket. Hasil penelitian menunjukkan bahwa: 1) Hasil implementasi e-modul yang telah dikembangkan pada mata pelajaran pemrograman desktop untuk siswa kelas XI Rekayasa Perangkat Lunak dengan menggunakan model pembelajaran Project Based Learning di SMK Negeri 2 Tabanan dinyatakan berhasil diterapkan berdasarkan beberapa uji yang dilakukan. 2) Hasil analisis data respon siswa menunjukkan bahwa persentase siswa yang memberikan respon sangat baik sebesar 36.84%, persentase siswa yang memberikan respon baik sebesar 63.16%, dan tidak ada siswa yang memberikan respon cukup, kurang, maupun sangat kurang dan mendapatkan presentase tingkat pencapaian e-modul sebesar 87.58%. Sedangkan hasil analisis data respon guru menunjukkan bahwa persentase guru yang memberikan respon sangat baik sebesar 94%. Kata Kunci : E-modul, Pemrograman Desktop, Model Project Based Learning, Research and Development The aim of this study is to (1) Implement the development of E-module for Desktop Progamming learning lesson of grade XI with Project Based Learning Model in SMK Negeri 2 Tabanan. (2) To know students’ and teachers’ response towards the development of E-module for Desktop Progamming learning lesson of grade XI with Project Based Learning Model in SMK Negeri 2 Tabanan. Research methodology that is used for this research was Research and Development (R&D), with Dick & Carey development model. The subject of this research was the third grade students, engineer software and Desktop Progamming teachers of SMK Negeri 2 Tabanan in Academic Year 2016/2017. To know students’ and teachers’ response towards the E-module was gained by using inquiry method. The result of this study showed that: (1) Implementation result of E-module which was developed for Desktop Progamming learning lesson of grade XI engineer software by using Project Based Learning Model in SMK Negeri 2 Tabanan has proven effective to be applied through some tests. (2) The data analysis result of students’ response showed that the percentage of students’ who give excellent response was 36.84%, students who gave good response were 63.16%, and there were no students who gave fair response, inadequate or inacceptable response and get a percentage of the level of achievement of the e-module were 87.58%. While the data analysis result of teachers’ response showed that the percentage of teaches who gave excellent response was 94%.keyword : E-Module, Desktop Progamming, project based learning, Research and Development


2016 ◽  
Vol 7 (2) ◽  
pp. 269 ◽  
Author(s):  
Suhasini Gazula ◽  
JonathanTheodore Gondi ◽  
A Rajasekhar ◽  
G Usharani

Sign in / Sign up

Export Citation Format

Share Document