scholarly journals Protective effects of an extract of the freshwater microalga Scenedesmus rubescens on UV-irradiated skin cells

2018 ◽  
Vol 40 (2) ◽  
pp. 187-192 ◽  
Author(s):  
R. Campiche ◽  
P. Sandau ◽  
E. Kurth ◽  
M. Massironi ◽  
D. Imfeld ◽  
...  
Keyword(s):  
Protective Effects ◽  
Skin Cells ◽  
Scenedesmus Rubescens

scholarly journals Combined Effects of Carotenoids and Polyphenols in Balancing the Response of Skin Cells to UV Irradiation

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1931
Author(s):  
Glenda Calniquer ◽  
Marina Khanin ◽  
Hilla Ovadia ◽  
Karin Linnewiel-Hermoni ◽  
David Stepensky ◽  
...  
Keyword(s):  
Cell Damage ◽  
Plasma Concentrations ◽  
Dermal Fibroblasts ◽  
Carnosic Acid ◽  
Rosemary Extract ◽  
Protective Effects ◽  
Skin Cells ◽  
Tomato Extract ◽  
Clinical Experiments

Oral carotenoids and polyphenols have been suggested to induce photo-protective effects. The aim of the study was to test whether the combination of carotenoids and polyphenols produce greater protective effects from UV-induced damage to skin cells. Such damage is characterized by inflammation and oxidative stress; thus, the photo-protective effect can be partially explained by modulating the nuclear factor kappa B (NFκB) and antioxidant response element/Nrf2 (ARE/Nrf2) transcription systems, known as important regulators of these two processes. Indeed, it was found in keratinocytes that carotenoids and polyphenols inhibit UVB-induced NFκB activity and release of cytokine IL-6. A combination of tomato extract with rosemary extract inhibited UVB-induced release of IL-6 more than each of the compounds alone. Moreover, this combination synergistically activated ARE/Nrf2 transcription systems. Inflammatory cytokines such as IL-6 and TNFα induce the expression of matrix metalloproteinases (MMPs), which leads to collagen breakdown; thus, it is important to note that carnosic acid reduced TNFα-induced MMP-1 secretion from human dermal fibroblasts. The in vitro results suggest beneficial effects of phytonutrient combinations on skin health. To assure that clinical experiments to prove such effects in humans are feasible, the human bioavailability of carotenoids from tomato extract was tested, and nearly a twofold increase in their plasma concentrations was detected. This study demonstrates that carotenoids and polyphenols cooperate in balancing UV-induced skin cell damage, and suggests that NFκB and ARE/Nrf2 are involved in these effects.

Protective Effects of Titanium Dioxide-based Emulsion after Short-term and Long-term Infrared-A Ray Irradiation on Skin Cells

2021 ◽  
Vol 26 (4) ◽  
pp. 595-605
Author(s):  
Jun Yeong Kim ◽  
Su Ji Kim ◽  
Gayeon You ◽  
Eun Seo Choi ◽  
Joo Hang Lee ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Protective Effects ◽  
Short Term ◽  
Skin Cells

Protective Effects of Curcumin against Oxidative Damage on Skin Cells In Vitro: Its Implication for Wound Healing

2001 ◽  
Vol 51 (5) ◽  
pp. 927-931 ◽  
Author(s):  
Toan-Thang Phan ◽  
Patrick See ◽  
Seng-Teik Lee ◽  
Sui-Yung Chan
Keyword(s):  
Wound Healing ◽  
Oxidative Damage ◽  
Protective Effects ◽  
Skin Cells

scholarly journals Antioxidant and Cellular Protective Effects against Oxidative Stress of Calendula officinalis Flowers Extracts in Human Skin Cells

2016 ◽  
Vol 27 (6) ◽  
pp. 620-626 ◽  
Author(s):  
Song Hua Xuan ◽  
Ga Yoon Kim ◽  
Ji Yeon Yu ◽  
Jee Won Kim ◽  
Ye Rim Yang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Human Skin ◽  
Protective Effects ◽  
Calendula Officinalis ◽  
Skin Cells ◽  
Human Skin Cells

scholarly journals Cytoprotective Effect of Ascorbic Acid and Rutin against Oxidative Changes in the Proteome of Skin Fibroblasts Cultured in a Three-Dimensional System

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1074 ◽  
Author(s):  
Agnieszka Gęgotek ◽  
Iwona Jarocka-Karpowicz ◽  
Elżbieta Skrzydlewska
Keyword(s):  
Ascorbic Acid ◽  
Uv Radiation ◽  
Three Dimensional ◽  
Skin Fibroblasts ◽  
Combined Effect ◽  
Dimensional System ◽  
Protective Effects ◽  
Skin Damage ◽  
Skin Cells ◽  
Extracellular Signaling

The combination of ascorbic acid and rutin, commonly used in oral preparations for their antioxidant and anti-inflammatory properties, can also be used to protect skin cells from the effects of UV radiation in sunlight. Here, we tested the potential protective effect of ascorbic acid and rutin used together in UVB-irradiated human skin fibroblasts, and assessed the proteomic profile of these cells, grown in a three-dimensional (3D) system. Proteomic findings revealed a combined effect of ascorbic acid and rutin in UV-irradiated fibroblasts against overexpression of pro-inflammatory signaling proteins and DNA reorganization/expression. These effects were not observed when cells were treated with either compounds alone. The antioxidant effects of ascorbic acid and rutin also prevented protein modifications by lipid peroxidation products. Further, ascorbic acid stimulated rutin-protein adduct formation, which supports intra/extracellular signaling and the Nrf2/ARE antioxidant pathway, contributing to the protective effects against UV-induced oxidative stress. The combined effect of ascorbic acid and rutin suggests that this combination of compounds is potentially effective against skin damage caused by UV radiation.

Protective effects of Lagerstroemia speciosa extract against UV-A damage on skin cells

2018 ◽  
Vol 124 ◽  
pp. 9-19 ◽  
Author(s):  
Panjapa Kolakul ◽  
Bungorn Sripanidkulchai
Keyword(s):  
Protective Effects ◽  
Lagerstroemia Speciosa ◽  
Skin Cells

Protective effects of a Ficus deltoidea (Mas cotek) extract against UVB-induced photoageing in skin cells

2013 ◽  
Vol 18 (1) ◽  
pp. 185-193 ◽  
Author(s):  
Rosnani Hasham ◽  
Hyun-Kyung Choi ◽  
Mohamad Roji Sarmidi ◽  
Chang-Seo Park
Keyword(s):  
Protective Effects ◽  
Ficus Deltoidea ◽  
Skin Cells

scholarly journals Local Epidermal Endocrine Estrogen Protects Human Melanocytes against Oxidative Stress, a Novel Insight into Vitiligo Pathology

2020 ◽  
Vol 22 (1) ◽  
pp. 269
Author(s):  
Asako Yamamoto ◽  
Lingli Yang ◽  
Yasutaka Kuroda ◽  
Jiao Guo ◽  
Lanting Teng ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Estrogen Receptor ◽  
The Body ◽  
Receptor Expression ◽  
Epidermal Keratinocytes ◽  
Protective Effects ◽  
Skin Cells ◽  
Healthy Donors ◽  
Estrogen Synthesis ◽  
Current Therapies

As the outermost barrier of the body, skin is a major target of oxidative stress. In the brain, estrogen has been reported synthesized locally and protects neurons from oxidative stress. Here, we explored whether estrogen is also locally synthesized in the skin to protect from oxidative stress and whether aberrant local estrogen synthesis is involved in skin disorders. Enzymes and estrogen receptor expression in skin cells were examined first by quantitative real-time PCR and Western blot analyses. Interestingly, the estrogen synthesis enzyme was mainly localized in epidermal keratinocytes and estrogen receptors were mainly expressed in melanocytes among 13 kinds of cultured human skin cells. The most abundant estrogen synthesis enzyme expressed in the epidermis was 17β-hydroxysteroid dehydrogenase 1 (HSD17β1) localized in keratinocytes, and the most dominant estrogen receptor expressed in the epidermis was G protein-coupled estrogen receptor 1 (GPER1) in melanocytes. To investigate whether keratinocyte-derived estradiol could protect melanocytes from oxidative stress, cultured human primary epidermal melanocytes (HEMn-MPs) were treated with H2O2 in the presence or absence of 17β estradiol or co-cultured with HSD17β1 siRNA-transfected keratinocytes. Keratinocyte-derived estradiol exhibited protective effects against H2O2-induced cell death. Further, reduced expression of HSD17β1 in the epidermis of skin from vitiligo patients was observed compared to the skin from healthy donors or in the normal portions of the skin in vitiligo patients. Our results suggest a possible new target for interventions that may be used in combination with current therapies for patients with vitiligo.

Pyrotechnic Residues in Gunshot Residue Analysis

1985 ◽  
Vol 43 ◽  
pp. 128-129
Author(s):  
H. M. Sagara ◽  
S. A. Schliebe ◽  
M. C. Kong
Keyword(s):  
Law Enforcement ◽  
Residue Analysis ◽  
Gunshot Residue ◽  
Particle Analysis ◽  
Dry Skin ◽  
X Ray ◽  
Skin Cells ◽  
Smokeless Powder ◽  
Carbon Coated ◽  
Detailed List

Particle analysis by scanning electron microscopy with energy-dispersive x- ray analysis is one of the current methods used in crime laboratories to aid law enforcement in identifying individuals who have recently fired or handled a firearm. During the discharge of a firearm, the high pressure caused by the detonation of the cartridge materials forces a portion of the generated gases through leaks in the firing mechanism of the weapon. These gases contain residues of smokeless powder, primer mixture, and contributions from the projectile itself. The condensation of these hot gases form discrete, micrometer-sized particles, which can be collected, along with dry skin cells, salts, and other hand debris, from the hands of a shooter by a simple adhesive lift technique. The examination of the carbon-coated adhesive lifts consist of time consuming systematic searches for high contrast particles of spherical morphology with the characteristic elemental composition of antimony, barium and lead. A detailed list of the elemental compositions which match the criteria for gunshot residue are discussed in the Aerospace report.

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