Sublingual immunotherapy with Dermatophagoides farinae drops for pediatric atopic dermatitis

2021 ◽  
Author(s):  
Chaodi Huang ◽  
Jianping Tang
Keyword(s):  
Atopic Dermatitis ◽  
Sublingual Immunotherapy ◽  
Dermatophagoides Farinae

A Retrospective Cohort Study of Sublingual Immunotherapy with Standardized Dermatophagoides farinae Drops for Allergic Rhinitis

2021 ◽  
Author(s):  
Xingkai Ma ◽  
Yu Zhang ◽  
Xiaodan Gu ◽  
Geping Wu ◽  
Jianyong Liu ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Sublingual Immunotherapy ◽  
Dermatophagoides Farinae

scholarly journals Gomisin M2 Ameliorates Atopic Dermatitis-like Skin Lesions via Inhibition of STAT1 and NF-κB Activation in 2,4-Dinitrochlorobenzene/Dermatophagoides farinae Extract-Induced BALB/c Mice

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4409
Author(s):  
Jinjoo Kang ◽  
Soyoung Lee ◽  
Namkyung Kim ◽  
Hima Dhakal ◽  
Taeg-Kyu Kwon ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Oral Administration ◽  
Skin Diseases ◽  
Nuclear Translocation ◽  
Skin Lesions ◽  
Biologically Active ◽  
Therapeutic Effects ◽  
Dermatophagoides Farinae ◽  
Tnf Α ◽  
Ifn Γ

The extracts of Schisandra chinensis (Turcz.) Baill. (Schisandraceae) have various therapeutic effects, including inflammation and allergy. In this study, gomisin M2 (GM2) was isolated from S. chinensis and its beneficial effects were assessed against atopic dermatitis (AD). We evaluated the therapeutic effects of GM2 on 2,4-dinitrochlorobenzene (DNCB) and Dermatophagoides farinae extract (DFE)-induced AD-like skin lesions with BALB/c mice ears and within the tumor necrosis factor (TNF)-α and interferon (IFN)-γ-stimulated keratinocytes. The oral administration of GM2 resulted in reduced epidermal and dermal thickness, infiltration of tissue eosinophils, mast cells, and helper T cells in AD-like lesions. GM2 suppressed the expression of IL-1β, IL-4, IL-5, IL-6, IL-12a, and TSLP in ear tissue and the expression of IFN-γ, IL-4, and IL-17A in auricular lymph nodes. GM2 also inhibited STAT1 and NF-κB phosphorylation in DNCB/DFE-induced AD-like lesions. The oral administration of GM2 reduced levels of IgE (DFE-specific and total) and IgG2a in the mice sera, as well as protein levels of IL-4, IL-6, and TSLP in ear tissues. In TNF-α/IFN-γ-stimulated keratinocytes, GM2 significantly inhibited IL-1β, IL-6, CXCL8, and CCL22 through the suppression of STAT1 phosphorylation and the nuclear translocation of NF-κB. Taken together, these results indicate that GM2 is a biologically active compound that exhibits inhibitory effects on skin inflammation and suggests that GM2 might serve as a remedy in inflammatory skin diseases, specifically on AD.

scholarly journals 306 Efficacy of Dermatophagoides farinae -specific subcutaneous immunotherapy for mouse atopic dermatitis model

2016 ◽  
Vol 136 (9) ◽  
pp. S213
Author(s):  
S. Kim ◽  
J. Shin ◽  
J. Noh ◽  
C. Park ◽  
J. Kim ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Subcutaneous Immunotherapy ◽  
Dermatophagoides Farinae

scholarly journals Efficacy of Hataedock Treatments for Maintenance and Formation of Lipid Barrier in Obese NC/Nga Mice with Dermatophagoides Farinae-Induced Atopic Dermatitis

2018 ◽  
Vol 39 (4) ◽  
pp. 74-85
Author(s):  
Hee-Yeon Kim ◽  
Sang-Hyun Ahn ◽  
In-Jun Yang ◽  
Jin-Hong Cheon ◽  
Kibong Kim
Keyword(s):  
Atopic Dermatitis ◽  
Dermatophagoides Farinae

Hataedock treatment has preventive therapeutic effects for atopic dermatitis through skin barrier protection in Dermatophagoides farinae -induced NC/Nga mice

2017 ◽  
Vol 206 ◽  
pp. 327-336 ◽  
Author(s):  
Ho-Yeol Cha ◽  
Sang-hyun Ahn ◽  
Jin-Hong Cheon ◽  
Sun-Young Park ◽  
Kibong Kim
Keyword(s):  
Atopic Dermatitis ◽  
Skin Barrier ◽  
Therapeutic Effects ◽  
Dermatophagoides Farinae

A comparative study of subcutaneous, intralymphatic and sublingual immunotherapy for the long‐term control of dogs with nonseasonal atopic dermatitis

2020 ◽  
Vol 31 (5) ◽  
pp. 365
Author(s):  
Nina M. Fischer ◽  
Ana Rostaher ◽  
Claude Favrot
Keyword(s):  
Atopic Dermatitis ◽  
Comparative Study ◽  
Sublingual Immunotherapy

Prevalence and features of canine atopic dermatitis in Hungary

2006 ◽  
Vol 54 (3) ◽  
pp. 353-366 ◽  
Author(s):  
Noémi Tarpataki ◽  
Kinga Pápa ◽  
J. Reiczigel ◽  
P. Vajdovich ◽  
K. Vörös
Keyword(s):  
Atopic Dermatitis ◽  
Age Of Onset ◽  
Skin Testing ◽  
Large City ◽  
Clinical Signs ◽  
House Dust Mites ◽  
Dust Mites ◽  
Dermatophagoides Farinae ◽  
Doberman Pinscher ◽  
French Bulldog

Medical records of 600 dogs diagnosed with atopic dermatitis were reviewed and evaluated with reference to history, geographical distribution, breed predilection, clinical signs and positive reactions to allergens as determined by intradermal skin testing (IDT) manufactured by Artuvetrin Laboratories**. In 66.6% of dogs, the age of onset of atopic dermatitis was between 4 months and 3 years. Dogs living in the garden suburb of Budapest were more sensitive to house dust mites, fleas and moulds, and dogs from the western part of Hungary were more sensitive to weeds than to other allergens (p < 0.01). Positive reactions were most common to Dermatophagoides farinae followed by human dander. The breed distribution found in the present study was consistent with that reported in the literature, except for the breeds Hungarian Vizsla, Pumi, French bulldog, Doberman Pinscher and Bobtail which were over-represented among atopic dogs compared to the breed distribution of the general dog population of a large city in Hungary. Breeds with verified adverse reaction to food were Cocker spaniels, French bulldogs, Bullmastiffs, Bull terriers, St. Bernards, Tervurens, West Highland White terriers and American Staffordshire terriers (p < 0.05). The clinical signs of atopic dermatitis and their occurrence are in accordance with the data described in the literature.

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