scholarly journals Assessment of antigenic difference of equine influenza virus strains by challenge study in horses

2016 ◽  
Vol 10 (6) ◽  
pp. 536-539 ◽  
Author(s):  
Takashi Yamanaka ◽  
Manabu Nemoto ◽  
Hiroshi Bannai ◽  
Koji Tsujimura ◽  
Takashi Kondo ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Antigenic Difference ◽  
Equine Influenza Virus ◽  
Equine Influenza ◽  
Challenge Study ◽  
Virus Strains

scholarly journals Assessment of antigenic difference of equine influenza virus by challenge study in horses

2016 ◽  
Vol 39 ◽  
pp. S74-S75
Author(s):  
T. Yamanaka ◽  
H. Bannai ◽  
M. Nemoto ◽  
K. Tsujimura ◽  
T. Kondo ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Antigenic Difference ◽  
Equine Influenza Virus ◽  
Equine Influenza ◽  
Challenge Study

scholarly journals Genetic evolution of equine influenza virus strains (H3N8) isolated in France from 1967 to 2015 and the implications of several potential pathogenic factors

Virology ◽  
2017 ◽  
Vol 505 ◽  
pp. 210-217 ◽  
Author(s):  
Stéphanie Fougerolle ◽  
Loïc Legrand ◽  
Fanny Lecouturier ◽  
Corinne Sailleau ◽  
Romain Paillot ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Genetic Evolution ◽  
Equine Influenza Virus ◽  
Equine Influenza ◽  
Pathogenic Factors ◽  
Virus Strains

scholarly journals Complete Genomic Sequences of H3N8 Equine Influenza Virus Strains Used as Vaccine Strains in Japan

2018 ◽  
Vol 6 (12) ◽  
Author(s):  
Manabu Nemoto ◽  
Takashi Yamanaka ◽  
Hiroshi Bannai ◽  
Koji Tsujimura ◽  
Hiroshi Kokado
Keyword(s):  
Influenza Virus ◽  
Influenza A Virus ◽  
Influenza A ◽  
Animal Health ◽  
Genomic Sequences ◽  
Equine Influenza Virus ◽  
Equine Influenza ◽  
World Organization ◽  
Virus Strains ◽  
Complete Genomic

ABSTRACT We sequenced the eight segments of influenza A virus strains A/equine/Ibaraki/1/2007 and A/equine/Yokohama/aq13/2010, which are strains of the Florida sublineage clades 1 and 2 of the H3N8 subtype equine influenza virus. These strains have been used as vaccine strains in Japan since 2016 in accordance with World Organization for Animal Health (OIE) recommendations.

scholarly journals Complete Genome Sequencing of Two Equine Influenza A(H3N8) Virus Strains Isolated in Kazakhstan

2018 ◽  
Vol 6 (26) ◽  
Author(s):  
Yerbol Burashev ◽  
Vitaliy Strochkov ◽  
Kulyaisan Sultankulova ◽  
Mukhit Orynbayev ◽  
Abylay Sansyzbay ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Genome Sequencing ◽  
Complete Genome ◽  
Influenza A ◽  
Equine Influenza Virus ◽  
Equine Influenza ◽  
Complete Genome Sequencing ◽  
H3n8 Virus ◽  
Virus Strains

Here, we report the complete genome sequencing of strains A/equine/Kostanay/9/2012(H3N8) and A/equine/LKZ/9/2012(H3N8) of the equine influenza virus belonging to Florida sublineage, clade 2. The strains were isolated in 2012 in the northern and southern regions of Kazakhstan, respectively.

scholarly journals Different pattern of haemagglutinin immunoreactivity of equine influenza virus strains isolated in Poland

2015 ◽  
Vol 59 (4) ◽  
pp. 463-466
Author(s):  
Małgorzata Kwaśnik ◽  
Ilona Marcelina Góra ◽  
Wojciech Rożek
Keyword(s):  
Monoclonal Antibody ◽  
Influenza Virus ◽  
Amino Acid ◽  
Point Mutations ◽  
Amino Acid Sequences ◽  
Equine Influenza Virus ◽  
Equine Influenza ◽  
Antigenic Sites ◽  
Virus Strains

Abstract The immunoreactivity of haemagglutinin (HA) polypeptides of equine influenza virus was compared among the strains isolated in Poland, using H3 monoclonal antibody. A stronger signal in immunoblot reaction was observed for A/equi/Pulawy/2008 HA polypeptides compared to A/equi/Pulawy/2006, despite the fact that both strains are phylogenetically closely related and belong to Florida clade 2 of American lineage. The strongest signal, observed in the case of A/equi/Pulawy/2008, seemed to be connected with the presence of G135, I213, E379, and/or V530 instead of R135, M213, G379, and I530 present in A/equi/Pulawy/2006 HA sequence. This implies that point mutations within amino acid sequences of HA polypeptides of equine influenza virus may change their immunoreactivity even when they are not located within five basic antigenic sites.

scholarly journals Antigenic and genetic variations in European and North American equine influenza virus strains (H3N8) isolated from 2006 to 2007

2009 ◽  
Vol 138 (1-2) ◽  
pp. 41-52 ◽  
Author(s):  
Neil A. Bryant ◽  
Adam S. Rash ◽  
Colin A. Russell ◽  
Julie Ross ◽  
Annie Cooke ◽  
...  
Keyword(s):  
Influenza Virus ◽  
North American ◽  
Genetic Variations ◽  
Equine Influenza Virus ◽  
Equine Influenza ◽  
Virus Strains

Protein expression changes in cells inoculated with Equine Influenza Virus: antibody microarray analysis

2013 ◽  
Vol 16 (4) ◽  
pp. 663-669
Author(s):  
W. Rozek ◽  
M. Kwasnik ◽  
J.F. Zmudzinski
Keyword(s):  
Influenza Virus ◽  
Protein Quality ◽  
Biological Properties ◽  
Regulation Of Transcription ◽  
Equine Influenza Virus ◽  
Virus Antibody ◽  
Antibody Microarray ◽  
Equine Influenza ◽  
Microarray Technique ◽  
In Cells

AbstractChanges in the level of cellular proteins in cells inoculated with equine influenza virus H7N7 and H3N8 were studied with microarray technique. H3N8 induced pro-apoptotic proteins while H7N7 induced both pro- as well as anti-apoptotic factors. The higher level of some cytoskeleton components and proteins involved in the protein quality control was recorded. Relatively high number of proteins involved in the regulation of transcription was down-regulated. The pattern of changes observed for H7N7 and H3N8 may reflect differences in the biological properties of both serotypes.

scholarly journals Protection against the New Equine Influenza Virus Florida Clade I Outbreak Strain Provided by a Whole Inactivated Virus Vaccine

Vaccines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 784
Author(s):  
Sylvia Reemers ◽  
Sander van Bommel ◽  
Qi Cao ◽  
David Sutton ◽  
Saskia van de Zande
Keyword(s):  
Influenza Virus ◽  
Virus Vaccine ◽  
Clinical Signs ◽  
Field Strain ◽  
Equine Influenza Virus ◽  
Outbreak Strain ◽  
Virus Shedding ◽  
Equine Influenza ◽  
Vaccine Type ◽  
High Level

Equine influenza virus (EIV) is a major cause of respiratory disease in horses. Vaccination is an effective tool for infection control. Although various EIV vaccines are widely available, major outbreaks occurred in Europe in 2018 involving a new EIV H3N8 FC1 strain. In France, it was reported that both unvaccinated and vaccinated horses were affected despite >80% vaccination coverage and most horses being vaccinated with a vaccine expressing FC1 antigen. This study assessed whether vaccine type, next to antigenic difference between vaccine and field strain, plays a role. Horses were vaccinated with an ISCOMatrix-adjuvanted, whole inactivated virus vaccine (Equilis Prequenza) and experimentally infected with the new FC1 outbreak strain. Serology (HI), clinical signs, and virus shedding were evaluated in vaccinated compared to unvaccinated horses. Results showed a significant reduction in clinical signs and a lack of virus shedding in vaccinated horses compared to unvaccinated controls. From these results, it can be concluded that Equilis Prequenza provides a high level of protection to challenge with the new FC1 outbreak strain. This suggests that, apart from antigenic differences between vaccine and field strain, other aspects of the vaccine may also play an important role in determining field efficacy.

scholarly journals PREVALENCE OF ANTIBODIES AGAINST INFLUENZA VIRUS IN NON-VACCINATED EQUINES FROM THE BRAZILIAN PANTANAL

2014 ◽  
Vol 56 (6) ◽  
pp. 487-492 ◽  
Author(s):  
Lucas Gaíva E Silva ◽  
Alice Mamede Costa Marques Borges ◽  
Eliana Monteforte Cassaro Villalobos ◽  
Maria do Carmo Custodio Souza Hunold Lara ◽  
Elenice Maria Siquetin Cunha ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Equine Infectious Anemia Virus ◽  
Linear Regression Models ◽  
Equine Influenza Virus ◽  
Chi Square ◽  
Equine Influenza ◽  
Hemagglutination Inhibition Test ◽  
Chi Square Test ◽  
Spatial Autoregressive ◽  
Anemia Virus

The prevalence of antibodies against Equine Influenza Virus (EIV) was determined in 529 equines living on ranches in the municipality of Poconé, Pantanal area of Brazil, by means of the hemagglutination inhibition test, using subtype H3N8 as antigen. The distribution and possible association among positive animal and ranches were evaluated by the chi-square test, spatial autoregressive and multiple linear regression models. The prevalence of antibodies against EIV was estimated at 45.2% (95% CI 30.2 - 61.1%) with titers ranging from 20 to 1,280 HAU. Seropositive equines were found on 92.0% of the surveyed ranches. Equine from non-flooded ranches (66.5%) and negativity in equine infectious anemia virus (EIAV) (61.7%) were associated with antibodies against EIV. No spatial correlation was found among the ranches, but the ones located in non-flooded areas were associated with antibodies against EIV. A negative correlation was found between the prevalence of antibodies against EIV and the presence of EIAV positive animals on the ranches. The high prevalence of antibodies against EIV detected in this study suggests that the virus is circulating among the animals, and this statistical analysis indicates that the movement and aggregation of animals are factors associated to the transmission of the virus in the region.

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