Sequence of morphological events during topical application of retinoic acid on the rhino mouse skin

1991 ◽  
Vol 125 (5) ◽  
pp. 419-425 ◽  
Author(s):  
FRANCOISE BERNERD ◽  
M. DEMARCHEZ ◽  
J.-P. ORTONNE ◽  
J. CZERNIELEWSKI
Keyword(s):  
Retinoic Acid ◽  
Topical Application ◽  
Mouse Skin ◽  
Rhino Mouse

Regulation of Cellular Retinoic Acid Binding Protein Expression in Rhino Mouse Skin by All-trans-Retinoic Acid

1995 ◽  
Vol 8 (4) ◽  
pp. 167-172 ◽  
Author(s):  
Gerard J. Gendimenico ◽  
John P. Mallon ◽  
Matthew A. Cromie ◽  
James A. Mezick ◽  
Anders Åström ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Protein Expression ◽  
Binding Protein ◽  
Mouse Skin ◽  
Acid Binding Protein ◽  
Rhino Mouse

scholarly journals Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid

PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0188887 ◽  
Author(s):  
Jamie M. Ahrens ◽  
James D. Jones ◽  
Nirca J. Nieves ◽  
Ann M. Mitzey ◽  
Hector F. DeLuca ◽  
...  
Keyword(s):  
Gene Expression ◽  
Vitamin D ◽  
Retinoic Acid ◽  
Growth Factor ◽  
Mouse Skin ◽  
Factor Gene ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid ◽  
Growth Factor Gene ◽  
Rhino Mouse

DNA Ploidy Changes in Rhino Mouse Skin Induced by All-Trans Retinoic Acid and Retinol

1997 ◽  
Vol 10 (3) ◽  
pp. 135-143 ◽  
Author(s):  
Salvador González ◽  
María Victoría Alcaraz ◽  
Florentina Díaz ◽  
Thomas J. Flotte ◽  
Ignacio Pérez de Vargas ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Dna Ploidy ◽  
Mouse Skin ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid ◽  
Ploidy Changes ◽  
Rhino Mouse

Role of Retinoic Acid Receptor Gamma in the Rhino Mouse and Rabbit Irritation Models of Retinoid Activity

1995 ◽  
Vol 8 (6) ◽  
pp. 292-299 ◽  
Author(s):  
Peter R. Reczek ◽  
Jacek Ostrowski ◽  
Kuo-Long Yu ◽  
Simon Chen ◽  
Laura Hammer ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Retinoic Acid Receptor ◽  
Acid Receptor ◽  
Rhino Mouse

The early changes in mouse skin following topical application of a range of middle distillate oil products

1993 ◽  
Vol 13 (4) ◽  
pp. 247-257 ◽  
Author(s):  
A. J. Ingram ◽  
D. J. King ◽  
P. Grasso ◽  
M. Sharratt
Keyword(s):  
Topical Application ◽  
Mouse Skin ◽  
Oil Products ◽  
Middle Distillate

Estrogen regulates the expression of retinoic acid synthesis enzymes and binding proteins in mouse skin

2021 ◽  
Author(s):  
Helen B. Everts ◽  
Kathleen A. Silva ◽  
Adriana N. Schmidt ◽  
Susan Opalenikx ◽  
F. Jason Duncan ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Binding Proteins ◽  
Mouse Skin ◽  
Acid Synthesis

scholarly journals Topical Application of Cinnamaldehyde Promotes Faster Healing of Skin Wounds Infected with Pseudomonas aeruginosa

Molecules ◽  
2019 ◽  
Vol 24 (8) ◽  
pp. 1627 ◽  
Author(s):  
Thiago A.F. Ferro ◽  
Eliene B. Souza ◽  
Mariela A.M. Suarez ◽  
João F.S. Rodrigues ◽  
Domingos M.S. Pereira ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Topical Application ◽  
Transient Receptor Potential ◽  
Bacterial Load ◽  
Unmet Need ◽  
Antimicrobial Properties ◽  
Mouse Skin ◽  
Interleukin 17 ◽  
Skin Wounds ◽  
Infected Skin

Wound healing can be delayed following colonization and infection with the common bacterium Pseudomonas aeruginosa. While multiple therapies are used for their treatment, these are ineffective, expensive, and labour-intensive. Thus, there is an enormous unmet need for the treatment of infected wounds. Cinnamaldehyde, the major component of cinnamon oil, is well known for its antimicrobial properties. Herein, we investigated the effects of sub-inhibitory concentrations of cinnamaldehyde in the virulence of P. aeruginosa. We also assessed its healing potential in P. aeruginosa-infected mouse skin wounds and the mechanisms involved in this response. Sub-inhibitory concentrations of cinnamaldehyde reduced P. aeruginosa metabolic rate and its ability to form biofilm and to cause haemolysis. Daily topical application of cinnamaldehyde on P. aeruginosa-infected skin wounds reduced tissue bacterial load and promoted faster healing. Lower interleukin-17 (IL-17), vascular endothelial growth factor (VEGF) and nitric oxide levels were detected in cinnamaldehyde-treated wound samples. Blockage of transient receptor potential ankyrin 1, the pharmacological target of cinnamaldehyde, abrogated its healing activity and partially reversed the inhibitory actions of this compound on VEGF and IL-17 generation. We suggest that topical application of sub-inhibitory concentrations of cinnamaldehyde may represent an interesting approach to improve the healing of P. aeruginosa-infected skin wounds.

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