Relationship of serum interleukin-7 concentration and the coagulation state in children with nephrotic syndrome

2005 ◽  
Vol 47 (4) ◽  
pp. 424-429 ◽  
Author(s):  
Anna Wasilewska ◽  
Walentyna M Zoch-Zwierz ◽  
Barbara Tomaszewska ◽  
Beata Zelazowska
Keyword(s):  
Nephrotic Syndrome ◽  
Interleukin 7 ◽  
Relationship Of

Elevated serum interleukin-7 level in idiopathic steroid-sensitive nephrotic syndrome

2011 ◽  
Vol 53 (6) ◽  
pp. 906-909 ◽  
Author(s):  
Takahiro Kanai ◽  
Hirohiko Shiraishi ◽  
Takanori Yamagata ◽  
Takane Ito ◽  
Jun Odaka ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Elevated Serum ◽  
Interleukin 7 ◽  
Steroid Sensitive Nephrotic Syndrome ◽  
Steroid Sensitive

scholarly journals Influence of prednisone therapy on physical development of children with nephrotic syndrome

2019 ◽  
Vol 23 (5) ◽  
pp. 88-95 ◽  
Author(s):  
T. L. Nastausheva ◽  
E. E. Boeva ◽  
T. G. Zvyagina ◽  
E. N. Kulakova ◽  
N. S. Nastausheva ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Weight ◽  
Nephrotic Syndrome ◽  
Body Mass ◽  
Cumulative Dose ◽  
Physical Development ◽  
The Body ◽  
Prednisone Therapy ◽  
Steroid Sensitive ◽  
Relationship Of

THE AIM: to compare the parameters of physical development (PD) in children with idiopathic nephrotic syndrome (INS), depending on the treatment with prednisone.PATIENTS AND METHODS. The effect of treatment with prednisone on PD was analyzed in 60 children with INS aged from 2 to 17 years. The children were divided into 2 groups: 30 children who did not receive prednisone, and 30 children who received it during the last 6 months before the study (1st and 2nd group, respectively). The groups compared the anamnestic parameters and the risk factors of children in terms of length, weight, and body mass index.RESULTS. When comparing the characteristics of the risk factors of children of the above 2 groups, differences in body mass and BMI were established. In children who received prednisone for the last 6 months, body weight and BMI were significantly exceeded compared to WHO standards and similar patients who did not receive prednisone for the last 6 months. We have established a reliable association of the Z-BMI criterion with the cumulative dose of prednisone in the last 6 months: r = 0.49, p <0.05. At the same time, no reliable association of body weight with a cumulative dose of prednisone, which the child received before 6 months, has been identified. When analyzing the effectiveness of different doses of prednisone therapy for stopping relapses in children with steroid-sensitive INS, it was found that the onset and duration of remission did not significantly differ when taking standard (60mg/m2/day or 2 mg/kg/day) and half as much (1mg/kg/day) doses of prednisone.CONCLUSION. The relationship of the body mass of children with INS and the cumulative dose of prednisone in the last 6 months has been established. When treating a recurrent steroid-sensitive non-relapsing INS, a decrease in the daily dose of prednisone from 2 mg/kg/day to 1 mg/kg/day is possible in adolescents who are afraid of steroid obesity or who have had severe complications during previous courses of prednisone therapy.

scholarly journals Identification of a Common Developmental Pathway for Thymic Natural Killer Cells and Dendritic Cells

Blood ◽  
1998 ◽  
Vol 91 (8) ◽  
pp. 2760-2771 ◽  
Author(s):  
Carlos Márquez ◽  
César Trigueros ◽  
Jaime M. Franco ◽  
Almudena R. Ramiro ◽  
Yolanda R. Carrasco ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Nk Cells ◽  
Natural Killer ◽  
Nk Cell ◽  
Surface Expression ◽  
Current Data ◽  
Small Subset ◽  
Interleukin 7 ◽  
Macrophage Colony ◽  
Relationship Of

Current data support the notion that the thymus is seeded by a yet uncommitted progenitor cell able to generate T cells, B cells, natural killer (NK) cells, and dendritic cells (DCs). We assess in this report the developmental relationship of DCs and NK cells derived from a small subset of CD34+ human postnatal thymocytes that, like the earliest precursors in the fetal thymus, display low CD33 surface expression. Culture of these isolated CD34+CD33lo thymic progenitors with a mixture of cytokines, including interleukin-7 (IL-7), IL-1α, IL-6, granulocyte-macrophage colony-stimulating factor, and stem cell factor, results in predominant generation of DCs. However, the addition of IL-2 to the cytokine mixture leads to the simultaneous development of DCs and NK cells. Both developmental pathways progress through a transient population of CD34+CD44brightCD5lo/−CD33+ large-sized cells, distinct from small-sized T-lineage precursors, that contain bipotential NK/DC progenitors. These data provide evidence of linked pathways of NK cell and DC development from intrathymic precursors and suggest that NK cells and DCs branch off the T lineage through a common intermediate progenitor.

scholarly journals RELATIONSHIP OF XEROSIS CUTIS WITH PROTEINURIA DEGREES IN CHILDREN WITH NEPHROTIC SYNDROME AT THE HAJI ADAM MALIK HOSPITAL

2020 ◽  
Vol 7 (8) ◽  
pp. 23-27
Keyword(s):  
Nephrotic Syndrome ◽  
Skin Surface ◽  
Skin Layer ◽  
Research Subjects ◽  
Dipstick Test ◽  
Cross Sectional ◽  
Urine Dipstick Test ◽  
Age Range ◽  
Relationship Of ◽  
The Relationship

Introduction: xerosis cutis is a disorder of the skin surface due to reduced fluid or oil content in the skin that moisture on the surface of the skin layer decreases. Proteinuria is a risk factor for the progression of nephrotic syndrome. Nephrotic syndrome if there is proteinuria (≥40 mg / m2 / hour or protein / creatinine ratio ≥ 200 mg / mL or protein + 3 on urine dipstick test), hypoalbuminemia (<25 g / L) and edema. Objective: To determine the relationship between xerosis cutis and the degree of proteinuria in children with nephrotic syndrome. Subject and Method: This is is a cross-sectional analytic study, involving 50 subject xerosis cutis with nephrotic syndrome patients. Kruskal Wallis test is used to determine the relationship xerosis cutis with proteinuria degree in children with nephrotic syndrome. This study has been approved by the Health Research Ethics Commission of the Faculty of Medicine, Universitas Sumatera Utara/ H. Adam Malik General Hospital Medan. Result: Based on the characteristics of 50 research subjects, the age of all research subjects has a median value of 8 (3-16) years with the most age range at the age of 6-10 years, as many as 26 subjects (52%), male subjects as many as 34 subjects (68 %) and women as many as 16 subjects (32%). The duration of nephrotic syndrome has a median value of 2 (1-7) years. There was a significant skin dryness relationship based on the degree of proteinuria (p = 0.002). Thus it can be concluded that the higher the degree of proteinuria, the higher the level of dryness of the skin and the greater the degree of proteinuria in children with nephrotic syndrome, then indirectly describe the more protein that is wasted through urine. Conclusion: There is a significant xerosis cutis relationship based on the degree of proteinuria (p= 0,002).

scholarly journals Frequency and relationship of ABO blood groups in patients with nephrotic syndrome

2021 ◽  
Author(s):  
İdris Oruç ◽  
Hıdır Sarı ◽  
Songül Araç ◽  
Eren Eynel ◽  
Zafer Pekkolay ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Relationship Of

The relationship of the scleractinian corals to the rugose corals

Paleobiology ◽  
1980 ◽  
Vol 6 (02) ◽  
pp. 146-160 ◽  
Author(s):  
William A. Oliver
Keyword(s):  
Critical Points ◽  
Scleractinian Corals ◽  
Convincing Evidence ◽  
Early Triassic ◽  
Rugose Corals ◽  
History Of ◽  
The Subject ◽  
Relationship Of ◽  
The Relationship ◽  
Biologic Factors

The Mesozoic-Cenozoic coral Order Scleractinia has been suggested to have originated or evolved (1) by direct descent from the Paleozoic Order Rugosa or (2) by the development of a skeleton in members of one of the anemone groups that probably have existed throughout Phanerozoic time. In spite of much work on the subject, advocates of the direct descent hypothesis have failed to find convincing evidence of this relationship. Critical points are:(1) Rugosan septal insertion is serial; Scleractinian insertion is cyclic; no intermediate stages have been demonstrated. Apparent intermediates are Scleractinia having bilateral cyclic insertion or teratological Rugosa.(2) There is convincing evidence that the skeletons of many Rugosa were calcitic and none are known to be or to have been aragonitic. In contrast, the skeletons of all living Scleractinia are aragonitic and there is evidence that fossil Scleractinia were aragonitic also. The mineralogic difference is almost certainly due to intrinsic biologic factors.(3) No early Triassic corals of either group are known. This fact is not compelling (by itself) but is important in connection with points 1 and 2, because, given direct descent, both changes took place during this only stage in the history of the two groups in which there are no known corals.

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