scholarly journals Relationship of proteinuria severity with Xerosis Cutis in children with Nephrotic Syndrome at the Haji Adam Malik Hospital

2020 ◽  
Vol 9 (3) ◽  
pp. 836
Author(s):  
Ami Utamiati ◽  
Sri Wahyuni Purnama ◽  
Irma D Roesyanto
2005 ◽  
Vol 47 (4) ◽  
pp. 424-429 ◽  
Author(s):  
Anna Wasilewska ◽  
Walentyna M Zoch-Zwierz ◽  
Barbara Tomaszewska ◽  
Beata Zelazowska

2019 ◽  
Vol 23 (5) ◽  
pp. 88-95 ◽  
Author(s):  
T. L. Nastausheva ◽  
E. E. Boeva ◽  
T. G. Zvyagina ◽  
E. N. Kulakova ◽  
N. S. Nastausheva ◽  
...  

THE AIM: to compare the parameters of physical development (PD) in children with idiopathic nephrotic syndrome (INS), depending on the treatment with prednisone.PATIENTS AND METHODS. The effect of treatment with prednisone on PD was analyzed in 60 children with INS aged from 2 to 17 years. The children were divided into 2 groups: 30 children who did not receive prednisone, and 30 children who received it during the last 6 months before the study (1st and 2nd group, respectively). The groups compared the anamnestic parameters and the risk factors of children in terms of length, weight, and body mass index.RESULTS. When comparing the characteristics of the risk factors of children of the above 2 groups, differences in body mass and BMI were established. In children who received prednisone for the last 6 months, body weight and BMI were significantly exceeded compared to WHO standards and similar patients who did not receive prednisone for the last 6 months. We have established a reliable association of the Z-BMI criterion with the cumulative dose of prednisone in the last 6 months: r = 0.49, p <0.05. At the same time, no reliable association of body weight with a cumulative dose of prednisone, which the child received before 6 months, has been identified. When analyzing the effectiveness of different doses of prednisone therapy for stopping relapses in children with steroid-sensitive INS, it was found that the onset and duration of remission did not significantly differ when taking standard (60mg/m2/day or 2 mg/kg/day) and half as much (1mg/kg/day) doses of prednisone.CONCLUSION. The relationship of the body mass of children with INS and the cumulative dose of prednisone in the last 6 months has been established. When treating a recurrent steroid-sensitive non-relapsing INS, a decrease in the daily dose of prednisone from 2 mg/kg/day to 1 mg/kg/day is possible in adolescents who are afraid of steroid obesity or who have had severe complications during previous courses of prednisone therapy.


Introduction: xerosis cutis is a disorder of the skin surface due to reduced fluid or oil content in the skin that moisture on the surface of the skin layer decreases. Proteinuria is a risk factor for the progression of nephrotic syndrome. Nephrotic syndrome if there is proteinuria (≥40 mg / m2 / hour or protein / creatinine ratio ≥ 200 mg / mL or protein + 3 on urine dipstick test), hypoalbuminemia (<25 g / L) and edema. Objective: To determine the relationship between xerosis cutis and the degree of proteinuria in children with nephrotic syndrome. Subject and Method: This is is a cross-sectional analytic study, involving 50 subject xerosis cutis with nephrotic syndrome patients. Kruskal Wallis test is used to determine the relationship xerosis cutis with proteinuria degree in children with nephrotic syndrome. This study has been approved by the Health Research Ethics Commission of the Faculty of Medicine, Universitas Sumatera Utara/ H. Adam Malik General Hospital Medan. Result: Based on the characteristics of 50 research subjects, the age of all research subjects has a median value of 8 (3-16) years with the most age range at the age of 6-10 years, as many as 26 subjects (52%), male subjects as many as 34 subjects (68 %) and women as many as 16 subjects (32%). The duration of nephrotic syndrome has a median value of 2 (1-7) years. There was a significant skin dryness relationship based on the degree of proteinuria (p = 0.002). Thus it can be concluded that the higher the degree of proteinuria, the higher the level of dryness of the skin and the greater the degree of proteinuria in children with nephrotic syndrome, then indirectly describe the more protein that is wasted through urine. Conclusion: There is a significant xerosis cutis relationship based on the degree of proteinuria (p= 0,002).


Author(s):  
İdris Oruç ◽  
Hıdır Sarı ◽  
Songül Araç ◽  
Eren Eynel ◽  
Zafer Pekkolay ◽  
...  

Paleobiology ◽  
1980 ◽  
Vol 6 (02) ◽  
pp. 146-160 ◽  
Author(s):  
William A. Oliver

The Mesozoic-Cenozoic coral Order Scleractinia has been suggested to have originated or evolved (1) by direct descent from the Paleozoic Order Rugosa or (2) by the development of a skeleton in members of one of the anemone groups that probably have existed throughout Phanerozoic time. In spite of much work on the subject, advocates of the direct descent hypothesis have failed to find convincing evidence of this relationship. Critical points are:(1) Rugosan septal insertion is serial; Scleractinian insertion is cyclic; no intermediate stages have been demonstrated. Apparent intermediates are Scleractinia having bilateral cyclic insertion or teratological Rugosa.(2) There is convincing evidence that the skeletons of many Rugosa were calcitic and none are known to be or to have been aragonitic. In contrast, the skeletons of all living Scleractinia are aragonitic and there is evidence that fossil Scleractinia were aragonitic also. The mineralogic difference is almost certainly due to intrinsic biologic factors.(3) No early Triassic corals of either group are known. This fact is not compelling (by itself) but is important in connection with points 1 and 2, because, given direct descent, both changes took place during this only stage in the history of the two groups in which there are no known corals.


Author(s):  
D. F. Blake ◽  
L. F. Allard ◽  
D. R. Peacor

Echinodermata is a phylum of marine invertebrates which has been extant since Cambrian time (c.a. 500 m.y. before the present). Modern examples of echinoderms include sea urchins, sea stars, and sea lilies (crinoids). The endoskeletons of echinoderms are composed of plates or ossicles (Fig. 1) which are with few exceptions, porous, single crystals of high-magnesian calcite. Despite their single crystal nature, fracture surfaces do not exhibit the near-perfect {10.4} cleavage characteristic of inorganic calcite. This paradoxical mix of biogenic and inorganic features has prompted much recent work on echinoderm skeletal crystallography. Furthermore, fossil echinoderm hard parts comprise a volumetrically significant portion of some marine limestones sequences. The ultrastructural and microchemical characterization of modern skeletal material should lend insight into: 1). The nature of the biogenic processes involved, for example, the relationship of Mg heterogeneity to morphological and structural features in modern echinoderm material, and 2). The nature of the diagenetic changes undergone by their ancient, fossilized counterparts. In this study, high resolution TEM (HRTEM), high voltage TEM (HVTEM), and STEM microanalysis are used to characterize tha ultrastructural and microchemical composition of skeletal elements of the modern crinoid Neocrinus blakei.


Author(s):  
Leon Dmochowski

Electron microscopy has proved to be an invaluable discipline in studies on the relationship of viruses to the origin of leukemia, sarcoma, and other types of tumors in animals and man. The successful cell-free transmission of leukemia and sarcoma in mice, rats, hamsters, and cats, interpreted as due to a virus or viruses, was proved to be due to a virus on the basis of electron microscope studies. These studies demonstrated that all the types of neoplasia in animals of the species examined are produced by a virus of certain characteristic morphological properties similar, if not identical, in the mode of development in all types of neoplasia in animals, as shown in Fig. 1.


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