Foods and beverages in relation to urothelial cancer: Case-control study in Japan

Background Breast cancer has a major disease burden in the female population, and it is a highly genome-associated human disease. However, in genetic studies of complex diseases, modern geneticists face challenges in detecting interactions among loci. Objective This study aimed to investigate whether variations of single-nucleotide polymorphisms (SNPs) are associated with histopathological tumor characteristics in breast cancer patients. Methods A hybrid Taguchi-genetic algorithm (HTGA) was proposed to identify the high-order SNP barcodes in a breast cancer case-control study. A Taguchi method was used to enhance a genetic algorithm (GA) for identifying high-order SNP barcodes. The Taguchi method was integrated into the GA after the crossover operations in order to optimize the generated offspring systematically for enhancing the GA search ability. Results The proposed HTGA effectively converged to a promising region within the problem space and provided excellent SNP barcode identification. Regression analysis was used to validate the association between breast cancer and the identified high-order SNP barcodes. The maximum OR was less than 1 (range 0.870-0.755) for two- to seven-order SNP barcodes. Conclusions We systematically evaluated the interaction effects of 26 SNPs within growth factor–related genes for breast carcinogenesis pathways. The HTGA could successfully identify relevant high-order SNP barcodes by evaluating the differences between cases and controls. The validation results showed that the HTGA can provide better fitness values as compared with other methods for the identification of high-order SNP barcodes using breast cancer case-control data sets.

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Survey on the association between eating habits, anthropometry and colorectal cancer: Case-control study in a population of eastern Algeria 2016-2017

Nutrition & Santé ◽

10.30952/ns.6.2.4 ◽

2017 ◽

Vol 06 (02) ◽

pp. 74-82

Author(s):

Samira NEGRICHI ◽

◽

Salima TALEB ◽

Sabiha BOUZBID ◽

Keyword(s):

Colorectal Cancer ◽

Case Control Study ◽

Eating Habits ◽

Case Control ◽

Cancer Case ◽

Colorectal Cancer Case ◽

Eastern Algeria ◽

Control Study

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Risk factors associated with the development of gastric cancer — case-control study

Revista da Associação Médica Brasileira ◽

10.1590/1806-9282.64.07.611 ◽

2018 ◽

Vol 64 (7) ◽

pp. 611-619 ◽

Cited By ~ 8

Author(s):

Marcus Fernando Kodama Pertille Ramos ◽

Ulysses Ribeiro Júnior ◽

Juliana Kodaira Yukari Viscondi ◽

Bruno Zilberstein ◽

Ivan Cecconello ◽

...

Keyword(s):

Risk Factors ◽

Gastric Cancer ◽

Case Control Study ◽

Case Control ◽

Cancer Case ◽

Gastric Cancer Case ◽

Factors Associated ◽

Control Study ◽

Development Of Gastric Cancer

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High resolution human leukocyte antigen (HLA) class I and class II allele typing in Mexican mestizo women with sporadic breast cancer: case-control study

BMC Cancer ◽

10.1186/1471-2407-9-48 ◽

2009 ◽

Vol 9 (1) ◽

Cited By ~ 10

Author(s):

David Cantú de León ◽

Delia Pérez-Montiel ◽

Verónica Villavicencio ◽

Alejandro García Carranca ◽

Alejandro Mohar Betancourt ◽

...

Keyword(s):

Sporadic Breast Cancer ◽

Case Control Study ◽

Human Leukocyte ◽

Breast Cancer Case ◽

Hla Class I ◽

Case Control ◽

Cancer Case ◽

Mexican Mestizo ◽

Leukocyte Antigen ◽

Control Study

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Bladder cancer and occupational exposure to metalworking fluid mist: a counter-matched case–control study in French steel-producing factories

Occupational and Environmental Medicine ◽

10.1136/oemed-2017-104666 ◽

2018 ◽

Vol 75 (5) ◽

pp. 328-336 ◽

Cited By ~ 5

Author(s):

Régis Colin ◽

Michel Grzebyk ◽

Pascal Wild ◽

Guy Hédelin ◽

Ève Bourgkard

Keyword(s):

Bladder Cancer ◽

Occupational Exposure ◽

Case Control Study ◽

Occupational Exposures ◽

Case Control ◽

Metalworking Fluids ◽

Cumulative Exposure ◽

Cancer Case ◽

Increased Risk ◽

Control Study

ObjectivesTo assess the relationship between occupational exposure to metalworking fluids (MWFs) in the steel-producing industry and bladder cancer incidence.MethodsA nested case–control study on bladder cancer was set up in a cohort of workers from six French steel-producing factories. Three controls were randomly selected for each incident bladder cancer case diagnosed from 2006 to 2012. Controls were matched to cases on age at diagnosis and counter-matched on a surrogate measure of exposure to MWFs derived from a job-exposure matrix. Cases (n=84) and controls (n=251) were face-to-face interviewed. Experts assessed occupational exposure to MWFs (straight, soluble and synthetic) using questionnaires and reports from factory visits. Occupational exposures were based on three metrics: duration, frequency-weighted duration and cumulative exposure index. Conditional multiple logistic regressions were used to determine ORs and 95% CIs, taking non-occupational and occupational exposure into account.ResultsIn the 25 years before diagnosis, ORs increased significantly with duration of exposure to straight MWFs (OR=1.13 (1.02–1.25)) and increased with frequency-weighted duration of exposure to straight MWFs (OR=1.44 (0.97–2.14)). These results remained valid after adjusting for duration of smoking, average number of cigarettes smoked per day, time since smoking cessation and exposure to polycyclic aromatic hydrocarbons (PAHs). ORs also increased with soluble MWFs but not significantly. No significant association was found with older exposures to MWFs or with exposure to synthetic MWFs.ConclusionThe increased risk of bladder cancer observed among workers exposed to straight MWFs and to a lesser extent to soluble MWFs may be explained by the presence of carcinogens (such as PAH) in mineral oils component of straight and soluble oils. Prevention therefore remains necessary in sectors using MWFs.

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