Electrophysiological correlates of response inhibition in children and adolescents with ADHD: Influence of gender, age, and previous treatment history

2007 ◽  
Vol 44 (6) ◽  
pp. 936-948 ◽  
Author(s):  
Mario Liotti ◽  
Steven R. Pliszka ◽  
Ricardo Perez ◽  
Brian Luus ◽  
David Glahn ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Response Inhibition ◽  
Previous Treatment ◽  
Treatment History

Gene mutation and drug resistance of M. tuberculosis in the patients followed up in the city of Moscow

2020 ◽  
Vol 97 (12) ◽  
pp. 34-44
Author(s):  
M. A. Krasnova ◽  
E. M. Belilovsky ◽  
S. E. Borisov ◽  
A. A. Khakhalina ◽  
Yu. D. Mikhaylova ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Statistical Significance ◽  
Molecular Genetic ◽  
Previous Treatment ◽  
Repeated Treatment ◽  
Phenotypic Resistance ◽  
Therapy Regimen ◽  
Treatment History ◽  
History Of ◽  
Relationship Of

The article describes a retrospective study of the results of microbiological and molecular genetic tests of 685 M. tuberculosis cultures isolated from 685 adult tuberculosis patients registered for dispensary follow-up in Moscow in 2014.The following was identified during the study: phenotypic drug resistance (FDR) of MTB to rifampicin, isoniazid, fluoroquinolones, kanamycin, amikacin, and capreomycin in groups of patients with different treatment history; the frequency of FDR to the above anti-tuberculosis drugs in strains with mutations being drug resistance markers; the frequency of various mutations in case of FDR of mycobacteria in the patients from different groups; the relationship of FDR or the presence of a particular mutation with various characteristics of the patients and their treatment history.The history of previous treatment was determined as statistical significance to provide the greatest influence on the spread of drug resistant MTB: patients undergoing repeated treatment had FDR more often and also a much more pronounced variety of mutations being markers of FDR to certain anti-tuberculosis drugs.The results of the study showed that the detection of genetic mutations in MBT associated with FDR was a reliable tool for predicting phenotypic resistance and should be used as the main method for selecting anti-tuberculosis drugs when compiling the etiotropic therapy regimen.

scholarly journals Treatment of children and adolescents with hemangioma using propranolol: preliminary results from a retrospective study

2014 ◽  
Vol 132 (1) ◽  
pp. 48-54 ◽  
Author(s):  
Juliana Costa Albuquerque ◽  
Rosane Aline Magalhaes ◽  
Jamille Araujo Felix ◽  
Maria Vilani Rodrigues Bastos ◽  
Juvenia Bezerra Fontenele ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Children And Adolescents ◽  
Previous Treatment ◽  
Capillary Hemangioma ◽  
Response To Treatment ◽  
Vascular Tumors ◽  
Lesion Volume ◽  
Chi Square ◽  
One Year ◽  
Almost All

CONTEXT AND OBJECTIVE: Hemangiomas are the commonest vascular tumors during childhood. In 2008, the effect of propranolol for treating capillary hemangiomas was demonstrated. Other similar results followed, showing that it rapidly reduces lesion volume. The objective here was to evaluate children and adolescents with hemangiomas that were treated with propranolol. DESIGN AND SETTING: Retrospective study, conducted in a children's hospital. METHODS : Patients aged 0-19 years with or without previous treatment, who were treated between January 2009 and December 2010, were included. The response was assessed by comparing the lesion appearance between the start of treatment and the last consultation. We considered partial or complete responses as the response to treatment. RESULTS : Sixty-nine patients with a median follow-up of 11 months (mean age: 31 months) were included. Of these, 58 patients were recently diagnosed and 11 had had previous treatment. A response (partial or complete) was seen in 60 patients (87%). Among the capillary hemangioma cases, responses were seen in 50 out of 53 (94%), while in other lesion types, it was 10 out of 16 (63%) (P = 0.3; chi-square). Responses in patients less than one year of age were seen in 37 out of 38 (97%), whereas in those over one year of age, in 23 out of 31 (74%) (P = 0.4; chi-square). Side effects were uncommon and mild. CONCLUSIONS: Propranolol seemed to be effective for treatment of hemangiomas in children and adolescents, and not just in the proliferative stage, with responses in almost all the patients.

scholarly journals Asymmetric developmental change regarding the effect of reward and punishment on response inhibition

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Mami Miyasaka ◽  
Michio Nomura
Keyword(s):  
Children And Adolescents ◽  
Inhibitory Control ◽  
Response Inhibition ◽  
Developmental Change ◽  
Reaction Times ◽  
Present Condition ◽  
Feedback Type ◽  
Absent Condition ◽  
Gains And Losses ◽  
Reward And Punishment

Abstract Reward and punishment influence inhibitory performance, but developmental changes in these effects are not well understood. Our aim was to understand the effects of potential reward gains and losses (as indices of reward and punishment) on response inhibition among children and adolescents. We conducted financial and non-financial go/no-go tasks with 40 boys (8- to 15-year-olds). Participants gained or lost money depending on their performance on the financial task, and score rankings were compared to participants on the non-financial task. We found that adolescents’ inhibitory control, as reflected in their reaction times when they made inhibitory errors, was lower in the reward-present condition than in the reward-absent condition, although accuracy was higher when the reward was available for all participants. Additionally, inhibitory control, specifically among adolescents, was higher for financial feedback than for non-financial feedback. These results suggest that the effects of reward and feedback type on motor impulsivity differ as a function of developmental stage. We discuss the theoretical implications of the present findings in terms of the interaction between emotional feedback and response inhibition among children and adolescents.

Differential effects of social and non-social reward on response inhibition in children and adolescents

2009 ◽  
Vol 12 (4) ◽  
pp. 614-625 ◽  
Author(s):  
Gregor Kohls ◽  
Judith Peltzer ◽  
Beate Herpertz-Dahlmann ◽  
Kerstin Konrad
Keyword(s):  
Children And Adolescents ◽  
Response Inhibition ◽  
Social Reward ◽  
Differential Effects

Effects of waiting time on appointment attendance with clinical psychologists and length of treatment

1997 ◽  
Vol 14 (2) ◽  
pp. 49-54 ◽  
Author(s):  
Konstantinos S Loumidis ◽  
Julia M Shropshire
Keyword(s):  
Waiting Time ◽  
Clinical Psychology ◽  
Psychological Treatment ◽  
Previous Treatment ◽  
Young Age ◽  
Clinical Psychologists ◽  
Appointment Attendance ◽  
Treatment History ◽  
Complex Problems ◽  
C Complex

AbstractObjective: With the increasing demand for clinical psychology services and the existing shortage of clinical psychologists, it is theoretically and clinically important to identify variables associated with non-attendance for clinical psychology appointments. The study reported here attempted to: (a) examine the effect of waiting time for an appointment on non-attendance to clinical psychology services; (b) investigate variables associated with prolonged waiting time; (c) explore the nature of the relationship between waiting time and length of psychological treatment.Method: The records of 49 3 patients offered an appointment to attend a clinical psychology service over a period of 24 months were analysed. Subsequently information on sex, age, type of referring problem, previous treatment history, treatment venue and waiting time for appointment, was collected and statistically analysed.Results: Non-attendance was significantly related to prolonged waiting time and young age. Controlling for the effects of waiting time and age, patients with complex problems and new patients wh o had never sought psychological treatment in the past were less likely to attend. Length of waiting time was higher in groups with previous treatment history, patients seen at a hospital based department, and patients with complex problems and anxiety disorders. Finally, length of psychological treatment (total number of sessions required) was not affected by prolonged waiting time.Conclusion: Non-attendance for clinical psychology appointments was associated with (a) young age, (b) prolonged waiting time (over six months), (c) complex psychological problems, and (d) new patients. The limitations and clinical implications of these findings are critically discussed.

Effects of Switching to Once-Daily Modified-Release Methylphenidate From Previous Treatment With Other Psychostimulants in Children and Adolescents With ADHD

2014 ◽  
Vol 34 (1) ◽  
pp. 168-171 ◽  
Author(s):  
Jan Frölich ◽  
Dieter Breuer ◽  
Anja Görtz-Dorten ◽  
Frauke Amonn ◽  
Roland Fischer ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Previous Treatment ◽  
Modified Release ◽  
Once Daily

scholarly journals Analysis of the frequency of pediatric cancer in the Western Amazon (Brazil)

2020 ◽  
Vol 8 (5) ◽  
pp. 479-497
Author(s):  
Carlos Alberto Paraguassu-Chaves ◽  
Allan Kardec Duailibe Barros Filho ◽  
Carlos de Andrade Macieira ◽  
Fabrício Moraes de Almeida ◽  
Lenita Rodrigues Moreira Dantas ◽  
...  
Keyword(s):  
Public Health ◽  
Health System ◽  
Children And Adolescents ◽  
Pediatric Cancer ◽  
Public Health System ◽  
Public Health Problem ◽  
Previous Treatment ◽  
Disease Diagnosis ◽  
Histological Types ◽  
Cancer In Children

Objective: Analyzes the frequency of cancer in children and adolescents in the State of Rondônia / Western Amazon (Brazil), attended by public health services. Method: This is a descriptive, quantitative and cross-sectional study. We used an instrument developed by Paraguassú-Chaves et al [24], semi-structured, containing a series of variables, such as sex, age, histological types, types of cancer by location of the primary tumor, lymphomas, leukemias, clinical stage of the disease, diagnosis and previous treatment, among others. We asked the Research Ethics Committee to waive the Free and Informed Consent Term, because the study did not require patient intervention or collection of biological material and there was no possibility of constraints for patients and their families. Results: From 122 cases, 56 (45.9%) were female and 66 (55.1%) were male. Regarding the distribution of patients according to the age group, 38 (31.1%) were younger than 4 years, 21 (17.2%), 5 to 9 years, 24 (19.7%) from 10 to 14 and 39 (32.0%) from 15 to 19. The most frequent histological types by gender were myeloproliferative leukemias and myelodysplastic diseases with 39.31% of new cases, reticuloendothelial lymphomas and neoplasms 11.96%, carcinomas and other epithelial neoplasms 11.96% of cases and CNS and several cranial intra-neoplasms and intraspinal with 11.11% of new cases. Leukemia in the hematopoietic and reticuloendothelial system (C42) is the most frequent cancer in children and adolescents, with 46.2% of cancers in the studied period. 20.5% of the cases do not know the stage of the cancer and 79.5% of the patients do not have information about the stage of the disease. 99.38% of pediatric cancer cases are referred by the single public health system - SUS and only 0.11% non-SUS or private health system. 47.6% of children and adolescents who arrive at the cancer clinic of the public health system have no diagnosis or previous treatment. Conclusions: he results presented are similar to the studies carried out in Rondônia, Brazil and other countries and are in agreement with the studies by Paraguassú-Chaves et al [24], Paraguassú-Chaves et al [27] and Paraguassú-Chaves et al [28].Considering some parameters and indicators, it can be concluded that childhood cancer in Rondônia is a public health problem.

scholarly journals A Review of Executive Functions in Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder

2018 ◽  
Vol 8 (2) ◽  
pp. 107
Author(s):  
Carmen Berenguer ◽  
Belen Rosello ◽  
Geraldine Leader
Keyword(s):  
Autism Spectrum Disorder ◽  
Attention Deficit Hyperactivity Disorder ◽  
Working Memory ◽  
Executive Functions ◽  
Children And Adolescents ◽  
Response Inhibition ◽  
Attention Deficit ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Hyperactivity Disorder

Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are two of the most common childhood-onset neurodevelopmental disorders. Literature has shown different patterns of deficits in executive functioning in children with ASD and ADHD. To date few studies have examined executive functions in both ASD and ADHD and with mixed results.The current study provides the first systematic review to explore distinct executive function components (attention problems, response inhibition, working memory, planning and flexibility) that underlie the specific deficits seen in children and adolescents with both ASD and ADHD disorders. Findings provide evidence for executive dysfunctions across different key components such as attention, response inhibition and verbal working memory in children and adolescents with ASD and comorbid ADHD clinical symptoms. This research explores the neurocognitive profile of the comorbid condition, which is also critical for designing appropriate interventions.

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