History of Gestational Hypertension Is Associated With the Metabolic Syndrome and Masked Hypertension But Not Arterial Stiffness in Women With Essential Hypertension

Background: Risk factors can lead to clinical conditions, like metabolic syndrome, that predisposes the development of cardiovascular diseases. Objective: The goal of this population-based, prospective and non-randomised cohort study was to study the association between patients with metabolic syndrome and other various factors defining metabolic syndrome. Methods: All the patients referred to the department of Medicine, Al-Ameen Medical college hospital and District Hospital, Vijayapur, Karnataka, India over a period of twenty-two months extending from December 2013 to September 2015 were considered in this study. Results: In the current study, out of 100 patients, 62.9% patients had metabolic syndrome with positive family history of hypertension, diabetes mellitus. 70.8% patients had metabolic syndrome with positive history of smoking. 64.3% patients had metabolic syndrome with positive history of alcohol .73.9% patients had metabolic syndrome with positive history of IHD. 87% of the patients with metabolic syndrome had SBP> 130 mmHg, and 78.85% patients had DBP>85 mmHg. And metabolic syndrome was observed in 71.8% patients on anti hypertensive drugs. The mean level of total cholesterol, LDL cholesterol, triglyceride is increased whereas the mean level of anti-atherogenic HDL cholesterol is low in subjects with MS. At least one lipid abnormality was present in > 95 % of cases. Around 81% subjects with BMI <25 (out of 38) had metabolic syndrome and 58% subjects with BMI>25(out of 62) had metabolic syndrome. Conclusion: All the components defining the metabolic syndrome correlated positively with the abdominal obesity. Systolic blood pressure values were significantly higher than diastolic blood pressure in subjects with abdominal obesity. Metabolic syndrome has multiple risk factors determined by various aspects like the race, the life style, geographical factors larger study is needed to understand the correlation between various components defining it. A healthy lifestyle, that includes avoiding tobacco exposure and proper weight control, must be encouraged in this high-risk population. Keywords: Cardiovascular diseases; Overweight; Risk factors; Smoking.

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Arterial stiffness and influences of the metabolic syndrome: A cross-countries study

Atherosclerosis ◽

10.1016/j.atherosclerosis.2014.01.041 ◽

2014 ◽

Vol 233 (2) ◽

pp. 654-660 ◽

Cited By ~ 86

Author(s):

Angelo Scuteri ◽

Pedro G. Cunha ◽

E. Agabiti Rosei ◽

Jolita Badariere ◽

Sofie Bekaert ◽

...

Keyword(s):

Metabolic Syndrome ◽

Arterial Stiffness ◽

The Metabolic Syndrome

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Elevated C-Reactive Protein Augments Increased Arterial Stiffness in Subjects With the Metabolic Syndrome

Hypertension ◽

10.1161/01.hyp.0000165018.63523.8a ◽

2005 ◽

Vol 45 (5) ◽

pp. 997-1003 ◽

Cited By ~ 63

Author(s):

Hirofumi Tomiyama ◽

Yutaka Koji ◽

Minoru Yambe ◽

Kohki Motobe ◽

Kazuki Shiina ◽

...

Keyword(s):

Metabolic Syndrome ◽

Arterial Stiffness ◽

C Reactive Protein ◽

Reactive Protein ◽

The Metabolic Syndrome

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Prevalence of Diastolic Dysfunction in Non Diabetic Patients of Metabolic Syndrome

10.21203/rs.3.rs-331297/v1 ◽

2021 ◽

Author(s):

Kaushiki Kirty ◽

Prabha Adhikari

Keyword(s):

Metabolic Syndrome ◽

Risk Factor ◽

Diastolic Dysfunction ◽

Strong Correlation ◽

Past History ◽

Diabetic Patients ◽

Short Term ◽

The Metabolic Syndrome ◽

History Of

Abstract Background :The purpose of the present study was to study the prevalence of metabolic syndrome in non diabetic patients of metabolic syndrome Materials and Methods: 100 patients of non diabetic metabolic syndrome were screened using 2-D Echocardiogram.Results: 34% of non diabetic patients of metabolic syndrome had diastolic dysfunction, with no association found between the components of metabolic syndrome and diastolic dysfunction. There was a strong correlation between a past history of hypertension and dyslipidemia with diastolic dysfunction.Conclusion: Our findings suggest that long standing metabolic syndrome is a risk factor for diastolic dysfunction, rather than short term elevation of the metabolic syndrome parameters. Also it is likely that Diabetes and Prediabetes itself is responsible for most of the diastolic dysfunction that is seen in metabolic syndrome

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Family History of Diabetes and Prevalence of the Metabolic Syndrome in U.S. Adults without Diabetes: 6-Year Results from the National Health and Nutrition Examination Survey (1999–2004)

Public Health Genomics ◽

10.1159/000262330 ◽

2009 ◽

Vol 13 (6) ◽

pp. 353-359 ◽

Cited By ~ 11

Author(s):

A. Ghosh ◽

T. Liu ◽

M.J. Khoury ◽

R. Valdez

Keyword(s):

Metabolic Syndrome ◽

Family History ◽

National Health ◽

Nutrition Examination Survey ◽

Family History Of Diabetes ◽

Health And Nutrition ◽

The Metabolic Syndrome ◽

History Of

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ADIPONECTIN BLOOD LEVEL AT PATIENTS WITH ESSENTIAL HYPERTENSION AND THE METABOLIC SYNDROME DURING OLMESARTAN THERAPY DINAMICS: PP.34.380

Journal of Hypertension ◽

10.1097/01.hjh.0000379918.57361.11 ◽

2010 ◽

Vol 28 ◽

pp. e564

Author(s):

S Koval ◽

I Snegurskaya ◽

O Mysnychenko ◽

D Miloslavsky

Keyword(s):

Metabolic Syndrome ◽

Essential Hypertension ◽

Blood Level ◽

The Metabolic Syndrome

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P808Characteristics of patients with reproducible masked hypertension

European Heart Journal ◽

10.1093/eurheartj/ehz747.0407 ◽

2019 ◽

Vol 40 (Supplement_1) ◽

Author(s):

M I Smirnova ◽

V M Gorbunov ◽

D A Volkov ◽

Y N Koshelyaevskaya ◽

A D Deev ◽

...

Keyword(s):

Arterial Stiffness ◽

Aortic Pressure ◽

Cardiovascular Complications ◽

Masked Hypertension ◽

Ambulatory Bp Monitoring ◽

Oscillometric Device ◽

The Family ◽

Ambulatory Patients ◽

History Of ◽

Family History Of Hypertension

Abstract Background Masked hypertension (MH) is associated with cardiovascular complications and poor prognosis. Characteristics of untreated patients with reproducible MH are studied insufficiently. Purpose The aim of our study was to assess characteristics of ambulatory patients with reproducible MH in comparison to patients with non-reproducible MH in two visits. Methods The patients from the ambulatory BP monitoring (ABPM) database (>2000 patients) were selected according to the following criteria: absence of any antihypertensive treatment (AHT), availability of clinical BP (CBP) and ABPM records at two visits with the 6 months interval, CBP<140 and 90 mmHg at both visits, availability of clinical, anthropometric data and history. MH criteria in each patients should be present at least at one of the visits. ABPM was performed by the oscillometric device equipped with software for arterial stiffness calculation. The standard statistical methods and analysis of variance (ANOVA) were used. Results We selected 295 patients (men 43%, mean age 49.0±7.6 years, CBP 128.4±9.4/80.5±7.2 mm Hg, body mass index 27.6±4.3 kg/m2, 24h pulse wave velocity in aorta [PWV] 10.7±1.7 m/s). MH only at one visit was found in 168 patients (56.9%). Respectively, MH at both visits was in 127 patients (43.1%). The patients with reproducible MH were characterized by the presence of: mother's (p=0.011) or father's hypertension (p=0.025), mother's ischemic heart disease (p=0.015), mother's myocardial infarction (p=0.020), father's stroke (p=0.030), higher arterial stiffness (PWV 11.0±1.7 m/s vs. 10.5±1.8 m/s, p=0.022), and systolic BP in aorta (120.0±7.5 mmHg vs. 117.8±9.4 mm Hg). Conclusions The patients with reproducible MH (without AHT) are characterized most of all by the family history of hypertension and its complications. The correlation of stable MH with arterial stiffness confirms the importance of PWV and central aortic pressure measurement in patients with CBP<140 and 90 mmHg.

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