scholarly journals Expression patterns of programmed cell death 4 protein in normal human skin and some representative skin lesions

2007 ◽  
Vol 16 (3) ◽  
pp. 179-184 ◽  
Author(s):  
Sachiko Matsuhashi ◽  
Yutaka Narisawa ◽  
Iwata Ozaki ◽  
Toshihiko Mizuta
2006 ◽  
Vol 131 (4) ◽  
pp. 521-524 ◽  
Author(s):  
Y. TAMADA ◽  
H. TAKAMA ◽  
T. KITAMURA ◽  
K. YOKOCHI ◽  
Y. NITTA ◽  
...  

2001 ◽  
Vol 14 (4) ◽  
pp. 289-297 ◽  
Author(s):  
Victoria Virador ◽  
Naoko Matsunaga ◽  
Jun Matsunaga ◽  
Julio Valencia ◽  
Roger J. Oldham ◽  
...  

2016 ◽  
Vol 12 (4) ◽  
pp. 2976-2981 ◽  
Author(s):  
Xia Zhang ◽  
Riming Liu ◽  
Baohua Huang ◽  
Xiaolu Zhang ◽  
Weijuan Yu ◽  
...  

1984 ◽  
Vol 12 (2) ◽  
pp. 89-97
Author(s):  
Graham R. Elliott ◽  
H.E. Amos ◽  
James W. Bridges

The rate of growth of normal human skin fibroblasts was inhibited in a dose related, reversible, fashion by practolol (N-4-(2-hydroxy)-3 (1-methyl)-aminopropoxyphenylacetamine) (ID50 1.35 ± 0.14 x 10-3M), propranolol (1-(isopropylamino)-3(1-naphthyl-oxy)-2-propranolol) (ID50 0.145 ± 0.02 x 10-3M) and paracetamol (N-(4-hydroxyphenyl) acetamide) (ID50 0.85 ± 0.2 x 10-3M). Skin fibroblasts isolated from a psoriasis patient were more sensitive towards practolol (ID50 0.48 ± 0.14 x 10-3M) and propranolol (ID50 0.032 ± 0.002 x 10-3M), but less sensitive towards paracetamol (ID50 1.3 ± 0.07 x 10-3M). In vitro generated metabolites of practolol, using normal or Arochlor 1254-pretreated hamster liver preparations, and structural analogues of practolol had no effect upon the growth of either cell type.


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