Introduction adolescents represent a vulnerable group exposed to sexually transmitted infections including HIV/AIDS. It is a stage in which they are subjected to constant changes in physical, mental and social development and risk factors such as ignorance, early sex, drug addiction, social inequality, gender and myths contribute to this exposure. Objective: To delve into the characteristics of adolescents that put them at risk of acquiring an STI-HIV/AIDS. Methods: A bibliographic review was carried out where the databases included in the LILACS, EBSCO and HINARI services were consulted, and very good coverage was achieved, both in Cuba, Latin America and the Caribbean, and in the rest of the world. Conclusions: This review article on the risks to which adolescents are subjected to acquiring an STI-HIV/AIDS is put in the hands of all personnel involved in working with adolescents. For the family doctor in particular for being a staff closely linked to the community, allowing them to be in better conditions to detect these behaviors thus contributing to exercise and undertake prevention actions that will allow us to achieve the objectives of our Ministry of Public Health in relation to with this indicator.