Estimation of the stability of dry horse serum cholinesterase by means of an accelerated storage test

1968 ◽  
Vol 20 (1) ◽  
pp. 48-53 ◽  
Author(s):  
B. R. COLE ◽  
L. LEADBEATER
Keyword(s):  
Horse Serum ◽  
Serum Cholinesterase ◽  
Storage Test ◽  
Accelerated Storage ◽  
The Stability ◽  
Accelerated Storage Test

scholarly journals Stability studies of mefenamic acid Self-Nanoemulsifying Drug Delivery System (SNEEDS) preparation with oleic acid as the oil phase

2020 ◽  
Vol 16 (2) ◽  
pp. 130-143
Author(s):  
Yandi Syukri ◽  
Septiani Eka Cahyani ◽  
Bambang Hernawan Nugroho
Keyword(s):  
Oleic Acid ◽  
Mefenamic Acid ◽  
Tween 80 ◽  
Stability Studies ◽  
Storage Test ◽  
Peg 400 ◽  
Accelerated Storage ◽  
The Stability ◽  
Accelerated Storage Test

Background: Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) with low solubility in water. Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) play a role to improve the solubility and bioavailability of mefenamic acid. Objective: This study aimed to determine the stability of mefenamic acid in SNEDDS formulation through various stability studies. Methods: The stability studies conducted consisted of centrifugation test, heating-cooling cycle test, freezethaw cycle test, robustness to dilution, accelerated storage test, and determination of drug content. Results: The centrifugation test, heating-cooling cycle test, and freeze-thaw cycle test showed no phase separation in the samples. The robustness to dilution and accelerated storage test resulted in 2 formulas of mefenamic acid loaded SNEDDS having good stability with 10% oleic acid, 80% tween 80, 10% PEG 400 and 10% oleic acid, 70% tween 80, 20% PEG 400. The determination of drug content in both of these formulations showed 98.20 ± 0.04% and 90.98 ± 0.06%. Conclusion: The SNEDDS formulation of mefenamic acid in this study had good stability. Keywords: SNEDDS, mefenamic acid, stability study, oleic acid

FACTORS AFFECTING THE STORAGE OF DEHYDRATED PORK

1945 ◽  
Vol 23f (1) ◽  
pp. 9-21
Author(s):  
Jesse A. Pearce
Keyword(s):  
Storage Temperature ◽  
Storage Test ◽  
Factors Affecting ◽  
Accelerated Storage ◽  
Relative Value ◽  
Keeping Quality ◽  
P 16 ◽  
One Year ◽  
Accelerated Storage Test

In an accelerated storage test at 60 °C. fat levels of 20 and 30% were observed to have no effect on keeping quality of dehydrated pork. Measurements on dried product stored in paper-bodied containers for one year at temperatures from −17.8 °C. to 36.7 °C. showed 15.6 °C. to be less desirable than 23.9°, 0°, or −17.8 °C. Dehydrated pork was stored in tin-plate containers for periods of one year at 23.9 °C. and 36.7 °C. with little decrease in palatability. No difference in storage life was demonstrated between cured and uncured pork, or, as a result of differences in drying times, moisture content |or storage temperature. The product prepared on an atmospheric double-drum drier deteriorated a little more rapidly than vacuum–tray- or tunnel–tray-dried material. The effectiveness of container materials, tin-plate, Reynolds' metal A-10, Dewey and Almy P-16, and 300 MST cellophane, was evaluated and their relative value for dehydrated pork fell in that order.

Application of accelerated storage test to lyophilized plant viruses

1996 ◽  
Vol 10 (12) ◽  
Author(s):  
Angela Yordanova ◽  
Elisaveta Stoimenova ◽  
Todor Donev
Keyword(s):  
Plant Viruses ◽  
Storage Test ◽  
Accelerated Storage ◽  
Accelerated Storage Test

CIPAC Collaborative Study of the Heat-Stability of Diazinon Formulations, Using Both CIPAC and AOAC Analytical Methods

1974 ◽  
Vol 57 (1) ◽  
pp. 48-52 ◽  
Author(s):  
Dieter O Eberle ◽  
Rolf Suter ◽  
Klaus Nowak ◽  
Hans P Bosshardt
Keyword(s):  
Good Accuracy ◽  
Collaborative Study ◽  
Heat Stability ◽  
The United States ◽  
Storage Test ◽  
Accelerated Storage ◽  
Before And After ◽  
Aoac Official ◽  
Gas Chromatographic Method ◽  
Accelerated Storage Test

Abstract Diazinon (O,O-diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate) and 3 different Diazinon formulations were analyzed both by the official CIPAC titrimetric method and by the AOAC official first action gas chromatographic method. In addition, all samples were subjected to the CIPAC accelerated storage test by heating (2 weeks at 54°C) and analyzed by the 2 methods before and after storage. Eight collaborators from European countries and the United States took part in the study. Analytical results were reproducible within and between laboratories by both methods. As demonstrated by an analysis of variance, the 2 procedures yielded identical results. Therefore, both the CIPAC and the AOAC methods may be considered as equivalent with good accuracy and reproducibility. After storage at 54°C for 14 days only one Diazinon dust formulation revealed a significant decrease in Diazinon content as shown by a t-test.

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