scholarly journals Local oestrogen therapy modulates extracellular matrix and immune response in the vaginal tissue of post‐menopausal women with severe pelvic organ prolapse

2019 ◽  
Vol 23 (4) ◽  
pp. 2907-2919 ◽  
Author(s):  
Tanya Tyagi ◽  
May Alarab ◽  
Yvonne Leong ◽  
Stephen Lye ◽  
Oksana Shynlova
Keyword(s):  
Immune Response ◽  
Extracellular Matrix ◽  
Pelvic Organ Prolapse ◽  
Pelvic Organ ◽  
Oestrogen Therapy ◽  
Vaginal Tissue ◽  
Menopausal Women ◽  
Post Menopausal

scholarly journals Geriatric gynecology: need and spectrum

2020 ◽  
Vol 9 (6) ◽  
pp. 2556
Author(s):  
Mridula Singh ◽  
Sudha Chourasia
Keyword(s):  
Pelvic Organ Prolapse ◽  
Screening Program ◽  
Early Stage ◽  
Medical Science ◽  
Developed Countries ◽  
Pelvic Organ ◽  
Cross Sectional ◽  
Menopausal Women ◽  
Night Sweats ◽  
Post Menopausal

Background: Geriatric gynaecology deals with gynaecological pathologies essential in post-menopausal women aged 65 years and above. The spectrum of geriatric gynaecological disorders in India differs from those in developed countries as there are no effective screening program for early detection of cancer and the burden of ignorance and taboos. In this study we aim to find the spectrum of gynaecological disorders in geriatric women and establish the need of dedicated geriatric unit.Methods: A cross-sectional comparative study was conducted on menopausal women of age 45 years or above who attended gynecology OPD for general counselling about menopause or treatment of menopausal problems over the period of 6 months duration. All these menopausal women attending OPD during this interval were evaluated on the basis of pretested questionnaire.Results: Out of 234 post-menopausal women who entered the study, 29% women belong to geriatric group. Post-menopausal bleeding due to both malignant and benign causes and pelvic organ prolapse are the major problems in geriatric women whereas somatic complaints like flushing, night sweats are more common in younger menopausal women.Conclusions: Where the medical science has successfully increased the life expectancy, focused approach to geriatric gynecology around us is our responsibility, where female still hesitate to come out. The need for dedicated geriatric gynecology unit in India on urgent basis is emphasized by this study wherein cancers can be screened in early stage and severe lifestyle hampering conditions like pelvic organ prolapse can be treated timely.

scholarly journals Robot-Assisted Laparoscopic Surgery for Pelvic Organ Prolapse among Peri- and Post-Menopausal Women

2020 ◽  
Vol 26 (3) ◽  
pp. 154
Author(s):  
Ju Hee Kim ◽  
Sa Ra Lee ◽  
Eun Sil Lee ◽  
Sung Hoon Kim ◽  
Hee Dong Chae
Keyword(s):  
Laparoscopic Surgery ◽  
Pelvic Organ Prolapse ◽  
Pelvic Organ ◽  
Robot Assisted ◽  
Menopausal Women ◽  
Post Menopausal

scholarly journals Expression of estrogen receptors in the pelvic floor of pre- and post-menopausal women presenting pelvic organ prolapse

2011 ◽  
Vol 49 (3) ◽  
pp. 521-527 ◽  
Author(s):  
Monika Zbucka-Kretowska ◽  
Naama Marcus-Braun ◽  
Cyril Eboue ◽  
Geneviève Abeguile ◽  
Slawomir Wolczynski ◽  
...  
Keyword(s):  
Pelvic Organ Prolapse ◽  
Pelvic Floor ◽  
Estrogen Receptors ◽  
Pelvic Organ ◽  
Menopausal Women ◽  
Post Menopausal

The Effects of Therapy with Oestriol Succinate and Ethinyl Oestradiol on the Haemostatic Mechanism in Post-Menopausal Women

1976 ◽  
Vol 35 (02) ◽  
pp. 403-414 ◽  
Author(s):  
Terence Davies ◽  
Gillian Fieldhouse ◽  
George P. McNicol
Keyword(s):  
Coagulation Factors ◽  
Factor Vii ◽  
Oestrogen Therapy ◽  
Qualitative And Quantitative ◽  
Lysis Activity ◽  
Menopausal Women ◽  
Increased Sensitivity ◽  
Post Menopausal ◽  
Incremental Increase ◽  
Ethinyl Oestradiol

SummaryThe effects on the haemostatic mechanism of oestrogen therapy, given to prevent bone loss in post-menopausal women, have been investigated. Oestriol succinate was given orally to 10 women at a level of 2 mg/day for 1 month and for a further 3 months with incremental increase of 2 mg each month. 6 of the 10 women were subsequently treated with 25 μg/day orally of ethinyl oestradiol. Oestriol succinate therapy resulted in a small increase in the level of factor VII, a decrease in factor VIII concentration and increased sensitivity of platelets to aggregating agents. Ethinyl oestradiol treatment resulted in much more widespread changes with marked increases in coagulation factors VII, VIII, IX and X, decreased levels of antithrombin and dramatic increases in circulating plasminogen levels and euglobulin lysis activity. The data suggested that the nature of oestrogens employed therapeutically is important in determining the qualitative and quantitative effect of oestrogen therapy on components of the haemostatic mechanism.

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