A through‐focus scanning optical microscopy dimensional measurement method based on deep‐learning classification model

2021 ◽  
Author(s):  
Nie Haitao ◽  
Peng Renju ◽  
Ren Jiajun ◽  
Qu Yufu

2020 ◽  
Vol 47 (12) ◽  
pp. 1204005
Author(s):  
伍俊龙 Wu Junlong ◽  
郭正华 Guo Zhenghua ◽  
陈先锋 Chen Xianfeng ◽  
马帅 Ma Shuai ◽  
晏旭 Yan Xu ◽  
...  


1996 ◽  
Vol 444 ◽  
Author(s):  
Maarten P. de Boer ◽  
Terry A. Michalske

AbstractWe have measured autoadhesion (e.g. stiction) of individual polysilicon beams by interferometric optical microscopy. Untreated cantilever beams were dried from water in air, while treated beams were coated with a hydrophobic molecular coating of octadecyltrichlorosilane (ODTS). Adhesion values obtained for beams adhered to the substrate over a long length (large d) are independent of beam length with values of 16.7 and 4.4 mJ/m2 for untreated and treated samples respectively. These values can be understood in terms of differences in surface chemistry and polysilicon roughness. Using the shortest length beam which remains attached to the substrate, adhesion values were 280 and 16 mJ/m2 respectively. These higher values may be a result of capillarity effects. We recommend that measurements be made on beams in which d is large, in contrast to the current practice of noting the shortest beam adhered.



2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Young-Gon Kim ◽  
Sungchul Kim ◽  
Cristina Eunbee Cho ◽  
In Hye Song ◽  
Hee Jin Lee ◽  
...  

AbstractFast and accurate confirmation of metastasis on the frozen tissue section of intraoperative sentinel lymph node biopsy is an essential tool for critical surgical decisions. However, accurate diagnosis by pathologists is difficult within the time limitations. Training a robust and accurate deep learning model is also difficult owing to the limited number of frozen datasets with high quality labels. To overcome these issues, we validated the effectiveness of transfer learning from CAMELYON16 to improve performance of the convolutional neural network (CNN)-based classification model on our frozen dataset (N = 297) from Asan Medical Center (AMC). Among the 297 whole slide images (WSIs), 157 and 40 WSIs were used to train deep learning models with different dataset ratios at 2, 4, 8, 20, 40, and 100%. The remaining, i.e., 100 WSIs, were used to validate model performance in terms of patch- and slide-level classification. An additional 228 WSIs from Seoul National University Bundang Hospital (SNUBH) were used as an external validation. Three initial weights, i.e., scratch-based (random initialization), ImageNet-based, and CAMELYON16-based models were used to validate their effectiveness in external validation. In the patch-level classification results on the AMC dataset, CAMELYON16-based models trained with a small dataset (up to 40%, i.e., 62 WSIs) showed a significantly higher area under the curve (AUC) of 0.929 than those of the scratch- and ImageNet-based models at 0.897 and 0.919, respectively, while CAMELYON16-based and ImageNet-based models trained with 100% of the training dataset showed comparable AUCs at 0.944 and 0.943, respectively. For the external validation, CAMELYON16-based models showed higher AUCs than those of the scratch- and ImageNet-based models. Model performance for slide feasibility of the transfer learning to enhance model performance was validated in the case of frozen section datasets with limited numbers.



Computers ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 82
Author(s):  
Ahmad O. Aseeri

Deep Learning-based methods have emerged to be one of the most effective and practical solutions in a wide range of medical problems, including the diagnosis of cardiac arrhythmias. A critical step to a precocious diagnosis in many heart dysfunctions diseases starts with the accurate detection and classification of cardiac arrhythmias, which can be achieved via electrocardiograms (ECGs). Motivated by the desire to enhance conventional clinical methods in diagnosing cardiac arrhythmias, we introduce an uncertainty-aware deep learning-based predictive model design for accurate large-scale classification of cardiac arrhythmias successfully trained and evaluated using three benchmark medical datasets. In addition, considering that the quantification of uncertainty estimates is vital for clinical decision-making, our method incorporates a probabilistic approach to capture the model’s uncertainty using a Bayesian-based approximation method without introducing additional parameters or significant changes to the network’s architecture. Although many arrhythmias classification solutions with various ECG feature engineering techniques have been reported in the literature, the introduced AI-based probabilistic-enabled method in this paper outperforms the results of existing methods in outstanding multiclass classification results that manifest F1 scores of 98.62% and 96.73% with (MIT-BIH) dataset of 20 annotations, and 99.23% and 96.94% with (INCART) dataset of eight annotations, and 97.25% and 96.73% with (BIDMC) dataset of six annotations, for the deep ensemble and probabilistic mode, respectively. We demonstrate our method’s high-performing and statistical reliability results in numerical experiments on the language modeling using the gating mechanism of Recurrent Neural Networks.



2021 ◽  
Vol 11 (9) ◽  
pp. 3952
Author(s):  
Shimin Tang ◽  
Zhiqiang Chen

With the ubiquitous use of mobile imaging devices, the collection of perishable disaster-scene data has become unprecedentedly easy. However, computing methods are unable to understand these images with significant complexity and uncertainties. In this paper, the authors investigate the problem of disaster-scene understanding through a deep-learning approach. Two attributes of images are concerned, including hazard types and damage levels. Three deep-learning models are trained, and their performance is assessed. Specifically, the best model for hazard-type prediction has an overall accuracy (OA) of 90.1%, and the best damage-level classification model has an explainable OA of 62.6%, upon which both models adopt the Faster R-CNN architecture with a ResNet50 network as a feature extractor. It is concluded that hazard types are more identifiable than damage levels in disaster-scene images. Insights are revealed, including that damage-level recognition suffers more from inter- and intra-class variations, and the treatment of hazard-agnostic damage leveling further contributes to the underlying uncertainties.



Sensors ◽  
2021 ◽  
Vol 21 (9) ◽  
pp. 3279
Author(s):  
Maria Habib ◽  
Mohammad Faris ◽  
Raneem Qaddoura ◽  
Manal Alomari ◽  
Alaa Alomari ◽  
...  

Maintaining a high quality of conversation between doctors and patients is essential in telehealth services, where efficient and competent communication is important to promote patient health. Assessing the quality of medical conversations is often handled based on a human auditory-perceptual evaluation. Typically, trained experts are needed for such tasks, as they follow systematic evaluation criteria. However, the daily rapid increase of consultations makes the evaluation process inefficient and impractical. This paper investigates the automation of the quality assessment process of patient–doctor voice-based conversations in a telehealth service using a deep-learning-based classification model. For this, the data consist of audio recordings obtained from Altibbi. Altibbi is a digital health platform that provides telemedicine and telehealth services in the Middle East and North Africa (MENA). The objective is to assist Altibbi’s operations team in the evaluation of the provided consultations in an automated manner. The proposed model is developed using three sets of features: features extracted from the signal level, the transcript level, and the signal and transcript levels. At the signal level, various statistical and spectral information is calculated to characterize the spectral envelope of the speech recordings. At the transcript level, a pre-trained embedding model is utilized to encompass the semantic and contextual features of the textual information. Additionally, the hybrid of the signal and transcript levels is explored and analyzed. The designed classification model relies on stacked layers of deep neural networks and convolutional neural networks. Evaluation results show that the model achieved a higher level of precision when compared with the manual evaluation approach followed by Altibbi’s operations team.



2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Xinyang Li ◽  
Guoxun Zhang ◽  
Hui Qiao ◽  
Feng Bao ◽  
Yue Deng ◽  
...  

AbstractThe development of deep learning and open access to a substantial collection of imaging data together provide a potential solution for computational image transformation, which is gradually changing the landscape of optical imaging and biomedical research. However, current implementations of deep learning usually operate in a supervised manner, and their reliance on laborious and error-prone data annotation procedures remains a barrier to more general applicability. Here, we propose an unsupervised image transformation to facilitate the utilization of deep learning for optical microscopy, even in some cases in which supervised models cannot be applied. Through the introduction of a saliency constraint, the unsupervised model, named Unsupervised content-preserving Transformation for Optical Microscopy (UTOM), can learn the mapping between two image domains without requiring paired training data while avoiding distortions of the image content. UTOM shows promising performance in a wide range of biomedical image transformation tasks, including in silico histological staining, fluorescence image restoration, and virtual fluorescence labeling. Quantitative evaluations reveal that UTOM achieves stable and high-fidelity image transformations across different imaging conditions and modalities. We anticipate that our framework will encourage a paradigm shift in training neural networks and enable more applications of artificial intelligence in biomedical imaging.



Author(s):  
Ala Addin I. Sidig ◽  
Hamzah Luqman ◽  
Sabri Mahmoud ◽  
Mohamed Mohandes

Sign language is the major means of communication for the deaf community. It uses body language and gestures such as hand shapes, lib patterns, and facial expressions to convey a message. Sign language is geography-specific, as it differs from one country to another. Arabic Sign language is used in all Arab countries. The availability of a comprehensive benchmarking database for ArSL is one of the challenges of the automatic recognition of Arabic Sign language. This article introduces KArSL database for ArSL, consisting of 502 signs that cover 11 chapters of ArSL dictionary. Signs in KArSL database are performed by three professional signers, and each sign is repeated 50 times by each signer. The database is recorded using state-of-art multi-modal Microsoft Kinect V2. We also propose three approaches for sign language recognition using this database. The proposed systems are Hidden Markov Models, deep learning images’ classification model applied on an image composed of shots of the video of the sign, and attention-based deep learning captioning system. Recognition accuracies of these systems indicate their suitability for such a large number of Arabic signs. The techniques are also tested on a publicly available database. KArSL database will be made freely available for interested researchers.



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